Mankhwala a Bagomet kuphatikiza ndi ophatikizika awiri a mankhwala amkamwa a hypoglycemic nthawi imodzi, omwe ali m'magulu osiyanasiyana a mankhwala: Metformin, Glibenclamide.
Metformin ndi mankhwala a gulu la Biguanide, amatsitsa glycemia chifukwa cha kuchuluka kwa ziwopsezo za zotumphukira kwa insulin ya mahomoni, kukweza kwa glucose.
Zinthu zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimachepetsa mayamwidwe am'mimba kudzera m'mimba, zimalepheretsa gluconeogeneis m'chiwindi cha wodwalayo, ndipo zimathandizira pakupezeka kwamagazi, kutsitsa triglycerides ndi cholesterol yonse.
Glibenclamide ndi sulfonylurea ya m'badwo wachiwiri, kuchuluka kwa glucose pambuyo pogwiritsa ntchito kumachepa chifukwa cha chinsinsi cha insulin ya mahomoni mwa maselo a kapamba.
Mukatha kugwiritsa ntchito mankhwalawa, zotsatira za hypoglycemic zimayamba pambuyo pa maola awiri, ndipo zimatha mpaka maola 12. Chizindikiro chachikulu chogwiritsidwa ntchito ndi mtundu wa 2 shuga wodwala mellitus motsutsana ndi kumbuyo kwa kusowa kwa zotsatira kuchokera pakudya kapena chithandizo chamankhwala chamlomo.
Mtengo wa Bagomet Plus (Mlingo wa 500 mg) ndi pafupifupi ma ruble 200. Analogs a mankhwalawa: Glybomet, Glukovans, Gluconorm.
Chachikulu contraindication, zoyipa zimachitika thupi
Mankhwala sangalembedwe mtundu 1 shuga, matenda a shuga, chikomokere, matenda ashuga ketoacidosis, aimpso ndi kwa chiwindi kulephera, lactic acidosis, pachimake mowa. Bagomet siyikulimbikitsidwanso kuti ikhale yovuta kwambiri ya pathological yomwe imafunikira kuyambitsidwa kwa ayodini okhala ndi zotsutsana.
Mankhwalawa ali contraindicated mu aakulu ndi pachimake zinthu, amene limodzi ndi mpweya njala, awa: mantha boma, myocardial infarction, madzi osowa madzi. Palinso zoletsa kugwiritsa ntchito mankhwalawa porphyria, kugwiritsa ntchito pamodzi ndi miconazole, kutenga pakati, ndi kuyamwitsa.
Ndizotheka kuti pakumwa mankhwalawa wodwala yemwe ali ndi matenda ashuga amadzakumana ndi zovuta zosagwirizana ndi thupi: kusanza, kusanza, kupweteka kwam'mimba, kuchepa kwa chakudya, kulawa kwazitsulo mkamwa, komanso khunyu. Metformin mu kapangidwe ka mankhwala nthawi zina imayambitsa kuchepa kwa mayamwidwe, lactate acidosis.
Gawo lina la mankhwala a Bagomet - Glibenclamide - amatha kupangitsa zinthu izi:
- zotupa pakhungu, kuyabwa, urticaria;
- kusanza, nseru, m'mimba kupweteka;
- kuchuluka kwa hepatic transaminases;
- leukopenia, hemolytic anemia, thrombocytopenia.
Kuchuluka kwa magazi urea ndende, m`mafupa aplasia, pancytopenia, hyponatremia, disulfiram ngati zimachitika.
Malangizo ogwiritsira ntchito mankhwalawa
Bagomet Plus imatengedwa ndi chakudya, njira yeniyeni ya mankhwalawa imayenera kusankhidwa payekha, kutengera mtundu wa njira za metabolic. Monga lamulo, mlingo woyambirira ndi piritsi limodzi, pang'onopang'ono kuchuluka kwa mankhwalawa kumawonjezereka, kutengera zomwe zikuwonetsa glycemic. Nthawi zambiri zimatenga milungu iwiri.
Ngati pakufunika kusintha njira yothandizira kuphatikiza, dokotala amakupatsani mapiritsi a 1-2 (mlingo wake umatengera mlingo wapitawo wa mankhwalawo). Mapiritsi okwanira 4 amaloledwa patsiku, kutengera zinthu zazikulu zogwira - izi 500 mg za metformin ndi 5 mg ya glibenclamide.
Ngati wodwala matenda a shuga wachitidwa opaleshoni, akuwotcha, kuvulala kapena matenda opatsirana omwe ali ndi vuto lotupa, mungafunike kusiya kumwa mankhwala akumwa a hypoglycemic ndikupereka jakisoni wa insulin.
Munthawi yamankhwala, mukuyenera kuyang'aniridwa:
- kusala kudya glycemia, mutatha kudya;
- tsiku lililonse lopindika shuga.
Muyenera kudziwa zakuwonjezereka kwa kukhala ndi hypoglycemia ngati wodwala matenda ashuga, limodzi ndi Bagomet Plus, amamwa mowa, osagwiritsa ntchito mankhwala osokoneza bongo, ndipo akumva njala.
Kusintha kwa mankhwalawa kwa mankhwalawa kumaperekedwa chifukwa cha nkhawa, kupsinjika kwakuthupi, kusintha kwakanthawi kwamasamba. Mosamala kwambiri, mankhwalawa amayenera kumwedwa motsutsana ndi maziko a mankhwalawa ndi othandizira odwala beta.
Ngati zizindikiro za hypoglycemia zikuchitika, akuwonetsedwa:
- idyani chakudya chochepa chamafuta;
- gwiritsirani ntchito shuga kapena dextrose solution kudzera m'mitsempha.
Pakufunika kafukufuku wa urographic kapena angiographic, Bagomet Plus imathetsedwa masiku awiri isanachitike ndendende ndikuyambiranso patatha maola 48.
Ndi kugwiritsidwa ntchito komweko kwa zinthu zomwe zimakhala ndi ethanol, pali mwayi wopanga mawonekedwe a discriram.
Pakutalika kwa chithandizo, wodwala matenda ashuga amayenera kusamala kwambiri poyendetsa mitundu yosiyanasiyana ya mayendedwe, kugwira ntchito ndi njira zoopsa zomwe zimaphatikizapo chidwi chochulukirapo, komanso kuthamanga kwa zochitika zama psychomotor.
Kuyanjana kwa mankhwala osokoneza bongo
Kugwiritsa ntchito limodzi ndi miconazole kungayambitse kukula kwa vuto la hypoglycemia, mpaka mpaka kukomoka. Ngati Bagomet imagwiritsidwa ntchito limodzi ndi Fluconazole, pali mwayi wa hypoglycemia, popeza kuchuluka kwa zotuluka ka sulfonylurea kumawonjezeka.
Mankhwala Phenylbutazone amatha kuthamangitsa zochokera ku sulfonylurea, potero amachititsa kuchuluka kwawo m'magazi, ngozi ya hypoglycemia.
Kugwiritsa ntchito mankhwala a iodine okhala ndi ayodini kungayambitse kukula kwa impso, kudzikundikira kwa metformin. Pankhaniyi, kukula kwa lactic acidosis sikuphatikizidwa. Mankhwala omwe adalandira mankhwalawa akuwonetsedwa kuti ayenera kudziwika masiku awiri asanagwiritse ntchito mankhwalawa, ndipo amatha kuyambiranso pokhapokha maola 48.
Kuchiza kwa Bagomet pogwiritsa ntchito mankhwala okhala ndi ethanol m'magulu ena a odwala omwe ali ndi matenda ashuga kumatha kupangitsa kuti anthu asamayankhe.
Bagomet Plus yofanana ndi Metformin 850 kapena 1000.
Momwemonso kugwiritsa ntchito glucocorticosteroid mankhwala, okodzetsa ndi beta2-blockers:
- pali kuchepa kwakukulu pakuyenda bwino kwa mankhwala;
- pali zisonyezo zosinthira kuchuluka kwa mankhwala.
Potengera momwe mankhwalawo amathandizira ndi ACE zoletsa, mwayi wa hypoglycemia umawonekera, beta-blockers imakulitsa pafupipafupi komanso kuopsa kwa matendawa.
Ngati mankhwala a antibacterial agwiritsidwa ntchito, kutsika msanga kwa shuga kungayambike, mankhwalawa akuphatikizapo:
- sulfonamides;
- Mao zoletsa;
- Pentoxifylline;
- Chloramphenicol;
- Kutulutsa mawu.
Zoterezi zimachitikanso pogwiritsa ntchito mankhwala ochepetsa lipid kuchokera pagulu la mafupa.
Milandu yambiri
Pankhani ya bongo, hypoglycemia imachitika, amayamba chifukwa cha glibenclamide mu chinthu.
Chifukwa chake hypoglycemia mu shuga ingayambitse njala, thukuta kwambiri, kufooka kwa minofu, khungu lotuwa, kunjenjemera m'thupi, kupweteka mutu.
Hypoglycemia ikamayenda, pamakhala ngozi yotha kudziletsa komanso kusazindikira bwino. Pankhaniyi, ndikofunikira kudya zakudya zochepa zamatumbo, jekeseni shuga m'magazi. Komabe, njirayi ingapindule pokhapokha pokhazikika pa hypoglycemia.
Mawonetsedwe ena ayenera kutchedwa:
- vuto la kugona;
- mantha opanda pake;
- gait, chiwonetsero cha kayendedwe;
- minyewa yamitsempha yama minyewa;
- chizungulire.
Zizindikiro zoopsa za hypoglycemia, ngati wodwala matenda ashuga afunika, ayenera kupaka 40% dextrose solution kapena glucagon subcutaneally, kudzera m'mitsempha kapena m'mitsempha. Mtengo wazowongolera izi ndi kupulumutsidwa kwa moyo wa munthu.
Ndondomeko imabwezeretsa chikumbumtima, wodwalayo ayenera kudya chakudya chomwe chili ndi chakudya chamagulu ambiri, izi zitha kupewa kukonzanso kwa hypoglycemia.
Malangizo ogwiritsira ntchito Bagomet Plus akuchenjeza kuti chithandizo cha nthawi yayitali chimatha kuyambitsa zovuta monga lactic acidosis, popeza mankhwalawa amaphatikiza ndi chinthu cha metformin.
Lactic acidosis - chikhalidwe chomwe chimafuna chisamaliro chamankhwala mwachangu, chithandizo chikuchitika kokha kuchipatala. Njira yothandiza kwambiri yochotsera ndi hemodialysis.
Kanemayo munkhaniyi akukamba za zovuta zomwe zimachitika chifukwa cha matenda a shuga.
