Mankhwala ochokera ku gulu la Biguanide akhala akugwiritsidwa ntchito pochiza matenda ashuga kwa nthawi yayitali - kuyambira m'ma 1970. Chimodzi mwa izo ndi mankhwala a Siofor 500.
Chimodzi mwazinthu zabwino zazikulu za biguanides ndichakuti sizipanga insulin yowonjezereka ndi kapamba. Zotsatira zazikulu zimachitika chifukwa chopinga cha gluconeogeneis.
Ma biguanides onse, kuphatikiza ndi Siofor (chithunzi), ali ndi gawo limodzi lokhazikika - metformin hydrochloride, chosiyanitsa ndi kusowa kwa hypoglycemia. Ndi zovuta zoyipa zomwe zimakonzekera kukonzedwa kwa sulfonylurea.
Momwe mungatenge Siofor 500 ndi matenda a shuga ndipo angagwiritsidwe ntchito kuti muchepetse kunenepa?
Chipangizo chachipatala ndi chiyani?
Chithandizo cha matenda ashuga nthawi zambiri chimakhala ndi zovuta kuchipatala, zomwe mosakayikira zimakhala ndi kumwa mankhwala.
Mankhwala Siofor amadziwika kuti ndi amodzi mwa mankhwala othandiza kuchepetsa shuga.
Chofunikira chachikulu pa mapiritsi oterewa ndi mankhwala a metformin hydrochloride, omwe samangokhala ndi mphamvu ya hypoglycemic, komanso amakhalanso ndi mwayi wosaneneka.
Zizindikiro zazikulu zogwiritsira ntchito mankhwalawa:
- ndikupanga mankhwala osokoneza bongo omwe samadalira insulin ngati monotherapy kapena ngati gawo la chithandizo chovutaꓼ
- Kuchepetsa thupi kwa odwala matenda ashuga kuti kuchitika kwa zakudya sizinabweretse zotsatira zoyenera
- monga chida china chowonjezera cha insulin.
Kugwiritsa ntchito bwino mankhwalawa kumatheka pokhapokha thupi likupitiliza kupanga zake zake zokha kapena mahomoni akabayidwa.
Ubwino wa mankhwalawa ndi awa:
- Mankhwala omwe adapangidwira amakhudza mwachindunji kuchepa kwa insulin. Komanso, izi zimawonedwa pakapita nthawi yochepa atayamba kumwa mankhwala. Zotsatira zake ndikuwonjezera mphamvu ya maselo ndi minyewa yake kumadzi, zomwe zimapangitsa kuti shuga agwiritsidwe ntchito kwambiri.
- Popeza kukonzekera kwa piritsi kuyenera kumwedwa pakamwa, kumakomoka kudzera m'matumbo am'mimba, omwe amachepetsa kuyamwa kwa glucose kuchokera m'matumbo, chifukwa chomwe kulibe kudumphira shuga. Kutsika kwa shuga kumachitika pang'onopang'ono ndipo sikupangitsa kuti hypoglycemia itukuke.
- Kuletsa kwa gluconeogenesis mu chiwindi kumachitika.
- Chifukwa cha mankhwala omwe amwedwa, kuchepa kwa chakudya kumawonedwa. Chifukwa chake, wodwalayo amayamba kudya zakudya zochepa, zomwe ndizofunikira kukhazikika thupi.
- Zotsatira zabwino za mankhwalawa pamlingo woyipa (wochepetsedwa) ndi cholesterol yabwino. Chifukwa cha njirayi, pali kuchepa kwa dyslipidemia komanso msana wa triglycerides, otsika kachulukidwe lipoproteins.
Kuphatikiza apo, njira ya lipid peroxidation imapanikizidwa, zomwe zimapangitsa kukula kwa mamolekyulu omasuka.
Ndi mitundu yanji ya mapiritsi omwe amapezeka?
Mankhwalawa Siofor amapangidwa ndi kampani yaku Germany yopanga mankhwala Berlin-Chemie AG.
Malangizo ogwiritsira ntchito manotsi akuti mankhwalawo ali ndi mtundu umodzi wokha wa kutulutsidwa - piritsi.
Makampani ogulitsa mankhwala akwanitsa kutulutsidwa kwa mankhwalawo m'mitundu yosiyanasiyana, yomwe ili ndi mulingo wosiyanasiyana wa othandizira.
Mpaka pano, Mlingo wotsatira wa mankhwalawa ulipo:
- Siofor 500 - mapiritsi okhala ndi mawu omwe ali ndi 500 mg metformin hydrochloride.
- Siofor 850 - mankhwala omwe ali ndi kuchuluka kwa mankhwalawa. Chosakaniza chogwira ndi 850 mg piritsi limodzi.
- Siofor 1000 - 1 gramu ya mankhwala omwe amagwira ntchito ndi gawo limodzi la piritsi.
Monga zina zomwe zimagwiritsidwa ntchito:
- piritsi lililonse lili ndi hypromellose, povidone, magnesium stearateꓼ
- Chipolopolocho chimakhala ndi hypromellose, titanium dioxide, macrogol 6000.
Kutengera ndi kuchepetsedwa kwa shuga m'magazi, katswiri wa zamankhwala amasankha mlingo wa wodwala aliyense.
Mapiritsi amagulitsidwa ku pharmacies akumatauni m'makatoni amapepala a 10, 30, 60 kapena 120. Mtengo wa mankhwala umatengera kuchuluka kwa mapiritsi ndi kuchuluka kwake. Monga lamulo, pakulongedza zidutswa 60, mtengo umasiyanasiyana 240 mpaka 300 rubles.
Zofanizira za mankhwalawa ndi mankhwalawa omwe ali ndi mankhwala othandizira metformin - Glucofage, Formmetin, Glformin.
Malangizo ogwiritsira ntchito mapiritsi
Momwe mungagwiritsire Siofor ndi nthawi yayitali njira yochizira, katswiri wa zamankhwala asankha.
Mapiritsi a Siofor 500 ali ndi mawonekedwe ake ogwiritsira ntchito ndi njira yolondola yoyendetsera. Kuyamba kwa njira yochizira kuyenera kukhala ndi kuchuluka kwa mankhwalawa. Monga lamulo, iyi ndi gramu imodzi ya zinthu zomwe zimagwiritsidwa ntchito (mapiritsi awiri) patsiku chakudya chachikulu kapena pambuyo pake.
Mankhwala amatengedwa pakamwa, kutsukidwa ndi madzi amchere ambiri. Mlingo watsiku ndi tsiku uyenera kugawidwa pawiri - m'mawa ndi madzulo. Malowa ayenera kuwonedwa kwa masiku atatu oyambirira a mankhwala, pambuyo pake kuchuluka kwa mapiritsi kumawonjezeka.
Monga lamulo, kuyambira tsiku lachinayi ndi milungu iwiri yotsatira, mankhwalawa amatengedwa gramu imodzi katatu patsiku. Pakatha milungu iwiri, dotolo wofunsayo amawona mtundu woyenera wa mankhwalawo. Izi zitha kukhala kuchepa kwa mankhwala. Mankhwala a Siofor achire adzakhazikitsidwa malinga ndi zotsatira za mayeso ndi kuchuluka kwa shuga m'magazi ndi mkodzo.
Pamafunika nthawi yochuluka motani kumwa mapiritsi pamlingo wotere, adokotala amafunsa. Monga lamulo, galamu imodzi kapena ziwiri za chinthu chogwira ntchito patsiku ndizokwanira kusunga zotsatira zomwe mukufuna.
Ngati wodwalayo akutenga nthawi yomweyo mankhwala a insulin (osachepera 40 magawo patsiku), ndiye kuti mankhwalawa a Siofor 500 ndi ofanana ndi omwe ali pamwambapa.
Pankhaniyi, muyenera kuyang'anira kuchuluka kwa shuga m'magazi, mungafunike kuchepetsa kuchuluka kwa jakisoni wa insulin.
Ndi nthawi ziti pamene ndizoletsedwa kugwiritsa ntchito hypoglycemic wothandizira?
Musanagwiritse ntchito mankhwalawa, muyenera kuwerengera mosamala kuchuluka kwa zolakwika, mungafunike cholowa m'malo mwake.
Ma analogi omwe atha kukhala osiyanasiyana amatha kusintha mosiyanasiyana komanso kulolerana bwino.
Siofor ali ndi zotsutsana zingapo, momwe mankhwalawo amaletsedwa.
Zoletsa zomwe zikulimbikitsidwa kuti musagwiritse ntchito Siofor 500 ndi monga:
- mawonekedwe a shuga a insulin
- ngati pakukula kwa matenda a shuga a mtundu wachiwiri, kapamba amasiya kutulutsa kwake insulinꓼ
- munthawi yamakolo kapena odwala matenda ashuga
- ndi chiwonetsero cha ketoacidosisꓼ
- ngati pali vuto lalikulu la impso kapena chiwindi
- ndi myocardial infarction ndi mtima kulepheraꓼ
- Kukhazikika kwa njira zama pathological m'mapapu, zomwe zingayambitse kupuma
- matenda opatsirana oyipaꓼ
- isanachitike kapena itachitika opaleshoni kapena ngati pachitika kuvulala kulikonse
- zochitika za thupi za thupi, izi zitha kuphatikiza njira zowonongeka, monga zotupa pathologiesꓼ
- hypoxia stateꓼ
- kudalira mowa, kuphatikiza pa fomuꓼ
- lactic acidosis udindoꓼ
- ndi njala yotalikilapo kapena kutsatira zakudya zopanda thanzi zomwe zimadya tsiku ndi tsiku zopitilira 1,000 calories 1000
- mwa ana ochepera zaka khumi ndi zisanu ndi zitatu kapena atakwanitsa zaka sikitini ndi zisanu
- ngati pali chidziwitso chowonjezeka cha chinthu chimodzi kapena zingapo zomwe ndi gawo la mankhwala.
Kuphatikiza apo, monga mankhwala ena ambiri, Siofor 500 ndi yoletsedwa kumwa mkaka wokhudzana ndi mkaka wa m'mawere, popeza mankhwalawo amakhudza mwana kukula kwamwana.
Zotsatira zoyipa komanso zovuta zoyipa
Mankhwala osokoneza bongo amatha kuyambitsa mavuto osiyanasiyana.
Ichi ndichifukwa chake saloledwa kumwa mankhwala kwa anthu athanzi kuti muchepetse thupi kapena kuphwanya malangizo a dokotala.
Zotsatira zoyipa zimatha kuchitika ndi mankhwala osokoneza bongo ambiri.
Zotsatira zoyipa za Siofor 500 zitha kuwoneka kuchokera machitidwe osiyanasiyana a thupi. Zotsatira zoyipa ngati izi zimawonekera mu:
- Kutupa, kupweteka, mavuto ammimba.
- Kutsegula m'mimba.
- Kusanza, kusanza ndikothekanso.
- Kuchuluka kwa shuga m'magazi kumatha kubweretsa chisokonezo komanso kulephera kukhazikika.
- Zofooka zambiri.
- Kuperewera koyendetsa kayendedwe.
- Mutu waukulu wa matenda ashuga.
Nthawi zambiri, megaloblastic anemia kapena kusintha kwa matupi awo sagwirizana kumatha kuchitika.
Tiyeneranso kudziwa kuti kugwiritsa ntchito limodzi kwa Siofor ndi Cimeditin kumawonjezera chiopsezo cha lactic acidosis. Dokotala wopezekapo ayenera kudziwa kuchuluka kwa mankhwala omwe wodwala angagwiritsire ntchito kuti apewe kuwonetsa zolakwika kuchokera kugwiritsidwa ntchito kwawo palimodzi.
Kugwiritsa ntchito mankhwala kuti muchepetse kunenepa kwambiri
Mankhwalawa amathandizira kuchepetsa kulemera kwa odwala matenda ashuga limodzi ndi mankhwala omwe amaperekedwa pakudya komanso kuchita masewera olimbitsa thupi. Ndemanga zoterezi zimadziwika ndi makasitomala ambiri amtunduwu.
Dziwani kuti kuthandizira kwa mankhwalawa kumachitika chifukwa chakuti amathandizadi polimbana ndi anthu onenepa kwambiri omwe amapanga shuga osadalira kwenikweni kwa insulin. Tsoka ilo, ndemanga zoterezi zadzetsa mfundo yoti ngakhale azimayi athanzi kwathunthu omwe akufuna kutsitsimuka ayambe kumwa Siofor 500.
Zotsatira zake, shuga m'magazi awo amatsika, ndipo zovuta zosiyanasiyana komanso zizindikiro za hypoglycemia zimayamba kuonekera. Ichi ndichifukwa chake, munthu sayenera kusankha payekha kusankha chithandizo cha kunenepa kwambiri.
Ngati Siofor 500 adalembedwa ndi adotolo kupita kwa wodwala yemwe ali ndi matenda a shuga, zotsatira zabwino zitha kupitilizabe zoyembekezera zonse. Ndi kunenepa kwambiri komanso matenda a shuga, zotsatira za kuchepa thupi zimatha kuyambira ma kilogalamu atatu mpaka khumi pamwezi.
Zochita za piritsi zimachitika mwanjira yoti thupi limakhala kuti munthu amalakalaka zakudya zotsekemera - zinthu zophika mkate, makeke kapena maswiti. Ichi ndichifukwa chake, zakudya za tsiku ndi tsiku zimachotsa ma kilocalories owonjezera ndipo kulemera kumayamba kuchepa.
Ubwino waukulu wogwiritsira ntchito piritsi pakulimbana ndi kunenepa kwambiri ndikuwonetsa zotsatirazi:
- mwachangu, koma chopweteka thupi, kuchepa thupi;
- kuchepa kwa kulakalaka kwa zakudya za shuga ndi zovulaza (zomwe ndizoletsedwa mu shuga);
- palibe chifukwa cholemetsa thupi mopitilira muyeso kuti mutaye mapaundi ochepa, ndikokwanira kungokhala moyo wokangalika ndikuyenda zina zambiri;
- Mathandizidwe amathandizira wodwala kusintha zakudya zoyenera komanso chakudya chopatsa thanzi.
Zotsatirazi zitha kuonedwa kuti ndi njira zopewera kumwa mankhwalawa:
- Ndikofunikira kuyambitsa njira ya chithandizo pakulimbikitsidwa ndi dokotala yemwe akuwayang'anirani.
- Tiyenera kukumbukira kuti mankhwalawa ali ndi shuga wochepetsera shuga ndipo amapangidwira odwala matenda ashuga.
- Chenjerani ndi ziwonetsero zoyipa zamagetsi osiyanasiyana. Ichi ndichifukwa chake, mankhwalawa amayenera kumwa kokha pamankhwala omwe wodwala wamankhwala amapanga
Kudziyang'anira nokha ndi kusankha kwa mankhwalawa mukamamwa mankhwalawa kumatha kubweretsa zotsatira zoyipa ndi zolakwika zamkati mwanu.
Momwe mungagwiritsire Siofor kwa odwala matenda ashuga adzauzidwa ndi katswiri muvidiyoyi.