Kutulutsidwa kwa mankhwalawa Glucophage Long 500 kumachitika monga mapiritsi, omwe amaikidwa mu zidutswa 15 m'matumba a pulasitiki osindikizidwa ndi zojambulazo. Mabulosi amayikidwa m'mapaketi a 2 kapena 4 zidutswa. Mu phukusi lililonse, malangizo ogwiritsira ntchito mankhwalawa amaphatikizidwanso.
Glucophage Long 500 ndi mankhwala otchuka kwambiri a hypoglycemic pakati pa odwala matenda ashuga. Kutchuka kwake kumachitika chifukwa chogwira ntchito kwa nthawi yayitali.
Dziwani kuti ndizoletsedwa kumwa Glucofage nokha ndikusankha mulingo wa mankhwala.
Kukhazikitsidwa kwa mankhwala ndi kusankha kwa mlingo wake kumachitika ndi adotolo atatha kuyesa koyenera kwa thupi la wodwala yemwe ali ndi matenda a shuga.
Gawo lalikulu la mankhwalawa - metformin hydrochloride ndi gulu la Biguanides.
Kuphatikizika kwa mankhwalawa, mawonekedwe a kumasulidwa, kusungidwa ndi kugulitsa
Mankhwala amapangidwa ndi makampani azachipatala okha mwa mawonekedwe a piritsi.
Kunja, piritsi ili ndi mawonekedwe osinthika, mbali imodzi momwe amalemba 500 mg, zomwe zikutanthauza kuti zomwe zili mkati mwa chinthuchi, kumbali yakumbuyo pali zolemba za dzina la wopanga.
Kuphatikiza pa ntchito yogwira, mapiritsiwa amaphatikizanso mankhwala othandizira.
Zotsatirazi zimagwira ntchito yothandiza ku Glucofage Long 500:
- hypromellose;
- magnesium wakuba;
- povidone;
- carmellose sodium;
- ma cellulose pama microcrystals.
Mankhwalawa amagwiritsidwa ntchito makamaka pa matenda a shuga a 2. Pozindikira izi, adathandizira odwala ambiri kuchepetsa misempha ya m'magazi awo mwa kusintha mtundu wa shuga m'magulu awo. Komanso mankhwalawa amathandizira pakuchepetsa thupi la wodwalayo, ndipo vutoli limapezeka kawirikawiri kwa odwala matenda a shuga.
Tiyenera kudziwa kuti chipangizochi chili ndi malingaliro abwino, omwe akuwonetsa kuti si mankhwala othandizirana kwambiri, komanso amavulaza thupi. Kuunikiridwa kwa mankhwalawa kukuwonetsa kuti zotsatira zabwino za kumwa mankhwalawa zimapambana kwambiri pakuwonekera kwa zovuta zoyipa ndikupangitsa kuvulaza thupi.
Pharmodynamics ndi pharmacokinetics a mankhwalawa
Ngati mumazolowera malangizo omwe mungagwiritse ntchito mankhwalawa mwatsatanetsatane, zimadziwika bwino za kugwiritsa ntchito mankhwalawa, komanso momwe zimachitikira thupi la munthu.
Kupanga kwakukulu kwa zamankhwala zomwe zimapezeka mu glucophage kutalika 500 ndikofunikira kuti muchepetse kuchuluka kwa shuga m'magazi a anthu.
Metformin, yomwe ndi gawo la mankhwalawa, satha kulimbikitsa kupanga insulin yowonjezera ndi maselo a beta. Pachifukwa ichi, kumwa mankhwalawa sikuti kumayambitsa kukula kwa thupi mthupi. Kuchita kwa chigawo chogwira ntchito ndikufuna kuchititsa zolandilira zama cell zomwe zimadalira insulin.
Pambuyo pakutenga Glucofage Long 500, kuwonjezeka kwa chidwi cha zolandila m'maselo kuma insulin kumawonedwa, ndikupangitsa kuwonjezeka kwakukulu kwa kugwiritsidwa ntchito kwa glucose kuchokera m'madzi a m'magazi.
Kuphatikiza apo, pali kuchepa kwakukulu kwa kuchuluka kwa glucose wopangidwa ndi chiwindi maselo chifukwa cha kuyambitsa kwazomwe zimalepheretsa glycogenolysis ndi gluconeogeneis.
Metformin, yomwe ndi gawo la miyala, imapangitsa kuchepa kwa glucose kuchokera ku lumen ya m'mimba ndi maselo a khoma lamatumbo. Zomwe zimachepetsa kudya kwa mafuta m'magazi a m'magazi. Izi zimachepetsa kuchuluka kwa chakudya chamafuta m'thupi.
Metformin imayendetsa njira zomwe zimayang'anira kupanga glycogen. Kutseguka kumachitika chifukwa cha metformin pa glycogen synthetase.
Kulowetsedwa kwa chinthu chogwira ntchito mthupi kumakulitsa mphamvu ya transporter yamtundu uliwonse.
Odwala ambiri omwe amatenga Glucofage Long amawonetsa kuti mankhwalawo adawathandiza kuti azichita shuga.
Kuphatikiza apo, chidachi chimalimbikitsa kuchepa thupi, chomwe ndichofunikira pakuchiritsa matenda a shuga.
Kuphatikiza apo, mankhwalawa amathandizira:
- matenda a kagayidwe kachakudya njira;
- kuwunika kuwonongeka kwa mafuta omwe amalowa mthupi limodzi ndi chakudya;
- Naturalization a masoka limagwirira insulin kupanga, chifukwa chomwe kuchuluka kwa chakudya amachepetsa;
- magazi cholesterol magazi.
Pothandizira izi, kuwunika kwa wodwala kumveka, mwachitsanzo, kuti, ndimamwa kapena kumwa Glucofage ndipo monga chotulukapo, kulemera kwanga kwa thupi kunabwezeretsa.
Mukamamwa Glucofage, pamakhala kuchepa kwa chikhumbo, chomwe chimachepetsa kuchuluka kwa mafuta m'thupi.
Kuchepa kwa njala kumathandizira kuti wodwalayo akhale ndi shuga.
Zotsatira zoyipa ndi kuyanjana ndi mankhwala ena
Makhalidwe abwino omwe Glucophage Long 500 ali nawo afotokozedwa kale pamwambapa.
Tsopano muyenera kufotokozera zovuta zomwe mankhwalawa atha kukhala nazo, komanso pazomwe zingakhale bwino kukana chithandizo ndi mankhwalawa.
Chifukwa chake, ndikofunika kumwa mankhwalawa:
- Nthawi yokhala ndi pakati ya azimayi, komanso nthawi yomwe mayi amamuyamwa mwana
- kumwa kwambiri mowa;
- pakakhala zovuta za chiwindi;
- wodwala matenda ashuga;
- ndi mavuto pokodza, omwe amagwirizana ndi matenda a impso;
- pambuyo myocardial infaration;
- pakakhala mavuto ndi mtima;
- chododometsa kapena chochita pambuyo pake.
Munthawi zonsezi, ndibwino kukana chithandizo ndi mankhwalawa. Nthawi yomweyo, osagwiritsanso ntchito fanizo la mankhwalawa. Mavuto azinthu zomwe zimagwira mthupi pazomwe zili pamwambazi zimatha kuvulaza thanzi la munthu.
Inde, pali nthawi zambiri pamene mankhwala amathandizadi wodwala, koma palinso umboni kuti ungakhale wovulaza thanzi.
Makamaka, izi zimachitika m'mikhalidwe yomwe odwala samanyalanyaza malangizo a dokotala ndikuyamba kuthandizidwa pawokha.
Malangizo ogwiritsira ntchito mankhwalawa
Kuthandizira kusintha shuga m'thupi la wodwalayo, zotulukazo zimachitika pamene wodwalayo amawona mosamalitsa mankhwala komanso mankhwalawa.
Chifukwa chakuti mankhwalawa ali ndi phula lalitali, ndikokwanira kumwa mapiritsi kamodzi patsiku. Ndipo ndibwino kuzichita usiku.
Ngati chithandizo chamankhwala chikuchitika molingana ndi malangizo ogwiritsira ntchito, ndiye kuti - nthawi yakumwa mankhwalawa imatha masiku 10 mpaka 20. Pambuyo pake, kupumula kwakanthawi kumapangidwa kukhala kwa miyezi iwiri, ndipo atatha mankhwalawa amapitilira mogwirizana ndi malangizo a dokotala.
Dongosolo la chithandizo cha munthu payekha likhonza kuperekedwa kwa wodwala aliyense, kutengera zomwe zimachitika mthupi lake komanso kupezeka kwake. Nthawi zambiri, mankhwalawa amathandizidwa ndi endocrinologist, yemwe amayambitsa kafukufuku wodwalayo pokhapokha atapereka njira yovomerezeka ya chithandizo.
Izi ndichifukwa choti aliyense wodwala matenda ashuga ali ndi zomwe ali ndi thupi. Mwanjira ina, m'chilengedwe mulibe chinthu chachiwiri chomwe chikhala ndi zofanana. Chifukwa chake, mankhwalawa amathandizidwa ndi dokotala ndipo amasiyana ndi malingaliro omwe dokotala amapatsa wodwala wina.
Pankhani imeneyi, sizovuta kunena kuti simuyenera kumwa nokha mankhwalawo. Choyamba muyenera kufunsa katswiri wa endocrinologist.
Mankhwalawa, monga analogues, omwe amaphatikizanso Metformin Long, amapatsidwa mankhwala awa:
- lembani matenda a shuga a 2 mwa odwala;
- Chithandizo cha matenda a shuga osagwiritsa ntchito mankhwala ena ochepetsa shuga (monotherapy);
- Kwa odwala omwe ali ndi zaka zosaposa 18, mankhwalawa amagwiritsidwa ntchito limodzi ndi mankhwala a insulin;
- pamene kudya ndi kuchita masewera olimbitsa thupi sizinathandize kuthana ndi shuga wambiri mthupi;
- omwe ali ndi mavuto a kunenepa kwambiri.
Kutengera ndi chidziwitso ichi, zikuwonekeratu kuti mankhwalawa amagwiritsidwa ntchito makamaka kwa anthu odwala matenda ashuga, omwe, motsutsana ndi matenda omwe amapezeka kale, ali ndi zovuta zodziwikiratu kuti ndi onenepa kwambiri.
Ndizofunikira kudziwa kuti malongosoledwe a mankhwala omwe amapezeka mu malangizowa amafotokoza mwatsatanetsatane momwe mankhwalawo amagwirira ntchito pa thupi komanso momwe amagwirira ntchito zofunika pamoyo
Wodwala aliyense ayenera kumwa mankhwala oti atulutsidwe kwa nthawi yayitali malinga ndi kuchuluka kwa mankhwalawa.
Kupenda kwamankhwala odwala ndi upangiri wachipatala
Mankhwala monga Glucofage Long 500 ndi mankhwala atsopano. Ndizoyenera kwa odwala omwe akufuna kuchita nthawi yayitali. Zimathandizira kuchepetsa bwino shuga ya wodwala. kusintha kukhathamira kwa shuga ndikupangitsa matenda a insulin kuphatikizika.
Koma awa ndi magawo akuluakulu a Glucophage Long 500 malangizo ogwiritsira ntchito akuwonetsanso kuti mankhwalawa amathandizira kwambiri ndi matenda a shuga komanso kunenepa kwambiri.
Koma, zowona, kuti amathandizadi wodwalayo, muyenera kufufuza kaye koyamba ndikuzindikira wodwalayo kuti adziwe. Izi zikuthandizira kutsimikizira njira yoyenera yothandizira, ndipo ngati ndi kotheka, kusankha mankhwala omwe adzamwe mankhwala limodzi. Ndikofunikanso kupatula njira zomwe zingachitike kwa wodwala wina.
Ndizodziwikiratu kuti masiku ano pali fanizo lazinthu zochizira izi. Koma muyenera kuwasankha pokhapokha ngati mukufunsidwa ndi dokotala, simungasankhe nokha kuti ndi mtundu uti wa mankhwala omwe ali ndi mankhwala omwe ali bwino ndikusintha njira zomwe zilipo kale.
Zowunikira momwe akuti "Glucophage, ndidapulumutsidwa kwamuyaya" kapena "ndakhala ndikumwa mankhwala okhawo kwa zaka zambiri ndipo kulemera kwanga kuli kwachibadwa", akhoza kukhala owona, koma pokhapokha ngati wodwalayo ali ndi mavuto ndi mayamwidwe a shuga, m'mawu ena, matenda ashuga. Tengani mankhwalawo kuti muchepetse thupi, popanda kuyang'aniridwa ndi adokotala ndikosatheka.
Odwala ambiri amasangalala ndi mtengo wa mankhwalawo. Tiyenera kudziwa kuti mtengo wamalondawo ndiwomveka, chifukwa chake, odwala ambiri amatha kugula malonda. Inde, pali zofananira za mankhwalawa, ndi adokotala okha omwe amayenera kuwalimbikitsa. Simuyenera kutenga chiopsezo ndikusankha nokha kapena njira ina, ndibwino kudalira katswiri.
Machitidwe a pharmacological a Glucophage akufotokozedwa mu kanema munkhaniyi.
