Pofika nthawi yomwe amupeza, odwala omwe ali ndi matenda amtundu woyamba, shuga wamagazi nthawi zambiri amakhala wokwera kwambiri. Chifukwa chake, amakumana ndi zizindikiro zotsatirazi: kuchepa thupi kosafunikira, ludzu losatha, komanso kukodza pafupipafupi. Zizindikirozi zimayamba kukhala zosavuta, kapena kuzimiririka, wodwalayo akangoyamba kulandira jakisoni wa insulin. Werengani momwe mungapangire insulin kuwombera mopweteka. Pambuyo pake, patatha milungu ingapo ya matenda a shuga ndi insulin, mwa odwala ambiri kufunika kwa insulin kumachepetsedwa, nthawi zina pafupifupi mpaka kumakhala zero.
Shuga wamagazi amakhalabe wabwinobwino, ngakhale mutasiya jakisoni. Zikuwoneka kuti matenda ashuga achiritsidwa. Nyengo iyi imatchedwa "phwando la tchuthi". Imatha kukhala milungu ingapo, miyezi, komanso mwa odwala ena chaka chathunthu. Ngati matenda a shuga 1 amathandizidwa ndi njira zachikhalidwe, ndiye kuti, “muzidya zakudya zabwino” ndiye kuti chisomo chaukwati ”chimatha. Izi sizichitika pakatha chaka chimodzi, ndipo nthawi zambiri pambuyo pa miyezi 1-2. Ndipo "kulumpha" kwakukulu mu shuga m'magazi kuchokera kumtunda kwambiri mpaka kutsika kwakukulu.
Dr. Bernstein akutsimikizira kuti "tchuthi" chitha kutalikirana kwa nthawi yayitali, pafupifupi kwa moyo wonse, ngati mtundu 1 wa matenda ashuga udwala. Izi zikutanthauza kuti azisunga chakudya chamagulu pang'ono komanso kubaya jekeseni wa insulin yocheperako.
Kodi nchifukwa chiyani nthawi ya "tchuthi" ya mtundu woyamba wa shuga imayamba ndipo bwanji imatha? Palibe malingaliro ovomerezeka pakati pa madokotala ndi asayansi pankhani iyi, koma pali malingaliro oyenera.
Malingaliro ofotokoza zaukwati wa mtundu woyamba wa matenda ashuga
Mwa munthu wathanzi, kapamba amunthu amakhala ndi maselo ambiri a beta omwe amapanga insulin kuposa momwe amafunikira kuti akhale ndi shuga wabwinobwino. Ngati shuga wamagazi amasungidwa, ndiye kuti izi zikutanthauza kuti pafupifupi 80% ya ma cell a beta amwalira kale. Kumayambiriro kwa matenda ashuga amtundu woyamba, maselo a beta omwe atsala amayamba kufooka chifukwa cha kuwopsa kwa shuga m'magazi. Izi zimatchedwa kawopsedwe wa glucose. Pambuyo pa kuyamba kwa matenda a shuga ndi jakisoni wa insulin, maselo a beta awa amalandira "kupumula", chifukwa komwe amabwezeretsa kupanga insulin. Koma amayenera kugwira ntchito molimbika kasanu kuposa momwe zimakhalira nthawi yayitali kuti athe kupereka insulin.
Ngati mumadya zakudya zamafuta ambiri, ndiye kuti pakhale shuga wa magazi wambiri, womwe sangathe kuphimba jakisoni wa insulin komanso kupanga pang'ono kwa insulin yanu. Zatsimikiziridwa kale kuti shuga yowonjezereka yam'magazi imapha maselo a beta. Chakudya chomwe chili ndi zakudya zamafuta ochulukirapo, shuga wamagazi amakwera kwambiri. Zoterezi zilizonse zimakhala ndi zovulaza. Pang'onopang'ono, izi zimadziunjikira, ndipo ma cell otsala a beta pamapeto pake "amatheratu".
Choyamba, maselo a pancreatic beta a mtundu 1 a shuga amafa chifukwa cha chitetezo cha mthupi. Cholinga cha nkhondoyi si cell yonse ya beta, koma mapuloteni ochepa chabe. Imodzi mwa mapuloteni awa ndi insulin. Puloteni ina yomwe imalimbana ndi autoimmune imapezeka m'miyala yomwe ili mkati mwa maselo a beta momwe insulin imasungidwira "mosungira". Mtundu woyamba wa matenda ashuga utayamba, palibenso "ma" bubul "ena ogulitsa insulin. Chifukwa insulin yonse yomwe imapangidwa imadyedwa nthawi yomweyo. Chifukwa chake, kuchuluka kwa kuukira kwa autoimmune kumachepetsedwa. Malingaliro awa ochokera ku “tchuthi cha chikwati” sanatsimikiziridwebe.
Momwe mungakhalire?
Ngati mumachiza matenda amtundu woyamba wa shuga, ndiye kuti nthawi ya “tchuthi” ikhoza kupitilizidwa. Zoyenera, moyo. Kuti muchite izi, muyenera kuthandizira kapamba wanu, yesani kuchepetsa katundu pazomweyo. Izi zikuthandizira chakudya chamafuta ochepa, komanso jakisoni ang'onoang'ono, omwe amakhala ndi insulin.
Ambiri mwa anthu odwala matenda ashuga, kumayambiriro kwa chikwati, amasuka ndikumenya gawo lanu. Koma izi siziyenera kuchitika. Muyezetsetse magazi anu kangapo patsiku ndi kubaya insulin pang'ono kuti apatsenso kapamba.
Palinso chifukwa china choyesera chosungira maselo anu a beta amoyo. Ngati mankhwala atsopano a shuga, monga beta-cell cloning, atawonekera, mudzakhala woyamba kusankha kugwiritsa ntchito mankhwalawa.