Zotsatira zakugwiritsira ntchito Neurobion mu shuga

Neurobion ndi mankhwala amakono a multivitamin. Zotsatira zochizira zamankhwala zimachitika chifukwa cha thiamine, pyridoxine ndi cyanocobalamin. Madokotala nthawi zambiri amapereka mankhwala ochizira matenda amanjenje.

ATX

A11DB (Mavitamini B1, B6 ndi B12).

Neurobion ndi mankhwala amakono a multivitamin.

Kutulutsa mafomu ndi kapangidwe kake

Pamsika wamankhwala m'dziko lathu, mankhwalawa atha kugulidwa pamapiritsi ndi ma ampoules a 3 ml.

Mapiritsi

Mapiritsiwo ndi biconvex, wokutidwa ndi chipolopolo choyera choyera pamwamba. The mankhwala zikuchokera mankhwala amaperekedwa.

Mapiritsiwo ndi biconvex, wokutidwa ndi chipolopolo choyera choyera pamwamba.

Njira Zothetsera

Mankhwala ogwiritsa ntchito ngati kholo ndi madzi ofiira owonekera.

Zotsatira za pharmacological

Mavitamini a gulu B, ophatikizidwa ndi kapangidwe ka mankhwalawa, othandizira njira za redox, amawongolera kagayidwe ka lipids, mapuloteni ndi chakudya. Mankhwalawa, mosiyana ndi mafuta osungunuka a mafuta, samayikidwa m'thupi la munthu, chifukwa chake, amayenera kukhala pafupipafupi komanso mokwanira kuti alowe mthupi ndi chakudya kapena monga gawo lamavitamini. Ngakhale kuchepa kwakanthawi kochepa mphamvu kumachepetsa ntchito zama enzyme, zomwe zimalepheretsa kagayidwe kazakudya komanso kuchepetsa chitetezo.

Mavitamini a gulu B, ophatikizidwa ndi kapangidwe ka mankhwalawa, othandizira njira za redox.

Pharmacokinetics

Ndi kuchepa kwa thiamine m'thupi, njira yosinthira kwa pyruvate kukhala yodziyimira acetate acid (acetyl-CoA) imasokonekera. Zotsatira zake, ma keto acid (α-ketoglutarate, puruvate) amadziunjikira m'magazi komanso zimakhala ndi ziwalo, zomwe zimatsogolera "acidization" ya thupi. Acidosis imayamba pakapita nthawi.

Bioactive metabolite ya vitamini B1 - thiamine pyrophosphate, imagwira ntchito osakhala mapuloteni a decarboxylases a pyruvic ndi α-ketoglutaric acids (i.e., amatenga nawo mbali mu catalysis ya carbohydrate oxidation). Acetyl-CoA imaphatikizidwa kuzungulira kwa Krebs ndipo imaphatikizidwa ndi madzi ndi mpweya woipa, pomwe imakhala mphamvu. Nthawi yomweyo, thiamine hydrochloride imakhudzidwa ndikupanga mafuta acids ndi cholesterol, imayendetsa njira yosinthira michere kukhala mafuta.

Mukapereka pakamwa, theka la moyo wa vitamini B1 ndi pafupifupi maola 4.

Mukapereka pakamwa, theka la moyo wa vitamini B1 ndi pafupifupi maola 4. Mu chiwindi, thiamine imapangidwa phosphorylated ndikusinthidwa kukhala thiamine pyrophosphate. Thupi la munthu wamkulu limakhala ndi pafupifupi 30 mg ya vitamini B1. Poganizira kwambiri kagayidwe, kamatuluka m'thupi mkati mwa masiku 5-7.

Pyridoxine ndi gawo lophatikizika la coenzymes (pyridoxalphosphate, pyridoxamine phosphate). Ndi kuchepa kwa vitamini B6, kusinthana kwa amino acid, ma peptides ndi mapuloteni amasokoneza. M'magazi, kuchuluka kwa maselo ofiira a m'magazi kumachepa, hemostasis imasokonekera, kuchuluka kwa mapuloteni a seramu amasintha. M'madera otukuka kwambiri, kuchepa kwa mavitamini osungunuka am'madzi kumabweretsa kusintha kwa khungu. Thupi limakhala ndi pafupifupi 150 mg ya pyridoxine.

Ndi kuchepa kwa vitamini B6, kusinthana kwa amino acid, ma peptides ndi mapuloteni amasokoneza.

Pyridoxalphosphate imathandizira pakupanga ma neurotransmitters ndi mahomoni (acetylcholine, serotonin, taurine, histamine, tryptamine, adrenaline, norepinephrine). Pyridoxine imathandiziranso kupanga biosynthesis ya sphingolipids, zomwe zimapangidwa ndi ma myelin sheaths a minyewa yamitsempha.

Cyanocobalamin ndi mavitamini okhala ndi zitsulo zomwe zimathandizira kupangidwa kwa maselo ofiira am'magazi, zimayambitsa michere ya chiwindi yomwe imapangitsa kuti carotenoids isinthe.

Vitamini B12 imafunikira pakupanga kwa deoxyribonucleic acid, homocysteine, adrenaline, methionine, norepinephrine, choline ndi creatine. Mapangidwe a cyanocobalamin akuphatikiza cobalt, gulu la nucleotide ndi radyan cyanide. Vitamini B12 imayikidwa makamaka m'chiwindi.

Vitamini B12 ndiyofunikira pakapangidwe ka deoxyribonucleic acid.

Zizindikiro zogwiritsidwa ntchito

Mankhwala ndi ntchito mankhwala otsatirawa pathologies:

• radiculopathy;
• thoracalgia;
• matenda a msana (spondylarthrosis, osteochondrosis, spondylosis);
• matenda a neuropathic;
• herpes zoster;
• trigeminal neuralgia;
• lumbar syndrome;
• Chiwopsezo cha Bell;
• kuchuluka.

Contraindication

Mankhwalawa ali ndi zotsutsana zingapo pakusankhidwa kwake:

• thromboembolism;
• zaka za ana;
• erythremia;
• Hypersensitivity;
• zilonda zam'mimba;
• ziwengo

Mankhwala amapatsidwa thoracalgia.

Matenda a Neuropathic ndi chifukwa chokhazikitsidwa ndi mankhwalawa.

Ndi herpes zoster, Neurobion ndiyabwino kwambiri.

Trigeminal neuralgia ndimatenda omwe minyewa yam'mimba imatengedwa.

Neurobion adalembedwa kuti Bell Ruole.

Ndi plexopathy, neurobion imatengedwa.

Neurobion imapangidwira radiculopathy.

Momwe angatenge

Pofuna kupewa kubwereranso kwa matendawa, mankhwalawa amayikidwa piritsi, 1 kapisozi katatu patsiku. Mukamamwa mapiritsi, muyenera kumwa ndi madzi ambiri. Kutalika kwa nthawi ya mankhwala kutsimikiza ndi dokotala.

Mankhwalawa mu ampoules amakhazikikanso kuti apangike. Musanachotse zizindikiro zazikulu za matendawa, tikulimbikitsidwa kupaka jekeseni 1 nthawi patsiku. Pambuyo pomva bwino, jakisoni amachitika kamodzi pa sabata kwa masabata awiri.

Ndi matenda ashuga

Chida pamwambapa ndi chabwino pochiza ululu wa neuropathic odwala omwe ali ndi matenda ashuga a polyneuropathy. Zinapezeka kuti mankhwalawa amachepetsa kuuma kwa zovuta paresthesia, amachepetsa kukhudzika kwa khungu, amathandizanso kupweteka.

Pofuna kupewa kubwereranso kwa matendawa, mankhwalawa amayikidwa piritsi, 1 kapisozi katatu patsiku.

Zotsatira zoyipa

Mankhwalawa amaloledwa ndi odwala ambiri. Komabe, nthawi zina, kuwonetsa kwa zovuta zomwe zimagawika m'magulu ndizotheka.

Matumbo

• kumeza movutikira;
• kusanza
• zotupa m'matumbo;
• kupweteka pamimba;
• nseru
• chisangalalo;
• kutsegula m'mimba

Kuchokera ku chitetezo chamthupi

• Edema ya Quincke;
• dermatitis;
• chikanga
• anaphylactoid zimachitika.

Matupi omaliza

• zotupa
• kuyabwa
• hyperemia;
• thukuta kwambiri;
• kupweteka
• ziphuphu
• urticaria;
• necrosis pa jekeseni malo.

Mukamamwa mankhwala angayambitse mseru, kusanza.

Chimodzi mwazotsatira zoyipa za kutenga Neurobion ndi kutsekula m'mimba.

Kutupa, kuyabwa, dermatitis - mavuto obwera chifukwa cha kumwa mankhwalawa.

Mukamatenga Neurobion, thukuta kwambiri limatha kuchitika.

Pa chithandizo ndi Neurobion, kupezeka kwa kugunda kwamtima, kupweteka kwamtima kumatha kuchitika.

Mukamamwa mankhwalawa, chizungulire amatha.

Kukhumudwa, migraine - mavuto obwera chifukwa chotenga Nerobion.

Mtima wamtima

• kukoka kwamtima;
• kupweteka pachifuwa.

Machitidwe amanjenje

• Hyper irritability;
• migraine
• sensop neuropathy;
• paresthesia;
• Kukhumudwa
• chizungulire.

Malangizo apadera

Mankhwalawa sanapangidwe kuti apangidwe. Komanso, mankhwalawa sangathe kugwiritsidwa ntchito mwa odwala omwe ali ndi vuto lalikulu la mtima. Mosamala kwambiri, mankhwalawa amayenera kuperekedwa kwa anthu omwe ali ndi vuto loopsa la neoplasms.

Mankhwalawa sanapangidwe kuti apangidwe.

Zokhudza mphamvu pakuwongolera njira

Mankhwalawa sasokoneza munthu pakuyendetsa magalimoto komanso magwiridwe antchito.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Pa kubereka mwana, mankhwalawa amatha kugwiritsidwa ntchito pokhapokha ngati pali umboni wowoneka wa mavitamini B1, B6 ndi B12 m'thupi la mayi woyembekezera. Mphamvu ya mankhwala pa mimba, mwana asanabadwe ndi pambuyo pake.

Dokotala amayenera kudziwa kuyenera kwa kupereka mankhwala panthawi yomwe ali ndi pakati, kudziwa mgwirizano womwe ulipo pakati paubwino ndi chiwopsezo.

Mavitamini omwe amapanga mankhwalawa amachotsedwa ndi chinsinsi cha tiziwalo ta mammary, komabe, chiopsezo cha hypervitaminosis mwa makanda sichinakhazikitsidwe. Kulandila kwa pyridoxine mu milingo yayikulu (> 600 mg patsiku) kungayambitse hypo- kapena agalactia.

Pa kubereka mwana, mankhwalawa amatha kugwiritsidwa ntchito pokhapokha ngati pali umboni wowoneka wa mavitamini B1, B6 ndi B12 m'thupi la mayi woyembekezera.

Kuikidwa kwa neurobion kwa ana

Ana ochepera zaka 15 ali osavomerezeka kuti apereke mankhwala.

Gwiritsani ntchito mu ukalamba

Zambiri pakugwiritsa ntchito mankhwalawa okalamba ndi senile sizikupezeka.

Bongo

M'mabuku apadera, zovuta za mankhwala osokoneza bongo a mankhwala ambiri zimafotokozedwa. Odwala amadandaula chifukwa chodwaladwala, kupweteka minofu, mafupa, nseru komanso kutopa kwambiri. Ngati mukupeza zizindikiro zomwe zili pamwambapa, mankhwalawa ayenera kuthetsedwa ndikuonana ndi dokotala. Adziwa chomwe chimayambitsa mavutowo, kupereka mankhwala othandizira.

Vitamini B1

Pambuyo poyambitsa thiamine muyezo wopitilira nthawi yopitilira 100, Hypercoagulation, kusokonezeka kwa purine metabolism, curariform ganglioblocking zotsatira zomwe zimayambitsa kutsika kwa kukhudzika kwa mitsempha.

Kumva kusayenda bwino, kufooka kwathunthu ndi chizindikiro cha kuchuluka kwa mankhwalawa.

Vitamini B6

Pambuyo polandila kwa nthawi yayitali (kupitirira miyezi isanu ndi umodzi) ya pyridoxine pa mlingo woposa 50 mg / tsiku, chiwonetsero cha zotsatira za neurotoxic (hypochromasia, seborrheic eczema, khunyu, neuropathy ndi ataxia) ndizotheka.

Vitamini B12

Ngati bongo, thupi lawo siligwirizana, migraine, kusowa tulo, ziphuphu, matenda oopsa, kuyabwa, kukokana kwa m'munsi malekezero, kutsegula m'mimba, kuchepa magazi ndi anaphylactic.

Kuchita ndi mankhwala ena

Malangizo ogwiritsira ntchito akuwonetsa kuti mankhwala ena sagwirizana ndi mankhwalawa. Nthawi zina, kutsata komweku kumabweretsa kufooka kwa chithandizo chamankhwala kapena kuwonjezeka kwa chiwonetsero chotsatira:

1. Thiamine imawonongedwa chifukwa cha kulumikizana ndi mankhwala omwe ali ndi sulfite (potaziyamu metabisulfite, potaziyamu), sodium hydrosulfite, sodium sulfite, etc.).
2. Kugwiritsira ntchito pamodzi kwa cycloserine ndi D-penicillamine kumawonjezera kufunikira kwa pyridoxine.
3. Mankhwalawa sayenera kusakanikirana ndi mankhwala ena omwe ali mu syringe yomweyo.
4. Makonzedwe a okodzetsa amatsogolera kutsika kwa vitamini B1 m'magazi ndipo imathandizira kwambiri impso yake.

Mankhwalawa sayenera kusakanikirana ndi mankhwala ena omwe ali mu syringe yomweyo.

Wodwalayo ayenera kudziwitsa adotolo za mankhwala omwe akumwa. Dokotala pankhaniyi amasintha dongosolo la mankhwalawo, potero amachepetsa kuyambitsa mavuto.

Analogi

Ngati ndi kotheka, mankhwalawa atha kusinthidwa ndi njira monga:

• Neurolek;
• Kombilipen;
• Milgamma
• Vitaxone;
• Neuromax;
• Zosasangalatsa;
• Neuromultivitis;
• Esmin;
• Neurobeks-Teva;
• Selmevite;
• Dynamizan;
• Unigamm
• Kombilipen;
• Centrum;
• Pantovigar;
• Farmaton
• Ginton;
• Nerviplex;
• Aktimunn;
• Berocca kuphatikiza;
• Encaps;
• Detoxyl
• Pregnakea;
• Neovitam;
• mavitamini B1, B12, B6;
• Megadine;
• Neurobeks-Forte.

Neuromax ndi analogue osauka a Neurobion.

M'malo mwa Neurobion, mutha kutenga Revalid.

Neuromultivitis ndi analogue ya Neurobion.

Pantovigar ali ndi mankhwala ofanana ndi Neurobion.

Combiplane imawerengedwa kuti ndi analogue ya Neurobion.

Milgamm imakhala ndi chinthu chofanana ndi Neurobion.

Wopanga

Wopanga wamkulu wa mankhwalawo ndi Merck KGaA (Germany).

Kupita kwina mankhwala

Mankhwala, mankhwalawa amaperekedwa ndi mankhwala, koma sikuti ndi mankhwala omwe mumalandira.

Mtengo wa Neurobion

Mtengo wa mankhwalawa ku Russia umasiyanasiyana pamtengo wamtundu kuchokera ku 220 mpaka 340 rubles. Ku Ukraine - 55-70 UAH. kunyamula.

Kusungidwa kwa mankhwala Neurobion

Sungani mankhwalawo pamalo amdima komanso ozizira.

Tsiku lotha ntchito

Zaka zitatu

Ndemanga za madotolo ndi odwala za Neurobion

Svetlana wazaka 39, ku Kiev: "Ndakhala ndimavuto a msana kuyambira ndili ndi zaka 18. Osteochondrosis adapezeka. Dokotala adapereka ma jakisoni jakisoni. Mankhwalawa adalowetsa intramuscularly, 1 ampoule patsiku. Pambuyo pa maphunziro a milungu iwiri, thanzi langa lidawonjezeka komanso kupweteka kudera lumbar. Pazolinga za prophylactic, ndimagwiritsa ntchito mankhwalawa mawonekedwe a piritsi.

Andrei wazaka 37, Astrakhan: "Posachedwa iwo adayamba kuda nkhawa ndi kuyabwa kwambiri komanso kupweteka m'malo a minofu. Atayikidwa ndi adotolo, adazindikira kuti ndili ndi radicular neuritis. Dokotala wamatsenga adayambitsa jakisoni wa Neurobion. Zovuta zonsezo zidachoka pomwepo.Kwa masiku anayi mankhwalawa adalandiridwa tsiku lililonse. 1 wokwanira pa sabata anali atalembedwa. Ndine wokhutira ndi zotsatira za mankhwalawo. "

Sabina wazaka 30, ku Moscow: "Ndakhala ndikugwiritsa ntchito mavitamini a lumbar neuralgia kwa nthawi yayitali. Pakapita nthawi, iwo anasiya kuthandizira. Nditapita kwa dotolo, adavulaza Neurobion. Patatha masiku ochepa ndatsitsimuka. Nditachira, ndidzagwiranso ntchito ngati prophylactic. mankhwala ngati mapiritsi. "

Artyom wazaka 25, Bryansk: "Adagwiritsa ntchito njira yovomerezeka ya Vitamini pochiza matenda a neuro-brachial syndrome. Amapereka jakisoni tsiku lililonse kwa masiku 5. Mankhwalawa amathandizanso kupweteka komanso kubwezeretsa thupi ndi kuchuluka kwa mavitamini. Pambuyo pa maphunziro a milungu itatu, dotolo adapereka mapiritsi kuti agwiritsidwe ntchito mosalekeza. amagwiritsidwa ntchito ngati mankhwala ochiritsira kuti musadzabwerenso. "