Kuwongolera ndi kuchiza matenda a shuga
Masiku ano, pali anthu pafupifupi 357 miliyoni padziko lonse lapansi omwe ali ndi matenda ashuga. Malinga ndi kuyerekezera, podzafika chaka cha 2035 kuchuluka kwa anthu odwala matendawa kudzafika anthu 592 miliyoni.
Zonsezi zimatenga nthawi yambiri, kuphatikiza apo, njirayi imapweteka ndipo si yolondola nthawi zonse. Kukhazikitsa mlingo wa insulin mopitirira muyeso kumatha kubweretsa zotsatirapo zoipa monga khungu, chikomokere, kudzichepa kwa malekezero ngakhale imfa.Njira zolondola zowonjezereka zoperekera mankhwala kulowa m'magazi zimakhazikitsidwa ndi insulin pansi pa khungu pogwiritsa ntchito masingano, omwe amasinthidwa nthawi ndi nthawi pambuyo masiku ochepa, zomwe zimayambitsa zovuta kwa wodwalayo.
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Zigamba za insulin - zosavuta, zosavuta, zotetezeka
"Chigoba" ndi kachidutswa kakang'ono ka masikono, komwe kali ndi ma micule ambiri, m'mimba mwake sikuposa kukula kwa eyelash ya munthu. Ma Microneedles ali ndi malo ena osungira omwe amasunga insulin ndi ma enzyme omwe amatha kupeza mamolekyu a magazi m'magazi. Masewera a shuga akakwera, chizindikiro chimatumizidwa kuchokera ku ma enzymes ndipo kuchuluka kwa insulin kumayikidwa pansi pakhungu.
- hyaluronic acid
- 2-nitroimidazole.
Mwa kuwaphatikiza, asayansi adalandira molekyulu kuchokera kunja yomwe simalumikizana ndi madzi, koma mkati mwake imapanga mgwirizano nawo. Ma Enzymes omwe amayang'anira kuchuluka kwa glucose ndi insulin adayikidwa mu vial iliyonse - chosungira.
Gluconic acid, yowononga mpweya wonse, imatsogolera molekyuluyo kuti isafe ndi mpweya. Chifukwa cha kusowa kwa mpweya, molekyuluyo imasweka, ndikutulutsa insulin m'magazi.
Pambuyo pakupanga Mbale zapadera za insulin - storages, asayansi adakumana ndi funso kuti apange njira yowayang'anira. M'malo mwakugwiritsa ntchito singano zazikulu ndi catheters, zomwe ndizovuta kugwiritsa ntchito tsiku ndi tsiku kwa odwala, asayansi apanga singano zazing'ono kwambiri pakuziyika pamtunda wa silicon.
Ma Microneedles adapangidwa kuchokera ku hyaluronic acid womwewo, womwe ndi gawo la mabulosi, kokha ndi mawonekedwe olimba kotero kuti singano amatha kubaya khungu la munthu. Katswiri wanzeru “akafika pakhungu la wodwalayo, maikolofoniyo imalowa m'matumbo oyandikira kwambiri pakhungu popanda kumuyambitsa wodwalayo.
Chigoba chomwe chidapangidwa chimakhala ndi zabwino zingapo pamachitidwe omwe amapangira insulin - ndi yosavuta kugwiritsa ntchito, yopanda poizoni, yopangidwa ndi zinthu zosagwirizana ndi zinthu zambiri.
Kuphatikiza apo, asayansi adadziyesetsa kukhala ndi "patch mwanzeru" wopanga aliyense payekhapayekha, poganizira kulemera kwake komanso kulolera kwa insulin.
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Mayeso oyamba
Patch yatsopano idayesedwa bwino mu mbewa ndi matenda a shuga 1. Zotsatira za phunziroli zinali kuchepa kwa shuga m'magazi kwa maola 9. Poyeserera, gulu limodzi la mbewa linalandira jakisoni wodziwika bwino, gulu lachiwiri linachizidwa ndi "chigamba chanzeru".
Pamapeto pa kuyeserako, zidapezeka kuti m'gulu loyambirira la mbewa, shuga m'magazi pambuyo pa kayendetsedwe ka insulin adatsika kwambiri, koma kenako adadzuka kokhazikika. Gulu lachiwiri, kutsika kwa shuga kunawoneka kukhala kwabwinobwino mkati mwa theka la ola pambuyo pa kugwiritsa ntchito "chigamba", chotsalira chimodzimodzi kwa maola ena 9.
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