Chlorhexidine ndi wothandizira kuchokera pagulu la antiseptics kuti azigwiritsa ntchito zakunja munjira zosiyanasiyana zamankhwala, cosmetology, kuphera tizilombo toyambitsa matenda, kuyeretsa nyumba.
ATX
D08AC02 - dermatological antiseptic ndi mankhwala opha gulu la Biguanides ndi maini - Chlorhexidinum. INN - Chlorhexidine.
Chlorhexidine ndi wothandizira kuchokera pagulu la antiseptics kuti azigwiritsa ntchito zakunja munjira zosiyanasiyana zamankhwala, cosmetology, kuphera tizilombo toyambitsa matenda, kuyeretsa nyumba.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka m'mitundu ingapo ya mitundu, yomwe imasiyana mosiyanasiyana ndi zomwe zimapezeka.
Njira Zothetsera
Zomwe zimagwira ndi chlorhexidine bigluconate. Choikiracho chimayikidwa m'mabotolo apulasitiki osakhala ndi chopopera kapena magalasi. 100 ml ya malonda ali ndi 0,05% (0.25 ml) yankho la chinthu chomwe chikugwira ntchito. Chidebe chilichonse chimayikidwa m'bokosi lamanzere.
Mumabotolo akuluakulu a 100 ml ndi 0,5 l, yankho la 20% limapangidwa.
Utsi
Spray imapezeka m'mabotolo apulasitiki a 45 ml. Mukupanga ndi kugwiritsidwa ntchito kwa zinthu zogwira ntchito, sizisiyana ndi yankho la 0,05%. Tankiyo imakhala ndi pampu yokumba yopopera madzi.
Makandulo aikidwa 5 ma PC. m'matuza. Makatoni okhala ndi matuza 2 (Na. 10).
Makandulo
Ma suppositories anyama:
- 20% (16 mg) chlorhexidine njira yayikulu ya gluluate;
- macrogol (polyethylene glycol) 1500 ndi 400 ngati filler.
Makandulo okhala ndi mawonekedwe Kusunthika kwa pamwamba ndikololedwa. Makandulo aikidwa 5 ma PC. m'matuza. Makatoni okhala ndi matuza 2 (Na. 10). Ma suppositories amapezekanso ndi zinthu zotsika - 8 g. Ndi mtundu wa ana wa supplements a vaginal.
Gel
Gawo la chlorhexidine limaphatikizapo:
- 20% yankho (5.0 mg) ya chinthu chogwira;
- glycerin;
- natrozole okhazikika;
- delta lactone;
- zoteteza E218;
- madzi osungunuka.
Chogulitsachi ndi geti yowonekera popanda mtundu, mawonekedwe osasinthika, osanunkha kanthu, osanunkhira bwino. Gelali imayikidwa mu chubu cha 50 g lamoni
Mafuta, kuwonjezera pa gawo lalikulu la yankho la 0,05% ya chlorhexidine bicarbonate, lili ndi zinthu zina zothandiza komanso mankhwala - zinc, hydrocortisone, lidocaine.
Mafuta
Mafuta, kuwonjezera pa gawo lalikulu la yankho la 0,05% ya chlorhexidine bicarbonate, lili ndi zinthu zina zothandiza komanso mankhwala - zinc, hydrocortisone, lidocaine.
Njira yamachitidwe
Amalumikizana ndi magulu a phosphorous a lipids mu membrane wa cell: kukhulupirika kwake kumaphwanyidwa, zomwe zili mkati mwa cell zimasungidwa mu mawonekedwe abwino a mpweya (mpweya wabwino), potaziyamu ndi phosphorous zimatayika. Selo la pathogen limafa.
Zotsatira zamankhwala a chlorhexidine omwe ali ndi matenda oyamba ndi fungus, kufalikira kwa kufalikira kwa ma fungal kumachepa.
Kutengera ndende, yankho limakhala ndi zotsatirapo zosiyanasiyana za tizilombo:
- amapha -> 0,01% - "mamolekyulu" a chinthu "ophatikizidwa" mu lipid wosanjikiza ndi kuphatikizanso kwa mawonekedwe ake, komanso kunyamula kwa denser, komwe kumaphwanya kuchuluka kwa membrane;
- Imachepetsa kukula ndi kubereka - <0.01% - imayambitsa "kuchepa" kwamamolekyu mafuta ndi ma mamolekyulu a chlorhexidine, kuchuluka kwa kuchuluka ndi kuchuluka kwa cell hydration.
Mankhwala osokoneza bongo amagwira ntchito motsutsana ndi bakiteriya wa gramu-gramu komanso gram-negative (kupatula bacillus wa Koch), protozoa (Trichomonas), HSV. Ndi kubwera kwa mabakiteriya osamva maantibayotiki, kufunikira kwa chithandizo cham'deralo kumawonjezeka. Kugwiritsa ntchito njira zogwiritsirira ntchito antiseptic kumachepetsa chiopsezo cha mitundu yamaaselo ofala.
Zotsatira za mankhwalawa chifukwa cha matenda oyamba ndi fungus ndi Chlorhexidine, malo ogawa mafinya amatsika, omwe amachititsa kuti mankhwalawa azigwira bwino ntchito molingana ndi bowa wa mtundu wa Candida ndi othandizira ena opatsirana omwe amayambitsa matenda a fungus a pakhungu, misomali, khungu. Katundu wa fungicidal amawonekera ngakhale mu yankho la 0,05%.
Mankhwalawa amaphwanya kuthekera kwa tizilombo tating'onoting'ono.
Chlorhexidine wapezeka kuti ndi wothandiza kwambiri pokana ndi methicillin-staphylococci yomwe imayambitsa matenda amkati.
Ndinapezanso zambiri pazakuwonongeka kwama microflora ambiri
- Mafangasi onga yisiti Malassezia spp., Omwe umayambitsa matenda a khungu - seborrhea, lichen, dermatitis, hyperkeratosis, psoriasis, komanso kuchepa kwa chitetezo chokwanira - matenda a systemic.
- Pseudomonas aeruginosa Pseudomonas aeruginosa, wopezeka mu zilonda, mabala am'mimba, cystitis, enteritis. Kuvuta kwa mankhwala othandizira antibayotiki kumachitika chifukwa cha kupangika kwa zopsinjika zosagwira.
Mukamawerengera za Chlorhexidine pa tizilombo tating'onoting'ono ta mucosa tam'kamwa, zimapezeka kuti zimagwira ntchito kwambiri ngakhale pakukanika kwambiri (0,05%), koma zikuwonetsa zotsatira zabwino mu ma gel, chifukwa, mosiyana ndi yankho, sikuchepetsa kuthamanga kwa kukonza (kuchira).
Mankhwalawa samangokhala ndi tizilombo toyambitsa matenda, amakhudza kayendedwe ka biofilm - gulu lolinganizidwa la tizilombo tating'onoting'ono tokhala pamaselo a maselo, ma organic olimba komanso mawonekedwe. Mankhwalawa amaphwanya kuthekera kwa tizilombo tating'onoting'ono.
Chlorhexidine amachita ngati yisiti ngati fungus Malassezia spp., Amapangitsa kuchepa kwa chitetezo chokwanira.
Pharmacokinetics
Mankhwalawa amapangira mankhwala am'deralo. Ikagwiritsidwa ntchito pang'onopang'ono pa khungu, simalowa mu kayendedwe ka kayendedwe kazinthu, malinga ngati minofu yokhazikika sikowonongeka. Njira yothetsera vutoli imakhala yokhazikika komanso pambuyo povomerezeka kwa nthawi yayitali ikupitirirabe. Imakhalabe yothandiza, ngakhale ndiyocheperako, pakakhala madzi achilengedwe.
Ikamamwa, simayamwa m'matumbo lumen. Gawo lalikulu limapukutidwa ndipo 1% yokha - ndi mkodzo.
Zizindikiro zogwiritsidwa ntchito
Mankhwala, mankhwalawa amagwiritsidwa ntchito pochizira ndi prophylactic mogwirizana ndi tizilombo toyambitsa matenda omwe amatengera zotsatira za chlorhexidine bicarbonate:
- M'mano a caries, gingivitis, periodontitis, stomatitis, aphthae, poyeretsa ndikukhalabe aukhondo pakamwa. Amachotsa fungo losasangalatsa, kutuluka magazi ndi kutupa kwa mano, kumalimbitsa mano, kumathandizira kuchepetsa caries, pambuyo panjira zowononga, chifukwa cha kupha tizilombo ta mano.
- Mu otolaryngology - matenda a oropharynx (tonsillitis, tonsillitis, pharyngitis), inhalation mankhwalawa bronchitis, chibayo, laryngitis, tracheitis. Pakulowetsa m'mphuno ndi m'makutu, mankhwalawa sagwiritsidwa ntchito.
- Mu gynecology ndi obstetrics - omwe ali ndi vulvitis, colpitis, vaginosis, candidiasis (thrush), STD. Monga kupewa kwa matenda obwera pambuyo pake, munthawi ya matenda, mutagonana osagwiritsa ntchito kondomu.
- Mu urology - ndi urethritis, urethrostatitis, kukonzekera kupezeka kwa chikhodzodzo - cystoscopy. Mankhwala amagwiritsidwa ntchito popanga catheters ophatikizidwa ndi chlorhexidine kunja ndi mkati.
- Mu dermatology ndi cosmetology - ndi furunculosis, ziphuphu, dermatosis, lichen, psoriasis, seborrhea.
- Mu opaleshoni - zochizira mabala am'mimba, zilonda zam'mimba, zithandizo za mankhwalawa, zochizira zowotcha, kupewa matenda osokoneza bongo ndi sepsis, mankhwalawa.
Contraindication
Osagwiritsa ntchito ndi:
- matanthauzidwe amatsenga;
- viral zotupa za khungu.
Chenjezo limalangizidwa kugwiritsa ntchito mankhwalawa mukadzakulitsa mu dongosolo la urogenital system.
Momwe mungagwiritsire ntchito chlorhexidine?
Njira yogwiritsira ntchito mankhwalawa zimatengera cholinga, mawonekedwe, zaka za wodwalayo,
Kusintha (%) | Kusankhidwa |
0,05 | Ngati kuphwanya umphumphu wa epermermis, mano, matenda a ENT, kupewa matenda opatsirana pogonana, chifukwa chogwiritsa ntchito, mukapukusa kudula ndi mbale. |
0,1 | Kuthana ndi suture, mano, mankhwala a ENT pathologies, ming'alu, masoka, matuza pakhungu. |
0,2 | Mukakonza mano, ku matenda a mano ndi kukodza, pokonzekera njira zodziwira matenda urogenital. |
0,5 | Mu mano, ndi matenda a ENT, kusamalira machitidwe a zodzikongoletsera - kulemba tattoo, kuboola; azichitira ziphuphu, ziphuphu. |
1,0 | Kuwongolera zida, kuyeretsa malo, mipando, zida, zosefera. |
Mowa umagwiritsidwa ntchito kupukutira zida, kupha tizilombo toyambitsa matenda. Njira zothetsera zakumwa zakakonzedwa kuchokera ku gawo limodzi la 20% yokhazikika komanso magawo 40 a mowa 70%.
Kupukusa, kuchiritsa mabala ndi kuwotcha, kugona ndikukhazikitsa mu urethra ndi chikhodzodzo, yankho lamadzimadzi la chofooka chofooka limagwiritsidwa ntchito.
Ma Vaginal suppositories amagwiritsidwa ntchito ngati matenda opatsirana pogonana komanso pochotsa njira yakubereka. Mutha kugwiritsa ntchito pa nthawi yonse ya kukomoka ndi mkwatibwi. Fomu ya ana imalembedwa kwa atsikana mpaka mwezi woyamba asanafike pochita opaleshoni ya gynecological pathologies, venvovaginitis.
Gel (0.5%) amagwiritsidwa ntchito pochiza kuvulala kwa khungu, mu cosmetology (ziphuphu zakumaso, ziphuphu, potsatira njira zodzikongoletsera). M'mazenera, mano amawaika pakamwa yapadera - chingamu chimadziwika ndi ntchito yake yayitali. Gelayo imagwiritsidwa ntchito kupaka mafuta a catheters, makondomu, kupanga filimu yoteteza pamanja.
Gel (0.5%) amagwiritsidwa ntchito pochiza kuvulala kwa khungu, mu cosmetology (ziphuphu zakumaso, ziphuphu, potsatira njira zodzikongoletsera).
Chithandizo chogwira ntchito cha mankhwalawo ndi gawo la mafuta, zotupa, zodzikongoletsera zam'maso, zopaka, mafuta, mafuta.
Momwe mungasungire ma rinsing?
Pakutsuka, gwiritsani ntchito 0,05 ndi 0,1% yankho lamadzimadzi a chlorhexidine. Kuti akonze zomwe zimafunikira, 200 ml ya madzi amatengedwa kuchokera 20% ya mtima wonse ndi:
- 0,5 ml ya mtima;
- 1,0ml wa kuganizira.
Zotsatira zoyipa
Ndi tsankho kwa mankhwalawa, kuphwanya nthawi ya makonzedwe, mlingo, khungu zimachitika mu mawonekedwe a kuyabwa, kuuma, redness zitha kudziwika. Mukamagwiritsa ntchito mano - kudetsa enamel mano, kuphwanya kukoma, mapangidwe a tartar.
Ndi tsankho kwa mankhwalawa, kuphwanya nthawi ya makonzedwe, mlingo, khungu zimachitika mu mawonekedwe a kuyabwa, kuuma, redness zitha kudziwika.
Malangizo apadera
Njira yothetsera Chlorhexidine imagwira ntchito mwachangu ndikamawotha, koma imawola pa + 100 ° C. Pewani chithandizo chowononga msana, chigaza, khutu lamkati. Zilonda pafupi ndi nerve ganglia sizichiritsidwa ndi chlorhexidine.
Kodi ndingasambe kumaso?
Kugwiritsa ntchito mankhwala a chlorhexidine posamba m'maso sikuloledwa, kupatula madontho amaso omwe ali nawo. Mwakuchita izi, yankho la 0,05% limagwiritsidwa ntchito pochotsa mafinya kuchokera pansi pa eyelids ndi conjunctivitis. Komabe, muyenera kuwonetsetsa kuti mankhwalawo samakhala pa nembanemba ya mucous.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa alibe machitidwe, motero palibe choletsa kugwiritsa ntchito kwake panthawi yomwe ali ndi pakati. Iwo ali osavomerezeka kuchiza ming'alu m'matumbo a mawere nthawi yakudya, kuti musayambitse kuwotcha kwa mucous membrane wamkamwa mwa mwana ndi mankhwalawa m'mimba.
Mankhwalawa alibe machitidwe, motero palibe choletsa kugwiritsa ntchito kwake panthawi yomwe ali ndi pakati.
Kodi chlorhexidine angaperekedwe kwa ana?
Mu malangizo, mankhwalawa ali osavomerezeka kwa ana osakwana zaka 12.
Bongo
Pogwiritsa ntchito zakunja, milandu ya bongo sizinadziwike. Ngati kuchuluka kwa mankhwalawa kulowa m'matumbo, kuledzera kwambiri kumachitika, limodzi ndi zizindikiro za kulephera kwa impso ndi chiwindi. Pankhani ya poizoni, ndikofunikira kuti muzitsuka m'mimba ndi mkaka, yankho la wowuma kapena gelatin ndikupereka koyamwa.
Kuchita ndi mankhwala ena
Mankhwalawa sagwiritsidwa ntchito ndi ayodini kupatula zotupa pakhungu. Sopo ndi anionic othandizira amasokoneza zochita za chinthu. Mitundu yamchere yamchere ya inorganic acid imapangika osapindulitsa ndi 0,5% chlorhexidine.
Analogi
Miramistin ndi hydrogen peroxide, zomwe ndi fanizo la chlorhexidine malinga ndi momwe akuchitira, ali m'gulu la antiseptics. Analogue yathunthu ndi Heoticon.
Miramistin ndi wa gulu la antiseptics, womwe ndi mndandanda wa chlorhexidine malinga ndi momwe akuchitira.
Kusungika kwa mankhwala Chlorhexidine
Sungani pamalo owuma, amdima, ozizira.
Alumali moyo wa mankhwala
Kutengera mtundu wa Mlingo, moyo wa alumali ulinso woposa zaka 2-3.
Kupita kwina mankhwala
Mankhwala oti mugule mankhwala safunika.
Kodi chlorhexidine ndi zingati?
Mtengo wa mankhwalawa umatengera mawonekedwe, voliyumu, wopanga, dera. Mtengo wa mayankho umasiyana 10 mpaka 200 ma ruble, ma supplementories - pafupifupi 155 208 ma ruble, kutsitsi - kuchokera ma ruble 19 pa 100 ml, gel - kutengera kapangidwe kake.
Ndemanga ya Chlorhexidine
Maxim, wazaka 25, Kemerovo: "Ndimasungabe yankho la Chlorhexidine nthawi zonse. Ndimangopereka mabala ndi kumeta, ndimagwiritsa ntchito kumeta, komanso ndimagwiritsa ntchito popanga nsapato ndi miyendo."
Ilana, wazaka 18, Kiev: "Ndimapukuta nkhope yanga ndi njira ya Chlorhexidine pomwe ziphuphu ziwoneka. Sindinayambe ndalephera mankhwalawa. Ndimalimbikitsa kwa anzanga, chifukwa imagwira ntchito mwachangu ndi ziphuphu. Ndipo izi ndizofunikira kwa amayi ndi atsikana onse omwe ali ndi zokwanira khungu lamavuto. "
Galina, wazaka 30, ku Moscow: "Ngakhale ndi njira yotsika mtengo, imagwira ntchito bwino. Ndakhala ndikutenga Chlorhexidine kwazaka zambiri ndimavuto pakhosi kwathu komanso kwa mwamuna wanga. kusapeza bwino pakamwa ndi pakhosi. "