Torvacard ndi mankhwala omwe amapezeka m'gulu la statin. Mothandizidwa, mankhwalawa anali othandiza pothandiza odwala omwe ali ndi mtima matenda a mtima, kukhalapo kwa milingo ya lipids m'magazi. Nthawi zambiri zotchulidwa ngati prophylactic, zimachepetsa chiopsezo cha kufa.
ATX
Malinga ndi gulu la mankhwala, mankhwalawo ali ndi code C10AA05. Zomwe zimagwira ndi atorvastatin.
Torvacard ndi mankhwala omwe amapezeka m'gulu la statin.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala amapezeka piritsi. Mu mawonekedwe amatha kukhala owongoka kapena ozungulira biconvex, wokutidwa ndi chipolopolo.
Katemera - zojambulazo ndi zozungulira pulasitiki, chilichonse chili ndi mapiritsi 10. Timatumba tadzaza timatakata takhadi, tokhala mapiritsi osiyanasiyana (30 kapena 90).
Zomwe zimapangidwazo zimaphatikizapo zinthu zomwe zimagwira komanso zina.
Katemera - zojambulazo ndi zozungulira pulasitiki, chilichonse chili ndi mapiritsi 10.
Mndandanda wazinthu zogwira ntchito:
- calcium wa atorvastatin mu 10, 20 mg kapena 40 mg (izi zimawonetsa ma CD).
Monga zowonjezera zomwe zilipo:
- magnesium wakuba;
- ma cellcose a microcrystalline;
- otsika otsika hyprolose;
- colloidal silicon dioxide;
- magnesium oxide;
- lactose monohydrate;
- croscarmellose sodium.
Utoto wa kanema umapangidwa kuchokera ku talc, macrogol 6000, titanium dioxide wambiri ndi hypromellose 2910/5.
Zotsatira za pharmacological
Mankhwalawa ndi woimira gulu la mankhwala a statins, HMG inhibitors. Mankhwalawa angakhudze kuchuluka kwa triglycerides, plasma cholesterol, metabolites yogwira.
Mankhwalawa ndi woimira gulu la mankhwala a statins, HMG inhibitors. Mankhwalawa angakhudze kuchuluka kwa triglycerides, plasma cholesterol, metabolites yogwira.
Katundu wa magazi amagawidwa mthupi lonse ndikufalikira. Imagwira munjira zingapo:
- kuchuluka kwa cholesterol yafupika ndi 30-46%;
- 30-50% amatha kuchepetsa zomwe apolipoprotein;
- amachepetsa zomwe zimapezeka mu LDL receptors ndi 41-61% (index low lowens lipoprotein);
- mpaka 33% imatha kuchepetsa kuchuluka kwa triglycerides;
- kuchuluka kwa apolipoprotein A ndi HDL cholesterol m'magazi kumachuluka.
Kuchita mayeso ambiri kwatsimikizira kugwiritsidwa ntchito kwakukulu kwa mankhwalawa. Zimapatsa chidwi chodabwitsa ngakhale kwa odwala omwe mankhwalawo omwe amapezeka ndi mankhwala a statin sanathe.
Pharmacokinetics
Pharmacokinetics ili ndi zotsatirazi. Nthawi iliyonse akakhazikitsa mankhwalawa, HMG-CoA reductase enzyme imatsekedwa kwa maola 20 mpaka 30.
Kudya chakudya molumikizana ndi kumwa mapiritsi kumachedwetsa ntchito yogwira ntchito, koma izi sizimachepetsa kugwira ntchito.
Excretion imachitika pamlingo waukulu kudzera m'matumbo. Ndi mkodzo, palibe oposa 2% omwe amachotsedwa.
Kudya chakudya molumikizana ndi kumwa mapiritsi kumachedwetsa ntchito yogwira ntchito, koma izi sizimachepetsa kugwira ntchito.
Zizindikiro zogwiritsidwa ntchito
Mu mawonekedwe a achire ndi prophylactic wothandizila mankhwala zotchulidwa zotsatirazi milandu:
- Hypercholesterolemia yoyamba, mtundu wophatikiza wa hyperlipidemia. Pathology imatha kuyimiridwa ndi hypercholesterolemia ya banja la heterozygous komanso osakhala banja. Muzochitika izi, mankhwala amaphatikizidwa ndi zakudya zapadera.
- Dysbetalipoproteinemia (malinga ndi Fredrickson mtundu wa III) ndi mulingo wambiri wa seramu TG (malinga ndi Fredrickson mtundu IV).
- Matenda ena a mtima. Pankhaniyi, mankhwalawa amaperekedwa kwa odwala omwe ali pachiwopsezo cha matenda a mtima. Awa akhoza kukhala anthu opitilira 55 omwe adadwala sitiroko, atakhala ndi mbiri yakale yosuta, komanso akudwala matenda ashuga. Kuphatikiza apo, imatha kukhala ochepa matenda oopsa kapena kumanzere kwamitsempha yamagazi.
Contraindication
Malangizo ogwiritsira ntchito mayina matenda angapo ndi omwe sanalimbikitsidwe kupereka mankhwala:
- matenda a chiwindi (omwe ali amtundu wogwira);
- kulephera kwa chiwindi (makamaka milandu yomwe ili pa sikelo ya Mwana-Pugh yakuuma A ndi B);
- Hypersensitivity wa wodwala kumodzi kapena angapo zigawo zamankhwala;
- mwa akazi, nthawi yoyembekezera komanso yoyamwitsa;
- angapo matenda obadwa nawo amakhudzana ndi tsankho kapena kuchepa kwa lactose;
- ana ndi achinyamata osakwana zaka 18 (zotsatira za mankhwalawa kwa ana sizinaphunzire).
Ndi chisamaliro
Mndandanda wa contraindication sunaphatikizepo zochitika zina zamatenda ndi matenda momwe chinthu chogwira ntchito chimatha kusokoneza kugwira ntchito kwa ziwalo zamkati. Pamaso pa zotsatirazi, dokotala atha kupatsa wodwalayo chithandizo moyang'aniridwa:
- kusokonezeka kwa metabolic kapena endocrine;
- kukhalapo kwa uchidakwa kwa wodwala;
- khunyu yosalamulirika;
- kusokoneza bwino kwamagetsi osankhidwa ndi madzi, amadziwika ndi mawonetsedwe omveka;
- kukhalapo kwa mbiri ya matenda a chiwindi (transaminases);
- ochepa hypotension;
- matenda a shuga;
- matenda pachimake okhudzana ndi kwambiri (imodzi mwa zitsanzo ndi sepsis);
- kukhalapo kwa rhabdomyolysis.
Ngati wodwalayo ali ndi chidakwa, dokotala atha kukulemberani mankhwalawo moyang'aniridwa kwambiri.
Momwe mungatenge Torvacard
Kuchiza ndi kupewa kugwiritsa ntchito mapiritsi kuyenera kuchitika limodzi ndi mankhwala a lipid-kuchepetsa (achire zakudya). Izi zimakhudza kwambiri zotsatira zamankhwala.
Mlingo wa mankhwalawa kwa wodwala aliyense amawerengeredwa payekhapayekha, kutengera matendawa ndi mankhwala ena.
Nthawi zambiri kuchuluka kwa mankhwalawa kumalangizidwa kuti kuchepa pang'ono. Chifukwa chake, kumayambiriro kwa chithandizo, mlingo wa tsiku ndi tsiku umatha kufika 10 mg ndikuwonjezeka mpaka 80 mg.
Mlingo wa tsiku ndi tsiku womwe adalandira dokotala amatengedwa nthawi 1. Palibe zofunika zapadera pakudya. Mapiritsi amatha kumwedwa pamimba yopanda kanthu, musanadye, mukatha kudya kapena. Njira yotsirizirayi ndiyomwe imakonda kwambiri.
Kuti mupeze chithandizo cha panthawi yake pamene mukumwa mankhwala kuchokera pagulu la statins, wodwalayo amayenera kuyesedwa pafupipafupi. Kuchita bwino kumayamba kuwonekera m'masiku 10-14, ndipo kuchuluka kokwanira kumatha masabata 4 kuyambira poyambira kugwiritsidwa ntchito.
Ndi matenda ashuga
Atorvastatin amatha kuwonjezera shuga wamagazi, zomwe zimawonjezera mwayi wokhala ndi matenda ashuga. Mwa odwala omwe apezeka kale, zimawonjezera kuchuluka kwa glucose pang'ono.
Atorvastatin amatha kuwonjezera shuga wamagazi, zomwe zimawonjezera mwayi wokhala ndi matenda ashuga.
Komanso, kupewa matenda a mtima (matenda ochepa), IHD) mwa anthu omwe amakonda kutukuka kwawo ndikofunikira kwambiri kuposa zovuta zina. Lamulo lofunika mankhwalawa a statins ndikutsatira Mlingo komanso kuyeserera pafupipafupi.
Zotsatira zoyipa
Zotsatira zoyipa mukamamwa mankhwalawa ndizosowa. Odwala ambiri amalola kulandira chithandizo bwino.
Komabe, wopangayo akuchenjeza za mawonekedwe omwe angachitike pakuwonekera kwa thupi. Kukhalapo kwa chizindikiro chimodzi kapena china kumafuna kuthetsedwera kwa mankhwalawo komanso kuchezera kwa dokotala.
Matumbo
Njira yogaya chakudya imatha kuyankha ndikusintha kwa chopondapo (kutsegula m'mimba kapena kudzimbidwa), dyspepsia, nseru. Nthawi zina, pamakhala ululu wam'mimba, kusanza komanso mawonekedwe a kapamba.
Nthawi zina, mutamwa mankhwalawa, kupweteka kwam'mimba, kusanza ndi mawonekedwe a kapamba amatha kuyang'aniridwa.
Hematopoietic ziwalo
Mwa odwala ena, kuchuluka kwa plasma ya atorvastatin kungayambitse lymphadenopathy, thrombocytopenia, kapena magazi m'thupi.
Pakati mantha dongosolo
Mndandanda wazotsatira zamtunduwu ukhoza kuphatikizapo:
- mavuto osiyanasiyana ogona - uku ndikusowa tulo, komanso kusowa tulo, komanso mawonekedwe a zoopsa;
- mutu
- Nthawi zina, paresthesia (kumva kugunda kwa mikono, miyendo, kapena ziwalo zina zamthupi);
- kukokana
- kuchuluka kukwiya m'maganizo (kotchedwa hyperesthesia);
- chizungulire pafupipafupi;
- maulendo okhumudwa.
Kuchokera kumbali yamanjenje yapakati, kupweteka kwa mutu, chizungulire kumatha kuchitika.
Kuchokera kwamikodzo
Nthawi zina, maonekedwe a yade, cystitis, kwamikodzo kusagona. Amuna ali ndi chiopsezo chakusabala. Akazi adapezeka kuti akutuluka magazi mu ukazi.
Kuchokera ku kupuma
Madokotala amazindikira kuti zimachitika kupweteka kwambiri mu trachea ndi pharynx, nosebleeds, ndi matenda am'mapapo.
Kuchokera ku chitetezo chamthupi
Kuyankha kofala kwambiri pakumwa mapiritsi ndimomwe thupi limasokoneza, lomwe limafotokozedwa ndi kuyabwa, zotupa, komanso kutupa pang'ono.
Kuyankha kofala kwambiri pakumwa mapiritsi ndimomwe thupi limasokoneza, lomwe limafotokozedwa ndi kuyabwa, zotupa, komanso kutupa pang'ono.
Kuchokera kumbali ya kagayidwe
Zina mwazotsatira izi ndi hypoglycemia kapena hyperglycemia, kuchepa kwambiri kwa thupi (anorexia) kapena, mutero, kuwonda.
Pa mbali ya gawo la masomphenyawo
Pali njira zingapo zoyenera kuchitikira - uku ndi kuchepa kwa kumveka bwino kwa masomphenyawo, kumverera kwa maso owuma, nthawi zina zotupa m'maso ndizotheka.
Pa mbali ya chiwindi ndi biliary thirakiti
Pali chiopsezo chochepa chotengera ma pathologies monga cholestasis, chiwindi, ndi hepatitis.
Malangizo apadera
Perekani yankho kuti mubwezeretse cholesterol yokhazikika pokhapokha ngati mugwiritsa ntchito mankhwala othandizira, kuchuluka kwa thupi, kuchepa thupi (kwa anthu omwe ali onenepa kwambiri).
Ma biochemical magawo a hepatic ntchito amafunika kuwunika pafupipafupi. Mlingo wawo umawunika pa 6 ndi masabata 12 atayamba chithandizo. Malonda owonjezera amafunikira mutachulukitsa kuchuluka kwa mankhwalawa.
Kuyenderana ndi mowa
Mukamamwa statin, ndikofunika kusiya kumwa zakumwa zoledzeretsa. Izi zitha kuyambitsa mavuto.
Mukamamwa statin, ndikofunika kusiya kumwa zakumwa zoledzeretsa. Izi zitha kuyambitsa mavuto.
Zokhudza mphamvu pakuwongolera njira
Malangizowo alibe chilichonse chokhudza kufunika kosiya kuyendetsa magalimoto ndi galimoto.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Amayi onse panthawi yoyembekezera komanso nthawi yoyamwitsa saloledwa kumwa mankhwalawa. Izi zimachitika chifukwa chakuipa kwa zinthu zomwe zikukhudzidwa pa thanzi ndi moyo wa mwana wosabadwa. Sitikulimbikitsidwa kuperekanso mankhwalawa kwa amayi omwe ali ndi zaka zakubala omwe amagwiritsa ntchito njira zolerera za kulera.
Kupangira Torvacard kwa ana
Kwa ana ndi achinyamata osakwana zaka 18, mankhwalawa saikidwa. Zambiri pazokhudzana ndi zinthu zomwe zimagwira thupi la ana sizipezeka.
Gwiritsani ntchito mu ukalamba
Mankhwala omwe mumalandira amachokera pakuzindikira wodwala kapena mbiri yachipatala. Asanayambe maphunziro a mankhwalawa komanso nthawi ya chithandizo, dokotala amayenera kuwunika momwe wodwalayo alili.
Kulembera odwala okalamba kumatengera kuzindikira kapena mbiri yakudwala.
Bongo
Mankhwala osokoneza bongo amawonekera ndi zizindikiro zomwe zimakhalapo ngati mavuto. Palibe mankhwala enieni a chinthu ichi. Kubwezeretsa thanzi labwinobwino, chithandizo chamankhwala chimachitika.
Kuchita ndi mankhwala ena
Atorvastanin wogwiritsidwa ntchito munthawi yomweyo amatha kusintha zomwe zimachitika ndikuwonetsa ntchito za mankhwala ena.
- Ndi othandizira a immunosuppressive ndi antifungal. Zinthu zomwe zimayamba kugwira ntchito zimayamba kugwira ntchito pang'ono (gawo lochepetsedwa lomwe limapezeka m'magazi).
- Ndi aluminium ndi sodium hydroxide. Kuzindikira kumachepetsedwa ndi wachitatu.
- Ndi spironolactone, cimetidine, ndi ketoconazole, mahomoni amkati mwa sodium nthawi zambiri amachepetsedwa.
- Pogwiritsa ntchito Colestipol, gawo lomwe limagwira ntchito limachepetsedwa ndi kotala.
- Ndi njira zakulera za pakamwa. Imagwira nawo okhawo omwe ali ndi norethindrone kapena ethinyl estradiol. Potere, kuchuluka kwa norethindrone ndi ethinyl estradiol m'magazi kumawonjezeka.
Wopanga
Kampani Zentiva ikugwira ntchito yopanga mankhwala ndi ma pulayimale oyamba, ili ku Slovak Republic.
Kampani Zentiva ikugwira ntchito yopanga mankhwala ndi ma pulayimale oyamba, ili ku Slovak Republic.
Kulongedza kwachiwiri kumachitika ndi onse a Zentiva komanso kampani yaku Russia Zio-Zdorovye CJSC (ku Moscow).
Analogi
Atorvastatin imagwira ntchito ngati yomwe imagwiritsidwa ntchito, kotero mankhwalawa omwe gawoli limapangidwanso amakhala ndi vuto lofananalo. Kuphatikiza apo, pali mitundu ingapo ya mankhwala omwe ali ndi mawonekedwe osiyana, koma machitidwe ofanana.
Analogs:
- Lipona
- Vazator;
- Atomax;
- Rosuvastatin;
- Tulip;
- Atoris;
- Liprimar.
Tulip ndi analogue ya Torvacard.
Kupita kwina mankhwala
Kugula mankhwala kumafuna mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Malinga ndi malangizo, mankhwalawa samaperekedwa popanda mankhwala a dokotala.
Mtengo wa Torvacard
Mtengo wa mankhwala umatengera magawo angapo: kuchuluka kwa mapiritsi m'mpaketi imodzi, mfundo yamitengo yamapiritsi.
Zosungidwa zamankhwala
Mankhwalawa safuna malo osungika apadera.
Alumali moyo wa mankhwala Torvakard
Mikhalidwe yosungidwa bwino, mankhwalawa amatha zaka 4.
Ndemanga ya Torvacard
Kwazaka zambiri zomwe zakhala m'msika wa pharmacology, mankhwalawa adadziyambitsa okha othandiza kwambiri. Izi zikuwonetsedwa ndi kuwunika kwa madotolo ndi odwala.
Omvera zamtima
Konstantin, wamtima wazaka, wazambiri zakuchipatala pazaka 14
Kwa odwala omwe ali ndi matenda a mtima (coronary mtima matenda), mankhwalawa amapereka mphamvu zambiri. Komabe, izi zimatheka pokhapokha ngati mukudwala. Mwa zabwino ndichofunika kutchulapo zingapo zoyipa ndi zovuta kugwiritsa ntchito.
Kwa odwala omwe ali ndi matenda a mtima (coronary mtima matenda), mankhwalawa amapereka mphamvu zambiri. Komabe, izi zimatheka pokhapokha ngati mukudwala.
Odwala
Irina, wazaka 45, Ufa
Akapezeka ndi matenda a shuga, mankhwalawa adapangidwa, pakati pa mankhwala ena. Ndakhala ndikutenga kwa miyezi ingapo. Ngakhale kuchuluka kwazotsatira zoyipa izi, kunalibe zosasangalatsa. Chokhacho ndikuti nthawi zambiri muyenera kuyesa kuyesa kuwongolera.