Kulemera kwambiri kwa thupi m'thupi la shuga ndi kuchuluka kwa thupi, zomwe zimathandizira kuti pakhale zovuta zina: vuto la mtima, dyspnea, matenda a maso. Formetin amalimbana ndi izi popanda kuyambitsa zovuta.
Dzinalo Losayenerana
INN - Metformin hydrochloride.
Formine ndi hypoglycemic wothandizira yemwe amagwiritsidwa ntchito mu shuga.
ATX
Khodi ya ATX ndi A10BA02.
Kutulutsa mafomu ndi kapangidwe kake
Pali piritsi lamankhwala. Mu katoni mukhonza kukhala mapiritsi 30, 60 kapena 100. Mwanjira ya kuyimitsidwa ndi mitundu ina ya mankhwala, mankhwalawa samapangidwa.
The yogwira ndi metformin hydrochloride muyeso wa 500, 850 kapena 1000 mg. Zoonjezera zina za mankhwalawa ndi:
- croscarmellose sodium;
- magnesium wakuba;
- polyvinylpyrrolidone.
Pali piritsi lamankhwala. Mu katoni mukhonza kukhala mapiritsi 30, 60 kapena 100. Mwanjira ya kuyimitsidwa ndi mitundu ina ya mankhwala, mankhwalawa samapangidwa.
Zotsatira za pharmacological
Ndiwogwiritsa ntchito hypoglycemic wopangidwira kukwaniritsa zotsatirazi:
- kukulitsa kugwiritsira ntchito shuga;
- Kuchepetsa minyewa yopanga shuga yomwe imachitika m'chiwindi;
- kukulitsa chidwi cha minyewa pazotsatira za insulin (chifukwa chake, kuchuluka kwa shuga kwa magazi kumafika);
- Matenda a kulemera;
- kuchepa kwa milingo ya ma lipoprotein otsika ndi triglycerides;
- chepetsa mayamwidwe a shuga opezeka m'matumbo.
Kuphatikiza apo, mankhwalawa sakukhudzanso kubisika kwa insulini mu kapamba ndipo sikuti kumabweretsa mayendedwe achilendo a hypoglycemic.
Pharmacokinetics
Makhalidwe a Forethine:
- zotupa mu mkodzo;
- amadziunjikira impso, chiwindi, minofu minofu ndi gasi a salivary;
- sizimamangirira kumaproteni amwazi;
- bioavailability pafupifupi 50-60%.
Zomwe zimathandiza
Mankhwalawa amagwiritsidwa ntchito ngati mtundu wachiwiri wa matenda a shuga, kutulutsa komwe kumayendetsedwa ndi kunenepa kwambiri chifukwa cha kusowa kwa mphamvu yochokera pakudya.
Mankhwalawa amagwiritsidwa ntchito ngati matenda a shuga 2, omwe amayambitsidwa ndi kunenepa kwambiri.
Contraindication
Malinga ndi malangizo ogwiritsira ntchito, muyenera kupewa kutenga formin ngati muli ndi zotsatirazi:
- chiwindi ndi impso ntchito;
- nthawi pambuyo povulala kowopsa ndi ntchito zovuta;
- poyizoni woledzera;
- zinthu zomwe zimapangitsa kuwonjezeka kwa lactic acid m'magazi (lactic acidosis): kuchepa madzi m'mimba, kulephera kupuma, mavuto okhala ndi magazi, kugunda kwamtima mu gawo lodana kwambiri, kugunda kwa mtima;
- chikomokere ndi mtundu wa matenda ashuga;
- chidwi chachikulu ndi mankhwalawa;
- nthawi yomwe wodwalayo amadya chakudya chamthupi;
- zovuta zama metabolism a carbohydrate, zomwe zimawonekera kumbuyo kwa matenda ashuga (ketoacidosis).
Ndi zoletsedwa kumwa mankhwalawa kwa anthu azaka zopitilira 60 omwe akuchita ntchito yayikulu.
Ndi chisamaliro
Mankhwala ndi mankhwala osokoneza bongo a zaka zopitilira 65, omwe amalumikizidwa ndi chiwopsezo cha lactic acidosis.
Momwe mungatengere FORMETINE
Mlingo wa mankhwalawa amasankhidwa payekhapayekha, poganizira za kuchuluka kwa shuga m'magazi a wodwala. Yambani ndi kuchuluka kwa 500 mg 1-2 kawiri pa tsiku kapena kamodzi pa 850 mg ya mankhwalawa.
Pang'onopang'ono, mlingo umakulitsidwa kwa 2-3 g patsiku. Kuchuluka kwa mankhwalawa sikuyenera kupitirira 3 g patsiku.
Mlingo wa mankhwalawa amasankhidwa payekhapayekha, poganizira za kuchuluka kwa shuga m'magazi a wodwala.
Musanadye kapena musanadye
Kulandila kwa Formetin kutha kuchitika onse mukatha kudya, komanso mukamadya. Mankhwala amaloledwa kumwa ndi madzi.
M'mawa kapena madzulo
Ndikulimbikitsidwa kugwiritsa ntchito mankhwalawa madzulo, omwe kupewa mavuto oyipa m'mimba. Mukamamwa mankhwalawa 2 pa tsiku, mankhwalawa amatengedwa m'mawa komanso madzulo.
Chithandizo cha matenda ashuga
Kugwiritsidwa ntchito kwa formin mu shuga mellitus kumachitika molingana ndi malingaliro omwe adalandira kuchokera kwa dokotala.
Kuchepetsa thupi
Pali zambiri zokhudzana ndi kugwiritsa ntchito mankhwalawa kuti muchepetse kunenepa, koma malangizo aboma savomereza kugwiritsa ntchito mankhwalawa.
Ndikulimbikitsidwa kugwiritsa ntchito mankhwalawa madzulo, omwe kupewa mavuto oyipa m'mimba.
Zotsatira zoyipa
Matumbo
Ndi kukula kwa zovuta zomwe zimakhudza dongosolo logaya chakudya, wodwalayo amayamba kudandaula za zotsatirazi:
- kutaya mtima;
- kusasangalala m'mimba;
- nseru
- chisangalalo;
- kukoma koyipa mkamwa;
- kutsegula m'mimba
- kusanza.
Kusanza ndi mseru ndi zina mwazotsatira zoyipa zamankhwala kuchokera m'mimba.
Hematopoietic ziwalo
Nthawi zina, anthu omwe amagwiritsa ntchito mankhwalawa amakhala ndi vuto la kuchepa kwa magazi m'thupi. Pankhaniyi, kuphwanya kukuwoneka ndi zizindikiro:
- kumverera kozizira;
- phokoso mokhumudwa;
- kukana nyama;
- kufooka kwathunthu;
- paresthesias;
- dzanzi la miyendo;
- kusakhazikika.
Pakati mantha dongosolo
Zotsatira zoyipa zimatha kubweretsa zotsatirazi:
- kuyerekezera;
- kukokana
- Kuda nkhawa
- kusokonekera;
- kutopa.
Kuchokera kumbali ya kagayidwe
Ndi chithandizo cha nthawi yayitali ndi Formetin, kusowa kwa vitamini B12 kumachitika. Nthawi zina, lactic acidosis imapangidwa.
Dongosolo la Endocrine
Kukhazikitsidwa kwa mankhwala mosayenera kungapangitse kuchepa kwa shuga ndende (hypoglycemia).
Matupi omaliza
Thupi lawo siligwirizana limadziwika ndi mawonekedwe a totupa pakhungu.
Malangizo apadera
Pa mankhwala, ntchito ya impso iyenera kuyang'aniridwa.
Zokhudza mphamvu pakuwongolera njira
Mukamatenga Formetin, palibe zoyipa pakuyendetsa. Komabe, kugwiritsa ntchito mankhwalawa limodzi ndi insulin kapena zinthu zina zochokera mu sulfonylurea kumapangitsa kuti chiwongolero chitha kuyendetsa galimoto chifukwa chophwanya ntchito za psychomotor.
Kupangira Fomu ya Ana
Palibe chidziwitso pakugwiritsa ntchito mankhwalawa pochiza ana osakwana zaka 10, chifukwa chake, palibe mankhwala omwe adalembedwa panthawiyi.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mukamayamwitsa komanso kunyamula mwana, mankhwalawa sagwiritsidwa ntchito.
The ntchito aimpso kuwonongeka
Kupezeka kwa kwambiri aimpso pathologies ndi kutsutsana.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Gwiritsani ntchito mankhwala kuphwanya chiwindi koletsedwa.
Bongo
Kutenga mankhwalawa mu Mlingo waukulu kumabweretsa lactic acidosis. Ngati palibe kulowererapo, vutoli limatha kukhala lakufa.
Kuchita ndi mankhwala ena
Sitikulimbikitsidwa kuphatikiza kugwiritsa ntchito fayilo imodzi ndi mitundu yotsatira.
- anticoagulants okhudzana ndi zotumphukira za coumarin - zovuta zamankhwala zimachepa;
- phenothiazine, mankhwala okodzetsa a mtundu wa thiazide, glucagon, mankhwala opatsirana pakamwa - mphamvu ya gawo lomwe limagwiritsidwa ntchito ndi mankhwala limachepetsedwa;
- cimetidine - chimbudzi cha metformin chochokera m'thupi la wodwalayo chayamba kuchuluka;
- chlorpromazine - chiopsezo cha hyperglycemia chikuwonjezeka;
- danazol - mphamvu ya hyperglycemic imatheka;
- Ma inhibitors a ACE ndi ma MAO otumphuka kwa clofibrate ndi NSAIDs - zofunikira za formin zikuwonjezeka.
Kuyenderana ndi mowa
Kugwiritsa ntchito zakumwa zokhala ndi zakumwa zoledzeretsa kumawonjezera chiopsezo cha lactic acidosis.
Muyenera kupewa kumwa mowa kuti muchepetse kukula kwa lactic acidosis.
Analogi
Mankhwala akhoza m'malo ndi analogues.
Zida izi ndi:
- Glucophage - mankhwala ochepetsa hyperglycemia.
- Siofor - mankhwala omwe ali m'gulu la Biguanides. Imakhala ndi phindu pa metabolidi ya lipid ndikuchepetsa gluconeogeneis.
- Forin Long ndi mtundu wa mankhwala womwe amakhala ndi 500, 750, 850 kapena 1000 mg.
- Gliformin ndi mankhwala omwe cholinga chake ndi kuchepetsa kuchuluka kwa triglycerides ndi LDL. Mankhwala amatha kuchedwetsa gluconeogeneis.
- Metformin - mankhwala omwe ali ndi chiwalo chimodzi, omwe amapezeka mu 0,5 kapena 0,85 g.
- Bagomet ndi mankhwala a hypoglycemic omwe cholinga chake ndi pakamwa.
Kupita kwina mankhwala
Kuti mugule Formetin, muyenera kulandira mankhwala kuchokera kwa dokotala.
Kodi ndingagule popanda kulandira mankhwala?
Amamasulidwa pa chiwonetsero cha Chinsinsi.
Mtengo wa formin
Mankhwalawa atha kugulidwa kwa ma ruble 50-240.
Zosungidwa zamankhwala
Mankhwalawa ayenera kutetezedwa ku kutentha ndi chiwonetsero cha ultraviolet.
Tsiku lotha ntchito
Chochita chimaloledwa kusungidwa kwa zaka ziwiri.
Wopanga
Kampani ya Pharmstandard-Leksredstva ikugwira nawo ntchito yotulutsidwa kwa Formetin.
Njira yothetsera vutoli imatulutsidwa.
Umboni wa madotolo ndi odwala za Formetin
Arseny Vladimirov, endocrinologist wazaka 54, Moscow
Kugwiritsa ntchito formin ndi chipulumutso kwa odwala omwe ali ndi kunenepa kwambiri chifukwa cha matenda ashuga. Chipangizocho chimasintha matenthedwe amasinidwe a insulin, osapereka mphamvu pakadwala. Ubwino wina ndi mtengo wotsika mtengo.
Valentina Korneva, endocrinologist, wazaka 55, Novosibirsk
Mankhwalawa ndi othandiza. Ndimapereka mankhwala kwa odwala anga nthawi zambiri. Palibe amene adadandaula za zotsatira zoyipa. Ndipo mkhalidwewo ukukonzanso.
Victoria, wazaka 45, Volgograd
Mothandizidwa ndi Forthin, ndimasunga kulemera, monga chifukwa cha matenda ashuga, adayamba kuchuluka. Mankhwalawa ndiokwera mtengo, akupezeka ku Russia. Ndimamwa mankhwalawa madzulo. Komabe, muyenera kutsatira zakudya, kupatula mbale ndi zinthu zomwe zili ndi zopatsa mphamvu.
Dmitry, wazaka 41, Yekaterinburg
Ndakhala ndikuwathandizira kwa nthawi yayitali, Ndili ndi matenda ashuga kwa zaka zoposa 15. Mankhwala amathandiza, osakhala ndi mavuto. Mankhwala amatengedwa 2 pa tsiku piritsi.
Maria, wazaka 56, Saratov
Ndakhala ndikuvutika ndi matenda ashuga pafupifupi zaka 5. Nthawi yonseyi, Gliformin adagwiritsa ntchito, zomwe adokotala adamuuza. Mankhwalawa adathandizira, chifukwa chake ndimatha kuwagwiritsa ntchito mopitilira, koma ndikamapita kuchipatala adati palibe mankhwalawa. Forethine adasankhidwa kuti alowe m'malo. Ndinkawopa kuti kusintha mankhwala kungandibweretsere mavuto ena, koma zidatha. Thupi linalekerera mankhwalawa bwino, motero ndikupitiliza kuigwiritsa ntchito.
