Diameride ndi othandizira a hypoglycemic omwe odwala 2 a shuga amatenga kuti achepetse magazi. Kuchiza ndi mankhwalawa kumachitika moyang'aniridwa ndi achipatala.
Dzinalo Losayenerana
Dzinalo losavomerezeka la mankhwalawa ndi glimepiride. Zikutanthauza chida chogwira ntchito ngati mankhwala. Katunduyu ndi m'badwo wachitatu wa sulfonylurea.
Diamerid ndi mankhwala omwe amagwiritsidwa ntchito kutsitsa glucose wamagazi.
ATX
Mndandanda wa mankhwalawa malinga ndi ATX (anatomical, achire komanso mankhwala gulu) ndi A10BB12. Ndiye kuti, mankhwalawa ndi chida chomwe chimakhudza gawo logaya chakudya komanso kagayidwe, kamapangidwa kuti athetse matenda a shuga, amadziwika kuti ndi chinthu cha hypoglycemic, chotengera cha sulfonylurea (glimepiride).
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka pamapiritsi. Mawonekedwe a mapiritsiwo ndi linda lathyathyathya wokhala ndi bevel. Utoto umatengera kuchuluka kwa zosakaniza piritsi; zitha kukhala zachikaso kapena zapinki.
Mapiritsi amatha kukhala ndi 1, 2, 3 mg kapena 4 mg ya mankhwala othandizira.
Omwe amathandizira ndi: lactose monohydrate, magnesium stearate, povidone, microcrystalline cellulose, poloxamer, croscarmellose sodium, utoto.
Phukusi limodzi lili ndi matuza atatu, iliyonse ya 10 ma PC.
Zotsatira za pharmacological
Mankhwalawa ali ndi vuto la hypoglycemic. Kuchita kwa mankhwalawa kumakhazikika pakulimbikitsa kupanga kwa insulin ndi maselo a beta a pancreatic a Langerhans, komanso kukulitsa chidwi cha zolandilira minofu ku mahomoni ndikuwonjezera kuchuluka kwa mapuloteni a glucose transporter m'magazi. Kuchita pancreatic minofu, mankhwalawa amachititsa kukokoloka kwake ndikutsegulidwa kwa njira zama calcium zomwe zimadalira magetsi, chifukwa cha momwe ma cell amayambitsa.
Amachepetsa kuchuluka kwa gluconeogenesis m'chiwindi chifukwa chotchinga ma enzymes ofunikira, motero kukhala ndi zotsatira za hypoglycemic.
Mankhwala amakhudzanso kuphatikiza kwa maselo ambiri, kumachepetsa. Imalepheretsa cycloo oxygenase, kutsekereza kukhathamiritsa kwa arachidonic acid, kumakhala ndi antioxidant, kumachepetsa kuchuluka kwa lipid peroxidation.
Pharmacokinetics
Ndi kugwiritsa ntchito pafupipafupi, 4 mg tsiku lililonse, mlingo waukulu wa mankhwala m'magazi umawonedwa pakatha maola awiri ndi atatu. Mpaka 99% ya zinthu zomwe zimamangiriza mapuloteni a seramu.
Hafu ya moyo ndi maola 5-8, chinthucho chimapukusidwa mu mawonekedwe a metabolised, sichidziunjikira m'thupi. Amadutsa placenta ndikudutsa mkaka wa m'mawere.
Zizindikiro zogwiritsidwa ntchito
Type 2 shuga mellitus, ngati mankhwalawa akudya ochepa-carb komanso kuchita masewera olimbitsa thupi nthawi zonse samapereka zotsatira zofunika.
Contraindication
Kulandila sikulimbikitsidwa mu milandu yotsatirayi:
- mtundu 1 matenda a shuga;
- matenda a shuga komanso chiwopsezo cha chitukuko;
- zinthu za hypoglycemic zomwe zimachitika pazifukwa zosiyanasiyana;
- kuchuluka kwa maselo oyera;
- kukanika kwambiri kwa chiwindi;
- kukanika kwa aimpso, kugwiritsa ntchito zida zochitira impso;
- mimba
- kuyamwitsa;
- ana ochepera zaka 18;
- malabsorption syndrome ndi kuphwanya kwa chimbudzi cha lactose.
Kodi kumwa diamerid?
Mukamamwa mankhwalawa, dokotala amayenera kuwunika kuchuluka kwa shuga m'magazi. Katswiriyu amawona kuchuluka kwa shuga m'magazi, omwe ayenera kumwa mankhwalawo. Mlingo wochepetsetsa womwe umagwiritsidwa ntchito, womwe ungagwire bwino ntchito.
Mankhwalawa amapezeka pamapiritsi. Mawonekedwe a mapiritsiwo ndi linda lathyathyathya wokhala ndi bevel.
Ndi matenda ashuga
Mlingo woyambirira ndi 1 mg patsiku. Ndi nthawi ya masabata 1-2, adokotala amawonjezera mlingo, ndikusankha zofunikira. Inunso simungathe, popanda kufunsa dokotala, kuyamba kumwa mankhwalawo kapena kusintha mankhwalawo, chifukwa ndi othandizira amphamvu, osagwiritsa ntchito molakwika zotsatira zake.
Ndi shuga wolamulidwa bwino, mlingo wa mankhwalawa patsiku ndi 1-4 mg, kutsika kwakukulu sikumagwiritsidwa ntchito kwenikweni chifukwa chakuti amagwira ntchito kwa anthu ochepa okha.
Mukatha kumwa mankhwalawa, simuyenera kulumpha chakudya, chomwe chimayenera kukhala chofinya. Mankhwalawa ndiwotalikirapo.
Diameride tikulimbikitsidwa mtundu 2 shuga mellitus, ngati chithandizo chokhala ndi carb ochepa komanso kuchita masewera olimbitsa thupi pafupipafupi sikuthandiza.
Zotsatira zoyipa za diamerid
Mankhwalawa ali ndi ntchito zambiri, motero ali ndi zotsutsana zambiri.
Pa mbali ya ziwalo zamasomphenya
Pakhoza kukhala vuto la diso: kusawona kwakanthawi kapena kuwona kwa chiwalo chimodzi kapena ziwalo zonse. Zizindikiro zotere zimatha kuchitika kumayambiriro kwa chithandizo chifukwa cha kusintha kwa kuchuluka kwa shuga.
Matumbo
Kusanza, kusanza, kutsekula m'mimba, kupweteka kwam'mimba. Zoyipa zomwe zingachitike mu chiwindi: hepatitis, jaundice, cholestasis.
Hematopoietic ziwalo
Kuchepetsa kwa maselo othandiza magazi, maselo oyera ndi magazi ofiira, magazi m'thupi.
Zotsatira zoyipa za diamerid: kuchepa kwa maselo ambiri, maselo oyera am'magazi ndi maselo ofiira amwazi, kuchepa magazi.
Kuchokera kumbali ya kagayidwe
Yaitali hypoglycemia, yomwe imayendetsedwa ndi mseru, mutu, kusokonezeka ndende. kulakalaka kudya, njala yosalekeza, mphwayi.
Matupi omaliza
Thupi lawo siligwirizana: kuyabwa, redness, zidzolo. Nthawi zina, manenedwe a anaphylactic angayambe.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa amakhudza kuthekera kwa kayendetsedwe ka kayendedwe chifukwa cha kupukusa kwa hypoglycemia, komwe kumayendetsedwa ndi kuchepa kwa ndende, kutopa kosalekeza komanso kugona. Kuthekera kochita ntchito yomwe imafuna kuti anthu azikhala ndi chidwi, kuphatikizapo kuyendetsa magalimoto, imachepetsedwa.
Malangizo apadera
Mukamamwa, ndikofunikira kuganizira za mankhwalawa.
Simungayambe kumwa mankhwalawo kapena kusinthitsa mlingo womwe mwapatsidwa nokha, osakakumana ndi dokotala.
Gwiritsani ntchito mu ukalamba
Pakukalamba, munthu samatha kulankhulana momasuka ndi dokotala, chifukwa chomwe adokotala sangadziwe momwe wodwalayo atamwa ndikusintha dokotalayo, zomwe zimakhudza kuyipa kwa chithandiziro komanso mkhalidwe wa wodwalayo. Chifukwa chake, wodwalayo ayenera kumuuza dotolo zonse zakusintha kwa boma, pozindikira kuti izi ndizofunikira choyamba kwa iye.
Kupatsa ana
Kwa ana ochepera zaka 18, mankhwalawa amatsutsana.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yoyembekezera komanso poyamwitsa, mankhwalawa amakwiririka chifukwa amatha kulowa mkati mwa chotchinga ndikuthira mkaka wa m'mawere, womwe umatha kuvulaza thupi la mwana wosalimba. Chifukwa chake, mayi yemwe adamwa mankhwalawa isanachitike, amapatsirana mankhwala a insulin.
Pa nthawi yoyembekezera komanso poyamwitsa, mankhwalawa amatsutsana
Mankhwala ochulukirapo a diamerid
Pankhani ya bongo, hypoglycemia imawonedwa, yomwe imayendetsedwa ndi mutu, kumva kufooka, kutuluka thukuta kwambiri, tachycardia, mantha ndi nkhawa. Ngati zizindikirozi zikuchitika, muyenera kudya zakudya zopatsa mphamvu mwachangu, mwachitsanzo, idyani shuga. Ngati mankhwala osokoneza bongo ali pachimake, ndikofunikira kutsuka m'mimba kapena kusanza. Mpaka boma lokhazikika lithe, wodwalayo amayenera kuyang'aniridwa ndi achipatala, kuti ngati shuga atachepa kawirikawiri, adokotala amatha kuthandizira.
Kuchita ndi mankhwala ena
Mukamagwiritsa ntchito mankhwalawa ndi mankhwala ena, ndizotheka kufooketsa kapena kulimbitsa machitidwe ake, komanso kusintha kwa ntchito ya chinthu china, chifukwa chake ndikofunikira kudziwitsa adokotala za mankhwala omwe amagwiritsidwa ntchito. Mwachitsanzo:
- Ndi munthawi yomweyo makonzedwe a glimepiride ndi insulin, othandizira ena a hypoglycemic, zotumphukira za coumarin, glucocorticoids, metformin, mahomoni ogonana, angiotensin-akatembenuza enzyme zoletsa, fluoxetine, etc., hypoglycemia yayikulu imatha.
- Glimepiride ikhoza kuletsa kapena kuwonjezera zotsatira za zotumphukira za coumarin - anticoagulant.
- Mafuta, ma laxatives, T3, T4, glucagon amatha kuchepetsa mphamvu ya mankhwalawa, kuchepetsa mphamvu ya mankhwalawa.
- Ma H2 histamine receptor blockers amatha kusintha zotsatira za glimepiride.
Ndi munthawi yomweyo makonzedwe a glimepiride ndi insulin, ena othandizira a hypoglycemic, kukula kwa hypoglycemia ndikotheka.
Kuyenderana ndi mowa
Mlingo umodzi wa mowa kapena kugwiritsa ntchito nthawi zonse kumatha kusintha ntchito za mankhwalawo, kuonjezera kapena kuchepetsa.
Analogi
Ma analogues ndi othandizira omwe amakhala ndi glimepiride ngati chinthu chogwira ntchito. Izi ndi mankhwala monga:
- Amaril. Awa ndi mankhwala aku Germany, piritsi lililonse lomwe mumakhala mulingo wa 1, 2, 3 kapena 4 mg. Kupanga: Germany.
- Glimepiride Canon, Yopezeka mu Mlingo wa 2 kapena 4 mg. Kupanga: Russia.
- Glimepiride Teva. Amapezeka mu Mlingo wa 1, 2 kapena 3 mg. Kupanga: Croatia.
Diabetes ndi mankhwala a hypoglycemic, ali ndi vuto lofanana la hypoglycemic, koma mphamvu yake yogwira ntchito imachokera ku sulfonylurea ya m'badwo wachiwiri.
Amaryl ndi analogue ya Diamerid. Awa ndi mankhwala aku Germany, piritsi lililonse lomwe mumakhala mulingo wa 1, 2, 3 kapena 4 mg.
Kupita kwina mankhwala
Mankhwalawa atha kugulidwa ku pharmacy iliyonse ku Russian Federation.
Kodi ndingagule popanda kulandira mankhwala?
Mankhwala amaperekedwa pokhapokha ngati amupatsa mankhwala.
Mtengo wa diamerid
Mtengo wapakati wa mankhwalawo umachokera ku ruble 202 mpaka 347. Mtengo wake umatengera pharmacy ndi mzinda. Mtengo wa analogues umatengera dziko lakapangidwe.
Zosungidwa zamankhwala
Mankhwalawa amayenera kusungidwa m'malo amdima, kutentha komwe sikupita 25 ° C, osagwirizana ndi ana.
Tsiku lotha ntchito
Zaka 2
Wopanga
Amapangidwa ndi Chemical and Pharmaceutical Plant AKRIKHIN AO, yomwe ili ku Russia.
Chomera ndi mankhwala a AKRIKHIN AO.
Ndemanga za Diamerida
Musanagwiritse ntchito mankhwalawa, muyenera kudziwa za ndemanga zake.
Madokotala
Starichenko V. K. "Mankhwalawa ndi chida chothandiza kuti muchepetse matenda ashuga amtundu wa 2. Chiri chololeka kugwiritsa ntchito mankhwala a insulin kapena monotherapy. Dokotala yekha ndi omwe angatchule ndikuwongolera mlingo."
Vasilieva O. S. "Mankhwalawa amachepetsa kuchuluka kwa shuga m'magazi, kuthana ndi zovuta zomwe zimabweretsa chifukwa cha matenda ashuga. Katswiri wokhayo ndi amene ayenera kulemba mankhwalawo ndikuzindikira mtundu wa mankhwalawo."
Odwala
Galina: "Mwazi wa shuga wamagazi unakwera kwambiri, mankhwala adapangidwa ndi glimepiride yogwira. Mapiritsi ndi omasuka, kumeza bwino, tsiku lililonse musanadye chakudya cham'mawa. Shuga wa m'magazi ndimakhazikika, zizindikiro zosasangalatsa za matenda ashuga zatha."
Natasha: "Mayi anga ali ndi matenda ashuga, mankhwala ena sanathandizire, dokotala adamuwuza mankhwalawo, nati, amathandizira kupanga insulin komanso imapangitsa kumva kwa maselo kwa izo. Shuga ndiyabwinobwino, zimatenga pafupifupi chaka."
