Pali mankhwala ambiri ochepetsa kuthamanga kwa magazi ndikubwezeretsa CVS. Chimodzi mwa izi ndi Lozap AM.
Dzinalo Losayenerana
Losartan ndi dzina lapadziko lonse la mankhwalawa.
Ath
C09DB Angiotensin II okonda kuphatikiza ndi BKK.
Lozap AM ndi mankhwala ochepetsa magazi komanso kubwezeretsa CCC.
Kutulutsa mafomu ndi kapangidwe kake
Lozap ndi piritsi lomwe limakhala ngati chipolopolo. Pali mitundu ingapo yamasulidwe, kutengera ndende ya chinthu chachikulu - 12.5, 50, 100 mg.
Zopangidwa:
- zosakaniza zazikulu ndi losartan potaziyamu;
- microcrystalline cellulose, wowuma, sodium stearate, madzi, crospovidone, silicon dioxide.
Mankhwalawa amagulitsidwa makatoni ama 3, 6 kapena 9 matuza.
Zotsatira za pharmacological
Mankhwalawa ndi a gulu la antihypertensive mankhwala ndipo ali ndi zochitika zingapo:
- amachepetsa kukana konse kwa mitsempha ndi ma capillaries;
- amachepetsa ndende ya adrenaline ya mahomoni, chifukwa imapangitsa ntchito ya minofu yamtima;
- kutsitsa magazi;
- amapanga okodzetsa.
Mankhwala amachepetsa kukana konse kwa mitsempha ndi capillaries.
Hormone anginotensin, motsogozedwa ndi mankhwalawa, imasinthidwa kukhala mahomoni angiotensin ii (ndi AT1 ndi AT2 receptors), yomwe imakhudza vasoconstriction.
Pharmacokinetics
Mankhwalawa amatengeka mwachangu mokwanira kudzera m'mimba ndipo mumayamwa kudzera mu kagayidwe kake ka chiwindi ndi inhibitor ya isoenzyme.
Chilolezo cha plasma cha losartan ndi 600 ml / min, ndipo metabolite yogwira mu plasma ndi 50 ml / min.
Chilolezo cha Lozap - 74 ml / min. Ma metabolabol amamuchotsa m'matumbo ndi impso.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amalembera achikulire ndi ana a zaka 6 zakubadwa:
- matenda oopsa (kuthamanga kwa magazi);
- kupewa myocardial infarction;
- arrhythmia, ischemia ndi matenda ena osachiritsika a CVS;
- matenda oopsa odwala odwala matenda ashuga mellitus.
Contraindication
Mankhwala okhazikika:
- zatsopano;
- azimayi pa nthawi yobereka ndi pakubala;
- ndi hypotension;
- ndi chifuwa ndi tsankho kwa zigawo zikuluzikulu.
Ndi chisamaliro
Mutha kumwa mankhwala ochepa Mlingo wokhala ndi izi:
- kulephera kwa mtima;
- Hyperkalemia
- kusowa kwa madzi m'magetsi;
- ochepa hypotension ana osakwana zaka 6.
Momwe mungatenge Lozap AM
Mapiritsi amatengedwa pakamwa, ngakhale zakudya. Mlingo wokhazikika ndi 50 mg patsiku. Amasinthidwa kutengera umunthu wa wodwalayo. M'matenda a mtima omwe amapezeka kale, mlingo woyamba ndi 12,5 mg. Popanda zovuta, zimawonjezeka mpaka 50 mg kuti zitheke kwambiri.
Popewa matenda amtima wachiwiri, 50 mg amatengedwa 1 nthawi patsiku. Chithandizo cha mankhwalawa chimatha monga momwe wodwala matenda a mtima adanenera.
Kumwa mankhwala a shuga
Simungatenge kumwa kokwanira nthawi yoyamba. Ndikofunikira kuyang'ana momwe thupi limachitikira, motero tikulimbikitsidwa kuti muyambe ndi 50 mg patsiku. Ndi mankhwala ena, mlingo umakulitsa mpaka 100 mg patsiku. Mutha kugwiritsa ntchito nthawi yomweyo 100 mg kapena 50 mg mu 2 seti.
Mu shuga mellitus, kumwa mankhwala okwanira sayenera kumwa nthawi yoyamba.
Zotsatira zoyipa
Ngati mankhwalawo siabwino kwa wodwala kapena akumwa molakwika, mavuto angachitike. Mapiritsi nthawi zambiri amaloledwa, koma zotheka ziyenera kudziwa.
Matumbo
Kuchepa kwa chiwindi, kuperewera kwam'mimba thirakiti, kusokonekera kapena kutsekula m'mimba, kusamva bwino ndi kupweteka pamimba.
Hematopoietic ziwalo
Chifukwa chakuwongolera kosayenera, kuchulukitsa kapena kusowa kwazitsulo, lifiyamu, ndi mavitamini kumatha kuchitika. Chifukwa cha izi, matenda angapo amatuluka - kuchepa kwa magazi, leukocytosis, etc.
Chifukwa chakuwongolera kosayenera, kuchulukitsa kapena kusowa kwazitsulo, lifiyamu, ndi mavitamini kumatha kuchitika.
Pakati mantha dongosolo
Kugona, kusasamala, chizungulire, kusokoneza tulo, kukwiya kwambiri.
Kuchokera kwamikodzo
Kuwonongeka kwa impso, komwe kumayambitsa amyloidosis (sedimentation ya mapuloteni mu chiwalo) kapena acidosis (aimpso katundu chifukwa cha kuchuluka kwa zamchere m'magazi). Urea m'magazi imakwera ndipo kukodza kumalephera.
Kuchokera ku kupuma
Dyspnea ndi infrequent, ochepera 1% ya odwala.
Urticaria ndi kuyabwa kumachitika chifukwa cha matupi awo sagwirizana ndi magawo a mankhwala.
Pa khungu
Urticaria ndi kuyabwa kumachitika chifukwa cha matupi awo sagwirizana ndi magawo a mankhwala.
Kuchokera ku genitourinary system
Pollakiuria ndimayendedwe a pathological omwe amapezeka chifukwa cha kuwonongeka kwa impso. Imadziwulula yokha ndi kukodza pafupipafupi. Chifukwa cha matendawa, kutupa ndi ma pathologies ena amatha kuchitika.
Kuchokera pamtima
Arrhythmia kapena angina pectoris angachitike. Chifukwa cha tsankho, mankhwalawa amakhumudwitsa tricyularia yamitsempha yamagazi.
Kuchokera ku minculoskeletal system
Ululu kumbuyo, mawondo, mikono, matumbo, kufooka miyendo, kupweteka pachifuwa (kuti tisasokonezedwe ndi mtima).
Pollakiuria ndimayendedwe a pathological omwe amapezeka chifukwa cha kuwonongeka kwa impso.
Kuchokera kumbali ya kagayidwe
Kusowa kwa kagayidwe ka mankhwala nthawi zambiri kumachitika pamene mukumwa Lozap ndi mankhwala ena omwe sagwirizana ndi losartan.
Matupi omaliza
Thupi lawo siligwirizana limatheka ndi mankhwala osokoneza bongo kapena kusalolera kwa ena pazomwe zimapangidwa. Kuwonetsedwa ndi zotupa, kuyabwa, khungu rede. Nthawi zina, kutsetsereka kapena kutsokomola kumachitika.
Malangizo apadera
Kuti musavulaze thanzi, musanalandire mankhwala omwe ali ndi antihypertensive mapiritsi, muyenera kuzolowera malangizo enieni ovomerezeka.
Kuyenderana ndi mowa
Mukamagwiritsa ntchito mankhwalawa, ndizoletsedwa kumwa mowa, chifukwa losartan imagwirizana kwathunthu ndi mowa wa ethyl.
Mukamagwiritsa ntchito mankhwalawa, ndizoletsedwa kumwa mowa.
Zokhudza mphamvu pakuwongolera njira
Mutatha kumwa mankhwalawo, palibe kafukufuku yemwe adachitika pazomwe zimachitika komanso kuyendetsa magalimoto. Ndikulimbikitsidwa kupewa kuyendetsa, chifukwa zoyipa zimatha kukhala ndi zotsatira zoyipa - kuzengereza, chizungulire.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa mu oyambilira komanso achitatu, chifukwa pamakhala chiopsezo cha kukula kwamthupi. Pa HBV, sikulimbikitsanso kugwiritsa ntchito mankhwala a antihypertensive kuti musavulaze mwana. Kafukufukuyu adawonetsa kuti losartan ikhoza kuyambitsa kuzizira kwa fetal.
Kulembera Lozap AM kwa ana
Kafukufuku wasayansi pa zatsopano sanachitepo, motero mapiritsi sagwiritsidwa ntchito ngati ana. Ndikulimbikitsidwa kupewa kumwa mankhwalawa kwa odwala ochepera zaka 18. Nthawi zina amalembera ana azaka 6, ngati zotsatira zomwe zikuyembekezeredwa zimaposa zoopsa zomwe zingachitike.
Gwiritsani ntchito mu ukalamba
Pambuyo pa zaka 60, mankhwalawa amathandizidwa kuti mtima usalephereke komanso kuti mupewe kubwereza kwakenso kwa myocardial. Muyenera kumwa 50 mg patsiku.
Pambuyo pa zaka 60, mankhwalawa amathandizidwa kuti mtima usalephereke komanso kuti mupewe kubwerezanso kwa myocardial infarction.
The ntchito aimpso kuwonongeka
Zotsatira zamaphunziro a pharmacokinetic, zidapezeka kuti chifukwa chotenga Lozap, kulephera kwa impso kumatha kupanga, chifukwa chake, anthu omwe ali ndi vuto laimpso amayenera kugwiritsa ntchito mlingo wochepa kamodzi patsiku. Ngati sichinaoneke, ndizotheka kusokoneza machitidwe a thupi, zomwe zingayambitse kupatsirana kwa impso.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Odwala omwe ali ndi mbiri ya kukanika kwa chiwindi, mlingo wocheperako umayikidwa. Ndikulimbikitsidwa kugwiritsa ntchito mankhwalawa moyang'aniridwa ndi dokotala kuti muwone momwe akusunthira ndipo ngati kuli koyenera, musinthe.
Gwiritsani ntchito kulephera kwa mtima
Gawo logwira lingayambitse kusokonezeka kwa mtima, chifukwa chake, ngati vuto lakakomoka lakomoka, ndikofunikira kuyamwa komanso kumwa mankhwalawo pokhapokha ngati dokotala wanena, kuti muchepetse vutolo.
Bongo
Ndi kumwa kolakwika, zotsatira zoyipa zitha kuonekera:
- kuchuluka kwa magazi alanine aminotransferase;
- kuchepa kwambiri kwa magazi;
- vertigo - kusamva kwa makutu, kuchepa kwa chidwi, chizungulire, tinnitus;
- mawonetseredwe a arrhythmia ndikuphwanya mzere wamtima (tachycardia ndi bradycardia).
Ndi mlingo wolakwika, kuwonjezeka kwa magazi alanine aminotransferase tingaoneke.
Ngati bongo, okakamiza diuresis amachitika kuchepetsa ndende ya losartan.
Kuchita ndi mankhwala ena
Mapale angagwiritsidwe ntchito:
- ndi othandizira antihypertensive;
- ndi hydrochlorothiazitis;
- ndi mankhwala okodzetsa ena.
Kuphatikiza kophatikizidwa
Sizoletsedwa kugwiritsa ntchito Lozap kuphatikiza ndi diuretics, zomwe zimapangitsa kuti pakhale potaziyamu, mwachitsanzo ndi Amiloride, Spironolactone, chifukwa hyperkalemia imatha kuyambitsidwa.
Sizoletsedwa kugwiritsa ntchito Lozap kuphatikiza ndi diuretics, zomwe zimapangitsa kuti pakhale potaziyamu.
Osavomerezeka kuphatikiza
Ndikofunika kusiya makonzedwe amodzi a Lozap omwe ali ndi mankhwala okhala ndi lithiamu. Ndi kuwonjezeka kwa lithiamu m'magazi, zovuta zamkati zamanjenje ndi m'mimba zimatha.
Kuphatikiza komwe kumafunikira kusamala
Ndi munthawi yomweyo kugwiritsa ntchito mankhwala omwe si a antiidal a antiidal
Analogi
Ngati pazifukwa zina lozap sichingatengedwe, itha kuthandizidwa ndi mankhwala omwewa:
- pamaziko a hydrochlorothiazitis - Angizar, Amlodipin, Amzaar, Gizaar, Lorista, Lozap kuphatikiza (mankhwala aku Russia);
- pamaziko a candersartan - Kandekor, Kasark, Hizart-N;
- Gawo lalikulu la telmisartan ndi Mikardisplyus, Telpres, Talmista.
Musanagwiritse ntchito analog, muyenera kufunsa katswiri. Kwa odwala okalamba omwe ali ndi tsankho, Lozap m'malo mwake ndi Amlodipine.
Kupita kwina mankhwala
Mankhwalawa amaperekedwa pokhapokha ngati mwalandira mankhwala.
Kodi ndingagule popanda kulandira mankhwala?
Popanda mankhwala, mankhwalawa amatha kuyitanidwa pa famu ya pa intaneti, koma palibe chitsimikizo kuti wogula sangagwere chifukwa cha zinyengo za osakhulupirika ndipo sangapeze zabodza. Ndikwabwino kupita kwa adotolo ndikugula mapiritsi okhazikika kuti musawononge thanzi lanu.
Mtengo wa Lozap AM
Mtengo wa mankhwalawa umatengera mtengo wake. M'madera a Russian Federation, mtengo wamba wa Lozap 5 mg + 50 mg ndi 500 rubles.
Zosungidwa zamankhwala
Sungani ku kutentha kosaposa + 25 ° C kutali ndi dzuwa. Pazifukwa zotetezeka, zibiseni kwa ana.
Popanda mankhwala, mankhwalawa amatha kuyitanidwa ku pharmacy yapaintaneti.
Tsiku lotha ntchito
Moyo wa alumali - osapitilira miyezi 24 kuchokera tsiku lomwe watulutsa. Itha kuwonedwa pamapaketi.
Wopanga
Amapanga mankhwalawa ku Korea, wopanga ndi Hanmi Famu. Co, Ltd.
Ndemanga pa Lozap AM
Ndemanga za chida ichi ndichabwino kuchokera kwa odwala komanso akatswiri.
Omvera zamtima
Svetlana Aleksandrovna, Phlebologist, Rostov-on-Don
Ndikupangira odwala ambiri kuti atenge Lozap, chifukwa imagwira bwino CVS ndikuchepetsa kuthamanga kwa magazi, kupewa matenda ambiri. Kutengera ndi manambala azachipatala, iyi ndi imodzi mwamankhwala abwino kwambiri polimbana ndi matenda oopsa.
Sergey Dmitrievich, katswiri wa zamtima, Irkutsk
Ndikulembera odwala ambiri atachitidwa opaleshoni kuti azikhala ndi zovuta, kuti athane ndi matenda oopsa.
Odwala
Olga Vasilievna, wa zaka 56, Kurganinsk
Ndakhala ndikutenga Lozap kwazaka zoposa 5. Ndili ndi matenda ashuga 2. Mankhwala amakhutira kwathunthu, kupanikizika kumakhala kwacibadwa, palibe mavuto.
Ivan, wazaka 72, Moscow
Dokotala wamtima woletsa matenda a mtima, chifukwa ndili ndi matenda amitsempha yamagazi. Ngakhale zimathandiza, ndimadziona kuti ndine wazaka 30.
