Wessel Douai F 600 ndi gulu la mankhwala omwe ali ndi gawo limodzi. Mankhwala ndi anticoagulant. Izi zikutanthauza kuti ntchito yake yayikulu ndikusintha mamasukidwe akayendedwe amwazi kuti muchepetse chiopsezo chopanga kuchuluka kwa magazi. Mankhwalawa ndi mankhwala, chifukwa amathandizira thupi kupweteka ndipo sangathe kugwiritsidwa ntchito mwakufuna kwake - chiopsezo chakutuluka kwa magazi chikuwonjezereka.
Dzinalo Losayenerana
Sulodexide
ATX
B01AB11 Sulodexide
Wessel Douai F 600 ndi gulu la mankhwala omwe ali ndi gawo limodzi.
Kutulutsa mafomu ndi kapangidwe kake
Chofunikira kwambiri ndi ntchito ya anticoagulant - thunthu sulodexide. Mankhwalawa amapangidwa mwa mawonekedwe okhazikika komanso amadzimadzi. Zina zomwe zimapangidwa ndi kapisozi:
- sodium lauryl sarcosinate;
- triglycerides;
- silicon dioxide colloidal.
Ma Shell:
- glycerol;
- gelatin;
- sodium ethyl paraoxybenzoate;
- mafuta oxide ofiira;
- sodium propyl paraoxybenzoate;
- titanium dioxide.
Kuzungulira kwa gawo lalikulu mu 1 ampoule ndi 600 LU. Amapezeka mu mawonekedwe a yankho la jakisoni kudzera m'mitsempha ndi m'mitsempha.
Kuzungulira kwa gawo lalikulu mu 1 ampoule ndi 600 LU. Kukonzekera kumalingaliridwa ndi mlingo wa chinthu monga mawonekedwe a njira yothandizira jakisoni kudzera m'mitsempha ndi m'mitsempha. Komabe, pali mtundu wina: kapisozi 1 kali ndi 250 LU ya sodeodexide. Zigawo zazing'ono zomwe zimapangidwa ndi yankho:
- sodium chloride (0.9%);
- madzi a jakisoni.
Mankhwala okhazikika amaperekedwa m'matumba a 25 ma PC. Phukusili lili ndi matuza awiri. Yankho likhoza kugulidwa mu ampoules a 2 ml. Chiwerengero chawo chonse mu phukusi ndi 10 ma PC.
Zotsatira za pharmacological
Chosakaniza chophatikizika chimapezeka kuchokera mthupi la nkhumba. Gwero lake ndi zomwe zimapezeka mu mucous membrane wa m'matumbo aang'ono. Zotsatira zake ndimapangidwe achilengedwe okhala ndi glycosaminoglycans: daltone, yomwe imafanana ndi ochepa maselo kulemera kwa heparin ndi dermatan sulfate.
Mankhwala ndi anticoagulant amene amadziwika ndi mwachindunji. Izi zikutanthauza kuti chifukwa chake, ntchito ya thrombin ndi zinthu zophatikizika ndimwazi zimachepa. Zotsatira zake zimakhala zotsatira za antithrombotic. Zina:
- profibrinolytic;
- angioprotective.
Mothandizidwa ndi sulodexide, mafashoni amwazi amapangidwa kukhala osiyana siyana, mawonekedwe ake a rheological amakhala bwino.
Kuthekera koponderezera kwa X-factor, kumapangitsanso kupanga kwa prostacyclin, ndikuchepetsa kuchuluka kwa fibrinogen m'madzi a m'magazi kumathandizanso kuchepetsa kuchuluka kwa kuphatikizira kwa magazi. Nthawi yomweyo, mulingo wa minofu ya plasminogen activator imasinthira m'mwamba, zomwe zimachitika chifukwa chakuchepa kwa kuchuluka kwa zoletsa zinthu izi.
Kuphatikiza apo, kubwezeretsa kapangidwe ka malinga a mitsempha yamagazi kumadziwika, pomwe iwo akugwira ntchito bwino. Mothandizidwa ndi sulodexide, mafashoni amwazi amapangidwa kukhala osiyana siyana, mawonekedwe ake a rheological amakhala bwino. Ichi ndi chifukwa kuchepa kwa ndende ya triglycerides.
Chida chomwe agwiritsidwacho chikuthandizira kuchepa kwamphamvu kwa njira ya kukula kwa minofu chifukwa chakuchulukana kwambiri kwa maselo. Nthawi yomweyo, kuchepa kwa makulidwe apansi apansi ndi kuchepa kwapang'onopang'ono pakupanga matrix a extracellular kumadziwika. Chifukwa cha njirazi, matendawa amakhala bwino ndi matenda a shuga.
Pharmacokinetics
Mankhwalawa amalowetsedwa ndi maselo amkati mwa ziwiya. Njira yolerera imapezeka m'matumbo. Katundu wamkulu mu chiwindi ndi impso amasinthidwa. Pankhaniyi, njira yowonongeka siyimachitika, yomwe imasiyanitsa woganiza ndi mankhwala okhala ndi heparin. Ndi kuwonongedwa, kuchepa kwa ntchito ya antithrombotic kumachitika, pomwe chimbudzi cha zinthu zazikulu kuchokera mthupi ndichulukirachulukira. Popeza kuti masinthidwe a sulodexide njirayi samakhazikika, nthawi yowonjezera magazi imawonjezeka.
Pambuyo pa tsiku limodzi, 50% ya chinthucho imapezeka mkodzo. Pambuyo masiku 2 - 67%.
Pambuyo makonzedwe, yogwira mankhwala amachotsedwa pasanathe maola 4. Sulodexide imagawidwa m'thupi lonse. Amawonetsedwa pang'onopang'ono. Pambuyo pa tsiku limodzi, 50% ya chinthucho imapezeka mkodzo. Pambuyo masiku 2 - 67%.
Zizindikiro zogwiritsidwa ntchito
Mankhwala omwe amafunsidwa amaperekedwa mu milandu ingapo:
- kuphwanya kwamitsempha yamagazi motsutsana ndi vuto la vuto lamanjenje, lomwe limawonetsedwa ndi ma spasms, paresis, ngati pali chiopsezo cha thrombosis;
- kuwonongeka kwa kufalikira kwa ziwalo, makamaka ndi kukulitsa ischemia (ndi kuchulukitsa komanso panthawi yochira);
- dyscircular encephalopathy, limodzi ndi kuwonongeka kwamitsempha muubongo, izi zitha kukhala chifukwa cha kuchepa kwa mtima, matenda a shuga, matenda oopsa kapena kusintha kwa mitsempha;
- zotupa za zotumphukira mitsempha, momwe lumen ndi patency zimachepa;
- kuthamanga kwa magazi, mitsempha yotupa;
- matenda omwe amayimira mitundu yosiyanasiyana ya microangiopathy: neuropathy, nephropathy, retinopathy, kuphatikizapo omwe adayamba motsutsana ndi maziko a matenda osokoneza bongo (martitopathy, diabetesic foot syndrome, etc.);
- mitundu yosiyanasiyana ya ma cell omwe amatsatana ndi kutupa kwa khoma lamitsempha komanso kuchepa kwa lumen yake chifukwa cha magazi;
- thrombophilic zinthu;
- mankhwalawa heparin-anachititsa thrombocytopenia wa thrombotic chikhalidwe.
Contraindication
Ubwino wa mankhwalawa umaphatikizapo kuchuluka kochepetsedwa. Ndi zoletsedwa kugwiritsa ntchito mwanjira ngati izi:
- zochita za munthu zosavomerezeka;
- diathesis yotsatana ndi kukha magazi (kutulutsa magazi kunja kwa chotengera) ndi matenda ena omwe amachepetsa mphamvu ya magazi.
Ndi chisamaliro
Ndi matenda a impso ndi chiwindi, mankhwalawa amagwiritsidwa ntchito moyang'aniridwa ndi dokotala. Kufunikira kumeneku kumachitika chifukwa chakuti chinthu chogwira ntchito chimadutsa mu chiwindi, ndikuthothola impso.
Momwe mungatenge Wessel Douai F 600?
Zotsatira zabwino zimaperekedwa ndi kusasinthasintha kwa mankhwalawa m'njira zosiyanasiyana: jakisoni woyamba, kenako makapisozi. Thupi limagwiritsidwa ntchito molingana ndi malangizo: zomwe zili mu 1 ampoule patsiku kapena kudzera m'mitsempha, njirayi imatha kulowa m'malo mwa dontho, pomwe mankhwalawo amadzidulira kale ndi saline (150-200 ml). Pitilizani maphunzirowa osapitilira masiku 20. Kuti mupeze zotsatira zokhazikika, bwerezani chithandizo kawiri pachaka.
Amaloledwa kugwiritsa ntchito mankhwalawa matenda a shuga.
Pamapeto pa maphunziro ndi njira yothetsera vutoli, amapitanso gawo lachiwiri - kutenga makapisozi. Kutalika kwa chithandizo ndi masiku 30-40. Pafupipafupi oyang'anira ndi 1 kapisozi kawiri pa tsiku.
Ndi matenda ashuga
Amaloledwa kugwiritsa ntchito mankhwalawa ndi matenda awa. Mlingo wake suwunenedwanso, koma muyenera kusamala, popeza odwala omwe ali ndi matenda amtundu wa 1 amatha kudwala matenda ena amkati, zomwe zimakhudza kagayidwe kazomwe amagwira ntchito.
Zotsatira zoyipa za Wessel Duet F
Popeza gawo lalikulu limakhudzana ndi kapangidwe ka magazi, pamakhala chiopsezo chosagwirizana. Mphamvu yawo komanso pafupipafupi imatsimikiziridwa ndi mkhalidwe wamthupi, kupezeka kwa matenda ena, kuopsa kwa zizindikiro. Mwachitsanzo, ndikamayambitsa chinthu chamadzimadzi, kupweteka kumawonekera, kumverera koyaka, hematoma imatha kupezeka pamalo opumira a pakhungu.
Ndi kuyambitsa kwa chinthu chamadzimadzi, mphamvu yoyaka nthawi zina imawoneka.
Matumbo
Ululu pamimba, limodzi ndi mseru, umadziwika. Kusintha kumachitika kawirikawiri.
Matupi omaliza
Chotupa chitha kuwoneka pazithunzi zakunja.
Zokhudza mphamvu pakuwongolera njira
Palibe chiopsezo chododometsa kugwira ntchito kwa ziwalo zamasomphenya, dongosolo lamitsempha kapena CCC, komanso njira zina zingapo mthupi. Chifukwa cha izi, zimaloledwa kuyendetsa magalimoto munthawi ya chithandizo.
Malangizo apadera
Munthawi yonse ya chithandizo, magawo angapo a magazi amayenera kuwunikidwa, omwe coagulogram amachitidwa. Magawo ofunikira kwambiri:
- antithrombin III;
- yodziyika tsankho thromboplastin nthawi - magwiridwe anthawi zamkati ndi zina zosavuta njira;
- magazi ndi nthawi yopuma.
Munthawi yonse ya chithandizo, magawo angapo a magazi amayenera kuwunikidwa, omwe coagulogram amachitidwa.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwala ndi contraindified mu 1 trimester. Mu trimesters 2 ndi 3, imagwiritsidwa ntchito moyang'aniridwa ndi dokotala. Pali chidziwitso chokwanira muzipatala za odwala omwe amapezeka ndi matenda a shuga nthawi yapakati (m'magawo apambuyo).
Palibe chidziwitso pakugwiritsa ntchito mankhwalawa panthawi yoyamwitsa.
Mlingo wa ana
Sikulimbikitsidwa kugwiritsa ntchito mankhwalawa pochiza odwala osakwana zaka 12. Pali zochepa zomwe zimagwiritsidwa ntchito ndi mankhwalawa pochiza achinyamata kuyambira zaka 13 mpaka 17. Pankhaniyi, malonda amalola bwino. Mankhwalawa ana a m'badwo uno, njira yomweyo imagwiritsidwa ntchito ngati akulu, koma nthawi ya chithandizo imachepetsedwa ndi 2 times.
Mankhwala ochulukirapo a Wessel Duet F
Ngati kuchuluka kwa Wessel Duo F kumagwiritsidwa ntchito pafupipafupi, chiopsezo chotaya magazi amtundu wina, kulimba kumawonjezeka. Mulingo wambiri womwe umaperekedwa, zimakhala zovuta kwambiri kuti muthane ndi zotsalazo.
Mavuto akachitika, maphunzirowo amasokonezedwa. Ngati ndi kotheka, chithandizo chimachitika kuti zithetse zizindikiro zake.
Kuchita ndi mankhwala ena
Wessel Duo F amaloledwa bwino ndi thupi pamene amagwiritsidwa ntchito ndi mankhwala ena ambiri. Komabe, kugwiritsa ntchito mankhwalawa limodzi ndi ma anticoagulants ena kumayambitsa kuwonjezeka kwa ntchito ya mankhwalawo, nthawi yomweyo, chiopsezo cha zovuta zimakulitsidwa. Ndipo muyenera kupewa kutenga ma anticoagulants amitundu yosiyanasiyana: zotsatira zachindunji kapena zosadziwika. Malangizo awa amagwira ntchito pa antiplatelet mankhwala.
Palibe choletsa kwambiri kugwiritsa ntchito nthawi yomweyo zakumwa zokhala ndi zakumwa zoledzeretsa ndi mankhwalawo.
Kuyenderana ndi mowa
Palibe choletsa kwambiri kugwiritsa ntchito nthawi yomweyo zakumwa zokhala ndi zakumwa zoledzeretsa ndi mankhwalawo. Komabe, mowa umathandizira zotsatira za anticoagulant, kuwonjezera pa chiwindi. Pachifukwa ichi, zakumwa zokhala ndi zakumwa zoledzeretsa ziyenera kupewedwa pakumwa.
Analogi
Monga cholowa m'malo, mankhwalawa amatha kugwiritsidwa ntchito m'njira zosiyanasiyana: yankho, mapiritsi, mapiritsi, lyophilisate. Zofananira:
- Angioflux;
- Fragmin;
- Enixum;
- Anfibra.
Mukamasankha mankhwala, muziganizira mitundu yosiyanasiyana ya zinthu zomwe zili mu kapangidwe kake. Kuphatikiza apo, amalabadira mtundu wa kumasulidwa, chifukwa zimatengera izi ngati kuli kofunikira kufotokozera kuchuluka kwa mankhwalawo kapena ayi.
Kupita kwina mankhwala
Mankhwala ndi gulu la mankhwala omwe mumalandira.
Kodi ndingagule popanda kulandira mankhwala?
Ayi.
Mankhwala ndi gulu la mankhwala omwe mumalandira.
Mtengo
Mtengo umasiyana kwambiri: kuyambira 1640 mpaka 3000 rubles.
Zosungidwa zamankhwala
Mlingo wovomerezeka wamtunda m'chipindacho si woposa + 30 ° ะก.
Tsiku lotha ntchito
Ndizololedwa kugwiritsa ntchito mankhwalawa kwa zaka 5 kuyambira tsiku lotulutsidwa. Kumapeto kwa nthawi ino, mphamvu ya mankhwalawa imatha kufooka kapena pamakhala zovuta zina zoyipa.
Wopanga
Alpha Wassermann S.P.A., Italy. Kuyika ndi kunyamula - Farmakor Production (Russia).
Ndemanga
Margarita, wazaka 39, Barnaul.
Mankhwalawa anathandiza kuwonongeka kwamitsempha ya bongo. Pambuyo pa maphunziro oyamba ndidawona kusintha kwabwino. Tsopano ndimalandira chithandizo kawiri pachaka molimbikitsidwa ndi dokotala. Zilibe zovuta.
Olga, wazaka 44, Saratov.
Mankhwalawa ndi okwera mtengo, koma ngofunika. Imathandizira mwachangu komanso modalirika. Ndinkatenga makapisozi nthawi ya pakati, chifukwa adazindikira kuti ali ndi mwana wosabadwayo. Mankhwalawa adapita popanda zovuta, Zizindikiro zoyipa zidachotsedwa. Ndine wokondwa ndi mankhwalawa, tsopano ndimawonetsetsa.
