Lorista 12.5 ndi mankhwala a mtima omwe amachepetsa kuthamanga kwa magazi, mosasamala kanthu za jenda ndi zaka za odwala. Imagwira ntchito kudzera mu blockade ya oligopeptide hormone angiotensin, yomwe imayambitsa vasoconstriction.
Dzinalo Losayenerana
Losartan.
ATX
Khodi ya ATX ndi C09CA01.
Lorista 12.5 ndi mankhwala a mtima omwe amachepetsa kuthamanga kwa magazi, mosasamala kanthu za jenda ndi zaka za odwala.
Kutulutsa mafomu ndi kapangidwe kake
Amapangidwa monga mapiritsi okhala ndi mafilimu okhala ndi zinthu zothandiza komanso zothandiza pazomwe zimapangidwa.
Phukusili limatha kukhala ndi mapiritsi 30, 60 kapena 90 m'matumba a zidutswa 10. Pali mlingo wa 12,5 mg, 25 mg, 50 mg ndi 100 mg.
Lorista 12.5 ili ndi 12.5 mg yogwira ntchito.
Chosakaniza chophatikizika ndi potaziyamu losartan.
Kutenga kwake kwa lactose kukanikiza mwachindunji kumathandizidwa ndi ma starches, enterosorbent, thickener, ndi zina.
Zotsatira za pharmacological
Losartan ndi angiotensin antagonist 2. Imalepheretsa zolandilira za timadzi timeneti makamaka m'mitsempha yama mtima, impso ndi ma adrenal gland, motero zimapangitsa chidwi.
Amachepetsa kukana kwathunthu mu zotumphukira ziwiya, kupanikizika kwa kufalikira; Pali diuretic kwambiri, kumawonjezera kukana zolimbitsa thupi kulephera mtima.
Odwala ochepa matenda oopsa, losartan mu tikulimbikitsidwa mlingo sichimakhudza kuchuluka kwa kusala triglycerides, cholesterol ndende, shuga.
Mankhwala amapezeka mu mawonekedwe a mapiritsi mu kanema wa mafilimu, omwe ali ndi mawonekedwe ndiwothandiza.
Pharmacokinetics
Mafuta a yogwira amapezeka msanga ndipo pambuyo pa mphindi 60-70 kuyika kwake kwambiri m'madzi am'magazi komanso kuchepa kwa angiotensin kumachitika kale. Imafalikira pomanga mapuloteni amadzi a m'magazi. Amasinthika m'chiwindi kukhala carboxylic acid.
Kupukusira kumachitika mkati mwa maola 6-9 kudzera mu impso kudzera m'matumbo ndi bile.
Zomwe zimathandiza
Awa ndi mankhwala othandizira ophatikiza matenda oopsa komanso kulephera kwa mtima.
Woikidwa pamilandu yotsatirayi:
- matenda oopsa ochepa ochepa;
- mankhwalawa matenda a impso mu akulu odwala ochepa matenda oopsa ndi mtundu 2 matenda a shuga ndi proteinuria;
- mawonekedwe osalephera a mtima olephera, pomwe ndizosatheka kugwiritsa ntchito ma othandizira ena chifukwa cha tsankho;
- kupewa sitiroko ndi kukwezedwa kwa magazi ndi kutsimikiziridwa kumanzere kwamitsempha yamagazi.
Pa kukakamizidwa kuti atenge
Amasankhidwa ngati kuthamanga kwa magazi kumachuluka, mosatengera zaka, kupatula ana osakwana zaka 6.
Contraindication
Direct contraindication ndi:
- kuthamanga kwa magazi;
- Zotsatira zoyipa zomwe zimagwiritsidwa ntchito ndi mankhwala;
- zaka mpaka zaka 6;
- kuchuluka kwa potaziyamu m'magazi;
- kuyamwa kwa shuga;
- lactose tsankho;
- kusowa kwamadzi;
- nthawi ya bere ndi kuyamwitsa.
Ndi chisamaliro
Chisamaliro makamaka chiyenera kulipidwa popereka mankhwala kwa ana ndi achinyamata osakwana zaka 18 chifukwa chodziwa zochepa zomwe zimapangitsa thupi la ana komanso kakulidwe kake.
Mosamala ndi kuyang'aniridwa ndi ogwira ntchito zachipatala, ndalama zimatengedwa panthawi yochepetsetsa yamitsempha yamafupa, pambuyo pake ndikuwonjezera impso, pakuchepa kwa aorta kapena mitral valavu, makulidwe a khoma lakumanzere kapena kumanja kwamtima, kutsekeka kwa impso, kulephera kwa mtima, matenda a mtima, matenda amitsempha. kumwa mankhwala ambiri okodzetsa.
Momwe mungatenge Lorista 12.5
Tengani pakamwa kamodzi patsiku, osayang'ana kwambiri pakudya (kale, pambuyo pa chakudya).
Makonda omwe angathe kupezeka molumikizana ndi mankhwala ena a antihypertensive.
Ndi kuthamanga kwa magazi, 50 mg imayikidwa koyamba, kenako, malinga ndi odwala ena, mlingo umawonjezereka mpaka 100 mg patsiku.
Mu matenda a chiwindi, kutengera kuuma kwawo komanso mapangidwe, mankhwalawa nthawi zina amachepetsedwa mpaka 25 mg patsiku.
Kulephera kwa mtima kosatha, poyamba perekani 12,5 mg patsiku, kenako pang'onopang'ono mpaka 150 mg tsiku lililonse, nthawi iliyonse kumawonjezera mlingo kawiri ndi sabata. Kukhazikitsidwa kwa makonzedwe oterowo kumalimbikitsidwa limodzi ndi okodzetsa ndi mtima wama glycosides.
Tengani pakamwa kamodzi patsiku, osayang'ana kwambiri pakudya (kale, pambuyo pa chakudya).
Ndi matenda ashuga
Ngati wodwala ali ndi matenda osokoneza bongo a digiri yachiwiri ndi mapuloteni ochulukirapo mu mkodzo, kuti aletse kufunika kwa kuyimba ndi zotsatira zoyipa, mlingo woyambirira wa mankhwalawo udzakhala 50 mg ndi kuwonjezeka kwa mtsogolo mpaka 100 mg patsiku, kutengera momwe angachepetse kuthamanga kwa magazi. Kulandila ndi insulin ndi mankhwala omwe amachepetsa shuga (glitazone, etc.). Amaloledwa kutenga diuretics ndi mankhwala ena a antihypertensive.
Zotsatira zoyipa
Zotsatira zoyipa zochepa zimakhala zachilengedwe. Mankhwalawa amapezeka kuti matupi athu samachitika kawirikawiri. Chifukwa chake, mtima wamtima ungayankhe ndi kuthamanga kwa mtima, mtima arrhythmias, etc.
Kusokonezeka kwamkati, kutupa kwa larynx ndi bronchi, kukokana, kupweteka kumbuyo, miyendo ndi minofu, komanso kuphwanya malire amagetsi omwe amapezeka pakhungu. Koma nthawi zambiri, mayankho ake amakhala ofooka komanso opitilira nthawi kotero kuti kusintha kapena kusintha kwa mankhwala sikofunikira.
Matumbo
Mimba imatha kuyankha kupezeka kwa losartan ndi mseru, kukhumudwa patulo, kukomoka, komanso kupweteka kwam'mimba.
Hematopoietic ziwalo
Pafupipafupi, koma pakhoza kuwonetsedwa mu mawonekedwe a kuchepa kwa magazi ndi matenda a Shenlein-Genoch.
Pakati mantha dongosolo
Mbali yamkati yamanjenje imatha kukhala ndi mavuto monga chizungulire, kufooka, mutu, kutopa, kusokonezeka kwa tulo.
Matupi omaliza
Zina zokhazokha za anaphylactic zochita ndi kwanthawi zonse zomwe zimachitika m'deralo zalembedwa.
Zokhudza mphamvu pakuwongolera njira
Mukawongolera machitidwe ake ndikuyendetsa, muyenera kusamala, popeza chizungulire ndikugona ndi kotheka. Kuchita koteroko kumadziwika ndi gawo loyamba la mankhwalawa kapena ndi mlingo waukulu.
Malangizo apadera
Odwala omwe adakumana ndi zovuta zam'mbuyomu, chiwindi kapena matenda a impso ayenera kulandira chithandizo chokhazikitsidwa ndi dokotala komanso pazifukwa zaumoyo.
Mankhwalawa sayenera kugwiritsidwa ntchito ndi odwala limodzi ndi aliskiren kapena aliskiren okhala ndi matenda a shuga.
Gwiritsani ntchito mu ukalamba
Mukakalamba, kumwa mankhwalawa sikusiyana ndi omwe achinyamata amagwiritsa ntchito.
Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Panthawi yobereka komanso yoyamwitsa, mankhwalawa sanakhazikitsidwe, ndipo mimba ikakhazikitsidwa, imathetsedwa nthawi yomweyo, chifukwa pali chiopsezo cha mwana wosabadwayo (hypoplasia yamapapu ndi chigaza, kusinthika kwa mafupa, kupatsanso impso kwa mwana wosabadwayo, etc.). Zotsatira zamakono zatsopano za mankhwala zomwe zimaperekedwa mkaka wa m'mawere sizinaphunzire, chifukwa chake, siziyenera kugwiritsidwa ntchito chifukwa chosadziwika bwino pakumachitika kwa thupi la mwana.
Mukamayamwa, mankhwalawa saikidwa mankhwala.
Kusankhidwa kwa ana a Lorista 12.5
Ana osakwana zaka zisanu ndi chimodzi samakhazikitsidwa. Paukalamba mpaka zaka 18, kugwiritsa ntchito sikulimbikitsidwa ndipo kungatheke pokhapokha ngati pali njira ina, popeza palibe maphunziro azolowera kugwiritsa ntchito mankhwala osokoneza bongo omwe ali ndi losartan pakapangidwe.
Bongo
Mlanduwo ukalandira mlingo wamphamvu kwambiri, mutha kusintha kwa matenda ochepa komanso mtima.
Kuchita ndi mankhwala ena
Imagwirizana bwino ndi hydrochlorothiazide, digoxin, warfarin, cimetidine, phenobarbital ndi ena ambiri. Mankhwala osokoneza bongo a potaziyamu osagwiritsa ntchito kukonzekera kwa potaziyamu (Triamteren, Amiloride, ndi zina) angapangitse kuwonjezeka kwa chinthuchi m'magazi. Kuphatikiza ndimankhwala osagwiritsa ntchito steroidal othandizira kuti muchepetse kutupa kumatha kuchepetsa mphamvu ya mankhwalawo.
Zowotchera zowopsa kuphatikiza ndi losartan zimabweretsa kutsika kosalamulirika kwa kupanikizika m'mitsempha.
Kulandiridwa ndi mankhwala ena a antihypertensive kungachepetse kuthamanga kwa magazi.
Mankhwala omwe amathandizira RAAS (Captopril, Lisinopril, ndi ena otero) amatha kusokoneza ntchito ya impso ndikukulitsa zomwe zili urea ndi creatinine malinga ndi magawo a labotale.
Kuyenderana ndi mowa
Popewa zosafunikira zamagetsi pamtima sizingakhale pamodzi ndi zakumwa zoledzeretsa. Kugwiritsa ntchito nthawi imodzi kumatha kubweretsa kuchepa kwambiri kwa kuthamanga kwa magazi, kuphwanya ntchito zam'mimba, chiwindi, ndi impso.
Analogi
- Angizar (India).
- Gizaar (USA).
- Cardomin-Sanovel (Turkey).
- Losartan (Israel).
- Lozarel (Switzerland).
- Lorista ND (Slovenia).
- Lozap kuphatikiza (Czech Republic).
- Erinorm (Serbia).
Miyezo ya tchuthi Lorista 12.5 kuchokera ku pharmacy
Kodi ndingagule popanda kulandira mankhwala?
Osaperekedwa popanda mankhwala a dokotala.
Mtengo wa Lorista 12.5
Mtengo umasiyanasiyana kutengera wopanga, kuchuluka kwa mapiritsi omwe ali phukusi ndi malo ogulitsa. Mtengo wamitundu - kuchokera ku 180 mpaka 160 ma ruble pachilichonse.
Zosungidwa zamankhwala
Pamalo owuma, amdima pamtunda wa kutentha osaposa 30ºº. Pewani kutali ndi ana ndi nyama.
Tsiku lotha ntchito
Sungani zaka zopitilira 2 kuchokera tsiku lopanga.
Wopanga Lorista 12.5
Imapangidwa ku Slovenia ndi kampani yopanga mankhwala JSC Krka, dd, Novo mesto. Ku Russia, kupanga kumachitika ndi KRKA-RUS LLC mumzinda wa Istra, Moscow Region.
Ndemanga za Lorista 12.5
Omvera zamtima
Arina Ivanovna, katswiri wamtima, Omsk
Mukamamwa mankhwalawa, ndikofunikira kuganizira za contraindication ndi nuances ambiri a kumwa. Ndikofunikira mosamala kwambiri kuti mukhale ndi anthu omwe ali ndi vuto la impso, osalolera kwa gawo lalikulu, omwe ali ndi matenda a mtima, pakati komanso kuyamwitsa. Ndikofunika kuchenjeza kuti kumapeto kwa maphunzirowa kumapeto kwa maphunzirowa ndikofunikira kupewa kumwa kwa nthawi yonse ya mankhwalawa ndikulanda kwa masiku 5-7 mutatha kumwa mapiritsi kuti chinthu chithe m'thupi.
Pavel Anatolyevich, katswiri wamtima, Samara
Amagwiritsidwa ntchito makamaka kuphatikiza ndi mankhwala ena, ndipo monga kudzipatula sikumawonetsa kuyeserera kwakukulu. Khalidwe lofunika lomwe ndimaona kuti ndizotheka kuteteza impso mwa odwala omwe ali ndi matenda a shuga a 2 omwe ali ndi proteinuria. Mtengo wake umakhala wokwanira, zomwe zimapangitsa kuti mankhwalawa akhale okwera mtengo pafupifupi pafupifupi magulu onse odwala.
Choyipa chake ndi embryotoxicity yapamwamba, zomwe zimapangitsa kuti zikhale zosavuta kugwiritsa ntchito nthawi yapakati.
Alexey Stepanovich, katswiri wa zamtima, Norilsk
Malinga ndi kuwunika kwa odwala, zimalekereredwa bwino, kupanikizika kumachepa pang'onopang'ono komanso modekha, koyenera achinyamata ndi okalamba.
Ndinaona zoyipa kamodzi kokha - bambo ali ndi zaka 49 anayamba kumva chizungulire, chifukwa chomwe sakanatha kuyendetsa galimoto. Pankhaniyi, mankhwalawa adasinthidwa.
Odwala
Andrey, wazaka 30, Kursk
Adamwa mapiritsi monga adanenera ndi mtima. Mlingo woyambayo unali 50 mg, kenako pang'onopang'ono unakwera mpaka 150 mg. Zimagwira bwino, kunalibe mavuto. Ndipo mtengo wake siwokwera kwambiri.
Olga, wazaka 25, Aktyubinsk
Anapatsidwa amayi kuti ateteze impso, chifukwa ali ndi matenda a shuga. Malinga ndikuwona, amayi adamva bwino: kupanikizika kumakhala kosakhazikika. Ndipo kuwunika pakuwunikira, kuchuluka kwa mapuloteni mumkodzo kunachepa. Mankhwalawa adapita mwangwiro ndipo osakhala ndi zotsatirapo zoyipa zakumwa nawo adazindikira.
