Pamavuto a kuthamanga kwa magazi, madokotala amatipatsa mankhwala oyenera kuti athandizike. Nthawi zambiri, Diroton ndi Lisinopril amalembedwa chifukwa chaichi. Mankhwalawa ndi ofanana m'njira zambiri, koma pali zosiyana. Simungathe kuwatenga osalandira mankhwala a dokotala.
Khalidwe la Diroton
Mankhwalawa ndi othandizira a ACE omwe amachepetsa kuthamanga kwa magazi ndi kuchepetsa mitsempha ya magazi. Zomwe zimagwiritsidwa ntchito ndi lisinopril, zomwe zimachepetsa kuchuluka kwa aldosterone ndi angiotensin mu plasma. Zotsatira zake, pali kuchepa kwa zotumphukira zamitsempha komanso kukwera kwa kuchuluka kwa magazi kudutsa pamtima pamphindi. Izi sizimayambitsa vuto la mtima.
Pamavuto a kuthamanga kwa magazi, madokotala amatipatsa mankhwala oyenera kuti athandizike. Nthawi zambiri, Diroton ndi Lisinopril amalembedwa chifukwa chaichi.
Kutulutsa mawonekedwe - mapiritsi. Kusunga kwambiri kwa lisinopril m'magazi kumachitika pambuyo pa maola 6-7.
Zisonyezero zogwiritsira ntchito Diroton:
- matenda oopsa;
- pachimake myocardial infarction;
- matenda ashuga nephropathy;
- kulephera kwa mtima kosatha.
Ndi zoletsedwa kumwa mankhwala ngati:
- tsankho kwa zigawo zikuluzikulu;
- Kuchepetsa lumen ya mitsempha ya impso;
- chibadwire chakutsogolo kwa edema ya Quincke;
- kusintha kwa magawo amwazi wamagazi;
- stenosis ya msempha orion;
- aldosteronism yoyamba;
- zaka mpaka 16.
Diroton amaletsedwa nthawi yobala mwana, chifukwa zigawo zake zimalowa mkati mwa placenta. Kugwiritsa ntchito zoletsa za ACE mu trimester yomaliza kumakhudza mwana wosabadwayo, zomwe zimatsogolera ku imfa ya fetal. Mankhwala satengedwa pa mkaka wa m`mawere.
Kugwiritsa ntchito mankhwalawa kumabweretsa zotsatirapo zosiyanasiyana zoyipa zamagetsi ambiri:
- kupuma: bronchospasm, kufupika kwa mpweya, chifuwa popanda sputum;
- mtima: kulowetsedwa kwa myocardial, kupweteka kwa sternum, kuchepa kwa mtima, kuchuluka kwa mtima;
- urogenital: uremia, utachepa kugonana poyendetsa, matenda aimpso;
- kuzungulira: m'munsi hemoglobin, kuchepa magazi, neutropenia;
- pakati mantha: kukokana, kutopa kwambiri, kugona, kusinthasintha kwa zochitika, kulephera kuyang'ana kwambiri chilichonse;
- kupukusa m'mimba: kutupa kwa chifuwa cham'mimba, chiwindi, kulawa kwamkati, kutsegula m'mimba, kutsutsana kwamapweteka pamimba, pakamwa owuma, kusanza;
- Khungu: kuyabwa, dazi, zotupa, thukuta kwambiri.
Wopanga mankhwalawa ndi a George Richter OJSC, Budapest, Hungary.
Chikhalidwe cha Lisinopril
Lisinopril ndi choletsa ACE. Gawo lake lalikulu ndi lisinopril (mwanjira ya dihydrate). Mankhwalawa amachepetsa kuthamanga kwa magazi, kukulitsa mitsempha, kukonza myocardial ntchito, ndikuchotsa mchere wa sodium. Ndi kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, makhoma a myocardium ndi mitsempha yamagazi amayamba kuzilala, magazi amatuluka. Mankhwala amamasulidwa ngati mapiritsi.
Lisinopril ali ndi zizindikiro zogwiritsidwa ntchito ngati:
- pachimake myocardial infarction;
- matenda ashuga nephropathy;
- kulephera kwa mtima;
- kuthamanga kwa magazi.
Mankhwalawa amalepheretsedwa monga:
- mitral stenosis;
- hypertrophic cardiomyopathy;
- hemodynamic aortic stenosis;
- idiopathic angioedema;
- tsankho ndi kuchepa kwa lactose;
- tsankho kwa zinthu zomwe zimapanga mankhwala;
- zaka mpaka 18;
- mimba ndi mkaka wa m`mawere.
Chithandizo nthawi zambiri limodzi ndi chitukuko cha hyperkalemia. Zomwe zimayambitsa kupezeka kwake zimaphatikizapo: matenda a shuga, azaka zopitilira 70, kusokonekera kwa impso.
Lisinopril amachepetsa kuthamanga kwa magazi, koma imatha kuyambitsa mavuto ambiri. Itha kukhala:
- kutsokomola ndi sputum yosagwirizana, kutopa, mseru, chizungulire, kutsegula m'mimba, kupweteka mutu;
- palpitations, kupweteka kwa sternum, tachycardia, myocardial infarction;
- kuchepa chidwi, minofu kukokana mu miyendo ndi mikono;
- dyspnea, bronchospasm;
- kutupa kwa kapamba ndi chiwindi, jaundice, kusintha kukoma, kupweteka pamimba, pakamwa youma, matenda a anorexia;
- khungu loyenda, kupukusa kwambiri, thukuta;
- uremia, pachimake aimpso kulephera, oliguria, anuria, mkhutu aimpso ntchito;
- nyamakazi, myalgia, vasculitis.
Kuchokera pa hemopoietic dongosolo, kuchepa magazi, thrombocytopenia kumachitika. Chiwopsezo chimayamba ngati mawonekedwe a angioedema a malekezero ndi anaphylactic edema ya larynx. Nthawi zambiri pamakhala zotupa pakhungu, urticaria, malungo, leukocytosis.
Ndi munthawi yomweyo kugwiritsa ntchito lisinopril ndi sodium aurothiomalate, zizindikiro zotsatirazi zingachitike: ochepa matenda oopsa, nseru, redness la khungu la nkhope. Kumwa mankhwalawa kumatanthauza kupatula mphamvu zolimbitsa thupi, chifukwa madzi am'mimba amatha. Lisinopril osakanikirana ndi okodzetsa amachotsa potaziyamu m'thupi.
Wopanga mankhwalawa ndi CJSC Skopinsky Pharm.zavod, Russia.
Kuyerekezera kwa Diroton ndi Lisinopril
Mankhwalawa onse ali ndi zofanana, koma pali kusiyana pakati pawo.
Zofala
Diroton ndi Lisinopril ndi mankhwala a antihypertensive ndipo ali ndi gawo lomweli - lisinopril. Amawerengera matenda oopsa, chifukwa ali ndi zotsatira zake. Amapezeka piritsi. Kuchuluka kwakukulu mukamazitenga kumawonedwa pakatha milungu iwiri.
Mankhwala sayenera kumwedwa panthawi yoyembekezera komanso poyamwitsa. Mukamazitenga, mavuto ambiri amatha.
Kodi pali kusiyana kotani?
Kusiyana kwakukulu pakati pa Diroton ndi Lisinopril ndikuti mankhwala oyamba sangatengedwe ndi odwala omwe ali ndi cholowa chokhala ndi edema ya Quincke, ndipo chachiwiri - kwa odwala omwe samalekerera lactose. Pali kusiyana pamankhwala. Diroton amayenera kumwedwa ndi 10 mg kamodzi patsiku, ndipo Lisinopril - 5 mg yokha. Ali ndi opanga osiyanasiyana.
Zomwe zimakhala zotsika mtengo
Mitengo ya mankhwala ndizotsatirazi:
- Diroton - ma ruble 360.
- Lisinopril - ma ruble 101.
Zomwe zili bwino - Diroton kapena Lisinopril
Mukamasankha mankhwala omwe ali bwino - Diroton kapena Lisinopril, adokotala amatenga malingaliro ambiri:
- matenda odwala;
- contraindication
- mtengo wa mankhwalawo.
Ndemanga za akatswiri azachipatala
Olga, wamtima wazaka 56, ku Moscow: "Diroton nthawi zambiri amathandizidwa ndi odwala omwe ali ndi vuto la mtima komanso kuthamanga kwa magazi. Ndimasankha mlingo wautali. Kutalika kwa chithandizo kumatengera zomwe zachitika.
Sergey, Therapist, wazaka 44, Syzran: "Nthawi zambiri ndimapereka mankhwala a Lisinopril kwa odwala omwe ali ndi matenda oopsa. Amachepetsa kuthamanga kwa magazi. Koma ku monotherapy, mankhwalawa sathandiza aliyense, chifukwa chake ayenera kuphatikizidwa ndi mankhwala ena."
Ndemanga za odwala za Diroton ndi Lisinopril
Vera, wazaka 44, Omsk: "Kupanikizika kunayamba kuchuluka pafupipafupi mpaka zaka 40. Mtengo wapamwamba unafika pa 150. Dokotala adamuuza Lisinopril. Zotsatira zake sizimachitika mwachangu monga tikufuna. Kukakamiza kuchokera ku 150 kunatsikira kufika pa 120 pambuyo pa maola 8 okha. zopindulitsa - mukapitiliza, zimapangitsa kuti ndikhale ndi nkhawa. Ndikufuna kunena kuti kugona ndikutopa chifukwa chotsatira zoyipa. Ndiyenera kupirira nazo, chifukwa mankhwalawa sayenera kutha ndi kuledzera. "
Oksana, wazaka 52, Minsk: "Ndikumutenga ngati Diroton wolembedwa ndi dokotala chifukwa cha kulephera kwa mtima. Poyerekeza ndi mankhwala ena, Diroton ali ndi zovuta zingapo: mkamwa youma, chizungulire, mseru. Koma zotsatira zake ndi zachangu. kuchepetsa kukakamiza mu ola limodzi. "
