Deoxinate ndi wa gulu la othandizira ma immunomodulating. Mankhwalawa amapangidwa mwa njira yothetsera jakisoni wa intramuscularly komanso subcutaneously, komanso mawonekedwe a yankho lagwiritsidwa ntchito kunja. Mankhwala amakupatsani mwayi wowonjezera minyewa yakumadera a necrotic, kuonjezera kuchuluka kwa magazi m'munda wa ischemia ndikuwonjezera kuyankha kwa chitetezo mthupi mwa ma virus ndi bakiteriya.
Dzinalo Losayenerana
Sodium deoxyribonucleate.
ATX
L03AX.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapangidwa mwa njira yothetsera jakisoni ndikugwiritsa ntchito kunja. 1 ml yotsirizira ili ndi 0,0025 g yogwira ntchito - sodium deoxyribonucleate yopangidwa kuchokera mkaka wa sturgeon. Njira yothetsera ntchito yakumaloko imayikidwa mumbale za galasi 50 ml. Kugulitsidwa zidutswa mu makatoni.
Mankhwalawa amapangidwa mwa njira yothetsera jakisoni ndikugwiritsa ntchito kunja.
Mu 1 ml ya jakisoni yankho ndi 5 mg ya mankhwala othandizira. Makatoniwo amakhala ndi magalasi 10 a 5 ml iliyonse ndi mpeni wowatsegulira.
Zotsatira za pharmacological
Mankhwala amathandizira kugwira ntchito kwa ma cellular komanso amanyazi poyankha chitetezo cha m'thupi. Chifukwa chakuchita bwino kwa njira yochizira pamthupi, imakhala ndi antibacterial, antifungal and antiviral effect. Zinthu zothandizazi zimatha kuwonjezera kukana kwa ma radiation komanso zimathandizanso kukonzanso minofu.
Mankhwala bwino mkhalidwe wa mtima endothelium mu pathologies a mtima dongosolo. Iwo ali odana ndi kutupa kwenikweni, amatenga nawo kuponderezedwa kwa chotupa kukula. Sodium deoxyribonucleate imaletsa magazi kuundana. The yogwira pophika zimakhudzana ndi hematopoiesis, zimabweretsa kufanana boma kuchuluka kwamaselo a magazi:
- maselo oyera;
- mapulateleti;
- phagocytes;
- monocytes;
- granulocytes.
Pulogalamu yogwira imagwira mu hypoplastic anemia yoyambitsidwa ndi radiation kapena chemotherapy motsutsana ndi maziko a metastasis a neoplasms yoyipa.
Mankhwala Deoxinate ali ndi antibacterial, antifungal komanso sapha mavairasi oyambitsa.
Ngati sodium deoxyribonucleate yapukutidwa mu mnofu mkati mwa tsiku limodzi mutalandira ma radiation a ionizing radiation, mankhwalawa amathandizira kukulitsa kulekerera kwa matenda a radiation mu II ndi III zovuta ndikuthandizira kubwezeretsanso maselo a tsinde mu msana ndi kufinya. Pankhaniyi, kuthamangitsidwa kwa hematopoiesis a myeloid ndi mitundu ya N-lymphoid imawonedwa. Kuthekera kwa kuchira kwabwino kwa thupi pambuyo poti chiwonetserochi chikuwonjezereka.
M'mayesero azachipatala, ntchito ya leukopoiesis imawonjezeka pambuyo pobayira limodzi mu mnofu wa odwala omwe ali ndi vuto loopsa la kuchepa kwa plasma ya leukocytes ya III ndi zovuta za IV. Gulu lowongolera lidaphatikizapo odzipereka omwe ali ndi febrile neutropenia, omwe adakwiya ndi chemotherapy ndi mankhwala a anticancer, ndikutsatiridwa ndi radiation.
Odwala adawonetsa kuwonjezeka kwa plasma ndende ya granulocytes ndi maulendo 8 mu zotumphukira. Nthawi yomweyo, kuchuluka kwa ma lymphocyte kunachuluka, kuchuluka kwaminyewa yamagazi ofiira ndikubwezeretsanso maziko a thrombocytopenia kuchokera ku I kupita ku IV yokhazikika kwa etiology yofanana.
Mankhwala kumawonjezera kukana zolimbitsa thupi ndipo amathandizira kupewa kukula kwa zopweteka m'matumbo a miyendo motsutsana ndi kuwonongeka kwa ischemic kumitsempha yam'munsi, yomwe imayambitsidwa ndi atherossteosis kapena matenda ashuga. Mankhwalawa amalepheretsa kuchepa kwa kutentha kwamapazi chifukwa chakuyenda bwino kwa magazi kupita ku ziwalo za m'munsi.
Sodium deoxyribonucleate imathandizira kusinthika kwa minofu m'magazi a matenda ashuga, gangrene, trophic zilonda. Nthawi zina, chinthu chogwira ntchito chimayambitsa kukana kwa madera a necrotic, phalanges, potero kupewa opaleshoni.
Mu matenda a mtima, mankhwalawa amagwiritsidwa ntchito pokonzanso magwiridwe antchito a myocardium ndi ziwiya zina za m'magazi, kuonjezera kukana ntchito zolimbitsa thupi.
Mankhwalawa amathandizira kuthamangitsa kubwezeretsa kwa mucous nembanemba okhala ndi zilonda zam'mimba komanso duodenum, komwe kumayambitsa kukula kwa Helicobacter pylori. Zogwira pophika zimawonjezera mwayi wazotsatira zabwino pakufalikira kwa ziwalo ndi minofu.
Pharmacokinetics
Ikagwiritsidwa ntchito timitu tambiri, timene timagwira ntchito timayenderera m'matumbo ndi mucous kumayambira yamafuta, pomwe timalimbikitsanso chitetezo cha m'thupi komanso minyewa. Kuchuluka kwa plasma ndende ya deoxyribonucleate kumatheka mkati mwa ola limodzi. Zinthu zamankhwala zimachoka m'thupi kudzera munkodzo masana.
Zizindikiro zogwiritsidwa ntchito
Mankhwala amagwiritsidwa ntchito motere:
- ndi kuchepa kwa leukocytes ndi mapulateleti omwe amayamba chifukwa cha kuphatikiza kwa mankhwala a antitumor kapena cytostatics;
- monga njira yoletsa kukakamiza kwa myeloid hematopoiesis isanafike chemotherapy, munthawi ya chithandizo ndikutsiriza mankhwala ndi antitumor othandizira;
- kusinthitsa zochitika pambuyo povomerezeka ndi ionizing radiation ndi II radiation II, III digiri yovuta;
- zochizira stomatitis, zilonda zam'mimba ndi duodenum, trophic zilonda;
- imathandizira kukonzanso kwa purulent njira ndi sepsis, kuwotcha, kutseguka mabala osachiritsa omwe ali ndi matenda a staphylococcal;
- kukonza magazi kuti azikhala ndi ischemic myocardium ndi mitsempha yamagazi m'munsi m'munsi;
- pokonza thupi lachiberekero;
- zochizira zotupa njira;
- ndi kusabereka kwamtundu woyambira chifukwa cha matenda.
Njira yothetsera ntchito zakunja ndi zakomweko zitha kugwiritsidwa ntchito ngati prophylaxis komanso chithandizo chothandizira kupuma kwa thirakiti la kupuma kwapamwamba (kupanikizana kwammphuno, sinusitis), kuthetsa ma hemorrhoidal node ndikuthandizira kubwezeretsanso kwa mucous membranes omwe samachiritsa chifukwa cha njira ya bacteria.
Contraindication
Mankhwala sayenera kugwiritsidwa ntchito kwa anthu omwe akuyembekezeka kukula kwa thupi lawo siligwirizana ndi zigawo za deoxynate.
Momwe mungatengere Desoxinate
Njira yothetsera jakisoni ikhoza kuikidwa mosadukiza kapena m'mitsempha. Kwa odwala akuluakulu, mlingo woyenera wa tsiku lililonse ndi 5-15 ml ya yankho la 0.5%. Jekeseni minofu iyenera kuyikidwa pang'onopang'ono kwa mphindi 1-2. The pakati pakati jakisoni pafupifupi 24-72 maola.
Mlingo wothandizila kuthana ndi mayankho a kunja ndi kwa makolo umakhazikika malinga ndi kuwunika kwa matenda omwe adokotala ali nawo ndi mtundu wa njira ya matenda.
| Njira yogwiritsira ntchito | Mtundu wa pathological process | Chithandizo cha mankhwala |
| Kholo | Coronary matenda a mtima ndi mtima ischemia m'malo otsika | 5-10 jakisoni / m iyenera kuyikika ndi masiku atatu. Mlingo wambiri wa mankhwala ndi 375-750 mg. |
| Chithandizo cha kusabereka komanso kusabala mphamvu chifukwa cha matenda opatsirana | Jakisoni 10 amaperekedwa pakadutsa maola 24 mpaka 48. Mlingo wathunthu wa nthawi yonse ya chithandizo ndi 750 mg. | |
| Zilonda zam'mimba zam'mimba ndi duodenum | 5 jakisoni amaikidwa pakatikati pa masiku awiri. Mlingo wa maphunziro onse a 375 mg. | |
| Kulimbikitsa leukopoiesis ndi mankhwala a pachimake radiation pharyngeal syndrome | V / m maola 48-96 aliwonse pa 75 mg. Mlingo wa maphunzirowa ndi 150-750 mg, wogawidwa pawiri. Mukakwiya, mulingo umakwera mpaka 375-750 mg. Pochita mobwerezabwereza maphunziro a chemotherapy kapena radiation chithandizo, kuperekanso kwachiwiri ndikofunikira. Mankhwalawa pachimake radiation, ndikofunikira kuyambitsa mankhwalawa patangotha tsiku limodzi mutatha njira. | |
| Kunja | Mabala osachiritsika a nthawi yayitali komanso zotupa zina zapakhungu | Chithandizo ndi ntchito ndi kuchepetsedwa njira ya 0,25% ndende. Zovala zimagwiritsidwa ntchito katatu patsiku. Ngati ndi kotheka, chithandizo chimaphatikizidwa ndi jakisoni wa mu mnofu. |
| Kuwonongeka kwa mucous nembanemba wamkamwa | Muzimutsuka pakamwa ndi yankho la 0,25%, ndikutsatira kumeza 5-20 ml yankho. Masetsedwe amachitika 4 mpaka 6 pa tsiku. | |
| Vaginitis, kumatako fisi | Ndi kutukusira kwa mucous nembanemba wa nyini kapena veva, ndikofunikira kuti nyowetsa swab mu yankho ndikuwayika mu chitseko cha kumaliseche. Kuwongolera kwa miyambo kumachitika pogwiritsa ntchito ma microclysters odzazidwa ndi 10-50 ml ya yankho. Njira ya mankhwalawa nthawi zonse zimasiyanasiyana kuyambira masiku 5 mpaka 10 mpaka pamene chisonyezo cham'mimba chimatha. | |
| Matenda a rhinitis, sinusitis, phlebitis, kupewa kwa ARVI | Mu gawo lililonse la mphuno kukhazikitsa 2-3 kumatsikira katatu patsiku. Kuti muthane ndi matenda oyambitsidwa ndi ma virus, muyenera kudontha ma dontha atatu nthawi iliyonse pamphindi 60. | |
| Kutupa kwa paranasal sinuses, nasopharyngitis | 3-6 imatsika m'mphuno aliyense wamphongo 3-6 patsiku. | |
| Kutupa kwam'mimba, zilonda zam'misewu | Kugwiritsa ntchito kunja 3-4 kumatsika kasanu ndi kamodzi patsiku. Njira ya mankhwala ndi miyezi 6. |
Ndi matenda ashuga
Odwala omwe ali ndi vuto la mtundu woyamba wa 2 ndi mtundu wa 2 ayenera kuyang'anitsitsa kuchuluka kwa shuga m'magazi nthawi yonse ya mankhwala. Izi ndizofunikira kuti tikonzeke kuchuluka kwa hypoglycemia munthawi komanso kusintha kwa kuchuluka kwa ma hypoglycemic othandizira.
Odwala omwe ali ndi vuto la mtundu woyamba wa 2 ndi mtundu wa 2 ayenera kuyang'anitsitsa kuchuluka kwa shuga m'magazi nthawi yonse ya mankhwala.
Zotsatira zoyipa za Deoxinate
Kukula kwakanthawi kutentha kwa thupi kukhala wocheperachepera kapena wocheperako mphamvu kumatha kukhala kwa maola 2-4 pambuyo pa maola atatu kapena tsiku limodzi mutangopereka mankhwala. Nthawi zina, zimachitika mu jakisoni jakisoni, limodzi ndi kufiira, kuwawa, kapena kutupa. Zochita zimachitika pazokha. Odwala omwe ali ndi chiwopsezo, zotupa zamkati mwa mawonekedwe a zotupa pakhungu zimatha, ndikulimbana kwambiri, kukokana kwa anaphylactic kapena edema ya Quincke.
Zokhudza mphamvu pakuwongolera njira
Mankhwala samakhudza kuthamanga kwa zimachitika, kuzindikira ntchito ndi chidwi. Chifukwa chake, munthawi yamankhwala othandizira, amaloledwa kuyendetsa galimoto kapena njira zovuta, ngati mkhalidwe wa wodwalayo umalola kupsinjika kwamalingaliro ndi thupi.
Malangizo apadera
Mtsempha wamagulu osokoneza bongo ndi oletsedwa. Njira yothetsera vutoli siyothandiza kwenikweni mu njira ya pathological, yokhala ndi zotupa zakuya zamkati mwa dera lalikulu la IV digiri yoopsa.
Mankhwalawa amagwiritsidwa ntchito ngati leukopenia, ngati kuchuluka kwa leukocytes ndi ochepera 3,500 pa 1 μl, ndi thrombocytopenia ndi mitengo yotsika ndi 150,000 pa 1 μl.
Gwiritsani ntchito mu ukalamba
Anthu azaka zopitilira zaka 60 sayenera kusintha mtundu wa zochizira.
Kupatsa ana
Kwa ana mpaka miyezi 24, mlingo woyenera ndi 0,5 ml ya yankho la mu mnofu kapena wamkati, kuyambira zaka 2 mpaka 10, muyenera kuwonjezera kuchuluka kwa 0,5 ml pachaka chilichonse cha moyo, kuyambira zaka 10 mpaka 18, mulingo woyenera wa munthu wamkulu umagwiritsidwa ntchito.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mankhwalawa ali contraindified mwa amayi apakati ndi mkaka wa m`mawere chifukwa cha kusowa deta pa zotsatira za mankhwala pa kukula ndi chitukuko cha thupi la munthu embryonic ndi postembryonic nthawi ya moyo.
The ntchito aimpso kuwonongeka
Deoxinate yothetsera imaletsedwa kugwiritsa ntchito kwambiri kulephera kwaimpso.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Anthu omwe ali ndi vuto losayenera la chiwindi amalimbikitsidwa kuti asamale.
Mankhwala osokoneza bongo a Deoxenate
Ndi jakisoni imodzi kapena kugwiritsa ntchito mlingo waukulu wa mankhwalawa, palibe milandu yambiri yolembedwa. Zotsatira zoyipa kapena kufalikira kwawo.
Kuchita ndi mankhwala ena
Njira yothetsera kugwiritsidwa ntchito sigwirizana ndi mafuta okhazikika pamafuta amafuta komanso ndi hydrogen peroxide. Mankhwala amatha kuonjezera mphamvu ya antiviral ndi antibacterial, amachepetsa nthawi yokhala ndiwofatsa. Sodium deoxyribonucleate imapititsa patsogolo zotsatira za antitumor mankhwala othandizira ndi ma cytostatics.
Mankhwala amatha kuonjezera mphamvu ya ma antiviral ndi antibacterial.
Kuyenderana ndi mowa
Pa chithandizo ndi Deoxinate, ndizoletsedwa kumwa mowa kapena kugwiritsa ntchito mankhwala okhala ndi ethanol. Ethanol amatha kufooketsa mankhwalawa chifukwa cha mankhwalawa, chifukwa chopinga cha mafupa a hematopoiesis ndikuwonjezera chikhalidwe cha wodwalayo.
Analogi
Malonda a mankhwalawa akuphatikizapo:
- Derinat;
- Sodium deoxyribonucleate;
- Penogen;
- Ferrovir
Kupita kwina mankhwala
Mankhwalawa amaperekedwa mosiyanasiyana malinga ndi mankhwala omwe mwalandira.
Kodi ndingagule popanda kulandira mankhwala?
Ngati angagwiritsidwe ntchito molakwika, mankhwalawo amatha kubweretsanso mavuto pakakhala kuti palibe zowonetsa zachipatala mwachindunji. Chifukwa chake, kugulitsa kwaulere m'misika yovomerezeka kumaletsedwa.
Mtengo
Mtengo wapakati wa mankhwala ndi pafupifupi 300-500 rubles.
Zosungidwa zamankhwala
Ndikofunikira kusunga yankho pa kutentha kwa + 5 ... + 10 ° C m'malo otetezedwa ku cheza cha ultraviolet, chokhala ndi chinyezi chocheperako.
Tsiku lotha ntchito
Zaka zitatu
Zotsatira zamankhwala osokoneza bongo zimaphatikizapo mankhwala a Derinat.
Wopanga
FSUE SPC Pharmzashchita FMBA, Russia.
Ndemanga
Ekaterina Belyaeva, wazaka 37, Yekaterinburg
Dokotala wa ana adapereka njira yothetsera vuto la kupakika mankhwala opha ziwindi ndi kutsokomola. Kuphatikiza apo, zinali zofunikira kumwa mankhwala a antipyretic, koma kokha pamtunda wotentha kuposa 38,5 ° C. Adotolo adati kutentha kumatha kutuluka kwakanthawi kuchokera ku yankho. Zinali zofunika kutsuka m'mphuno wamkati maola 2 aliwonse ndi madontho 3-5 a Deoxinate, atatha kukonza vutoli, kuchotsekerako kumachepetsedwa mpaka katatu patsiku. Mwanayo anachira pambuyo masiku 5. Panalibe zoyipa.
Emilia Ponomareva, wazaka 45, Moscow
Ndakumanapo ndi Deoxinat kangapo, chifukwa chake ndimawona kuti ndi yothandiza. Mwamuna ndi mwana wakeyo adagwiritsa ntchito yankho la kutsuka mphuno ndi rhinitis. Kusokonezeka kwa amuna anga kunali kofulumira - masiku awiri, mwana anali wodwala pafupifupi sabata limodzi. Mwina ndi chitetezo chokwanira. Ndikutikita mu minofu ya ng'ombe pakulimbikitsidwa ndi dotolo monga njira yotukutsira ma microcirculation. Sindinamve zolemetsa zilizonse kwa maola 3-5, miyendo yanga inasiya kutupa. Ndinkayesanso kuthandizidwa ndimankhwala ena, koma mphamvu zake zidachepa.
