Mankhwala a Hypoglycemic amapatsidwa shuga. Mankhwala a insulin amakulolani kusintha shuga. Gulu la mankhwalawa limaphatikizapo Insuman Rapid GT.
Dzinalo Losayenerana
Soluble insulin (umisiri wa majini a anthu).
ATX
A10AB01.
Kutulutsa mafomu ndi kapangidwe kake
Njira yothetsera vutoli imapezeka m'mbale kapena ma cartridge. Kuyika ndi jekeseni ya solostar yotayikira ikuchitika.
Chithandizo chophatikizika m'madzi ndi insulin yaumunthu. Kuphatikizika kwa yankho ndi 3.571 mg, kapena 100 IU / 1 ml.
Njira yothetsera vutoli imapezeka m'mabotolo kapena makatoni, ogulitsa ndi ma processor a Solostar.
Zotsatira za pharmacological
Ma insulin omwe amapezeka mu mankhwalawa amapangidwa pogwiritsa ntchito biotechnologies pantchito yopanga majini. Insulin ili ndi mawonekedwe ofanana ndi anthu.
Mphamvu ya pharmacological ikuwonetsedwa ndi kuchepa kwa glucose. Pali kuchepa kwa njira zowonongeka, kuthamanga kwa zotsatira za anabolic. Mankhwala amalimbikitsa kusamutsa glucose kumalo achilengedwe, kuchuluka kwa zovuta za glycogen mu minofu ya minofu ndi chiwindi. Kutulutsa kwa pyruvic acid kuchokera mthupi kumakhala bwino. Potengera maziko awa, kupanga glucose kuchokera ku glycogen, komanso kuchokera ku mamolekyulu a mankhwala ena okhala ndi michere, amachepetsa.
Makina ochitapo kanthu amadziwika ndi kuwonjezeka kwa kagayidwe ka glucose mpaka mafuta acids ndi kuchepa kwa kuchuluka kwa lipolysis.
Kugawidwa kwa amino acid ndi potaziyamu m'maselo, metabolism ya protein imayenda bwino.
Pharmacokinetics
Ndi subcutaneous makonzedwe, kuyambitsa kwa izi kumawonedwa mkati mwa theka la ola. Kuchuluka kwake kumatenga maola 1 mpaka 4. Kutalika kwathunthu kwa mankhwalawa kumachokera maola 7 mpaka 9.
Kutalika kapena kufupikitsa
Chochita chogwira chimadziwika ndi nthawi yayifupi yofunikira.
Insuman Rapid GT ndi mankhwala a hypoglycemic omwe amapatsidwa shuga.
Zizindikiro zogwiritsidwa ntchito
Kulembera Milandu:
- mankhwala a insulin;
- kupezeka kwa zovuta za matenda ashuga.
Amagwiritsidwa ntchito tsiku lisanafike komanso munthawi ya opaleshoni, pakukonzanso nthawi kuti athandizire kubwezeretsedwa kwa metabolic.
Contraindication
Contraindication ku mankhwala ndi hypoglycemia ndi tsankho la yankho.
Kugwiritsa ntchito mosamala kumafunika pa milandu monga:
- Kulephera kwamkati ndi chiwindi.
- Kugwedeza kwamitsempha yaubongo ndi myocardium.
- Zaka zopitilira 65.
- Proliferative retinopathy.
Ndi matenda ophatikizika mwangozi, kufunikira kwa insulin kumatha kuchuluka, kotero kugwiritsa ntchito mankhwalawa kumafunikiranso kusamala.
Momwe mungatengere Insuman Rapid GT
Njira yothetsera vutoli ndi yothandiza kuti ma intravenous komanso subcutaneous ayende. Palibe mankhwala amodzi omwe amaperekedwa ndi mankhwalawa. Njira zochizira zimafunikira kusintha kwa dokotala. Odwala osiyanasiyana amakhala ndi magawo osiyanasiyana a glucose omwe amafunikira kuti azisamalira, motero, kuchuluka kwa mankhwalawo ndi njira zochizira zowerengedwa zimawerengedwa payekhapayekha. Dokotala yemwe amapezekapo amaganizira zochita za wodwalayo.
Kufunika kusintha kuchuluka kwa mankhwalawa kumatha kuchitika:
- Mukamasintha mankhwalawo ndi mtundu wina wa insulin.
- Ndi kukhudzika kowonjezereka kwa chinthucho chifukwa chakuyenda bwino kwa kagayidwe kazinthu.
- Mukataya kapena kulemera ndi wodwala.
- Mukamakonza zakudya, kusintha kuchuluka kwa katundu.
Njira yolowera pakayendetsedwe ka chipatala imachitika zofunikira pakuwunika momwe wodwalayo alili.
Makina oyendetsera zinthu ndi ozama. Ndi bwino kuchita njirayi kwa mphindi 15 kapena 20 musanadye. Ndikofunikira kuti musinthe jekeseni ndi jekeseni aliyense. Komabe, kutengera gawo la kayendetsedwe ka yankho, ma pharmacokinetics a mankhwalawa amatha kusintha, kotero kusintha kwa malo oyang'anira kuyenera kuvomerezedwa ndi adokotala.
Ndikofunika kulabadira kupezeka kwa chipewa. Izi zikuwonetsa kukhulupirika kwa nkhanizo. Palibe zidutswa zomwe zimayenera kukhalapo mu yankho, madziwo ayenera kukhala owonekera.
Zotsatirazi ziyenera kuganiziridwa:
- Mukamagwiritsa ntchito njirayi mosamala, gwiritsani ntchito syringe yoyenera yapulasitiki.
- Choyamba, mpweya umasonkhanitsidwa mu syringe, kuchuluka kwake kuli kofanana ndi mlingo wa yankho. Lowetsani malo opanda kanthu m'botolo. Mphamvu zimatembenuka. Yothetsera ikuchitika. Pasapezeke thovu mumlengalenga. Pang'onopang'ono Lowani yankho mu khola la khungu lopangidwa ndi zala.
- Pa zilembo muyenera kufotokoza tsiku lomwe mankhwala oyamba adachitika.
- Mukamagwiritsa ntchito makatoniji, kugwiritsa ntchito ma jakisoni (zolembera) pamafunika.
- Katoniyo amalimbikitsidwa kuti asiyidwe firiji kwa 1 kapena 2 maola, monga kuyambitsidwa kwazinthu zopweteka kumakhala kowawa. Pamaso jakisoni, chotsani mpweya wotsalira.
- Katiriji sikulembedwanso.
- Ndi cholembera chosagwira ntchito, syringe yoyenera imaloledwa.
Njira yolowera pakayendetsedwe ka chipatala imachitika zofunikira pakuwunika momwe wodwalayo alili.
Kukhalapo kwa zotsalira za mankhwala ena mu syringe ndikosavomerezeka.
Zotsatira zoyipa Insuman Rapid GT
Zotsatira zoyipa ndizotsika kwambiri m'ndondomeko ya shuga. Nthawi zambiri, izi zimachitika pamene mlingo wa insulin sutsatiridwa. Zolemba mobwerezabwereza zimayambitsa kusokonezeka kwa mitsempha. Mitundu yambiri yamavuto, limodzi ndi kukhudzika, kusayenda bwino kwa kayendedwe ndi kukomoka, ndi owopsa pamoyo wa wodwalayo. Muzochitika izi, kugonekedwa kuchipatala ndikofunikira.
Moyang'aniridwa ndi ogwira ntchito zachipatala, Zizindikiro zimayimitsidwa ndikugwiritsa ntchito njira yokhazikika ya dextrose kapena glucagon. Zizindikiro zofunika za kagayidwe kazinthu, kuchuluka kwa electrolyte ndi kuchuluka kwa asidi-acid zimasonkhanitsidwa. Mlingo wa hemoglobin wa glycosylated umayang'aniridwa.
Phenomena yochokera pakuchepa kwa shuga mu ubongo ingatengedwere ndikuwonetsedwa kwa chiwonetsero chazomwe zimayendetsa gawo la mtima wamanjenje. Kutsika kwakukulu kwa shuga m'magazi kungakhudze kuchuluka kwa potaziyamu, kuchititsa hypokalemia ndi edema yamatumbo.
Kuthamanga kwa magazi kumatha kuchepa.
Pa mbali ya ziwalo zamasomphenya
Kusinthasintha komwe kumanenedwa pakuwongolera glycemic kumatha kubweretsa kusokonezeka kwakanthawi kwa cell membrane wamaso a mandala amaso, kusintha kwa cholowezera. Kusintha kwakuthwa kwa zizindikiro chifukwa cha kuchuluka kwa mankhwala kungakhale limodzi ndi kuwonongeka kwakanthawi mkhalidwe wa retinopathy.
Mu kwambiri hypoglycemia yokhala ndi retinopathy yowonjezereka, kuwonongeka kwa retina kapena kuwala kwa minyewa yochepa kwakanthawi kumatha.
Hematopoietic ziwalo
Nthawi zina munthawi yamankhwala, ma antibodies a m'thupi amatha kupangidwa. Pankhaniyi, kusintha kwa muyezo ndikofunikira.
Pa khungu
Patsamba la jakisoni, kukulira kwa ma pathologies a adipose minofu, kuchepa kwa mayankho am'deralo kwa chinthucho, ndizotheka.
Kuluma, kupweteka, kufiyira, ming'oma, kutupa, kapena kutupa kumawonekera m'malo a jekeseni.
Kuchokera kumbali ya kagayidwe
Kusokonezeka kwakutheka kwa metabolism ya sodium, kuchepa kwake m'thupi ndi mawonekedwe a edema.
Matupi omaliza
Kutulutsa khungu, bronchospasm, angioedema, kapena anaphylactic mantha ndizotheka.
Zokhudza mphamvu pakuwongolera njira
Mavuto azachipatala angayambitse kusokonezeka kwa chidwi, kuchepa kwa zomwe zimachitika. Izi zitha kukhala zowopsa poyendetsa makina ndi magalimoto.
Malangizo apadera
Sangagwiritsidwe ntchito pamapampu okhala ndi silicone tubing.
Gwiritsani ntchito mu ukalamba
Odwala atatha zaka 65, ntchito ya impso imachepa. Izi zimaphatikizapo kuchepa kwa kuchuluka kwa insulin.
Kupatsa ana
Pochiza ana, kusankha mosamala mlingo kumachitika, chifukwa kufunika kwa insulini ndikotsika kuposa akuluakulu. Pofuna kupewa kukula kwa hyperglycemia, glucose imayang'aniridwa.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yobereka komanso pambuyo pobereka, chithandizo sichimayima. Kuwongolera kwa regimen ya chithandizo ndi kumwa kungafunike chifukwa cha kusintha kwa insulin.
The ntchito aimpso kuwonongeka
Zotsatira zake pakuchepetsa kwa kagayidwe kachakudya ndi insulin mthupi, kufunikira kwa chinthuchi kumachepa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Kutha kupanga glucose pamagulu omwe alibe mafuta kumachepetsa. Izi zitha kuchepetsa kufunika kwa chinthu.
Overdose wa Insuman Rapid GT
Kupanga kwambiri thupi kufunika kwa insulin Mlingo kumabweretsa kukula kwa hypoglycemia.
Kuchita ndi mankhwala ena
Kumwa mankhwala munthawi ya insulin chithandizo kuyenera kugwirizanitsidwa ndi dokotala.
Kumwa mankhwala munthawi ya insulin chithandizo kuyenera kugwirizanitsidwa ndi dokotala.
Kuphatikiza kophatikizidwa
Kuphatikiza kwa mankhwalawo ndi insulin ya nyama ndi analogues sikuyikidwa pambali.
Kuphatikiza kwa Pentamidine kumapangitsa kuti pakhale zovuta.
Osavomerezeka kuphatikiza
Zinthu zotsatirazi ndi kukonzekera kumafooketsa mphamvu yotsitsa shuga:
- corticosteroids;
- adrenocorticotropic timadzi;
- zotumphukira za phenothiazine ndi phenytoin;
- glucagon;
- mahomoni ogonana achikazi;
- kukula kwamafuta;
- nicotinic acid;
- phenolphthalein;
- okodzetsa
- mankhwala osokoneza bongo;
- kupanga androgen Danazole;
- anti-TB mankhwala Isoniazid;
- adrenoblocker Doxazosin.
Sympathomimetics ndi iodinated tyrosine zotumphukira zimafooketsa mayankho a yankho.
Kuchepetsa mphamvu yochepetsera shuga ya anti-TB mankhwala a Isoniazid.
Kuphatikiza komwe kumafunikira kusamala
Mankhwala otsatirawa amalimbikitsa chiopsezo cha zovuta:
- endrogens ndi anabolics;
- angapo mankhwala zochizira mtima ndi minyewa;
- CNS zolimbikitsa;
- antiarrhythmic mankhwala cybenzoline;
- propoxyphene analgesic;
- pentoxifylline angioprotector;
- cytostatic mankhwala trophosphamide;
- angapo antidepressants;
- sulfonamides;
- mankhwala angapo omwe cholinga chake ndi kuchepetsa cholesterol;
- tetracycline mankhwala;
- kukonzekera kutengera somatostatin ndi mawonekedwe ake;
- othandizira a hypoglycemic;
- chilangizo chowongolera fenfluramine;
- antitumor mankhwala ifosfamide.
Kusamala kumafuna kumwa mankhwala potengera msuzi wa salicylic acid, tritokvalin, cyclophosphamide, guanethidine ndi phentolamine.
Mchere wa Lithium ukhoza kusintha kapena kuwonjezera mphamvu ya mankhwalawo. Reserpine ndi clonidine amasiyana mu zomwezo.
Kugwiritsa ntchito ma beta-blockers kumawonjezera chiopsezo cha zovuta.
Kuyenderana ndi mowa
Pazakumwa zoledzeretsa, kuchuluka kwa glycemia kumasintha. Ndi matenda ashuga, kulolera mowa kumachepa, ndipo kufunsira kwa dokotala ndikofunikira kuti pakhale mankhwala osokoneza bongo otetezeka. Kuchulukitsa kwa glucose kumatha kutsika kwambiri.
Analogi
Insulin yaumunthu imakhala ndi mankhwala monga Insuran, Actrapid, Humulin, Rosinsulin, Biosulin, etc.
Kupita kwina mankhwala
Sichili mndandanda wamankhwala omwe ali pamsika waulere.
Kodi ndingagule popanda kulandira mankhwala?
Amamasulidwa pa chiwonetsero cha Chinsinsi.
Mtengo wa Insuman Rapid GT
Mtengo wapakatikati wa ma CD ndi ma ruble a 1000-1700.
Zosungidwa zamankhwala
Ulamuliro wazotentha posungira mankhwalawa ndi + 2 ... + 8 ° C. Osatsamira chidebe kumbali ya makoma a firiji kuti isasungunuke yankho.
Mukatha kugwiritsa ntchito koyamba, botolo limatha kusungidwa kwa maola 4, cartridge - kwa masiku 28 mutatha kuyika. Pakusunga, kuyatsa kuwala kuyenera kupewedwa ndipo kutentha sikuyenera kuloledwa kukwera pamwamba + 25 ° C.
Tsiku lotha ntchito
Kuyambira tsiku lopangira, yankho ndi loyenera kugwiritsidwa ntchito kwa zaka ziwiri.
Wopanga
Mankhwalawa amapangidwa ndi Sanofi-Aventis. Dziko lopanga limatha kukhala Germany kapena Russia.
Ndemanga za Insuman Rapid GT
Vasily Antonovich, endocrinologist, Moscow: "Kugwiritsa ntchito jakisoni kwambiri ndi yankho kunadziwika. Mankhwalawo ali ndi chitetezo chokwanira komanso kulekerera kwabwino."
Daria, wazaka 34, Severodvinsk: "Mankhwala ena adathandizanso kuposa Rapid. Chifukwa cha jakisoni, ndimatha kukhazikika pamlingo wa shuga. Nthawi zonse ndimayang'ana mafuta ndi glucometer ndikumayendetsa mankhwalawa musanadye."
Marina, wazaka 42, Samara: "Mukamawagwiritsa ntchito ana, ndikofunikira kufunsa dokotala kuti adziwe za kuchuluka kwa mankhwala osokoneza bongo, kuwunika kuchuluka kwa zomwe zikuwonetsa. Monga chithandizo cha insulin, mankhwalawa amaperekedwa kwa mwana wamwamuna, mankhwala abwino."
