Malangizo a formethine ogwiritsira ntchito amadziwika kuti ndi mankhwala othandizira odwala omwe ali ndi vuto la Biguanide. Chilendo cha mankhwalawa ndizogwiritsidwa ntchito mosiyanasiyana: mapiritsi angagwiritsidwe ntchito pochiza matenda amishuga a 2, tengani Foromu ndi omwe mtundu wawo wanenepa kwambiri samakulolani kuti muchepetse thupi kokha kudzera mu zakudya komanso masewera.
Ambiri odwala matenda ashuga amaloleza chithandizo mosavuta, zotsatira zosafunikira zimachitika mosavuta ngati malangizo ndi malamulo operekedwa ndi adotolo sanatsatidwe. Mtundu wa malangizo omwe ali patsamba lino amasinthidwa, amathandizidwa ndi owunika ndi ndemanga. Ndikosatheka kuzimva ngati chitsogozo chodzidzipangira nokha.
Mlingo wa Mlingo ndi malo osungira
Kunja, mankhwalawa amawoneka ngati piritsi loyera loyimbira loyera lokhala ndi mzere wogawika popanda kukoma kapena kununkhira kwapadera. Mapiritsiwo amakhala ndi matuza, mu bokosi pamakhala zidutswa 10 kapena 12 za mitundu yosiyanasiyana: 0,5 g, 0,85 g kapena 1 g iliyonse. Amapangidwa kuti azigwiritsa ntchito pakamwa.
Paketi imodzi imatha kuwerengera kuchokera pamapiritsi 30 mpaka 120. Forformin, mtengo umatengera kuchuluka kwa mapiritsi omwe ali m'bokosi komanso m'deralo. Mtengo waukulu wa mankhwala ogwirira ntchito zapakhomo ndi ruble 250. (Fomu 1000, mtengo wa mapiritsi 60).
Mankhwalawa safuna mikhalidwe yapadera kuti asungidwe. Pamtunda wofunda (+ 25 ° C) kutali ndi kuwala kowala ndi chidwi cha ana, Fomu likhoza kusungidwa kwa zaka 2 - moyo wa alumali ukusonyezedwa phukusi. M'tsogolomu, mankhwalawa ayenera kutayidwa.
Limagwirira a zochita za formin
Gawo loyambirira la mankhwala ndi metformin hydrochloride. Kuphatikiza pa ntchito yogwira, palinso ma exipi omwe amapangidwa: magnesium stearate, croscarmellose sodium, povidone.
Mphamvu za Formetin, zomwe chithunzi chake chitha kuwonekera m'gawoli, ndizachilengedwe:
- Lowers glycemia;
- Kuchulukitsa chidwi cha maselo ku insulin;
- Imalepheretsa mayamwidwe a shuga;
- Ilamulira kagayidwe ka lipid:
- Sichimupangitse kulemera.
Mankhwala samathandizira kupanga ma ambulensi amkati, ma the-cell a kapamba, omwe amachititsa kuti apangidwe, asadzaza. Metformin imatengedwa mwachangu: nsonga ya kuchuluka kwake imawonedwa patatha maola awiri.
Ubwino wina wa metformin ndi kuyanjana kochepa ndi mapuloteni amwazi. Formetin siyabwino pakukula kwa hypoglycemia. Gawo lolimbikira limadziunjikira mu minofu, impso, chiwindi, tiziwalo timene timagwira. Imapukutidwa makamaka ndi impso. Kuwunika kwa metformin kumatheka pokhapokha ndikuwonetsa matenda a impso. Pambuyo pa ola limodzi ndi theka, kumasulidwa kwa chinthu chogwira ntchito ndi mkodzo kumayamba.
Popeza mankhwalawa ali ndi katundu wowonjezera pamtundu wa genitourinary, mawonekedwe a impso ndi matenda ashuga amayenera kuwunikiridwa kawiri pachaka.
Momwe mungamwere mapiritsi
Mlingo wa tsiku ndi tsiku wa mankhwalawo nthawi zambiri amagawika pawiri. Malangizo olondola amakonzedwa ndi adokotala. Chithandizo chimayamba ndi Mlingo wochepa (0.5-0.85 g / tsiku), kamodzi pa sabata endocrinologist amatha kusintha mlingo kutengera zotsatira za kuyezetsa magazi. Mulingo woyenera ndi 3 ma PC / tsiku.
Metformin nthawi zambiri imatengedwa mphindi 20 asanadye. Kenako magawo azakudya ndi mankhwala amanjana.
Kudumpha zakudya mukatha kumwa mankhwalawa ndizowopsa: mutha kuyambitsa shuga.
Forimetin imatengedwa momasuka ndi odwala matenda ashuga omwe amayendetsa kayendedwe kazinthu zovuta, chifukwa sizimayambitsa zotsatira zosasangalatsa zomwe zimachepetsa chidwi komanso kuthamanga kwa zomwe zimachitika.
Ndani amalimbikitsidwa komanso pamene mankhwalawa apangika
Formetin adapangidwa kuti azilamulira matenda ashuga amtundu wa 2. Imakhala ndi jakisoni wa insulin pophatikiza mankhwalawa, angagwiritsidwe ntchito ngati mankhwala osinthika ngati zakudya zosinthika (zakudya zama carb ochepa, zochitika zolimbitsa thupi zokwanira) sizipereka zotsatira zomwe zikuyembekezeka.
Poyerekeza ndi ndemanga, formatein yochepetsa thupi imasonyezedwa mtundu wa kunenepa kwambiri wokhudzana ndi matenda ashuga omwe ali ndi mtundu wachiwiri wa matendawa, pomwe ma deposits amafuta amapezeka pazilonda zam'mimba, makamaka pamimba.
Kugwiritsa ntchito mankhwala akulu kukonza mawonekedwe a munthu wathanzi ndizowopsa.
Osagwiritsa ntchito mankhwalawa:
- Ndi hypersensitivity ku zosakaniza za formula;
- Ngati chiopsezo cha lactic acidosis ndichokwera kwambiri;
- Ndi mavuto owopsa a chiwindi;
- Pankhani ya uchidakwa kwambiri ndi mbiri yakumwa mowa;
- Ngati pali matenda enanso opatsirana;
- Ngati wodwala matenda ashuga ali pakudya yanjala (mpaka 1000 kcal / tsiku);
- Ndi ketoacidosis;
- Aakulu ndi pachimake aimpso matenda;
- Ngati wozunzidwayo ali ndi vuto kapena asanakumanepo nalo;
- Pakakhala mbiri yamilandu yamtima, kuphwanya kwamitsempha yamagazi.
Ndi kupsa kwambiri, kuvulala kwambiri, musanayambe kuchita opaleshoni, wodwalayo amaperekanso insulin. Ngati chikhazikitso cha ayodini chikuperekedwa kwa wodwala matenda ashuga, masiku awiri asanafike komanso masiku atatu atatha kuyesedwa, Formmetin imathetsedwa.
Pokhala ndi zolephera, amagwiritsa ntchito Forthine wa anthu opitilira 65, chifukwa impso ndi ziwalo zina za anthu odwala matenda ashuga okalamba sizabwino kwambiri, ndipo chiopsezo chokhala ndi lactic acidosis chikuwonjezeka.
Zotsatira zoyipa ndi bongo
Poyerekeza ndi ndemanga pamisonkhano yamtundu, formimetin odwala matenda ashuga amalolera bwino. Komabe, malangizowa ali ndi ziwonetsero zingapo za zomwe zingachitike ngati munthu ali ndi mankhwala osokoneza bongo kapena munthu payekha.
- Matumbo. Nthawi zina (mu 3% ya milandu) kusokonezeka kwa dyspeptic, kuphwanya mtundu wa defecation, kusowa chilakolako cha chakudya, ndi kupweteka kwa epigastrium amalembedwa.
- Ziwengo Kuchita zimawonekera mu mawonekedwe a totupa (manja, chifuwa, masaya), kuyabwa ndi kuwonekera kwa khungu. Nthawi zina, kutentha thupi kumatha.
- Dongosolo la Endocrine. Hypoglycemia imachitika pakakhala zovuta zina zamagulu ena omwe amalimbitsa mphamvu za metformin, ndikusintha kwamomwe mulingo wapamwamba ndi Mlingo wa formin.
- Kupenda. Mwazowopsa, lactic acidosis imawonedwa - mkhalidwe wowopsa womwe umafuna kusiya mwachangu mankhwala ndi chithandizo chapadera.
- Pogwiritsa ntchito metformin kwanthawi yayitali, mayamwidwe ake amachepa, izi zimakhudzanso mavitamini B12 (bongo wambiri ndiwotheka).
- Njira yozungulira. Pali zigawo (zosowa) za kuchepa kwa magazi m'thupi.
Malinga ndi ziwerengero, zotsatira zoyipa zimawonetsedwa nthawi yoyamba mankhwalawa, mpaka thupi litasintha. Ndi kugwiritsa ntchito pafupipafupi mwezi umodzi, zizindikiro zambiri zimazimiririka popanda kukonza njira yochizira. Ndi zovuta zoyipa, adokotala amatha kukupatsani mankhwala antispasmodic kapena antacid.
Ngati mwangozi kapena mwamukulitsa mlingoyo kangapo, zotsatirapo zake zingakhale zovutirapo (mpaka kufa). Lactic acidosis imathanso kuchitika ngati mulingo wawonetsedwa, ngati impso zakana kupukusa metabolites munthawi.
Zizindikiro zoyambirira za lactic acidosis:
- Dontho lakuthwa mu kuthamanga kwa magazi;
- Myalgia;
- Thupi kapena kuzizira;
- Kuyenda kwamtima pang'ono
- Kugwirizana kwamisala;
- Kupuma pang'ono
- Matenda a shuga.
Ngati pali zingapo mwa zomwe zalembedwa, kugwiritsa ntchito mankhwalawa kuyimitsidwa, wogwidwayo amapatsidwa zotengera kuti atulutse m'mimba kuchokera kumatsalira osagwiritsidwa ntchito ndi mankhwala, ndipo apempha thandizo kuchipatala. Panthawi yachipatala, hemodialysis imachitidwa, chothandizira cha mankhwala chimayikidwa.
Zotsatira Zogwiritsa Ntchito Mankhwala
Formmetin ndi mankhwala apadziko lonse: angagwiritsidwe ntchito monotherapy kapena kuphatikizidwa ndi mankhwala ena a hypoglycemic, kuphatikiza jakisoni wa insulin.
Koma nthawi zina, pochiza matenda ophatikizika, kuchira kwovuta kumatha kukhala ndi zotsatirapo zoyipa.
- Ndi makonzedwe omwewo a Danazol, pali chiopsezo cha zotsatira za hypoglycemic, kotero mlingo wa mankhwalawo uyenera kuyendetsedwa mosamalitsa ndi analog.
- Akaphatikizidwa ndi cimetidine, mawonekedwe a metformin amalephereka, kuchuluka kwake mthupi kumatha kupereka mphamvu yosagwirizana ndi hypoglycemic.
- Kuthekera kwa zotumphukira za coumarin ndizolepheretsa ndi metformin.
- Mankhwala osakanikirana ndi carbazole, NSAIDs, clofibrate, insulin, ACE inhibitors, cytophosphamide, β-blockers, sulfonylureas, oxytetracycline amathandizira ntchito ya metformin.
- Kuphatikiza komweko kwa glucagon, epinephrine, thiazide diuretics, mahomoni a chithokomiro amalepheretsa kugwira ntchito kwa formin.
Pogwiritsa ntchito njira zakulera zamkamwa, mayi ayenera kuuza mitundu ya mankhwalawo kwa endocrinologist kuti asinthe mlingo wa Formetin. Osam'patsa mankhwala komanso kuphatikiza ndi Nifedipine, womwe umakulitsa kuchuluka kwa metformin m'magazi, imathandizira kuyamwa kwake, imachepetsa kuchoka. Ngati pali vuto ndi impso, zotsatira zake zingayambitse kukomoka.
Ngati mankhwalawa apangidwa pamaziko a ethanol, kuphatikiza ndi metformin, chiopsezo cha lactic acidosis chimawonjezeka kwambiri.
Formetin - analogues
Gululi (mankhwala antidiabetesic mankhwala) komanso othandizira (metformin hydrochloride), mankhwalawa akutsatira: Metamine, Bagomet, NovoFormin, Fomu.
Malinga ndi mphamvu ya mankhwala a Formetin ndi ofanana:
- Lymphomyozot;
- Multisorb;
- Glidiab;
- Januvius;
- Baeta;
- Glucobay;
- Glemaz;
- Apidra
- Glurenorm;
- Piroglar;
- Levemir Flekspen;
- Levemir Penfill;
- Avandia
Kusankha kwina komwe kumachepetsa mankhwala ochepetsa shuga mumsika wamankhwala ndikofunikira, ngakhale katswiri ndizovuta kuyendera pamodzinso. Ndipo, odwala matenda ashuga kuyesa kwambiri thanzi lawo. Chifukwa chake, simuyenera kudalira malingaliro a oyandikana nawo kapena otsatsa pankhaniyi. Dokotala yekha ndi amene angasankhe bwino m'malo mwake, poganizira kuopsa kwa matendawa komanso thanzi lanu lonse.
Malingaliro a odwala matenda ashuga pa Formetin
About Fomu, ndemanga za anthu odwala matenda ashuga amasakanikirana. Iwo omwe amamwa mankhwalawo kwa nthawi yayitali, amadziwa zabwino zake. Oyamba kumene amadandaula za mavuto. Matenda a Dyspeptic amatha okha patapita milungu ingapo, ngati simukuyesa kuonana ndi dokotala. Ngakhale zoletsa za zaka zomwe zikuwonetsedwa mu malangizo ziyenera kukumbukiridwa.
Metformin yochokera kuformformin ndi mankhwala apakhomo okhala ndi umboni waukulu. Nthawi zambiri, makamaka ndi matenda a shuga a 2, palibenso njira ina yodziwira mankhwala a metformin. Chifukwa chake, musathamangire kuti mumvetsetse za kuyenera kwake, ndibwino kuti muthandize thupi kuti lizolowera mankhwala ena mothandizidwa ndi chakudya, malingaliro oyenera azamankhwala komanso magawo olimbitsa thupi oyenera. Popanda njira iyi, mankhwala omwe angokhala kumene sangakhale opanda ntchito.
