Chimodzi mwazodziwika bwino za mankhwala osagwiritsa ntchito mankhwalawa omwe amaletsa mankhwala osokoneza bongo ndi mapiritsi a acetylsalicylic acid. Chogulitsachi chili ndi antipyretic ndi antiplatelet kwenikweni (chimalepheretsa kuphatikiza kupatsidwa zinthu za m'magazi, kupewa thrombosis).
Mankhwalawa agwiritsidwa ntchito kwa nthawi yayitali ngati mankhwala, ophunziridwa bwino ndikuzindikiridwa ngati mankhwala ofunikira. Unali ndi mwayi ndipo unalowa mumsika womwe umatchedwa Aspirin kuchokera ku kampani yopanga mankhwala ku Germany Bayer.
Aspirin amapezeka muzinthu zazitsamba: maapulo, ma jamu, currants, yamatcheri, rasipiberi, cranberries, mphesa, tsabola wokoma ndi ena ambiri.
Dzinalo Losayenerana
Acetylsalicylic acid (ASA) onse ndi dzina wamba komanso lamalonda. Mu Latin - Acidum acetylsalicylicum.
Acetylsalicylic acid imakhala ndi antipyretic ndi antiplatelet.
ATX
Nambala za ATX ndi B01AC06, A01AD05, N02BA01.
Kutulutsa mafomu ndi kapangidwe kake
Kutulutsa mawonekedwe - mapiritsi. Amatha kukhala mu chipolopolo, popanda chipolopolo, polingirira enteric, efflementscent, khanda. Atadzaza matuza ndi makatoni.
Zomwe zimagwiritsa ntchito mankhwalawa ndi Acidum acetylsalicylicum.
Mapiritsiwo ndi oyera, osalala, osindikizidwa bwino, okhala ndi chamfer chofuna kumeza mosavuta komanso ali ndi chiopsezo mbali imodzi.
Mapiritsi amatha kukhala mu chipolopolo, chopanda chipolopolo, chophimba cha enteric, chowongolera, cha ana.
Njira yamachitidwe
Aspirin amalepheretsa kaphatikizidwe ka thromboxane A2, amachepetsa kumamatira kwa mapulateleti ndi kuthekera kwawo pakupanga magazi. Izi zimapitilira kamodzi kwa sabata limodzi.
Pharmacokinetics
Mankhwalawa ali ndi bioavailability wambiri: chinthu chogwira ntchito chimakhala chokwanira. Kuchotsa theka moyo ndi pafupifupi mphindi 20. Kuzindikira kwambiri m'magazi kumachitika patatha maola awiri. Imalowa m'matumbo, kudutsa mkaka wa m'mawere. Ma salicylates amapezeka m'madzi amadzimadzi (cerebrospinal, synovial, peritoneal), ochepa - mu minofu yaubongo, mawonekedwe amapezeka mu ndulu, ndowe, thukuta.
ASA metabolism imachitika m'chiwindi, komwe ma metabolites anayi amapangidwa ndi hydrolysis. Imafufutidwa kudzera mu impso zosasinthika (60%) komanso mawonekedwe a metabolites (40%).
Mankhwalawa amachotseredwa kudzera mu impso zosasinthika (60%) komanso mu mawonekedwe a metabolites (40%).
Zomwe zimathandiza
ASA imathandizira ndi mitundu yosiyanasiyana ya ululu: kupweteka mutu, kuphatikizira, kupweteka mano, minofu, kusamba. Mankhwalawa amagwiritsidwa ntchito pochiza matenda, matenda a kutupa, mikwingwirima, matenda amtima, kuletsa kukula kwa matenda achilengedwe, munthawi yomwe akutsatiridwa kuti mupewe mapangidwe a magazi.
Zowonetsa:
- Ischemia wamtima.
- Angina pectoris.
- Kukhalapo kwa zinthu zoopsa za matenda a mtima.
- Rheumatoid nyamakazi
- Arrhythmias.
- Zofooka za mtima.
- Myocardial infaration.
- Ischemic stroke.
- Prosthetics yamavala amtima.
- Mitral valve prolfall.
- Matenda a Kawasaki.
- Arteritis Takayasu.
- Pericarditis.
- Tela.
- Pulmonary infaration.
- Thrombophlebitis wa mawonekedwe pachimake.
- Systemic sclerosis ya pang'onopang'ono maphunziro.
- Thupi mu matenda opatsirana.
- Lumbago.
- Neuralgia
- Mutu wopsinjika ndi intracranial.
Contraindication
- Kuzindikira kwakukulu pazinthu zogwira ntchito kapena zowonjezera zina za mankhwala.
- Kuchulukana kwa zilonda zam'mimba zam'mimba.
- Zambiri matenda a impso ndi chiwindi.
- Hemorrhagic diathesis: telangiectasia, magazi ochulukirapo.
- Kulephera kwa mtima.
- Mphumu ya bronchial yomwe imayambitsidwa ndi NSAIDs ndi salicylates.
- Hyperuricemia
- Vitamini K akusowa
- Hypoprothrombinemia.
- Kutulutsa msempha.
- Supombocytopenic purpura.
- Supombocytopenia.
- Zoberekera za fetal (woyamba ndi wachitatu wozungulira).
- Kuchepetsa mkaka (kuyamwitsa kuyenera kuyimitsidwa kwa nthawi ya mankhwala ndi aspirin).
- Kumwa methotrexate muyezo wa 15 mg pa sabata.
- Ana osakwana zaka 6.
- Ana osakwana zaka 15 zochizira matenda apakhungu opatsirana ndi ma virus.
Contraindations zimaphatikizapo kubereka mwana wosabadwayo.
Ndi chisamaliro
Chenjezo liyenera kugwiritsidwa ntchito mu nyengo yachiwiri ya mimba, mukamamwa ndi anticoagulants ndi methotrexate komanso pamaso pa matenda otsatirawa:
- zilonda zam'mimba;
- gout
- aimpso ndi chiwindi kulephera;
- zigawo za magazi m'mimba;
- chifuwa;
- mphumu
- ma polyp a mphuno;
- hay fever;
- COPD
- kusowa kwa shuga-6-phosphate dehydrogenase.
Momwe mungatenge asidi acetylsalicylic
Mapiritsi a ASA adapangira pakamwa.
Mlingo wa akulu ndi ana zaka 12: kuchokera 500 mg mpaka 1 g pa nthawi, koma osapitilira 3 g patsiku. Mutha kumwa katatu pa tsiku, nthawi yayitali pakati pa Mlingo - osachepera maola 4.
Mankhwala amatha kuledzera katatu patsiku.
Ana kuyambira wazaka 6 mpaka 12 amaloledwa kumwa zosapiritsi 1/250 mg imodzi. Mulingo woyenera kwambiri ndi 100-150 mg. Chiwerengero cha madyerero patsiku ndi kuyambira 4 mpaka 6.
Njira ya mankhwala popanda dokotala
- ndi malungo - mpaka masiku atatu;
- kuchepetsa ululu - mpaka masiku 7.
Kumwa mankhwala a shuga
Mu matenda a shuga (makamaka mtundu 2), madokotala amalimbikitsa kumwa Aspirin mu Mlingo yaying'ono kuti muchepetse zovuta zamtima.
Zotsatira zoyipa za acetylsalicylic acid
Kuchokera pamagazi othandizira magazi
Magazi amayamba kuyenda pang'onopang'ono. Mwina chitukuko cha hemorrhagic syndrome: magazi kuchokera m`kamwa, mphuno.
Pa gawo la mapangidwe a magazi, magazi amatuluka m'mphuno.
Matumbo
Kuchokera m'matumbo, zotsatira zoyipa zimachitika:
- kupweteka kwam'mimba
- kusanza, kusanza
- kusadya bwino;
- kutentha kwa mtima;
- magazi mu masanzi, ndowe zakuda;
- magazi m'mimba;
- kutsegula m'mimba
- kuwonongeka kwa chiwindi;
- zilonda zam'mimba.
Hematopoietic ziwalo
Pali chiopsezo cha thrombocytopenia, leukopenia, kuchepa magazi.
Pakati mantha dongosolo
Pogwiritsa ntchito nthawi yayitali, mutu umawoneka, kuwonongeka ndikuwonera kumawonedwa, meningitis imayamba. Ngati bongo, tinnitus ndi chizungulire zimachitika.
Kuchokera kwamikodzo
Ntchito yeniyeni ikuipa, kuchuluka kwa magazi aininine kumakwera, hypercalcemia, nephrotic syndrome, kulephera kwa impso, kukulira edema.
Matupi omaliza
Pali zotupa pakhungu ndi kuyabwa, pali chiopsezo chotenga bronchospasm, edema ya edi ya Quincke ndi kugwedezeka kwa anaphylactic.
Zokhudza mphamvu pakuwongolera njira
Amakhulupirira kuti ASA sichikhudza kuthekera koyendetsa magalimoto ndi zinthu zina zomwe zimafunikira kwambiri.
Amakhulupirira kuti ASK sikukhudza kuyendetsa magalimoto ndi zina.
Malangizo apadera
ASA imalimbikitsa magazi. Izi zikuyenera kukumbukiridwa pokonzekera njira zochitira opaleshoni, kuphatikizapo kuphipha mano, komanso kuchenjeza opereshoni. Ndikulimbikitsidwa kuti musiye kumwa mankhwalawo sabata imodzi musanachite opareshoni kuti muchepetse magazi munthawi ya opareshoni.
Gwiritsani ntchito mu ukalamba
Madokotala amalimbikitsa kutenga Aspirin mu Mlingo wung'ono woyang'aniridwa ndi dokotala kwa anthu opitilira 60 kuti ateteze matenda amtima: kukhumudwa, kugunda kwa mtima, magazi.
Kupatsa ana
Ana sanalembedwe Aspirin chifukwa cha mapapo omwe amayamba chifukwa cha kupuma kwamankhwala, chifukwa cha ngozi yokhala ndi matenda a Reye, omwe amadziwika ndi kuchepa kwa mafuta a chiwindi, encephalopathy, komanso kulephera pachimake kwa chiwindi.
Ana samayikidwa Aspirin chifukwa cha nthenga chifukwa chokhala ndi vuto la Reye.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Mu trimester yoyamba, kutenga ASA kumatha kubweretsa kukula kwa fetus mu fetus, mu nthawi yachitatu imatha kuchepa kwa ntchito, kumayambitsa pulmonary vascular hyperplasia, komanso kutsekedwa msanga kwa ductus arteriosus mwana wosabadwayo.
Aspirin amadutsa mkaka wa m'mawere ndikulimbikitsa kukula kwa magazi mu mwana.
The ntchito aimpso kuwonongeka
ASA imakulitsa mayendedwe a uric acid m'thupi. Sitikulimbikitsidwa kutenga Aspirin mwa odwala omwe ali ndi uric acid m'magazi ndi mkodzo, ali ndi matenda a impso komanso akuvutika ndi gout.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Iyenera kuthandizidwa mosamala ngati vuto la chiwindi lawonongeka ndikutsutsana ndikulephera kwa chiwindi.
M'pofunika kumwa mapiritsi mosamala vuto la chiwindi.
Mankhwala ochulukirapo a acetylsalicylic acid
Mankhwala osokoneza bongo amatha kuthekera ndi muyezo umodzi wambiri kapena kumwa mankhwala ambiri ngati Aspirin. Zizindikiro za bongo wofatsa:
- kumverera kwa tinnitus;
- kufooka
- kusanza, nseru;
- kusamva kwa makutu;
- Chizungulire
- chisokonezo cha chikumbumtima;
- mutu.
Woopsa poyizoni, mawonetsedwe otsatirawa ndi otheka:
- kukokana
- malungo
- chikomokere
- kugwedeza
- dontho la shuga m'magazi;
- kulephera kwa impso ndi m'mapapo;
- tsinde;
- kusowa kwamadzi;
- pulmonary edema.
Ndi chidakwa chachikulu, ndikofunikira kuyimbira ambulansi.
Chizindikiro cha mankhwala osokoneza bongo a Aspirin chingakhale mutu.
Kuchita ndi mankhwala ena
Pogwiritsa ntchito nthawi yomweyo ndi mankhwala ena, zotsatirazi zimatheka:
- Heparin ndi anticoagulants ena - kuwonongeka kwa mucosa wam'mimba, chiopsezo chotuluka magazi.
- Methotrexate - kuchuluka kwa methotrexate.
- Ma NSAID ena ndi chiopsezo chotaya magazi am'mimba komanso kukula kwa zilonda.
- Glucocorticosteroids (kupatula hydrocortisone) - kuchepa kwa zomwe salicylates m'magazi.
- Ma narcotic painkiller, anticoagulants osadziwika, sulfonamides - zotsatira za mankhwalawa zimatheka.
- Ma diuretics, antihypertensive mankhwala - mphamvu zawo zimachepa.
- Valproic acid - kawopsedwe wake amakula.
- Othandizira a Hypoglycemic - machitidwe awo amakonzedwa.
- ACE zoletsa - antihypertensive zotsatira zimaponderezedwa.
- Paracetamol - zotsatira zoyipa zimawonjezeka ndipo katundu pa impso ndi chiwindi chimakulanso.
- Digoxin - imawonjezera kuchuluka kwa digoxin.
- Barbiturates - kuchuluka ndende ya madzi amchere a lithiamu.
- Benzromarone - uricosuria yafupika.
Kuyenderana ndi mowa
Madokotala amachenjeza kuti ASA ndi mowa sizigwirizana. Ndi munthawi yomweyo makonzedwe am'mimba, magazi am'mimba kwambiri komanso kuthamanga kwa hypersensitivity ndikotheka.
Madokotala amachenjeza kuti ASA ndi mowa sizigwirizana.
Analogi
Analogs amaperekedwa pansi pa mayina amalonda: ASK-Cardio, Aspikor, Fluspirin, Aspirin Cardio, Thrombo-ACC, Asprovit, Upsarin Upsa, Nektrim Fast, Taspir, Cardiomagnyl, etc.
Kupita kwina mankhwala
M'masitolo amasulidwa momasuka.
Kodi ndingagule popanda kulandira mankhwala?
Chithandizo chogulira Aspirin sichofunikira.
Mtengo wa acetylsalicylic acid
Mtengo wake umatengera wopanga komanso kuchuluka kwa mapiritsi omwe ali phukusili. Mtengo wapakati ndi:
- Zidutswa 10, 0,5 g - kuchokera ku ruble 5 mpaka 10;
- 20 zidutswa, 0,5 g - pafupifupi 20 ma ruble.
Mtengo wa Aspirin umatengera wopanga ndi kuchuluka kwa mapiritsi omwe ali phukusi.
Zosungidwa zamankhwala
Ndikulimbikitsidwa kuchotsa mankhwalawa kwa ana. Iyenera kusungidwa m'malo owuma pamtunda wa mpweya mpaka 20 ° C.
Tsiku lotha ntchito
Itha kugwiritsidwa ntchito zaka 4 kuyambira tsiku lomwe watulutsa.
Wopanga
ASA imapangidwa m'maiko osiyanasiyana: Germany, Switzerland, Poland, USA, ndi ena .. Ku Russia, makampani azachipatala otsatirawa akuchita nawo ntchito yopanga Aspirin:
- Uralbiopharm.
- Medisorb.
- Mankhwala.
- Mankhwala a Ozone.
- Irbit KhFZ.
- Dalchimpharm.
- Fakitoli ya Borisov.
Ku Russia, Aspirin amapangidwa ndi kampani yopanga mankhwala Medisorb.
Ndemanga pa acetylsalicylic acid
Ivan, wazaka 33, Bryansk
Ubwino waukulu wa Aspirin ndi wotsika mtengo komanso wodalirika. Mankhwalawa amagwira ntchito mosiyanasiyana, amagwira ntchito, kukoma kwake si koyipa. Ndimamwa ndi kuzizira, kupweteka mutu komanso dzino. Choyipa chake ndizotsatira zoyipa, ndikugwiritsa ntchito nthawi yayitali, muyenera kuteteza m'mimba.
Galina, wazaka 50, Omsk
Mankhwalawa ndi okalamba, kutsimikiziridwa pazaka zambiri, ndizofunika ndalama. Zimathandiza nthawi zonse ndimazizira ndi zowawa, koma timakumbukira zovuta zake, chifukwa chake timayesetsa kuti tisavulale. Makamaka muyenera kusamala ndi anthu omwe ali ndi matenda am'mimba komanso ziwalo zina zam'mimba.
Ndimagwiritsa ntchito Aspirin osati mankhwala, komanso ntchito zapakhomo. Mukayika mapiritsiwo m'mbale yamadzi, maluwa sadzachedwa. Ntchito ina ya Aspirin ndikupewa kutuluka kwa maonekedwe a chikasu kutulutsa zovala. Kuti muchite izi, muyenera kuthira mapiritsi m'madzi ndikunyowetsa malo ofunikira ndikuchuluka. Ngati mawanga ndi atsopano, ndi kovuta kupirira ndi zakale. Ndikudziwa kuti amachiyika m'miphika yamasamba akamakonzekera nyengo yachisanu, amawonjezeranso kumaso kwa ziphuphu, ndikuyigwiritsa ntchito ngati khoma.
Zhanna, wazaka 26, Moscow
Poyamba chizindikiro cha chimfine, ndimamwa mapiritsi 2 a Aspirin usiku umodzi. Nthawi zina ndimatenga kumayambiriro kwa msambo, ndipo zimachepetsa vutoli. Zimathandiza kudwala mwachangu komanso kosavuta, sizinalephereke, ndizotsika mtengo. Anamukana pa nthawi yoyembekezera komanso yoyamwitsa. Amayi amateteza kupewa matenda a mtima pamalangizo a dokotala. Ndikudziwa kuti amalembera kuwonda kwamitsempha, yokhala ndi mitsempha ya varicose, thrombophlebitis, pofuna kupewa thrombosis. Pali zovuta zina, ndipo simukuyenera kuyiwala za izi, mutha kuwononga m'mimba mwachangu ngati mumamwa mosasamala.
Wachiroma, wazaka 43, Perm
Njira yotsika mtengo kwa chilichonse, koma ndibwino kuti musagwiritse ntchito molakwika - pali contraindication ndi zotsatira zoyipa, ndikukulangizani kuti muwerenge malangizo mosamala. Kuyambira ndili mwana ndimagwiritsa ntchito mankhwala ochizira matenda a kupweteka panyumba kunyumba. Mankhwala othandiza kwa chimfine ndi malungo: Mapiritsi a 2 a Aspirin usiku ndikukulunga bwino. Chinthu chachikulu sikuti musiphonye mphindi ndikuyamba pomwe kuwonetsa chimfine. Ndimamwa ndimutu, ndikumva kupweteka kumbuyo kapena minofu. Ndimalilekerera bwino, koma idyani yaying'ono koma kangapo kamodzi.
