Langerin amagwiritsidwa ntchito kuchepetsa magazi. Awa ndi mankhwala a hypoglycemic ochokera pagulu la Biguanide. Amalembera mankhwalawa a shuga a mtundu wachiwiri, pamene insulin siyofunikira.
Dzinalo Losayenerana
Dzinalo limagwirizana ndi dzina lantchito - Metformin (metformin).
Langerin amagwiritsidwa ntchito kuchepetsa magazi.
ATX
Nambala ya ATX - nambala ya A10BA02.
Kutulutsa mafomu ndi kapangidwe kake
Mankhwalawa amapezeka mwa mawonekedwe a mapiritsi a pakamwa. Pali mitundu yotere - yophimba, yopanga nthawi yayitali, yophimbidwa ndi nembira yamafilimu, yophimba enteric.
Pulogalamu yofunika kwambiri ndi metformin hydrochloride. Omwe amapezekapo: wowuma chimanga, magnesium stearate, macrogol 6000, anhydrous colloidal silicon dioxide, povidone 40, titanium dioxide, starch sodium glycolate, hypromellose, monstearate-2000-macrogol.
Zotsatira za pharmacological
Mankhwalawa amachepetsa mapangidwe a glucose "watsopano" m'chiwindi, kuyamwa kwake m'mimba. Zabwino ndikuti sizikhudza kapangidwe ka insulin ndipo nthawi zambiri zimayambitsa mikhalidwe ya hypoglycemic.
Pharmacokinetics
Mukamamwa mankhwalawo mkati, mankhwalawa amamwa kwathunthu thirakiti, pomwe gawo limodzi limatuluka kuchokera m'thupi ndi ndowe. Kuchuluka kwazinthu kumatha kufikira maola awiri ndi theka. M'magazi, mankhwalawa sakhala ndi ma protein; mu ma cytoplasm a maselo ofiira, ma cell omwe amathandizira amadziunjikira monga ma granules.
Mpaka gawo limodzi mwa magawo atatu a mankhwalawa amachotsedwa m'thupi ndi ndowe.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito ngati vuto la kuperewera kwa mankhwala othandizira pakudya ndi masewera olimbitsa thupi, ali ndi glycemia yayikulu mu shuga ya mtundu wachiwiri, makamaka kunenepa kwambiri.
Contraindication
Metformin ndi yoletsedwa kugwiritsidwa ntchito pazinthu zotere:
- kuchuluka kwa zigawo zikuluzikulu;
- kwambiri mkhutu aimpso ndi kwa chiwindi ntchito;
- ndi zidakwa;
- ndi matenda a matenda opatsirana ndi mtima;
- mitundu yosiyanasiyana ya acidosis;
- mimba ndi mkaka wa m`mawere;
- kugwiritsa ntchito ayodini;
- ndi njala komanso kusowa kwamadzi.
Momwe mungatenge Langerin
Mankhwalawa amatengedwa poyang'anira kuchuluka kwa shuga m'magazi, omwe wodwalayo amayenera kuyeza kangapo patsiku: m'mawa, mutatha kudya chilichonse, madzulo asanagone.
Kulandila - pakamwa mukudya chakudya kapena mukatha. Mlingo woyambirira umachokera ku 500 mg mpaka 850 2 kapena katatu pa tsiku. Pambuyo pa masabata awiri, mlingo uyenera kusinthidwa malinga ndi zotsatira za kusanthula kwa glycemic.
Mlingo waukulu kwambiri sungadutse 3000 mg, umagawidwa katatu.
Kwa ana atatha zaka 10, mlingo ndi 500-850 mg patsiku 1 nthawi imodzi. Mlingo wapamwamba ndi 2000 mg, wogawidwa ndi 2-3.
Ndi matenda ashuga
Malangizo ogwiritsira ntchito amagawa mankhwalawa kukhala monotherapy komanso kuphatikizana ndi insulin. Mlingo woyambirira ndi 500-850 mg kawiri tsiku lililonse kapena mutadya. Patatha milungu iwiri, kusintha kwa mlingo kumachitika malinga ndi zotsatira za kuwongolera shuga. Nthawi yonseyi, wodwalayo ayenera kukhala ndi mbiri ya glycemic. Mlingo wovomerezeka waukulu ndi 3 g, womwe umagawidwa 3 Mlingo.
Mu shuga mellitus, malangizo ogwiritsira ntchito mankhwalawa amagawa mankhwalawo kukhala monotherapy komanso kuphatikiza ndi insulin.
Zotsatira zoyipa za Langerin
Zochitika zoyipa kuchokera ku ziwalo ndi machitidwe osiyanasiyana zimatha kukhazikika.
- Khungu: kuzimiririka, ming'oma.
- Zokhudza hepatobiliary dongosolo: chiwindi, chiwindi ntchito.
- Zizindikiro zamitsempha: zovuta zamakomedwe.
- Kuchokera pamimba: kukhudzidwa ndi mseru, kusanza, kutsegula m'mimba, kusowa kwa chakudya, kupweteka kwam'mimba, kutulutsa, kulawa zitsulo mkamwa.
- Palibe kawirikawiri kusintha kwa magazi - megaloblastic anemia, kuchepa kwa vitamini B12.
Mawonetseredwe azachipatala amadzisowa pawokha atasiya mankhwala. Nthawi zina, mankhwala achiwonetsero amafunikira.
Zokhudza mphamvu pakuwongolera njira
Mukamagwiritsa ntchito Langerin monga monotherapy, pamakhala chiwopsezo chochepa kwambiri chotengera matenda a hypoglycemic, akaphatikizidwa ndi mankhwala ena omwe amachepetsa shuga, amawonjezeka. Chifukwa chake, ndizotheka kuchepetsa chidwi mukamagwira ntchito ndi ziwiya kapena poyendetsa.
Malangizo apadera
Amakhala ndi kusintha mlingo (nthawi zambiri piritsi limagawidwa m'magulu awiri) ndikuphunzira kuthekera kwa kusankha kwake m'magulu osiyanasiyana a anthu.
Gwiritsani ntchito mu ukalamba
Mwa anthu achikulire, magwiridwe antchito a machitidwe ambiri (impso, kukanika kwa mtima) nthawi zambiri amavutika, kotero odwala ambiri amagwiritsa ntchito mankhwala kuti azisamalira. Ndipo ngati pali kusagwirizana kwa mankhwalawa, ndiye kuti muyenera kusiyira Langerin kapena kusintha mlingo wake (ngati kuli kotheka, gawanani piritsi pakati, mutenge chimodzi).
Kupatsa ana
Mankhwalawa amalembera ana opitirira zaka khumi. Ali aang'ono, mankhwala ena amasankhidwa. Kuyesedwa kwa mankhwalawa muubwana sikunachitike, kotero palibe deta pazomwe zimakhudza kukula, kukula ndi kutha kwa ana, makamaka nthawi yayitali. Chifukwa chake, iyenera kugwiritsidwa ntchito mosamala mu gulu la zaka zapakati pa 10-12.
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pokonzekera kutenga pakati, muyenera kusiya kumwa Langerin ndikudziwitsa dokotala za izi. Adziwitsanso kuchuluka kwa insulini, yomwe idzafunika kugwiritsidwa ntchito nthawi yonse ya bere. Zotsatira za metformin pa mwana wosabadwayo zimayikidwa m'gulu B.
Pokonzekera kutenga pakati, muyenera kusiya kumwa Langerin ndikudziwitsa dokotala za izi.
Kafukufuku pa nthawi yoyamwitsa sanayendetsedwe, palibe deta pakulowerera kwa metabolites mu mkaka, chifukwa chake, panthawi yoyatsa, muyenera kusiya mankhwalawa.
The ntchito aimpso kuwonongeka
Pankhani ya kuwonongeka kwa impso, kuyesedwa koyenera kuyenera kuchitidwa kuti mupeze mulingo wa creatinine ndi urea. Malinga ndi zotsatira zake, mlingo wa mankhwalawo umasinthidwa kapena kusiyidwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Ndikofunikira kuyang'anira momwe chiwindi chirili. Ndi kuwonongeka, mankhwalawa ayenera kuthetsedwa, chifukwa chiopsezo chokhala ndi lactic acidosis ndi chambiri. Nthawi zina, ndikotheka kusintha kuchuluka kwa mankhwalawa moyang'aniridwa ndi dokotala.
Mankhwala osokoneza bongo a langerin
Mukamagwiritsa ntchito mlingo wokwanira kuposa momwe muyenera, zimakhazikika: lactic acidosis, kumva kupweteka pakamwa, mucous membrane, khungu, kupweteka m'misempha ndi chifuwa, kupumira mwachangu, kusokonezeka kwa kugona, kusowa kwa magazi, kusokonezeka kwa mitsempha, kupweteka kwam'mimba, kusanza, kusokonekera kwa mtima, oliguria, ICE. Kuphatikiza apo, zinthu za hypoglycemic sizikukula. Palibe chithandizo chamankhwala. Monga chithandizo, dialysis ndi hemodialysis zimagwiritsidwa ntchito bwino, ndipo chithandizo chamankhwala chimachitidwanso. Kuchotsera mankhwala mwachangu ndikofunikira.
Kuchita ndi mankhwala ena
Pali nthawi zina pomwe mankhwala amathandizirana pazotsatira zawo ndikuchepetsa shuga - ichi ndi chiopsezo. Chifukwa chake, kuphatikiza kwina kumatha kuletsedwa kapena kugwiritsidwa ntchito ngati chinthu chofunikira kwambiri.
Kuphatikiza kophatikizidwa
Ngati kuli kofunikira kuchita njira yomwe mankhwala ogwiritsa ntchito ayodini angagwiritsidwe ntchito, muyenera kusiya kumwa Langerin m'masiku awiri. Ndipo kuyambiranso kwa mankhwalawa ndikotheka patatha masiku awiri atatha kafukufukuyu, izi zisanachitike, kuyesedwa kuyenera kuchitidwa kuti muwone momwe matendawa amathandizira. Kupanda kutero, amayamba kulephera aimpso, chiopsezo cha lactic acidosis.
Glformin ikhoza kukhala chithunzi cha mankhwalawa.
Mankhwala Danazol sagwiritsidwa ntchito pochiza Langerin. Izi ndizodzaza ndi shuga wambiri, acidosis, komanso chiopsezo chokhala ndi chikomokere. Chifukwa chake, glycemia iyenera kuyang'aniridwa.
Osavomerezeka kuphatikiza
Mukamamwa Langerin, sikulimbikitsidwa kumwa mowa kapena zakumwa zina ndi zinthu zokhala ndi mowa.
Kuphatikiza komwe kumafunikira kusamala
Mosamala kwambiri, mankhwalawa amayenera kugwiritsidwa ntchito limodzi ndi glucocorticosteroids a systemic kapena topical glucocorticosteroids, ma Aester inhibitors, diuretics, beta-2-sympathomimetics - magulu awa a mankhwala amatha kuchepetsa shuga m'magazi. Chifukwa chake, muyenera kuchenjeza wodwala za izi, komanso kusintha mlingo wa Langerin.
Chlorpromazine ndi antipsychotic alinso mankhwala, mogwirizana ndi momwe mankhwalawa amagwiritsidwa ntchito popangira metformin.
Kuyenderana ndi mowa
Sizigwirizana ndi mowa. Akaphatikizidwa ndi ethanol, chiopsezo chokhala ndi boma lactic acidotic chimakulirakulira, makamaka ndi mavuto ndi chiwindi (kulephera kwa chiwindi) kapena kuperewera kwa chakudya choperewera.
Analogi
Malonda a Langerin ndi mankhwalawa:
- Glyformin;
- Kutalika kwa Gliformin;
- Glucophage;
- Metformin;
- Metfogamm;
- Fomu;
- Siofor mu mitundu yosiyanasiyana (1000, 800, 500);
- Vero-Metformin;
- Glycomet 500.
Kupita kwina mankhwala
Mankhwalawa amaloledwa kuikidwa.
Kodi ndingagule popanda kulandira mankhwala?
Masamba ena amapereka kugula mankhwala osagwiritsa ntchito mankhwala, koma ndi mankhwala.
Mtengo wa Langerin
Mtengo umasiyanasiyana kuchokera ku ruble 100 mpaka 700., Kutengera mlingo. Mtengo wa analogi ndiwosiyana.
Zosungidwa zamankhwala
Iyenera kusungidwa kuchokera kwa ana, zovuta zapadera sizofunikira.
Tsiku lotha ntchito
Amasungidwa kwa zaka 5.
Wopanga
Wopanga ndi JSC "Zentiva", yomwe ili ku Slovak Republic, Hlohovec, ul. Nitryanskaya 100.
Ndemanga za Langerin
Anton, wazaka 48, Orel: "Ndakhala ndikudwala matenda ashuga a 2 kwa zaka 3. Dotolo wandiwuza mankhwalawa. Ndili wokondwa kuti palibe zotsatila zake, ndipo mulingo wa shuga sukukwera."
Anna, wazaka 31, ku Moscow: "Ndili ndi matenda a shuga a 2, ndadwala pafupifupi zaka 5. Chaka choyamba ndinakhala ndimagulu a glucose mwakuchita masewera olimbitsa thupi komanso kudya. Komabe, sizinathandize kwenikweni. Dotolo adapereka mankhwala awa pa 850 mg kawiri patsiku. Palibe zoyipa. "
Vasily, wazaka 28, Krasnodar: "Matenda a shuga a Type 2 adapezeka koposa chaka chapitacho. Ndikutenga mankhwalawa. Dotolo adatinso amagwira ntchito bwino ndipo amawonjezera kuchuluka kwa glucose. Adasankha kuchuluka kwa 500 mg. Mankhwalawa amayenera kukhala osaneneka chifukwa chake ndikuganiza kuti mankhwalawa ndiabwino. "
