Mankhwala Siofor kapena Metformin ndi mitundu iwiri yofananira yomwe ili ndi metformin yofanana yogwiritsira ntchito. Kutchuka kwawo kumachitika chifukwa chakuti amawongolera kuchuluka kwa magazi, kuchotsa cholesterol "yoyipa", kulimbitsa makoma amitsempha yamagazi, ndikuchepetsa chiopsezo cha matenda a mtima. Popeza gawo lalikulu ndi la mndandanda wa biguanide, kuikidwa kwake kumawonetsedwa kwa odwala matenda a shuga komanso kunenepa kwambiri komwe kumayenderana ndi matendawa.
Kodi Siofor amagwira ntchito bwanji?
Mapiritsi a Siofor ndi mankhwala amphamvu omwe amangoperekedwa ndi adokotala. Amawonetsedwa kwa odwala matenda ashuga kuti achepetse shuga.
Mankhwala Siofor kapena Metformin ndi mitundu iwiri yofananira yomwe ili ndi metformin yofanana yogwiritsira ntchito.
Mapangidwe a piritsi:
- metformin hydrochloride (cholowetsa insulin chomwe cholinga chake ndi kuphatikiza shuga);
- magnesium wakuba;
- titanium dioxide;
- macrogol;
- povidone;
- chopondera ndi hypromellose.
Zisonyezero zosankhidwa:
- mtundu wa 2 matenda a shuga;
- kunenepa
- endocrine kusabereka, wopezeka kuphwanya ntchito za endocrine glands motsutsana shuga;
- Kubwezeretsa metabolic njira.
Zogwirizana ndi:
- matenda a kupuma dongosolo;
- kuledzera;
- mavuto obwera pambuyo pake;
- oncology;
- matenda a mtima;
- tsankho;
- impso ndi chiwindi kukomoka pachimake;
- mimba
- nthawi yotsekera;
- ana ndi ukalamba.
Siofor amatchulidwa zochizira matenda amitundu iwiri.
Malangizo apadera omwera mankhwalawa:
- Kugwiritsa ntchito nthawi yayitali kumathandizira kuti khungu la vitamini B12 lisamayende bwino, wofunikira mu hematopoiesis;
- osagwira mu mtundu 1 wa shuga;
- mavuto obwera chifukwa cha kuchuluka kwa kuchuluka kwa mankhwalawa, zizindikiro za chifuwa (kuyabwa, kuyabwa, kutupa) ndi kudzimbidwa (kusanza, kutsegula m'mimba, kudzimbidwa).
Katundu wa Metformin
Mankhwala ochepetsa shuga amenewa amapangidwa m'mapiritsi, omwe amaphatikizanso metformin yogwira ntchito, komanso zigawo zothandiza:
- magnesium wakuba;
- titanium dioxide;
- macrogol;
- povidone;
- crospovidone;
- omanga - talc ndi wowuma;
- eudragit chipolopolo.
Nthawi yake:
- kuchepetsa shuga mu mono - kapena zovuta mankhwala;
- shuga mellitus mu mawonekedwe amadalira insulin;
- metabolic syndrome (kuchuluka kwa mafuta ochulukirapo);
- matenda a carbohydrate;
- kuphwanya lipid ndi purine metabolism;
- matenda oopsa;
- scleropolycystic ovary.
Contraindication kuti agwiritse ntchito:
- kusamukira acid-base bwino (pachimake acidosis);
- hypoxia;
- kulephera kwa mtima;
- myocardial infarction;
- matenda a mtima;
- tsankho;
- aimpso ndi chiwindi kulephera;
- mimba
- nthawi yotsekera;
- ana ndi ukalamba.
Zotsatira zoyipa zomwe zimachitika chifukwa cha tsankho la metformin ndi zinthu zina:
- mavuto am'mimba (m'mimba, kutulutsa, kusanza);
- kusintha kwa kukoma (kupezeka kwa kukoma kwazitsulo);
- kuchepa magazi
- matenda a anorexia;
- hypoglycemia;
- kukula kwa lactic acidosis (kuwonetsedwa ndi kuwonongeka kwaimpso);
- Zotsatira zoyipa za m'mimba.
Kuyerekeza kwa Siofor ndi Metformin
Mankhwala amodzi amawerengedwa kuti amafanana ndi enanso, chifukwa chophatikizira chachikulu ndicho metformin yofanana. Kuyerekeza kwawo ndikosatheka. Titha kungolankhula za njira yomweyo zogwirira ntchito ndi ena opanga omwe amaliza kapangidwe kake ndi zinthu zina zowonjezera ndikupereka mayina osiyanasiyana ogulitsa.
Kufanana
Kufanana kwakukulu kwa ma biguanides munjira ndi kuwongolera kachitidwe. Kuyesetsa kumapangidwa ndikuwongolera magwiridwe antchito a metabolic panthawi ya ma cell, pomwe thupi limayamba kugwirana ndi insulin mwanjira yomwe imapangitsa kuchepetsa pang'onopang'ono mlingo wa tsiku ndi tsiku mpaka kusiyidwa kwathunthu. The pharmacological zochita za yogwira ntchito lagona kugona kwake kuchepetsa kuchuluka kwa shuga m'magazi a magazi ndi gluconeogeneis (kupondereza mapangidwe a shuga mu chiwindi).
Metformin imayambitsa enzyme yapadera ya chiwindi (protein kinase), yomwe imayang'anira izi. Kupanga kwa activation ya proteinasease sikumvetseka kwathunthu, komabe, kafukufuku wambiri akuwonetsa kuti chinthuchi chimabwezeretsa kupanga kwa insulin mwanjira yachilengedwe (chimagwira monga chizindikiro cha insulin chomwe chimaphatikizapo njira za metabolism zamafuta ndi shuga).
Mankhwala ali ndi mitundu yofananira ya piritsi. Ma voliyumu awo ndi 500, 850 ndi 1000 mg. Kugwiritsa ntchito ndalama kumachitika chimodzimodzi. Maphunzirowa aperekedwa m'magawo:
- koyamba mankhwalawa - piritsi 1 500 mg kawiri pa tsiku;
- Pambuyo pa masabata 1-2, mlingo umachulukitsa 2 kawiri (monga momwe dokotala wanenera), omwe ndi ma 4 ma PC. 500 mg aliyense;
- kuchuluka kwake kwa mankhwalawa ndi mapiritsi 6 a 500 mg (kapena zidutswa zitatu za 1000 mg) patsiku, i.e. 3000 mg
Metformin siilimbikitsidwa kwa anyamata akamakula.
Zotsatira za Metformin kapena Siofor:
- insulin kukana kumachepa;
- kuchuluka kwa chidwi ndi kuchuluka kwa shuga;
- matumbo a shuga m'magazi amachedwetsedwa;
- kuchuluka kwa cholesterol matenda, zomwe zimalepheretsa kukula kwa thrombosis mu shuga;
- kuwonda kumayamba.
Ma Metformins salimbikitsidwa kwa anyamata akamakula, chifukwa mankhwalawa amachepetsa dihydrotestosterone, mawonekedwe omwe amagwira a testosterone yamamuna, omwe amachititsa kukula kwa thupi kwa achinyamata.
Kodi pali kusiyana kotani?
Kusiyana pakati pa mankhwalawo ndi dzina (zomwe zimatengera wopanga) ndi zina zomwe zikuphatikizidwa ndizinthu zina. Kutengera ndi zomwe zigawo zothandizira zomwe zili m'maphatikizidwe, othandizira awa ayenera kuyikidwa. Chifukwa chake crospovidone, yomwe ndi gawo limodzi mwa mankhwalawo, imapangitsa kuti mapiritsi azisungika umphumphu wawo, ndipo nthawi yomweyo amagwiritsidwa ntchito kuti amasule zinthu zomwe zikuyenda bwino pazomwe zimapangidwa. Pakukhudzana ndi madzi, gawo ili limatupa ndikusungirabe mphamvu iyi mutayanika.
Siofor ndi mankhwala a kampani ya Germany Berlin-Chemie / Menarini Pharma GmbH.
Siofor ndi mankhwala a kampani ya Germany Berlin-Chemie / Menarini Pharma GmbH. Mankhwalawa amaperekedwa pansi pa mtundu wotere osati ku Russia kokha, komanso ku mayiko onse aku Europe. Metformin ili ndi ambiri opanga osiyanasiyana, motero, ndikusintha mu dzina:
- Metformin Richter (Hungary);
- Metformin-Teva (Israel);
- Metformin Zentiva (Czech Republic);
- Metformin-Canon (Russia).
Siofor ndi Metformin zimasiyana pamtengo.
Chotsika mtengo ndi chiyani?
Mtengo wapakati wa mapiritsi a Siofor No. 60 okhala ndi kipimo:
- 500 mg - 210 ma ruble;
- 850 mg - 280 ma ruble;
- 1000 mg - 342 rub.
Mtengo wamba wa mapiritsi a Metformin No. 60 (kutengera wopanga):
- Richter 500 mg - ma ruble 159., 850 mg - 193 ma ruble., 1000 mg - 208 ma ruble .;
- Teva 500 mg - 223 rubles, 850 mg - 260 rubles, 1000 mg - 278 rubles.;
- Zentiva 500 mg - 118 ma ruble, 850 mg - 140 rubles, 1000 mg - 176 rubles.;
- Canon 500 mg - 127 ma ruble, 850 mg - 150 ma ruble, 1000 mg - 186 rubles.
Siofor, Metformin amalembedwa ngati cholowa m'malo mwazonse, chifukwa chake, sikoyenera kusiyanitsa kuthekera kwawo - ichi ndi chimodzi.
Kodi ndibwino kuti Siofor kapena Metformin?
Mankhwala amathandizidwa kuti asinthane ndi wina ndi mnzake, chifukwa chake sikoyenera kusiyanitsa kuthekera kwawo - ali chimodzimodzi. Koma kapangidwe kake ndi kabwino - dotoloyo apanga chisankho pamayendedwe akuwonetsa za matendawa, kuzindikira zina zowonjezera, zomwe munthu amakonda zomwe wodwalayo amakonda. Mankhwalawa onse amathandizira matenda amtundu wa 2 komanso amathandizira kunenepa - izi ndizofunikira kwambiri posankha Biguanides Siofor ndi Metformin.
Ndi matenda ashuga
Pogwiritsa ntchito mankhwala a metformin, mutha kutsika ndi glucose ndi 20%. Poyerekeza ndi mankhwala ambiri omwe amagwiritsidwa ntchito pochiza matenda ashuga, izi zimachepetsa chiopsezo cha matenda amtima ndi kufa kwa odwala omwe ali ndi matenda a shuga a mtundu wachiwiri. Matendawa ndi ovuta kuchiza. Koma ngati matenda atha kutsimikizika mwachangu komanso mwachangu kuyamba mankhwala, ndiye kuti pali mwayi wakuchira popanda zotsatira.
Zomwe zimaperekedwa ndi ma genuanide othandizira awa zimawonetsedwa kwa odwala omwe amadalira jakisoni wa insulin, komanso amagwiritsidwa ntchito ngati prophylaxis popewa matenda a shuga. Nyimbozo zimayamba ntchito yawo nthawi yomweyo, kuyambira pomwe amalandila oyambilira amasintha machitidwe onse. Kugwiritsa ntchito Metformin kapena Siofor pafupipafupi, chithandizo chofanana ndi Insulin sichidzafunika posachedwa, majakisoni amatha m'malo mwake ndikungotenga ma biguanides okha.
Kuchepetsa thupi
Mankhwalawa tikulimbikitsidwa kuti atengedwe mu zovuta zochizira kulemera kwakukulu, zomwe zimakhudza thupi, zimayambitsa zovuta za mtima, komanso kuchuluka kwa shuga m'magazi.
Mothandizidwa ndi Biguanides:
- kuchepa kwa chakudya;
- shuga wambiri amasiya zakudya;
- zopatsa mphamvu zimachepa;
- kagayidwe imayendetsedwa;
- Kuchepetsa thupi kumabwera (onani kuchepa kwa 1-2 makilogalamu kulemera masiku onse a 5-7).
Pochita mankhwala, muyenera:
- kutsatira zakudya;
- kukana zakudya zamafuta;
- kulumikiza zolimbitsa thupi.
Ndemanga za Odwala
Mary, wazaka 30, mzinda wa Podolsk.
Siofor amathandiza kutaya makilogalamu 3-8 pamwezi, chifukwa chake ndiotchuka. Mankhwalawa ndi oyenera kwa iwo omwe sangathe kuleketsa zakudya zosiyanasiyana. Mutha kugwiritsa ntchito njira yokhazikika yolimbana ndi vuto la maswiti - mankhwalawa amapereka izi.
Tatyana, wazaka 37, Murmansk.
Metformin imayikidwa ngati matenda ashuga ndi omwe amachititsa kwambiri kunenepa. Kunenepa kwambiri mu matenda ena (chithokomiro cha chithokomiro, kukanika kwa mahomoni, ndi zina zotere) samathandizidwa ndi chinthuchi. Adatero dokotala. Musanadzipange nokha, pezani chomwe chimayambitsa.
Olga, wazaka 45, Kaliningrad.
Metformin kapena Siofor osagwiritsidwa ntchito mosasamala amatha kubzala chiwindi. Poyamba, iye sanazindikire kufunika kwa zosokoneza zotere mpaka atapereka chidwi ndi kulemera mbali yakumanja komanso kutsutsana kwa mapuloteni amaso. Osadzilamula nokha.
Metformin ndi Siofor amalimbikitsa kumwa mankhwalawa kunenepa kwambiri.
Ndemanga za madotolo za Siofor ndi Metformin
K.P. Titov, wothandizira, Tver.
Metformin ndi INN, ndipo Siofor ndi dzina lamalonda. Ndi mankhwala ati omwe ndi othandiza kwambiri palibe amene anganene. Zomwe zimapangitsa kuti magwiridwe antchito azigwira bwino ntchito kapena osagwira bwino ntchito zimatha kukhala zosiyana, kuyambira zolakwika zamakonzedwe mpaka kufunikira kophatikizana ndi gulu lina la mankhwala omwe amathandizira pakuchita kwa biguanides.
S.A. Krasnova, endocrinologist, Moscow.
Metformin sigwira ntchito ngati mankhwala ochepetsa shuga, imayikidwa kuti iwonjezere insulin. Chifukwa chake, palibe hypoglycemic coma kuchokera kwa iye, pomwe shuga amatsika kwambiri kotero kuti wodwalayo amatha kuwonongeka. Izi ndizosaphatikizika pazinthu zopangidwa ndi metformin.
O.V. Petrenko, wothandizira, Tula.
Metformin Zentiva yotsika mtengo ndiyotchuka kwambiri, koma ngakhale shuga wazindikira si chifukwa chomwa mapiritsi. Pogwiritsa ntchito nthawi yayitali, gulu la Biguanide limachepetsa kulolerana kwa chitetezo cha mthupi kwa antigen opangidwa. Ndikwabwino kuonanso zakudyazo, kupatula zakudya zoyipa pamenyu, ndikuwonjezera zathanzi. Zakudyazo ziyenera kukhala ndi zipatso komanso masamba ambiri. Kumbukirani kuti kudzichitira nokha koletsedwa.
