Neurontin 300 ndi mankhwala omwe ali m'gulu la mankhwalawa othandizira matenda omwe amaperekedwa ndi matenda opatsirana. Imakhala ndi zotsutsana ndi zoyipa, chifukwa chake ziyenera kugwiritsidwa ntchito moyang'aniridwa ndi dokotala.
Dzinalo Losayenerana
Gabapentin
Neurontin 300 ndi mankhwala omwe ali m'gulu la mankhwalawa othandizira matenda omwe amaperekedwa ndi matenda opatsirana.
ATX
N03AX12
Kutulutsa mafomu ndi kapangidwe kake
Mankhwala ali ndi mawonekedwe a mapiritsi okhala ndi filimu yoyera yofiirira., Omwe amakhala ndi mawonekedwe owundana, a biconvex. Pa dzanja limodzi pali ngozi yogawanika. Piritsi lililonse lili ndi:
- gabapentin (300 mg);
- shuga mkaka monohydrate;
- wowuma mbatata;
- titanium dioxide;
- talc;
- magnesium wakuba;
- cellulose ufa.
Mapiritsi amaperekedwa m'maselo a contour a zidutswa 10, zomwe zimayikidwa m'makatoni. Bokosilo likhoza kuphatikiza 2, 5 kapena 10 matuza ndi malangizo.
Mapiritsi amaperekedwa m'maselo a contour a zidutswa 10, zomwe zimayikidwa m'makatoni.
Zotsatira za pharmacological
Gabapentin ali ndi izi:
- ili ndi kapangidwe kofanana ndi gamma-aminobutyric acid, koma momwe amagwirira ntchito ndi osiyana ndi mankhwala ena antiepileptic omwe amagwira pa GABA receptors;
- imamangirira zigawo zamagetsi odalira mphamvu yamagetsi, kupondereza kachitidwe ka calcium ion, zomwe zimapangitsa kuti pakhale kupweteka kwa neuropathic;
- amachepetsa kuwononga kwa glutamate-amadalira ma neurons, kumawonjezera kupanga kwa gamma-aminobutyric acid, amalepheretsa kuphatikizika kwa monoamine neurotransmitters;
- sichikhudzana ndi ma receptor ama anticonvulsants ena kapena ma neurotransmitters;
- Imafooketsa zochita za glutamate receptor agonist;
- amachepetsa kupanga kwa monoamine neurotransmitters;
- imathandizira kagayidwe ka gamma-aminobutyric acid mu minyewa yaubongo;
- imalepheretsa kukulitsa khunyu yoyambitsidwa ndi ma electroshock, mankhwala amtundu ndi matenda amtundu.
Pharmacokinetics
Ndi pakamwa, makonzedwe apamwamba a plasma ambiri a gabapentin amapezeka pambuyo pa maola atatu. Kudya sikukhudza kuyamwa kwa zinthu zomwe zimagwira.
Mu thupi la munthu, mankhwalawa samapangidwa. Hafu ya mlingo wotengedwa umapangidwa pang'onopang'ono mkati mwa maola 6. Mlingo wambiri wotengedwa umachoka m'thupi ndi mkodzo osasinthika.
Zizindikiro zogwiritsidwa ntchito
Mankhwalawa amagwiritsidwa ntchito:
- neuropathies mu odwala akulu;
- monotherapy yachiwiri ya kukomoka kwa odwala opitirira zaka 12;
- Pamodzi mankhwala a sekondale kukhudzana akuluakulu ndi ana okulirapo zaka 3.
Contraindication
Neurontin sagwiritsidwa ntchito pokhudzana ndi matupi a gwirapentin ndi mankhwala othandizira a mankhwalawa.
Ndi chisamaliro
Zotsatira zokhudzana ndi kugwiritsidwa ntchito kwa anticonvulsant ndi matenda obisika a dongosolo omwe amachedwetsa impso kuwonekera kwa gabapentin.
Momwe mungatenge Neurontin 300
Mlingo wa mankhwala zimatengera mtundu wa matenda:
- Neuropathy. Chithandizo cha mankhwalawa chimayamba ndi kuyambitsa kwa 900 mg patsiku. Mlingo wa tsiku ndi tsiku umagawidwa m'magulu atatu. Kutengera mphamvu ya mankhwalawa, mlingo umatha kuwonjezeka mpaka 3 g patsiku.
- Kukakamira pang'ono mwa odwala osakwana zaka 18. Mlingo wovomerezeka tsiku lililonse ndi 600 mg. Ngati palibe zotsatirapo, zimachulukitsidwa mpaka 1.8 g.
- Kukakamizidwa pang'ono. 900-3600 mg wa gabapentin amatengedwa patsiku. Ndi kulekerera kwakanthawi kwamankhwala komanso pafupipafupi kukomoka, tsiku lililonse mlingo umakulitsidwa mpaka 4,8 g. Kutalikirana pakati pa mapiritsi pogawa tsiku ndi tsiku zigawo zitatu sikuyenera kupitirira maola 12.
- Matenda a Convulsive mu ana a zaka 3-12. Chithandizo chimayamba ndi kuyambitsa 10-15 mg / kg patsiku. Mlingo wa tsiku ndi tsiku umagawika m'magulu atatu ofanana. Mapiritsi amaperekedwa kwa mwana maola 8 aliwonse. Pakupita masiku atatu, mlingo umakulitsidwa pang'onopang'ono mpaka 25-30 mg / kg. Pogwiritsa ntchito nthawi yayitali, mphamvu ya mankhwalawa imatha kuchepa, zomwe zimafunikira kuwonjezeka kwa mlingo mpaka 50-100 mg / kg.
Ndi matenda ashuga
Ndi chitukuko cha kukomoka kwa odwala matenda a shuga, kusintha kwa mankhwalawa sikofunikira, komabe, chithandizo chikuyenera kuchitika moyang'aniridwa ndi dokotala.
Ndi chitukuko cha kukomoka kwa odwala matenda a shuga, kusintha kwa mankhwalawa sikofunikira, komabe, chithandizo chikuyenera kuchitika moyang'aniridwa ndi dokotala.
Zotsatira zoyipa za Neurotonin 300
Mankhwalawa amatha kuyambitsa mavuto omwe amabwera chifukwa cha kuwonongeka kwa ziwalo zosiyanasiyana.
Matumbo
Kugonjetsedwa kwa dongosolo logaya chakudya kumawonetsedwa:
- kuchuluka kwa mpweya;
- kuchepa kwa chakudya;
- matenda a chingamu;
- kuwonongeka kwa mano enamel;
- kulakalaka;
- youma mucous nembanemba zamkamwa;
- kupweteka m'dera la epigastric;
- kusanza.
Hematopoietic ziwalo
Mankhwala ziletsa ntchito ya hematopoietic dongosolo, zomwe zimabweretsa kuchepa kwa kuchuluka kwa leukocytes ndi kukula kwa hemorrhagic zovuta.
Pakati mantha dongosolo
Ngati mankhwalawa akhudza dongosolo lamanjenje, pali:
- mutu
- Chizungulire
- kuchuluka kukondwerera kwa magalimoto;
- kusowa kwa Reflex;
- sedation ndi kugona;
- kuphwanya ntchito za mphamvu (kuchepa kwa zowona ndi kumva, kusintha kwa kukoma)
- kusunthira kwadzidzidzi kwa ma eyeb eye;
- mayiko achisoni;
- kusokonezeka kwa kukumbukira;
- chikumbumtima;
- kusakhazikika mtima;
- malingaliro operewera;
- miyendo yanjenjemera;
- kupuma.
Kuchokera kwamikodzo
Mankhwala amawonjezera chiopsezo cha cystitis ndi pyelonephritis.
Kuchokera ku minculoskeletal system
Kutengera zakomwe mutatenga Neurontin, mutha kukumana:
- kupweteka kwa minofu ndi molumikizana;
- zovuta zam'magazi;
- kupweteka kwa msana.
Pa khungu
Mukamamwa anticonvulsant, zotupa pakhungu, urticaria, zotupa pa mankhwala, pustular totupa.
Matupi omaliza
Kugwiritsa ntchito Neurontin kumatha kubweretsa mawonekedwe a chifuwa cham'mimba ndi mphuno yothina, edema ya Quincke, eosinophilia, mantha a anaphylactic.
Zokhudza mphamvu pakuwongolera njira
Mankhwalawa akhoza kuthana ndi magwiridwe antchito amitsempha yamagazi, kuchepetsa nkhawa komanso kuthamanga kwa zomwe zimachitika, motero munthawi yamankhwala amakana kugwira ntchito ndi njira zovuta.
Malangizo apadera
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Pa nthawi yoyembekezera, Neurontin imayikidwa pokhapokha ngati anticonvulsants otetezeka sagwira ntchito. Gabapentin amalowa mkaka, chifukwa cha mankhwalawa, mwanayo amasinthidwa kuti adyetsedwe.
Kupangira mankhwala am'mimba kwa ana 300
Mapiritsi sayenera kuperekedwa kwa odwala ochepera zaka zitatu.
Gwiritsani ntchito mu ukalamba
Mukamapereka mankhwala kwa achikulire ndi a senile, kuthekera kwa kukhalapo kwa ma pathologies ofunikira kusintha kwa mankhwala kumaganiziridwa.
Kuchuluka kwa Neurotonin 300
Kupha poizoni kumachitika pogwiritsa ntchito zoposa 5 g ya gabapentin. Imaphatikizidwa ndi chizungulire, diplopia, ulesi ndi zotayirira zotayirira. Pofuna kuchepetsa matenda, Ndi kuvulala kwambiri aimpso, mankhwalawa amachotsedwa m'thupi ndi hemodialysis.
Kuchita ndi mankhwala ena
Morphine amachepetsa mayamwidwe a gabapentin, kuchepetsa ntchito yake yotsutsana. Mankhwala sayanjana ndi phenytoin, phenobarbital, valproic acid. Pogwiritsa ntchito nthawi yomweyo limodzi ndi njira zakulera zophatikizira pakamwa, kugwira ntchito kwake kumapeto kumatha kuchepa. Maantacidin amachedwetsa kuyamwa kwa Neurontin. Probenecid sasintha magawo a pharmacokinetic a gabapentin.
Kuyenderana ndi mowa
Kumwa mowa panthawi ya chithandizo kumakulitsa mwayi wokhala ndi zotsatirapo zamagetsi.
Analogi
Zowonjezera m'malo a Neurontin ndi:
- Convalis;
- Katena
- Gabagamm
- Tebantin.
Kupita kwina mankhwala
Ndizosatheka kugula mankhwala anticonvulsant popanda mankhwala.
Mtengo wa Neurontin 300
Mtengo wapakati wa mapiritsi 100 ndi ma ruble 1,500.
Zosungidwa zamankhwala
Mapiritsiwa amawasunga m'mawu awo oyamba, kuwateteza ku kuwunika ndi chinyezi.
Tsiku lotha ntchito
Neurontin ndi yoyenera kugwiritsidwa ntchito mkati mwa miyezi 24 kuyambira tsiku lotulutsidwa.
Neurontin ndi yoyenera kugwiritsidwa ntchito mkati mwa miyezi 24 kuyambira tsiku lotulutsidwa.
Wopanga
Mankhwalawa amapangidwa ndi kampani yopanga mankhwala Pfizer, USA.
Ndemanga za Neurontin 300
Maria, wazaka 58, Ryazan: "Katswiri wofufuza zamitsempha amamuwuza mayi kuti ayambe kuyenda ndi mitsempha m'miyendo ndi m'miyendo. Kwa nthawi yayitali samatha kudziwa chomwe chimayambitsa kupweteka, kupenda kwathunthu komwe kunathandizira kuzindikira kutupikana kwamitsempha yam'mawa. ululu unayamba kuchepa. Amayi anayamba kulimbikira, kugwira ntchito zapakhomo. Atatha maphunziro a miyezi itatu, ululuwu unatheratu. "
Svetlana, wa zaka 38, ku St. kwa mankhwala, mwana wamkazi akukhala moyo wabwinobwino. "
