Novapim ndi mankhwala oteteza khungu ku matenda opatsirana, kupatsirana kwamkati ndi mawonekedwe a khungu.
Dzinalo Losayenerana
Cefepime.
ATX
J01DE01 - ogwiritsa ntchito antimicrobial.
Novapim ndi mankhwala oteteza khungu ku matenda opatsirana, kupatsirana kwamkati ndi mawonekedwe a khungu.
Kutulutsa mafomu ndi kapangidwe kake
Maantibayotiki amapangidwa ndi ufa, pomwepo njira yothetsera jakisoni. Mtundu wa ufa ndi woyera kapena wachikasu. Njira yotsirizidwa ndiyopepuka, yachikasu.
Zinthu zazikulu ndi cefepime chloride ndi L-arginine 500 mg kapena 1000 mg iliyonse.
Zotsatira za pharmacological
Awa ndi antibacterial mankhwala a gulu la IV m'badwo wa cephalosporins. Zikuwonetsa kuyesedwa motsutsana ndi gramu-gramu komanso gram-hasi tizilombo. Zochita za mankhwala zimachepetsa kaphatikizidwe kamtundu wa cell:
- gram-zabwino aerobes: Streptococcus viridans, Staphylococcus epidermidis, Staphylococcus aureus, ndi zina zovuta za staphylococci;
- gram-hasi aerobic tizilombo: Serratia, Acinetobacter calcoaceticus, Staphylococcus epidermidis, H. rarainfluenzae;
- Tizilombo toyambitsa matenda a anaerobic: Mobiluncus spp, Clostridium perfringens.
Novapim ikuwonetsa kukhudzana ndi gramu-gramu komanso gram-hasi tizilombo.
Pharmacokinetics
Pambuyo pakukonzekera, mankhwalawa amagawidwa kwathunthu mthupi. Kuzunzika kwa plasma kumadalira msinkhu komanso vuto la wodwala. Achire ndende ya cefepime pambuyo jekeseni imodzi amawonedwa mu ndulu, mkodzo, katulutsidwe opangidwa ndi bronchi, mu zofewa zimakhala za prostate gland ndi appendicitis. Kuchulukitsa kwa maantibayotiki kuma protein a plasma kuli mpaka 19%.
Nthawi yofunikira hafu ya moyo ndi pafupifupi maora awiri, ngakhale atamwa. Kuchotsa mthupi kumachitika ndi kusefa kwa impso, pafupifupi 85% ya kuphwanya kadzulu imatuluka m'thupi ndi mkodzo.
Zizindikiro zogwiritsidwa ntchito
Amawerengera mankhwala ovuta pazotsatira zamankhwala:
- matenda opatsirana a m'munsi ziwalo zamkati kupuma;
- bronchitis;
- chibayo;
- matenda a kwamkodzo thirakiti;
- kuwonongeka kwa impso, kakulidwe ka pyelonephritis;
- kuwonongeka kwa khungu ndi mabakiteriya;
- matenda ofewa a minofu;
- matenda amkati mwa m'mimba mtundu, kuphatikizapo milandu ya peritonitis ndi matenda amisempha;
- febrile neutropenia;
- septicemia - malowedwe a matenda kulowa m'magazi.
Amagwiritsidwanso ntchito pochiza odwala omwe ali ndi vuto la neutropenic ndi chifukwa chosadziwika bwino cha matendawa.
Zisonyezero zakugwiritsa ntchito maantibayotiki m'matumbo a ana ndi awa: chibayo, pyelonephritis, bacterious meningitis.
Contraindication
Ndi zoletsedwa kumwa mankhwala kwa anthu omwe ali ndi vuto lofanana ndi mankhwala ena amtundu wa cephalosporins antibacterial.
Ndi chisamaliro
Malangizo ogwiritsa ntchito amachenjeza za wachibale yemwe waphwanya lamulo la kugwiritsa ntchito mankhwala othandizira - matenda am'mimba. Kusamala kwambiri ndikofunikira mukamagwiritsa ntchito mankhwalawa ndi anthu omwe ali ndi colitis, mosasamala mtundu wake. Pankhaniyi, kumwa maantibayotiki ndikololedwa pokhapokha zotsatira zabwino za kugwiritsidwa ntchito kwake kupitirira zoopsa zopezeka zovuta.
Kodi mutenge bwanji Novapim?
Ma jakisoni a antibiotic amapatsidwa intramuscularly kapena kudzera m'mitsempha. Mlingo ndi kayendetsedwe ka kayendetsedwe kamakonzedwa payokha.
Mlingo wovomerezeka kwa odwala akuluakulu:
- matenda a genitourinary dongosolo, ngakhale kuopsa: 500 mg 1 g, jekeseni intramuscularly kapena mtsempha uliwonse maola 12;
- matenda a pakhungu: 2 g kudzera m'mitsempha ndi maola 12;
- zofewa minofu matenda: 2 g kudzera m`mitsempha kawiri pa tsiku;
- chibayo: 1 mpaka 2 g kudzera mu maola 12 aliwonse;
- matenda amkati pamimba: 2 g kudzera m'mitsempha;
- mankhwalawa febrile neutropenia: 2 ga mtsempha wamagazi maola 8 aliwonse.
Ma jakisoni a antibiotic amapatsidwa intramuscularly kapena kudzera m'mitsempha.
Kugwiritsa ntchito Novapim ngati prophylactic popewa matenda pambuyo pa kuchitira opareshoni: 1 ora musanachite opareshoni, yambitsani 2 g ya mankhwalawa, kenako yankho la Metronidazole (500 mg).
Ndi matenda ashuga
Mlingo wodziwikiratu umatengera payekha malinga ndi kuuma kwa matenda azachipatala kapena malinga ndi ma regimens othandizira.
Zotsatira zoyipa za Novapima
Kuphwanya Mlingo kapena malamulo oyendetsera zimayambitsa zosakhudza:
- Matenda owonongeka: Zizindikiro zowonjezera za hypersensitivity. Pafupipafupi - anaphylaxis, kukula kwa mantha a angioedema.
- M`mimba thirakiti: nseru ndi kusanza, kukula kwa candidiasis a mucous nembanemba zamkati zam'mimba, kutsegula m'mimba. Pafupipafupi - mawonekedwe a pseudomembranous colitis, kudzimbidwa, kupotoza kwa malingaliro a kukoma.
- Pakati mantha dongosolo: mutu ndi chizungulire, kusowa tulo, kusintha kwa chikumbumtima. Pafupipafupi - kukula kwa encephalopathy, kukomoka. Osowa kwambiri - mawonekedwe a kuyerekezera zinthu m'maso, chikomokere, stupor.
- Matenda: Kukula kwa superinfection, vaginitis, vagidi candidiasis.
- Mtima ndi mtima dongosolo: mawonekedwe a tachycardia, kupweteka kwa minofu ya mtima, zotumphukira edema.
- Dongosolo la Lymphatic: thrombocytopenia, magazi m'thupi, osakhalitsa mtundu leukopenia, eosinophilia.
- Njira yodzikonzera: chifuwa chowuma, kufupika, kupweteka pakhosi pakumeza.
- Ziwalo zoberekera: kawirikawiri - kukhazikika kwa aimpso.
Zizindikiro zina zoyipa zomwe zimatha kumachitika mutatenga Novapim: hemolytic mtundu anemia, chiwindi ntchito, mawonekedwe a cholestasis, nephropathy yoopsa.
Zokhudza mphamvu pakuwongolera njira
Zimatha kubweretsa kuwonjezeka kwa kuchuluka kwa mitundu ya psychomotor mtundu, pazomwe zimalimbikitsidwa kuti musamayendetse galimoto ndikugwira ntchito ndi zovuta kupanga.
Malangizo apadera
Mutha kungolowetsa yatsopano yothetsera jakisoni. Mankhwalawa amagwiritsidwa ntchito mosamala kuphatikiza mankhwala ena a antibacterial, chifukwa cha chiwopsezo chachikulu chotenga zizindikiro za hypersensitivity.
Kuchuluka kwa ma antibayotiki m'magazi am'magazi mwa amuna omwe ali ndi makonzedwe amodzi kumakhala kwakukulu kuposa mwa azimayi.
Pambuyo hemodialysis kwa maola atatu, oposa 68% ya mlingo wovomerezeka wa mankhwalawa amachotsedwa m'thupi, motero, mobwerezabwereza makonzedwe a mankhwala atagwiritsidwa ntchito gawo lililonse.
Kutalika kwa mankhwalawa kuyambira masiku 7 mpaka 10. Ndi matenda oopsa omwe ali ndi chithunzi cholimba, njira ya chithandizoyo imatha kutalikitsa.
Ndi jakisoni wambiri wa mankhwala othandizira, tikulimbikitsidwa kusinthasintha malo a jekeseni kuti tisawoneke kupweteka kwa minofu ndi kutupa.
Gwiritsani ntchito mu ukalamba
Odwala omwe ali m'gulu la zaka 65, ngati palibe zopatuka pakugwira ntchito kwa impso, palibe chifukwa chosinthira.
Kupatsa ana
Kuwunikira nthawi zonse zaumoyo wa ana omwe ali ndi thupi lochepera 40 makilogalamu omwe amapatsidwa mankhwala awa amafunikira. Pa matenda a impso kapena chiwindi, pafupifupi mlingo woyenera uyenera kuchepetsedwa.
Mgulu la zaka kuyambira 1 mpaka miyezi iwiri, mankhwala opha mabakiteriya amapatsidwa malinga ndi malangizo apadera. Mlingo ndi 30 mg pa kilogalamu ya thupi, kutumikiridwa maola aliwonse 8 kapena 12, kutengera mphamvu ya matenda opatsirana. Mlingo wa ana olemera kuyambira 40 makilogalamu ndi 100 mg pa kilogalamu ya kulemera kwa tsiku (50 mg maola 8-12 aliwonse).
Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere
Palibe chidziwitso chokhudza chitetezo cha mankhwala osokoneza bongo mwa amayi apakati komanso munthawi yoyambira. Popeza kuopsa kwa zotsatira zoyipa za mwana wosabadwa, mankhwala sanapatsidwe mankhwala.
Ndi mankhwala okhawo omwe angapereke njira yothandizira achire, kuyamwa kuyenera kusokonezedwa kwa nthawi yayitali.
The ntchito aimpso kuwonongeka
Odwala omwe akupatuka kuntchito ya impso, ngati chilolezo cha creatine chafika mpaka 30 ml pamphindi, mlingo woyenera wa mankhwalawa umayenera kuchepetsedwa.
Gwiritsani ntchito ntchito yolakwika ya chiwindi
Mlingo woyenera umachepetsedwa.
Mankhwala ochulukirapo a Novapim
Imadziwonekera yokha mu kuwonjezeka kwa kukula kwa zizindikiro zammbali. Mankhwala osokoneza bongo ndi chizindikiro. Ndi chitukuko cha anaphylactic, makonzedwe a adrenaline amafunikira nthawi yomweyo. Pa mlingo waukulu wa mankhwalawo m'magazi (kuti athetse msanga m'thupi), peritoneal dialysis imafunika.
Kuchita ndi mankhwala ena
Njira yolimbana ndi antibacterial yokhala ndi zoterezi: 0.9% sodium chloride, 10% shuga, yankho la Ringer.
Sitikulimbikitsidwa kuti izitengedwa nthawi yomweyo ndi Gentamicin Sulfate, Vancomycin, Metronidazole.
Kugwiritsa ntchito munthawi yomweyo kwa Novapim ndi aminoglycosides ndi okodzetsa sikuphatikizidwa. Kuphatikiza uku kumabweretsa kukula kwa nephrotic.
Kuyenderana ndi mowa
Mowa komanso zakumwa zoledzeretsa zili zoletsedwa makamaka pamankhwala othandizira.
Analogi
Mankhwala omwe ali ndi mawonekedwe ofanana: Abipim, Maxicef, Piccef, Focepim, Cefuroxime, Cefi.
Kupita kwina mankhwala
Kodi ndingagule popanda kulandira mankhwala?
Sizogulitsidwa popanda fomu yodalirika.
Mtengo wa Novapim
Mtengo wa mankhwalawa umachokera ku ruble 75.
Zosungidwa zamankhwala
Pamatenthedwe mpaka + 25 ° ะก.
Tsiku lotha ntchito
Zaka zitatu
Wopanga
Lupine Limited, India.
Ndemanga za Novapima
Marina, wazaka 35, Vorkuta: "Awa ndi mankhwala omwe amachotsa matendawa mosavuta. Koma ali ndi vuto lalikulu - jakisoni ndiwowawa kwambiri. Mutha kupaka jekeseni wa Lidocaine. Komabe, ichi ndi chida chothandiza, komanso pamtengo wotsika."
Ksenia, wazaka 41, Perm: "Jakisoni wa Novapim adauzidwa ndi dotolo kuti azichiritsa zithupsa kumaso ndi thupi, chifukwa ndidavutika kwa zaka zambiri, koma sizinathandize. Mankhwala opha maantibayotiki adatenga masiku 10, jakisoni anali opweteka, koma adalekerera ndi Lidocaine. Zaka 1.5 atalandira chithandizo, koma pakadali pano palibe zithupsa zomwe zidawoneka. "
Eugene, wazaka 38, Dnipro: "Mchimwene wanga adatenga mankhwalawa kuchitira matenda ofooketsa ngati chinzonono. Chilichonse chapita patatha sabata limodzi, masiku enanso atatu amapaka jakisoni woletsa kuthetsa matenda. Nthawi zina mutu umandisokoneza. Ngakhale izi, maantibayotiki ndi abwino, angakwanitse komanso amathandiza msanga. "