Insulin Lantus Solostar: malangizo ndi kuwunika

Zotsatira za pharmacological

Chithandizo cha Lantus ndi insulin glargine. Amapezeka ndi majini obwezeretsanso pogwiritsa ntchito mtundu wa k-12 wa bakiteriya Escherichia coli. M'malo osaloŵerera, samasungunuka pang'ono, mu acid acid sing'anga imasungunuka ndikupanga microprecipitate, yomwe imatulutsa insulini pang'onopang'ono. Chifukwa cha izi, Lantus ali ndi mbiri yosavuta kuchitira mpaka maola 24.

Kupanga kwakukulu pa pharmacological:

• Ochepa adsorption ndi mbiri yopanda kanthu mkati maola 24.
• Kuponderezedwa kwa proteinolysis ndi lipolysis mu adipocytes.
• Gawo lolimbikira limamangirira ma insulin receptors maulendo 5-8 mwamphamvu.
• Kukuwongolera kagayidwe kachakudya kagayidwe kachakudya, kuletsa shuga kupangika kwa chiwindi.

Kupanga

Mu 1 ml ya Lantus Solostar muli:

• 3.6378 mg wa insulin glargine (yochokera 100 IU ya insulin ya anthu);
• 85% glycerol;
• madzi a jakisoni;
• hydrochloric moyikirapo asidi;
• m-cresol ndi sodium hydroxide.

Kutulutsa Fomu

Lantus - yankho lomveka bwino la jakisoni wa sc, likupezeka mu:

• makatoni azida a OptiClick system (5pcs pa paketi iliyonse);
• Syringe zolembera Lantus Solostar;
• Syringe cholembera ya OptiSet mu phukusi limodzi 5 ma PC. (gawo 2);
• Mbale 10 ml (magawo 1000 pa botolo).

Zizindikiro zogwiritsidwa ntchito

1. Akuluakulu ndi ana ochokera zaka 2 zokhala ndi matenda amtundu wa 1.
2. Type 2 shuga mellitus (pankhani ya kusakwaniritsidwa kwa mapiritsi akukonzekera).

Kuchita ndi mankhwala ena

Pali mankhwala omwe amakhudza kagayidwe kazakudya, pomwe akuwonjezera kapena kuchepetsa kufunika kwa insulin.

Chepetsa shuga: pakamwa antidiabetesic othandizira, sulfonamides, ACE zoletsa, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.

Onjezani shuga: mahomoni a chithokomiro, diuretics, sympathomimetics, kulera kwapakamwa, zotumphukira za phenothiazine, proteinase inhibitors.

Zinthu zina zimakhala ndi mphamvu ya hypoglycemic komanso hyperglycemic. Izi zikuphatikiza:

• beta blockers ndi mchere wa lithiamu;
• mowa
• clonidine (antihypertensive mankhwala).

Contraindication

1. Ndi zoletsedwa kugwiritsa ntchito mwa odwala omwe ali ndi vuto la insulin glargine kapena othandizira.
2. Hypoglycemia.
3. Chithandizo cha matenda ashuga ketoacidosis.
4. Ana osakwana zaka 2.

Zotheka zimachitika kawirikawiri, malangizo akuti mwina atha:

• lipoatrophy kapena lipohypertrophy;
• thupi lawo siligwirizana (edema ya Quincke, kugwedezeka kwa matumbo, bronchospasm);
• kupweteka kwa minofu ndi kuchedwa mu thupi la ayodini;
• dysgeusia ndi kuwonongeka kwa mawonekedwe.

Kusintha kupita ku Lantus kuchokera ku insulin ina

Ngati munthu wodwala matenda ashuga agwiritsa ntchito ma insulin apakatikati, ndiye kuti musinthana ndi Lantus, mulingo ndi mankhwalawa amasinthidwa. Kusintha kwa insulin kuyenera kuchitika kokha kuchipatala.

Ngati NPH insulins (Protafan NM, Humulin, etc.) anali kutumikiridwa 2 pa tsiku, ndiye kuti Lantus Solostar amagwiritsidwa ntchito nthawi imodzi. Nthawi yomweyo, kuti muchepetse chiopsezo cha hypoglycemia, mlingo woyambirira wa insulin glargine uyenera kukhala wocheperako ndi 30% poyerekeza ndi NPH.

M'tsogolomu, dokotala amayang'ana shuga, njira yodwala, kulemera ndi kusintha kuchuluka kwa mayendedwe omwe amaperekedwa. Pakatha miyezi itatu, kugwiritsa ntchito bwino kwa mankhwalawa kungayang'anitsidwe ndikusanthula kwa glycated hemoglobin.

Malangizo pavidiyo:

Analogi

Ku Russia, onse odwala matenda a shuga omwe amadalira insulin anasamutsidwa kuchoka ku Lantus kupita ku Tujeo. Malinga ndi kafukufuku, mankhwalawa ali ndi chiopsezo chochepa cha kukhala ndi hypoglycemia, koma machitidwe, anthu ambiri amadandaula kuti atasinthira ku Tujeo shuga awo alumpha kwambiri, motero amakakamizidwa kugula okha Lantus Solostar insulin.

Levemir ndi mankhwala abwino kwambiri, koma ali ndi chinthu china chogwira ntchito, ngakhale nthawi yayitali ndi maola 24.

Aylar sanakumane ndi insulin, malangizowo akunena kuti ndi Lantus yemweyo, koma wopanganso ndi wotsika mtengo.

Insulin Lantus pa nthawi yapakati

Maphunziro a zachipatala a Lantus omwe ali ndi amayi apakati sanachitike. Malinga ndi zomwe sizinagwiritsidwe ntchito, mankhwalawa samakhudza kwambiri mayendedwe a mwana komanso mayiyo.

Kuyesera kunachitika pa zinyama, pomwepo zimatsimikiziridwa kuti insulin glargine ilibe vuto la kubereka.

Lantus Solostar woyembekezera atha kupatsidwa mankhwala a insulin NPH. Amayi amtsogolo akuyenera kuwunika shuga wawo, chifukwa mu trimester yoyamba, kufunika kwa insulin kumatha kuchepa, komanso mu trimester yachiwiri ndi yachitatu.

Osawopa kuyamwitsa mwana; malangizo ake alibe zomwe Lantus imatha kupita mkaka wa m'mawere.

Momwe mungasungire

Tsiku lotha ntchito ya Lantus ndi zaka 3. Muyenera kusungira m'malo amdima otetezedwa ndi kuwala kwa dzuwa pa kutentha kwa madigiri 2 mpaka 8. Nthawi zambiri malo abwino kwambiri ndi firiji. Poterepa, onetsetsani kuti mwayang'ana kutentha, chifukwa kuzizira kwa insulin Lantus koletsedwa!

Kuyambira koyamba kugwiritsa ntchito, mankhwalawa amatha kusungidwa kwa mwezi umodzi m'malo opanda khungu kutentha osaposa 25 digiri (osati mufiriji). Osagwiritsa ntchito insulin yomwe yatha.

Poti mugule, mtengo

Lantus Solostar amalembedwa mwaulere ndi mankhwala ndi endocrinologist. Komanso zimachitika kuti wodwala matenda ashuga ayenera kugula yekha mankhwala ku pharmacy. Mtengo wamba wa insulin ndi ma ruble 3300. Ku Ukraine, Lantus angagulidwe 1200 UAH.

Ndemanga

Odwala matenda ashuga akuti ndi insulin yabwino kwambiri, kuti shuga yawo imasungidwa mwa malire. Nazi zomwe anthu akunena za Lantus:

Ambiri adangotsala ndemanga zabwino zokha. Anthu angapo adanena kuti Levemir kapena Tresiba ndiwofunikira.