Kuwunikira kwa mankhwala a statin kuti muchepetse cholesterol

Cholesterol okwera amachititsa matenda amtima.

Kuti muchepetse kuyamwa kwake, mankhwala angapo amagwiritsidwa ntchito, makamaka, mankhwala a statin. Amasinthasintha kagayidwe ka lipid ndikukhala bwino.

Chifukwa chiyani cholesterol ikukwera?

Cholesterol ndi gulu lachilengedwe lomwe limapezeka m'thupi ndipo limagwira ntchito yake. Ndi gawo lofunikira la lipid metabolism.

Kuzindikira kwa zinthu kumatha kupitilira muyeso womwe unakhazikitsidwa. Izi zimasokoneza thanzi ndipo zimayambitsa matenda angapo. Izi zimaphatikizapo kugunda kwa mtima ndi stroko, angina pectoris, atherosulinosis.

20% ya cholesterol yakunja imachokera ku chakudya, 80% yotsalayo imapangidwa ndi thupi. Pophwanya lamulo la kudya ndi kutulutsa chinthu, zinthu zake zimasintha.

Zomwe zimayambitsa mkati ndi kunja zimathanso kukweza mafuta m'thupi:

• kagayidwe kachakudya matenda;
• kubadwa mwabadwa;
• kudya kwambiri zodzaza ndi mafuta a nyama;
• kugwiritsa ntchito mankhwala ena;
• matenda oopsa
• kupsinjika kwa nthawi yayitali;
• matenda a shuga;
• kusowa zolimbitsa thupi;
• kusasamala kwa mahomoni kapena kubwezeretsanso;
• kunenepa kwambiri komanso kunenepa kwambiri;
• ukalamba.

Zisonyezo zakusanthula kwa labotale ndi:

• kuzindikira kwa atherosulinosis ndi kupewa kwake pakakhala pachiwopsezo;
• kukhalapo kwa mitundu ina yamtima;
• matenda a impso;
• matenda a endocrine - hypothyroidism;
• matenda ashuga
• matenda a chiwindi.

Ngati zovuta zapezeka, dokotala amakupatsani njira zingapo zochepetsera cholesterol. Mankhwala a Statin amatha kuperekedwa malinga ndi chithunzi cha chipatala.

Kodi ma statins ndi ati?

Ili ndi gulu la mankhwala ochepetsa lipid omwe amapangidwira kuti muchepetse cholesterol yoyipa. Amaletsa ntchito ya chiwindi, yomwe imakhudzidwa ndikupanga zinthu.

Matenda amatengedwa ngati mankhwala othandizira kupewa matenda oyamba ndi obwereza pamtima. Gulu la mankhwala limasinthasintha magawo amitsempha yamagazi ndikuletsa mapangidwewo.

Ndi mankhwala okhazikika, odwala amatha kutsitsa cholesterol ndi 40%. Malinga ndi ziwerengero, amachepetsa kufa kwa matenda a mtima ndi pafupifupi kawiri.

Mankhwalawa ali ndi cholesterol yotsitsa, amachepetsa kaphatikizidwe ka lipoproteins ndi chiwindi, amasinthasintha magazi, achulukitsa mamasukidwe ake, amalimbikitsa kuchuluka kwa mitsempha yamagazi, kumasuka ndikukula, ndikulepheretsa mapangidwe a zipupa pamakoma.

Kutenga nthawi yayitali bwanji? Mankhwalawa amachita pokhapokha atalandira, atatsiriza, zizindikilo zimatha kubwerera ku ziwerengero zam'mbuyomu. Kugwiritsira ntchito kosatha sikuchotsedwa.

Zizindikiro zogwiritsidwa ntchito

Zisonyezero zakugwiritsa ntchito ma statins kutsitsa cholesterol:

• hypercholesterolemia;
• kwambiri atherosclerosis ndi kuopsa kwa chitukuko chake;
• kupewa kwakukulu kwa stroko, mtima;
• kukonza mankhwala pambuyo sitiroko, mtima;
• ukalamba (kutengera kusanthula deta);
• angina pectoris;
• Matenda a mtima a Ischemic;
• chiopsezo chotchinga mitsempha;
• homozygous cholowa (banja) hypercholesterolemia;
• kuchitapo kanthu kwa mtima ndi mtsempha wamagazi.

Mwa zina zotsutsana ndi ma statins:

• kukanika kwa impso;
• tsankho kwa zigawo zikuluzikulu;
• mimba
• kuyamwitsa
• Hypersensitivity zimachitikira;
• wazaka 18.

Mndandanda wa mankhwala a statin

Mankhwala a Statin amayimilidwa ndi mibadwo 4.

Mwa chilichonse mwa izo muli zinthu zomwe zimayikidwa ndi nthawi ya kukhazikitsidwa:

1. M'badwo woyamba - Lovastatin, Simvastatin, Pravastatin. Zoyambira ndi zachilengedwe. Ntchito yochepetsa cholesterol ndi 25%. Ndiwosagwira pamtengo wotsika ndipo amatha kuwonetsa zovuta zake. M'badwowo ukuyimiriridwa ndi mankhwala otsatirawa: Vasilip - 150 r, Zokor - 37 r, Lovastatin - 195 r, Lipostat - 540 r.
2. Mbadwo wachiwiri ndi fluvastatin. Chiyambacho ndi chosakanikirana. Ntchito yochepetsa zizindikiro ndi 30%. kuchitapo kanthu kwakutali komanso kuchuluka kwa zisonyezero kuposa otsogola. Mayina a mankhwala am'badwo wa 2: Leskol ndi Leskol Forte. Mtengo wawo ndi pafupifupi 865 p.
3. Mbadwo wachitatu ndi Atorvastatin. Chiyambi chake ndichopangidwa. Ntchito yochepetsera kugwiritsidwa ntchito kwa zinthuzo mpaka kufika pa 45%. Chepetsani msanga LDL, TG, onjezani HDL. Gulu la mankhwalawa limaphatikizapo: Atokor - rubles 130, Atorvasterol - 280 p, Atoris - 330 p, Limistin - 233 p, Liprimar - 927 p, Torvakard - 250 p, Tulip - 740 p, Atorvastatin - 127 p.
4. Mbadwo wachinayi ndi Rosuvastatin, Pitavastatin. Chiyambi chake ndichopangidwa. Ntchito yochepetsa cholesterol ili pafupifupi 55%. M'badwo wokalamba kwambiri, wofanana mu kuchitapo chachitatu. Sonyezani njira zochizira pamunsi. Kuphatikizidwa ndi mankhwala ena a mtima. Otetezeka komanso wogwira mtima kuposa mibadwo yakale. Gulu la 4th la mankhwala limaphatikizapo: Rosulip - 280 r, Rovamed - 180 r. Tevastor - 770 p, Rosusta - 343 p, Rosart - 250 p, Mertenil - 250 p, Crestor - 425 p.

Zokhudza thupi

Mankhwala a Statin amathandiza odwala omwe ali ndi matenda amtima. Amachepetsa kutupa m'matumbo, cholesterol, komanso amachepetsa kuopsa kwa matenda a mtima ndi stroko. Mankhwala amathandizanso kuyambitsa mavuto ambiri kuchokera kwaofatsa mpaka kwambiri.

Popeza mapiritsi amatengedwa kwa nthawi yayitali, chiwindi chimakhala pachiwopsezo. Mothandizidwa ndi mankhwalawa, kangapo pachaka, kuphatikiza magazi kumachitika.

Zotsatira zoyipa za mankhwala zimaphatikizapo:

• khungu lawo siligwirizana;
• kupweteka mutu komanso chizungulire;
• kufooka kowonjezereka ndi kutopa;
• matenda am'mimba;
• zotumphukira neuropathy;
• hepatitis;
• utachepa libido, kusabala;
• kupweteka pamimba;
• zotumphukira edema;
• chisamaliro chododometsa, kuiwala kukumbukira kwamitundu yosiyanasiyana;
• thrombocytopenia;
• kufooka kwa minofu ndi kukokana;
• mavuto a chiwindi
• myopathy
• osakhalitsa padziko lonse lapansi amnesia - kawirikawiri;
• rhabdomyolysis sichisowa.

Ndi mankhwala ati oti musankhe?

Statin ndi gulu lamankhwala amphamvu. Sangapangidwe kuti azidzipiritsa nokha. Amangolembedwa ndi adokotala okha, poganizira zovuta za matendawa ndi zotsatira za kafukufuku. Zimatengera kuopsa konse komwe kumachitika chifukwa cha ukalamba, matenda opatsirana, kumwa mankhwala ena.

Pakupita miyezi isanu ndi umodzi, kuwunika kwa biochemical kumachitika mwezi uliwonse kuwunika ntchito ya chiwindi. Maphunziro ena amapitilira katatu pachaka.

Kodi mankhwalawa amasankhidwa bwanji? Dokotala amasankha mankhwalawo ndikupereka maphunzirowo. Mukamaliza, zizindikiro zimayang'aniridwa. Palibe mphamvu, ndi osakwanira Mlingo, kuwonetsedwa kwa zoyipa, wina mankhwala. Atatenga mankhwala ofunikira, chiwembucho chakhazikika.

Zotsatira zoyipa, kuphatikiza ndi mankhwala ena, nthawi yoyendetsedwa imayang'aniridwa. Ziwerengero za m'badwo wotsiriza zimadziwika kuti ndizabwino kwambiri. Amawonetsa kuyendetsa bwino chitetezo ndikuchita.

Pafupifupi palibe vuto ndi kagayidwe ka glucose, pitani bwino ndi mankhwala ena a mtima. Pochepetsa mankhwalawa (ndi zotsatira zake), zoopsa zomwe zimapangitsa kukhala ndi mavuto zimachepa.

Nkhani ya kanema yochokera kwa Dr. Malysheva wonena za ma statins:

Pindulani ndi kuvulaza

Kutenga ma statins kuli ndi mfundo zingapo zosalimbikitsa.

Mapindu ake ndi monga:

• kupewa sitiroko;
• kupewa matenda a mtima;
• Kuchepetsa 50% ya kufa kuchokera ku mtima;
• mankhwalawa atherosulinosis;
• pafupifupi 50% kuchepetsa cholesterol;
• Kuchotsa kutupa;
• kusintha kwa mtima.

Zina zoyipa zakuchiritsa ndizothandiza:

• kuchita pokhapokha kuvomera;
• Yaitali, mwina yogwiritsa ntchito mpaka kalekale;
• kusokoneza chiwindi;
• mavuto ambiri;
• kukopa zochitika m'maganizo.

Zogulitsa zina zimakhala ngati ma chilengedwe:

• zipatso ndi ndiwo zamasamba zomwe zimakhala ndi vitamini C - rose rose, currants, zipatso za malalanje, tsabola wokoma;
• zonunkhira - turmeric;
• njere, masamba, zipatso zokhala ndi pectin - zipatso za malalanje, maapulo, kaloti;
• zopangidwa ndi nikotini acid - nyama, mtedza, nsomba zofiira;
• malonda omwe ali ndi Omega-3 - mafuta a masamba, nsomba zofiira.

Chisamaliro chachikulu chimalipidwa kuphatikizidwa ndi mankhwala ena. Mafuta amapangira katundu pachiwindi. Simalimbikitsidwa kuphatikizidwa ndi mowa komanso maantibayotiki, Cyclosporin, Verapamil, nicotinic acid.

Gwiritsani ntchito mosamala ndi ma fiber. Kutenga iwhypertensive, othandizira a hypoglycemic pamodzi ndi ma statins angakulitse chiopsezo chotenga myopathy.

Kanema pamankhwala a cholesterol - kuvomereza kapena ayi?

Malingaliro odwala

Ndemanga za odwala zimawonetsa kukhalapo kwa mfundo zabwino komanso zoyipa pochizira ma statins. Ambiri amati polimbana ndi cholesterol yayikulu, mankhwala amawonetsa zotsatira zowoneka. Zotsatira zoyipa zambiri zidadziwikanso.

Ndemanga za madotolo za ma statins ndi osakanikirana. Ena amati ndi othandiza komanso kupitilira kwawo, pomwe ena amati ndi zoyenera.

Anandipatsa Atoris kuti ndichepetse cholesterol. Mutatha kumwa mankhwalawa, chizindikirocho chatsika kuchoka pa 7.2 mpaka 4.3. Chilichonse chinkawoneka ngati chikuyenda bwino, kenako kutupikira mwadzidzidzi kunatulukira, kuphatikizana ndi ululu wamminyewa ndi minofu. Tolerate sanakhale woleza. Chithandizo chake chidayimitsidwa. Patatha milungu iwiri, zonse zidapita. Ndipita kukakumana ndi adotolo, mumulole kuti akupatseni mankhwala ena.

Olga Petrovna, wa zaka 66, Khabarovsk

Abambo anga adasankhidwa kukhala Crestor. Ndi m'badwo wotsiriza wama statins, wabwinobwino kwambiri kuposa onse. Pambuyo pake panali Leskol, panali zowonjezereka. Bambo akhala akumwa Krestor pafupifupi zaka ziwiri. Zimawonetsa zotsatira zabwino, ndipo mbiri ya lipid imakumana ndi miyezo yonse. Nthawi zina pamakhala chimbudzi chokha. Dokotala wopezekayo akuti zotsatira zake zimakhala zabwino kwambiri kuposa momwe amayembekezera. Pofuna kupulumutsa ndalama, sitikufuna kusinthitsa ndalama zotsika mtengo.

Oksana Petrova, wazaka 37, St. Petersburg

Apongoziwo akhala akutenga zaka 5 pambuyo pogwidwa kwambiri. Nthawi zingapo anasintha mankhwalawa. Wina sanatsike cholesterol, winayo sanakwanitse. Pambuyo posankha mosamala, tinaima ku Akorta. Mwa mankhwala onse, adapezeka kuti ali oyenera kwambiri ndi zotsatira zoyipa zochepa. Apongozi awo nthawi zonse amawunika momwe chiwindi chimakhalira. Mayeserowa samakhala nthawi zonse. Koma kwa iye, palibe chosankha.

Alevtina Agafonova, wazaka 42, Smolensk

Dotolo adandiuza Rosuvastatin kwa ine - adati m'badwo uno ndiwo wabwino koposa, wokhala ndi zovuta zochepa. Ndinawerenga malangizo oti agwiritse ntchito, komanso kuchita mantha pang'ono. Pali ma contraindication ambiri ndi zotsatira zoyipa kuposa mawonekedwe ndi mapindu. Zikhala kuti timachitira imodzi, ndi kulumala inayo. Ndinayamba kumwa mankhwalawo, ndimamwa kwa mwezi wathunthu, mpaka pano osapitirira muyeso.

Valentin Semenovich, wazaka 60, Ulyanovsk

Ma Statin ndi ofunika kwambiri mu atherosulinosis, kugunda kwa mtima, komanso stroko. Tsoka ilo, nthawi zina munthu sangathe popanda iwo. Mankhwala sangathetse vuto lathunthu poletsa zovuta. Koma zinthu zina zikuyenda bwino.

Agapova L.L., katswiri wamtima

Statin ndi gulu la mankhwala omwe ali pamndandanda wa mankhwala ofunikira polimbana ndi cholesterolemia ndi zotsatira zake. Ndi chithandizo chawo, ndizotheka kuchepetsa anthu omwe akuvutika ndi mikwingwirima ndi matenda a mtima. Mbadwo wachinayi umawonedwa ngati wothandiza kwambiri komanso wotetezeka.