Metformin ndi Diabeteson: mapindu ndi zovulaza ndi kusiyana pakati pa mankhwala

Odwala ambiri omwe ali ndi matenda ashuga ali ndi chidwi ndi funso: Metformin kapena Diabeteson - ndibwino?

Mankhwalawa onse amapangidwa kuti achepetse shuga m'magulu 2 a shuga.

Chaka chilichonse kuchuluka kwa anthu omwe akudwala matendawa kumawonjezeka, motero pakufunika kusankha mankhwala othandiza kuchepetsa shuga. Kukhala wotchuka pakati pa mankhwala ambiri a hypoglycemic, iliyonse ili ndi zabwino komanso zovuta zake.

Zomwe mungagwiritse ntchito Metformin

Metformin ndi mankhwala odziwika bwino a antidiabetes omwe amagwiritsidwa ntchito padziko lonse lapansi. Sizosadabwitsa kuti gawo lalikulu la metformin - hydrochloride limagwiritsidwa ntchito mu mankhwala ambiri ofanana.

Zisonyezo zogwiritsira ntchito mankhwalawa ndi shuga (2) popanda chizolowezi cha ketoacidosis, komanso kuphatikiza ndi insulin.

Uku ndikusiyana kwakukulu pakati pa Metformin, popeza Diabeteson sagwiritsidwa ntchito ndi jakisoni wa mahomoni.

Kugwiritsa ntchito mankhwalawa kungakhale koletsedwa ngati:

• Hypersensitivity zigawo zikuluzikulu za mankhwala;
• kunyamula mwana ndi kuyamwitsa;
• kudya zosakwana 1000 kcal / tsiku;
• matenda a shuga ndi chikomokere, ketoacidosis;
• zikhalidwe za hypoxia ndi madzi osowa madzi m'thupi;
• matenda pachimake ndi matenda;
• matenda opatsirana;
• opaleshoni kuchitapo kanthu;
• kukanika kwa chiwindi;
• lactic acidosis;
• poyizoni woledzera;
• Maphunziro a X-ray ndi radioisotope ndikuyambitsa zinthu zokhala ndi ayodini.

Momwe mungamwe mankhwalawo molondola komanso kuchuluka kwake? Katswiri wokhazikika yekha ndi amene angadziwe kuchuluka kwa mankhwalawo, poganizira kuchuluka kwa glycemia komanso kuchuluka kwa wodwala. Mlingo woyamba wapakati umasiyana kuchokera 500 mpaka 1000 mg patsiku.

Njira ya mankhwalawa imatha mpaka milungu iwiri, pambuyo pake dokotala amawasintha mankhwalawa kutengera mphamvu ya mankhwalawa. Ngakhale ndikukhalabe ndi shuga wambiri, ndikofunikira kumwa mpaka 2000 mg patsiku. Mlingo wapamwamba tsiku lililonse ndi 3000 mg. Odwala okalamba (opitilira zaka 60) ayenera kudya mpaka 1000 mg patsiku.

Chifukwa chogwiritsa ntchito molakwika kapena pazifukwa zina, mawonekedwe a zovuta zoyipa amatha:

1. Hypoglycemic state.
2. Megablastic anemia.
3. Zotupa za pakhungu.
4. Mavuto a vitamini B12.
5. Lactic acidosis.

Nthawi zambiri, masabata awiri oyamba, odwala ambiri amakhala ndi kudzimbidwa. Kungakhale kusanza, kutsekula m'mimba, mpweya wowonjezereka, kulawa kwazitsulo kapena kupweteka kwam'mimba. Kuti muchotse zizindikiro zotere, wodwalayo amatenga antispasmodics, zotumphukira za atropine ndi ma antacid.

Ndi mankhwala osokoneza bongo, lactic acidosis imayamba. Choyipa chachikulu kwambiri, izi zimapangitsa kuti pakhale kudekha komanso kufa. Chifukwa chake, ngati wodwala wakwiya, kuchepa kwa kutentha kwa thupi, kukomoka komanso kupumira mofulumira, ayenera kupita naye kuchipatala mwachangu!

Zina za mankhwala a Diabeteson MV

Mankhwala oyambirirawo amatengedwa ngati Diabetes.

Posachedwa, mankhwalawa agwiritsidwa ntchito pocheperapo, popeza Diabeteson adalowedwa m'malo ndi Diabeteson MV, omwe amatengedwa nthawi 1 yokha patsiku.

Gawo lalikulu la mankhwala a hypoglycemic ndi gliclazide.

Mankhwalawa akuwonetsedwa ngati ali ndi matenda ashuga (2), pomwe chithandizo chamankhwala ndi masewera sizithandiza shuga ochepa.

Mosiyana ndi Metformin, Diabetes imagwiritsidwa ntchito pofuna kupewa kuti muchepetse matenda a nephropathy, retinopathy, stroke, komanso myocardial infarction.

Nthawi zina, kugwiritsa ntchito mankhwala a Diabeteson MV atha kuphatikizidwa kwa odwala chifukwa:

• Hypersensitivity pazomwe zili;
• kunyamula mwana ndi kuyamwitsa;
• kugwiritsa ntchito miconazole mu zovuta;
• shuga wodalira insulin;
• zaka za ana (mpaka zaka 18);
• matenda ashuga, precoma ndi ketoacidosis;
• kwambiri aimpso ndi / kapena kulephera kwa chiwindi.

Kuphatikiza apo, sikulimbikitsidwa kugwiritsa ntchito mankhwalawa limodzi ndi danazol kapena phenylbutazone. Chifukwa chakuti mankhwalawa ali ndi lactose, kugwiritsidwa ntchito kwake ndikosayenera kwa odwala omwe ali ndi vuto la tsankho la glucose / galactose malabsorption kapena galactosemia. Sitilimbikitsidwanso kwambiri kugwiritsa ntchito Diabeteson MV muukalamba (wopitilira zaka 65) ndi:

1. Mtima.
2. Chakudya chopanda malire.
3. Kulephera kwamkati ndi / kapena chiwindi.
4. Ntchito ya chithokomiro yachepa.
5. Matenda osakwanira kapena odabwitsa.
6. Uchidakwa wambiri.
7. Yaitali mankhwala a corticosteroids.

Katswiri wokhawo amene amapita ndi amene amawadziwa kuchuluka kwa mankhwalawo. Malangizowo amalimbikitsa kumwa mankhwalawa m'mawa kamodzi patsiku. Mlingo watsiku ndi tsiku umachokera pa 30 mpaka 120 mg. Kwa odwala azaka zopitilira 65, mlingo woyenera kwambiri ndi 30 mg tsiku lililonse. Mlingo womwewo uyenera kutsatiridwa ndi mwayi waukulu wokhala ndi hypoglycemia. Chifukwa chogwiritsa ntchito molakwika, vuto lomwe lingayambike kwa Diabeteson limawonetsedwa motere:

• kuchepa msanga kwamisempha (chifukwa cha bongo);
• kuchuluka kwa chiwindi michere - ALT, zamchere phosphatase, AST;
• cholestatic jaundice;
• kugaya chakudya
• kuphwanya zida zowoneka;
• chiwindi
• matenda a hematological (leukopenia, kuchepa magazi, granulocytopenia ndi thrombocytopenia);

Kuphatikiza apo, mitundu ingapo ya pakhungu (zotupa, edema ya Quincke, kusintha kwa maonekedwe aukali, kuyabwa).

Kuphatikiza kwa Mankhwala Osokoneza bongo

Nthawi zina kuyanjana kwa mitundu iwiri ya mankhwala nkosatheka.

Chifukwa cha kugwiritsidwa ntchito kwawo, kosasinthika, komanso ngakhale zotsatira zakupha zimatha kuchitika.

Pazifukwa izi, wodwalayo ayenera kuwona dokotala yemwe amawaganizira zinthu zonse zomwe zingakhudze momwe mankhwalawo amathandizira, kaya akhale a Diabetes kapena Metformin.

Pali mankhwala ena omwe angapangitse kuti achepetse ndi kuchepetsa mankhwalawa.

Mankhwala omwe amalimbikitsa zochita za Metformin, momwe shuga amachepera:

1. Zochokera ku sulfonylureas.
2. Jakisoni wa insulin Mwambiri, sikuti nthawi zonse ndikofunikira kuti mupeze insulini mosamala pogwiritsa ntchito mankhwala ochepetsa shuga.
3. Zothandiza pofikira.
4. NSAIDs.
5. β-blockers.
6. Cyclophosphamide.
7. Mao ndi ACE zoletsa.
8. Acarbose.

Mankhwala omwe shuga yanthawi zambiri atatha kutenga diabeteson MV yafupika:

• Miconazole;
• Phenylbutazone;
• Metformin;
• Acarbose;
• Jakisoni wa insulin;
• Thiazolidinediones;
• GPP-1 agonists;
• β-blockers;
• Fluconazole;
• MAO ndi ACE zoletsa;
• Clarithromycin;
• Sulfonamides;
• Mbiriamine H2 receptor blockers;
• NSAIDs
• DPP-4 zoletsa.

Zomwe zimathandizira kuwonjezeka kwa shuga mukamatengedwa ndi Metformin:

1. Danazole
2. Thiazide ndi loop okodzetsa.
3. Chlorpromazine.
4. Ma antipsychotic.
5. GCS.
6. Epinofrin.
7. Zopatsa mphamvu za nicotinic acid.
8. Sympathomimetics.
9. Epinephrine
10. Timadzi a chithokomiro.
11. Glucagon.
12. Kulera (pakamwa).

Mankhwala omwe amachulukitsa hyperglycemia akagwiritsidwa ntchito ndi Diabeteson MV:

• Ethanoli;
• Danazole;
• Chlorpromazine;
• GCS;
• Tetracosactide;
• Beta2-adrenergic agonists.

Metformin, ngati mukumwa mlingo waukulu wa mankhwalawo, imafooketsa zotsatira za anticoagulants. Kugwiritsa ntchito cimetidine ndi mowa kumayambitsa lactic acidosis.

Diabeteson MB imatha kukulitsa mphamvu ya ma anticoagulants m'thupi.

Ndemanga ndi mitengo yamankhwala

Mtengo wa mankhwalawo umathandizanso kwambiri. Posankha mankhwala ofunikira, wodwalayo samangoganizira chithandizo chake, komanso mtengo wake, kutengera luso lawo lazachuma.

Popeza mankhwalawa Metformin ndi otchuka kwambiri, amapangidwa pansi pa malonda ambiri. Mwachitsanzo, mtengo wa Metformin Zentiva umasiyana kuchokera pa ma ruble a 105 mpaka 160 (kutengera mtundu wa zovuta), Metformin Canon - kuchokera ku ruble 115 mpaka 245, Metformin Teva - kuchokera ku 90 mpaka 285 rubles, ndi Metformin Richter - kuchokera ku ma ruble 185 mpaka 245.

Ponena za mankhwala a diabeteson MV, mtengo wake umasiyanasiyana 300 mpaka 330 rubles. Monga mukuwonera, kusiyana kwa mtengo ndikuwonekera kwambiri. Chifukwa chake, wodwala wokhala ndi ndalama zochepa amakhala wokonda kusankha njira yotsika mtengo kwambiri.

Pa intaneti mutha kupeza ndemanga zabwino zambiri za mankhwalawa. Mwachitsanzo, ndemanga ina ya Oksana (wazaka 56): "Ndili ndi matenda ashuga a 2, poyamba sindingachite jakisoni wa insulin, koma pamapeto pake ndinayeneranso kuwalandira. Tsoka ilo, sindinathe kukwanitsa kuchuluka kwa shuga. Kenako ndinasankha kumwa Metformin: Nditamwa mapilitsi ndikulowetsa insulin, shuga yanga sikukula kuposa 6-6,5 mmol / l ... "Anawunikiridwa ndi George (wazaka 49):" Ziribe kanthu kuchuluka kwa mankhwala osiyanasiyana omwe amachepetsa shuga, a Diabeteson MV yekha amathandizira kupirira ndili ndi shuga. Sindimadziwa mankhwala abwino kwambiri ... "

Kuphatikiza apo, odwala matenda ashuga ambiri omwe amathandizidwa ndi Metformin adawona kuchepa kwamphamvu kwama kilogalamu angapo. Malinga ndikuwunika kwa mankhwalawa, amachepetsa chilimbikitso cha wodwalayo. Zachidziwikire, simungathe kudya popanda kudya moyenera.

Nthawi yomweyo, pali malingaliro oyipa okhudza mankhwala. Amalumikizidwa makamaka ndi kupezeka kwa zoyipa, makamaka ndi hypersensitivity, kudzimbidwa ndi kuchepa kwambiri kwa shuga.

Titha kunena kuti lililonse la mankhwalawo lili ndi zabwino komanso zovuta zake. Kukhulupirira malingaliro a anthu ena sikokwanira.

Wodwalayo ndi adokotala nawonso amasankha mtundu wa mankhwala omwe angasankhe, mogwirizana ndi mtengo wake komanso mtengo wake.

Analogs a Metformin ndi Diabeteson

Wodwala akakhala kuti wapikisana ndi mankhwala enaake kapena akumupweteketsa, dokotalayo amasintha njira yothandizira. Pachifukwa ichi, amasankha mankhwala omwe amakhalanso ndimankhwala ofanana.

Metformin ili ndi othandizira ambiri ofanana. Mwa zina mwa mankhwala omwe amaphatikiza metformin hydrochloride, Glformin, Glucofage, Metfogamma, Siofor ndi Formetin amatha kusiyanitsidwa. Tikhazikike tsatanetsatane wa mankhwala Glucofage.

Uwu ndi njira yothandiza yolimbana ndi matenda ashuga.

Mwa zina zabwino za kugwiritsa ntchito mankhwala Glucophage amatha kusiyanitsidwa:

• glycemic control;
• kukhazikika kwa shuga wamagazi;
• kupewa mavuto;
• kuwonda.

Ponena za zotsutsana, sizisiyana ndi Metformin. Kugwiritsa kwake kumakhala kochepa paubwana komanso ukalamba. Mtengo wa mankhwalawa umasiyana ndi ma ruble 105 mpaka 320, kutengera mtundu wa kumasulidwa.

Ndibwino - Glucophage kapena Diabeteson? Funso ili silingayankhidwe mosasamala. Zonse zimatengera mulingo wa glycemia, kupezeka kwa zovuta, matenda opatsirana komanso thanzi la wodwalayo. Chifukwa chake, zomwe mungagwiritse ntchito - Diabetes kapena Glucophage, zimatsimikiziridwa ndi katswiri pamodzi ndi wodwalayo.

Mwa ena mwa mankhwalawa a Diabeteson MV, Amaryl, Glyclada, Glibenclamide, Glimepiride, komanso Glidiab MV amatchuka kwambiri.

Glidiab ndi mankhwala ena omwe amasinthidwa. Pakati pazabwino za mankhwalawa, ndikofunikira kuwunikira kufunika kwake koteteza matenda a hemorheological. Amachepetsa komanso kukhazikika shuga mu odwala matenda ashuga. Mtengo wake umachokera ku ma ruble 150 mpaka 185.

Monga mukuwonera, kusiyana muzochitikazo, contraindication ndi zochitika zamankhwala zimayenera kukumbukiridwa. Koma chithandizo chamankhwala sichokhacho. Kuwona malamulo a zakudya komanso maphunziro akuthupi, mutha kuthana ndi matenda a glycemic ndikuwongolera matendawa.

Wokondedwa Wodwala! Ngati simunamwebe mankhwala a hypoglycemic, koma shuga wanu sangathe kulamulidwa ndi zakudya komanso masewera olimbitsa thupi, tengani Metformin kapena Diabeteson. Mankhwalawa amachepetsa shuga. Komabe, funsani kaye ndi dokotala wanu. Kanemayo munkhaniyi akupitiliza mutu wakugwiritsa ntchito Metformin.