Mankhwala omwe Galal adakumana nawo adapangidwira kuti athandizire komanso kupumula kwa matenda a shuga mellitus a fomu yodziyimira payekha. Mankhwala amakono apanga mitundu yambiri ya mankhwala osiyanasiyana a magulu osiyanasiyana ndi makalasi.
Ndi mankhwala ati omwe angagwiritse ntchito komanso zomwe zili bwino kwa odwala omwe ali ndi vutoli kuti aletse matenda osokoneza bongo komanso kupewa zovuta zoyipa zomwe zimatsimikiziridwa ndi dokotala yemwe amatsogolera matenda.
Mankhwala amakono amagwiritsa ntchito magulu osiyanasiyana a mankhwala kuti achepetse kuchuluka kwa glucose ndikukhalitsa kagayidwe kazakudya mthupi.
Mankhwala aliwonse ayenera kuperekedwa ndi katswiri wazachipatala.
Pankhaniyi, kudzichitira nokha kapena kusintha kwa mankhwalawa, mlingo wake umaletsedwa mwamphamvu, chifukwa zingayambitse mavuto.
Polimbana ndi matenda a matenda am'mimba, muyenera kukumbukira kuti kumwa mankhwala kuyenera kutsagana ndi kuwunika konsekonse wamagulu a shuga m'magazi.
Mpaka pano, chithandizo cha mtundu wachiwiri wa matenda a shuga ndi kugwiritsa ntchito gulu limodzi mwamagulu azida zamankhwala:
- Mankhwala omwe amachokera ku sulfonylurea. The pharmacological tingati kulimbikitsa katulutsidwe wa amkati insulin. Ammonyl ndi Diabetes ndi ena mwa mankhwala omwe amapangidwa pamaziko a sulfonylurea.
- Zogulitsa kuchokera ku gulu la Biguanide. Zotsatira zawo cholinga chake ndikuchepetsa kufunika kwa katemera wa insulin. Oyimira enieni a mankhwala amphaka awa onse akukonzekera ndi njira yayikulu yogwiritsira ntchito mankhwala a metformin hydrochloride (Glucofage).
- Mankhwala omwe amachokera ku thiazolidinol amathandizira kuchepetsa shuga m'magazi ndipo amathandizanso kusintha kwa mawonekedwe a lipid. Mankhwala oterewa m'magazi awo ndi ofanana ndi Biguanides.
- Meglitinides amathandizira kuti amasulidwe a insulin ambiri komanso kuwonjezeka kwa shuga m'magazi. Ubwino waukulu wa mankhwalawa ndikuti amakulolani kusintha shuga yokhala ndi shuga wambiri.
- Alfa glucosidase zoletsa. Zotsatira zazikulu zamankhwala zotere zimapangidwa kuti zilepheretse mayamwidwe ovuta, chifukwa chake glucose amalowa m'magazi ochepa kwambiri.
- Amayamwa.
- Zinthu zophatikiza zamankhwala, zomwe zimaphatikizapo zigawo zikuluzikulu zingapo kuchokera m'magulu omwe ali pamwambawa.
Mankhwala omwe amasankhidwa kuti alandire chithandizo ayenera kumwedwa pamankhwala omwe dokotala amafotokozera.
Kuphatikiza apo, momwe wodwalayo alili, kuchuluka kwa zochitika zolimbitsa thupi, komanso kulemera kwa thupi ziyenera kukumbukiridwa.
Kodi mankhwala a hypoglycemic ndi ati?
Mankhwala a Galvus omwe adakumana nawo ndi hypoglycemic mankhwala operekera pakamwa. Zigawo zikuluzikulu zogwiritsa ntchito mankhwalawa ndi zinthu ziwiri - vildagliptin ndi metformin hydrochloride
Vildagliptin ndi nthumwi ya kalasi ya zolimbikitsa za kanyumba kogulitsa matumba. Gawoli limathandizira chidwi cha maselo a beta kuti ilowe shuga momwe iwonongera. Tiyenera kudziwa kuti pamene zinthu zoterezi zimatengedwa ndi munthu wathanzi, palibe kusintha kwa shuga m'magazi.
Metformin hydrochloride ndi woimira gulu lachitatu-greatuanide gulu, lomwe limathandizira kuletsa kwa gluconeogenesis. Kugwiritsa ntchito mankhwala ozikidwa ndikulimbikitsa glycolysis, komwe kumapangitsa kuti glucose akhale bwino ndi maselo ndi minyewa ya thupi. Kuphatikiza apo, pali kuchepa kwa mayamwidwe am'magazi ndimaselo a m'matumbo. Ubwino wawukulu wa metformin ndikuti samayambitsa kutsika kwamphamvu m'magulu a shuga (pansi pamiyezo yokhazikika) ndipo sikuti kumayambitsa kukula kwa hypoglycemia.
Kuphatikiza apo, mapangidwe a Galvus adakumana ndi ophatikizira osiyanasiyana. Mapiritsi otere nthawi zambiri amaperekedwa kwa odwala omwe ali ndi matenda a shuga, chifukwa amathandizira kagayidwe ka lipid m'thupi, komanso amathandizira kuchepetsa kuchuluka kwa cholesterol yoyipa (kuwonjezera kuchuluka kwa zabwino), triglycerides ndi otsika kachulukidwe lipoproteins.
Mankhwalawa ali ndi mawonekedwe ogwiritsira ntchito:
- ngati chithandizo chakuchiritsa kwa matenda a shuga 2, pomwe chofunikira ndikusungabe zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi moyenera.
- kusintha zina za Galvus Met zogwira ntchito
- Ngati mankhwala sangathandize mutamwa mankhwalawa pogwiritsa ntchito mankhwala amodzi - metformin kapena vildagliptin,
- mankhwalawa zovuta ndi insulin mankhwala kapena sulfonylurea.
Galvus anakumana ndi malangizo ogwiritsira ntchito akuwonetsa kuti mankhwalawa amatengedwa kuchokera ku lumen yaying'ono m'matumbo. Chifukwa chake, mphamvu ya mapiritsi imawonedwa mkati mwa theka la ola atatha kutsata.
Chidacho chimagawanidwa mthupi lonselo, ndipo kenako chimatulutsidwa pamodzi ndi mkodzo komanso ndowe.
Kodi pali mitundu ya othandizira a hypoglycemic?
Mpaka pano, msika wogulitsa mankhwala umaphatikizapo mankhwala otere, Galvus ndi Galvus adakumana. Kusiyana kwakukulu kwa Galvusmet ndikuti nthawi yomweyo imakhala ndi zigawo ziwiri zogwira ntchito - metformin ndi vildagliptin.
Wopanga piritsi ndi kampani yopanga zamankhwala ku Germany a Novartis Pharma Production GmbH. Kuphatikiza apo, m'masitolo ogulitsa mankhwala mutha kupeza zinthu zofanana ndi zopangidwa ndi Swiss.
Mankhwala amapezeka kokha piritsi.
Kufotokozera kwa mankhwalawa m'malamulo ovomerezeka kumatanthauza kuti INN Galvus ndi vildagliptin, INN Galvus idakumana ndi vildagliptin metformin.
Musanayambe kumwa ndi Galvus, ndikofunikira kuyang'ana pamankhwala omwe alipo:
- Galvus adakumana ndi piritsi la 50 500 lolemba
- Piritsi ya Galvus Met 50 850 piritsi
- Galvus adakumana ndi mapiritsi a 50 1000 mu chipolopolo.
Chifukwa chake, manambala oyamba akuwonetsa kuchuluka kwa mamiligalamu a chinthu chomwe chili ndi vildagliptin, chachiwiri chikuwonetsa kuchuluka kwa metformin hydrochloride.
Kutengera ndi mapiritsi ndi kuchuluka kwake, mtengo wa mankhwalawa wakhazikitsidwa. Mtengo wamba wa Galvus meth 50 mg / 500 mg ndi pafupifupi ruble miliyoni ndi theka kwa mapiritsi atatu. Kuphatikiza apo, mutha kugula mankhwala ndi zidutswa 60 pa paketi iliyonse.
Malangizo ogwiritsira ntchito mapiritsi
Kugwiritsa ntchito komanso kutsata mankhwala kumayenera kuchitika ndi adokotala. Katswiri wazachipatala yekha ndiamene angasankhe bwino mlingo wa mankhwala a hypoglycemic, kutengera mtundu wa matenda.
Mukamamwa mankhwala, muyenera kuyang'anira thanzi lanu ndikuwonetsetsa kuchuluka kwa shuga m'magazi. Mlingo wosankhidwa bwino, monga lamulo, suwononga thupi la wodwalayo.
Kugwiritsa ntchito mankhwalawa kumachitika pakamwa, popanda kutafuna, koma ndimadzi ambiri.
Kuti muthane ndi mavuto omwe amabwera chifukwa chotsatira zoyipa, ndikofunikira kumwa mapiritsi pakudya. Kangati patsiku ndikofunikira kutenga wothandizira wa hypoglycemic amatsimikiziridwa payekhapayekha kwa wodwala aliyense.
Malangizo azachipatala zokhudzana ndi kuvomerezeka ndi awa:
- Kuyamba kwa njira yochizira kuyenera kuchitika pogwiritsa ntchito kuchuluka kwa metformin hydrochloride. Ichi ndichifukwa chake amalimbikitsidwa kumwa mankhwala a Galvus adakumana ndi 50/500. Kupitilira apo, katswiri wa zamankhwala amapanga chisankho pakufunika kusintha Mlingo womwe watengedwa (pamwamba).
- Kusintha kwa mankhwalawa ndi kusankha kwa mankhwalawa kumachitika malinga ndi mankhwala omwe kale amagwiritsidwa ntchito ngati hypoglycemic.
- Kwa odwala okalamba, mlingo wa mankhwalawa umatha kuchepetsedwa ngati pali zovuta zomwe zimagwira ntchito.
Njira yochizira yothandizira imayenera kutsatiridwa ndikuwunika pafupipafupi mu labotale yamisempha yambiri.
Contraindication kugwiritsa ntchito othandizira a hypoglycemic
Monga kukonzekera kulikonse kwachipatala, Galvus adakumana ndi zotsutsana zingapo komanso zoletsa kugwiritsa ntchito.
Funso la kugwiritsa ntchito mankhwalawa liyenera kutsimikiziridwa ndi adokotala okha.
Sizoletsedwa kugwiritsa ntchito wothandizira wa hypoglycemic nthawi yomwe mawonekedwe apadera a thupi kapena thupi akukhala.
Contraindication akuphatikiza ndi izi:
- machitidwe a wodwala mu mawonekedwe a tsankho kwa chimodzi kapena zingapo za mankhwala,
- ndi chitukuko cha matenda a shuga
- asanachitike kapena atachitapo kanthu opaleshoni, kuyesa kwa matenda pogwiritsa ntchito njira zina zamakono,
- ngati pali kuphwanya kwa kagayidwe kachakudya mthupi mu mawonekedwe a acetonemia,
- pakuchepa kwamthupi, popeza pamakhala chiwopsezo cha kugwira ntchito kwaimpso,
- Kulephera kwapakati kapena matenda aimpso,
- matenda opatsirana akukula kwambiri, mkhalidwe wa malungo.
- kulephera kwa chiwindi
- matenda osiyanasiyana a chiwindi, kuphatikizira hepatitis kapena cirrhosis,
- kulephera kwamtima mu mawonekedwe owopsa kapena osakhazikika, ndi kupezeka kwa myocardial infarction,
- ngati pali zovuta za kupuma zomwe zingayambitse kulephera kotere,
- uchidakwa kapena mkhalidwe woledzera wa thupi,
- kutsatira zakudya zosavomerezeka kapena kufa ndi njala (kuchuluka kwa kilocalories tsiku lililonse ndi ochepera chikwi),
- ana ochepera zaka khumi ndi zisanu ndi zitatu.
Munthawi ya bere, sikuletsedwa kugwiritsa ntchito mankhwala a hypoglycemic, popeza palibe chidziwitso chokwanira pakukula kwa mwana. Kuphatikiza apo, simuyenera kumwa mankhwala mukamayamwa.
Mpaka pano, maphunziro azachipatala sanachitike kuti adziwe zotsatira zake - kaya zinthu zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimachotsedwa pamodzi ndi mkaka wa m'mawere.
Zotsatira zoyipa komanso zovuta zoyipa
Kusagwiritsa ntchito mankhwalawa kwa hypoglycemic kumatha kuyambitsa mavuto osiyanasiyana.
Kuthekera kwa mavuto kuyenera kuganiziridwanso pakuwerengera kuchuluka kwa mankhwalawa.
Zotsatira zoyipa zotere zimayamba kuoneka mbali ya ziwalo zosiyanasiyana zamkati ndi ziwalo zamthupi.
Choyamba, zotsatira za mankhwala zimatha kusokoneza:
- Matumbo.
- Machitidwe amanjenje.
- Chiwindi.
Zotsatira zoyipa za thupi, chifukwa cha kumwa mankhwalawa, zimatha kuchitika monga:
- Kuchepetsa mseru
- kupweteka pamimba,
- kupezeka kwa gastroesophageal Reflux, izi zimawonekera pakakhala kutulutsidwa kwa chapamimba m'mimba.
- kufalikira ndi kuchuluka kwanyumba,
- matenda ashuga
- kutupa kwa kapamba mwa mawonekedwe a pancreatitis pachimake,
- kuphwanya mayamwidwe abwinobwino a mavitamini B,
- kuoneka ngati chitsulo chamkamwa,
- kupweteka mutu kapena chizungulire,
- chiwonetsero cha kunjenjemera miyendo yakumtunda,
- zotupa mu chiwindi zomwe zimasokoneza ntchito yake,
- kupweteka m'malo
- Kutupa kwa pakhungu, mawonekedwe a matuza
- kuwonjezeka kwa kuchuluka kwa uric acid, komwe kumatha kuyambitsa lactic acidosis,
- thupi lawo siligwirizana.
Ngati wodwala amamwa mankhwalawa pamlingo wapamwamba, nseru, kusanza, kupweteka kwambiri m'misempha, kupweteka m'thupi, kapena kutsika kwa shuga m'magazi ovomerezeka kumatha kuchitika.
Ngati ndi kotheka, dokotala yemwe akupezekapo akhoza kukupangitsani kusintha mankhwalawa ndi analog mankhwala (otsika mtengo kapena okwera mtengo).
Kumwa mankhwala otere, zinthu zotsatirazi ziyenera kuganiziridwa:
- Mapiritsi saloledwa kugwiritsa ntchito mukamamwa zakumwa zoledzeretsa.
- Osachepera kamodzi pamasabata angapo, kafukufuku wofufuza matenda amayenera kuchitidwa kuti adziwe momwe chiwindi ndi impso zimayendera.
- Zotsatira zosiyanasiyana za mankhwalawa zomwe zimagwiritsidwa ntchito ndi magulu ena ndi makalasi zitha kudziwika. Ichi ndichifukwa chake adotolo omwe amafunikira ayenera kudziwa kumwa mankhwala aliwonse kuti apewe kuwonetsa zovuta zomwe zimadza chifukwa chogwiritsa ntchito zovuta.
- Sitikulimbikitsidwa kuti tichite ntchito zosiyanasiyana zomwe zimafuna kuti anthu awononge chidwi.
Kuphatikiza apo, kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumatha kuyambitsa matenda a metabolic. Zotsatira zake, kuchepa kwa magazi m'thupi kapena minyewa imayamba.
Kodi maumboni a ogula ndi akatswiri azachipatala ndi ati?
About mankhwala Galvus adakumana ndi ndemanga zosiyanasiyana. Monga lamulo, kuchokera kumbali zosavomerezeka za mankhwalawo, ogula amapereka mtengo wokwera kwambiri kwa mankhwalawo. Mwambiri, kwenikweni, kuyika mapiritsi ndi mulingo wocheperako wa metformin kumasiyana m'chigawo cha rubles chikwi chimodzi ndi theka.
Tiyenera kudziwa kuti odwala ambiri alibe madandaulo chifukwa cha mtundu wawo komanso ntchito yake yabwino. Malingaliro awo, mankhwalawa amayamba kuchitapo kanthu mwachangu ndikubweretsa zotsatira zabwino. Kuphatikiza apo, mwa zina zabwino za mapiritsi oterewa ndikuti odwala matenda ashuga amatha kugula magulu ena azinthu kuchokera pamndandanda woletsedwa.
Malinga ndi madotolo, mtengo wokwera wa mankhwalawo umadzilungamitsa. Kuphatikiza apo, Metformin yokha (monga piritsi yokonzekera piritsi) siyotsika mtengo, ndipo ndalama zochulukirapo zimafunikira kuti apangidwe ndi kapangidwe ka vildaglipin.
Akatswiri azachipatala, potengera mphamvu ya mankhwalawa, adziwe kuti mulingo wotsika mtengo umakhala mulingo wamba. Kumwa mankhwalawo kumayenderana ndi kukhazikika kwa misempha ya m'magazi, kusintha kwa thupi kwambiri komanso kusintha kwamtundu wa wodwala.
Mankhwala a Hypoglycemic akufotokozedwa mu kanema munkhaniyi.
