Zoyenera kusankha: Klacid kapena Amoxiclav?

Ma Macrolides ndi penicillin ndi amodzi mwa magulu otetezeka kwambiri komanso othandiza kwambiri a antibacterial. Amagwiritsidwa ntchito pochizira matenda amkati, minofu yofewa komanso khungu. Kutengera ndi zomwe zikuwonetsa kugwiritsidwa ntchito ndi wothandizila wa causative, adotolo atha kupereka Klacid kapena Amoxiclav, komanso mankhwala ofanana mu kapangidwe kake ndikuwakhudza (Clarithromycin, Augmentin, Sumamed).

Chikhalidwe cha Klacid

Chomwe chimagwira ku Klacid ndi macrolide antioxylacithithcinacotic. Kuwonekera kwa ntchito yake ya antibacterial kumafikira tizilombo toyambitsa matenda ambiri opatsirana. Tizilombo tomwe tili ndi nkhawa:

• gram-positive ndi gram-negative aerobic bacteria (streptococci, pneumococci, moraxella, hemophilus bacillus, listeria, etc.);
• tizilombo toyambitsa matenda a anaerobic (clostridia, etc.);
• wothandizila panusative wa STDs (chlamydia, mycoplasma, ureaplasma);
• toxoplasma;
• Borrelia
• Helicobacter pylori (H. pylori);
• mycobacteria (musamawonetsetse mphamvu zokwanira pokhapokha mutapatsidwa kachilombo ka chifuwa chachikulu).

Klacid ndi Amoxiclav amagwiritsidwa ntchito pochizira matenda amkati, minofu yofewa komanso khungu.

Makulidwe ochulukirapo a imprithromycin amalola kupatsa Klacid zotsatirazi:

• matenda oyambitsidwa ndi bakiteriya a m'munsi komanso m'munsi mwa kupuma (sinusitis, tonsillitis, pharyngitis, media atitis, tracheobronchitis, chibayo cha atypical, etc.);
• folliculitis, erysipelas, zotupa zina za pakhungu ndi zotumphukira minofu;
• matenda amtundu komanso azachilengedwe oyambitsidwa ndi mycobacteria (kupatula bacillus wa Koch);
• prophylaxis ya mycobacterial matenda okwiyitsidwa ndi a aumum mwa odwala omwe ali ndi kachilombo ka HIV omwe ali ndi zotsika za T-assist;
• zilonda zam'mimba ndi zilonda zam'mimba za duodenal (kuti muchepetse kuchuluka kwa H. pylori ngati gawo limodzi la maphunziro a antibacterial);
• Matenda opatsirana omwe amayambitsidwa ndi tizilombo toyambitsa matenda omwe amakhudzidwa ndi clearithromycin;
• kupewa mabakiteriya pambuyo mano mano (kuphatikizapo sepsis ndi endocarditis).

Kutengera ndi kupezeka kwa wodwala komanso zaka zake, adokotala atha kukufotokozerani imodzi mwanjira zotsatirazi zotulutsidwa ndi Klacid:

• mapiritsi (kipimo cha yogwira pophika - 250 ndi 500 mg);
• kuyimitsidwa (kuchuluka kwa maantibayotiki mu 5 ml ya chinthu chotsirizidwa ndi 125 kapena 250 mg);
• ufa pakukonzekera kulowetsedwa njira (mlingo wa clarithromycin - 500 mg mu 1 botolo).

Chomwe chimagwira ku Klacid ndi macrolide antioxylacithithcinacotic.

Klacid sinafotokozedwe jekeseni: makonzedwe amkati mwa macrolide amachitika kukapumira kwa ola limodzi kapena nthawi yayitali.

Zoyipa zomwe zimagwiritsidwa ntchito pacacithromycin ndi:

• Hypersensitivity ku macrolide ndi mankhwala a ketolide, zosakaniza zina za mankhwala;
• kulephera kwa mtima, matenda a mtima, corricary arrhythmia ndi tachycardia, kupezeka kwa zinthu za proarrhythmogenic ndi chiwopsezo chowonjezereka cha kukulira kwa nthawi ya QT (mwachitsanzo, kuchepa kwa potaziyamu ndi magnesium);
• kuphatikiza kwa impso ndi chiwindi kulephera;
• cholestatic jaundice, wokwiyitsidwa ndi kugwiritsa ntchito mankhwalawa (mbiri yakale);
• kuyamwa
• mimba (mu trimester ya 2-3, n`zotheka kugwiritsa ntchito malingana ndi mawonekedwe okhwima);
• zaka zosakwana miyezi 6;
• matenda a porphyrin;
• mankhwala omwe ali ndi mankhwala osagwirizana ndi clarithromycin (Ergotamine, Colchicine, Ticagrelor, Midazolam, Ranolazine, Cisapride, Astemizole, Terfenadine, statins, ndi zina).

Ngati chiwindi chimagwira ndi matenda a impso (ngati Cl creatinine ndi yocheperako, koma yoposa 30 ml / min), chithandizo chakufotokozeraku chithandizidwe kuyenera kuchitika moyang'aniridwa ndi achipatala komanso kuwunika ma biochemistry. Mukamapereka mankhwala a Klacid kuyimitsidwa kwa odwala omwe ali ndi matenda osokoneza bongo, kuchuluka kwa mankhwala omwe amafunikira pakhungu kuyenera kuganiziridwanso.

Mukamapereka mankhwala a Klacid kuyimitsidwa kwa odwala omwe ali ndi matenda osokoneza bongo, kuchuluka kwa mankhwala omwe amafunikira pakhungu kuyenera kuganiziridwanso.

Makhalidwe a Amoxiclav

Amoxiclav imakhala ndi antibacterial complication (amoxicillin) ndi beta-lactamase inhibitor (clavulanic acid). Clavulanic acid imalepheretsa ma enzyme omwe amapha mphete ya beta-lactam. Kuphatikizidwa kwazinthu ziwirizi kumakupatsani mwayi woti muchitepo kanthu kuphatikizapo ndi tizilombo tosaoneka ndi ma penicillin osatetezedwa.

Kuwonekera kwa ntchito ya amoxicillin kufalikira kwa tizilombo toyambitsa matenda:

• gram zabwino aerobic tizilombo (staphylococci, streptococci, pneumococci);
• gram-negative aerobic cocci (hemophilic ndi Escherichia coli, moraxella, Klebsiella, enterobacteria).

Zowonetsa kugwiritsa ntchito mankhwalawa ndi izi:

• bakiteriya matenda am'munsi komanso m'munsi kupuma;
• yotupa njira ya kwamikodzo chifukwa cha aerobic tizilombo;
• matenda am'mimba (zilonda zam'mimba ndi zilonda zam'mimba, kutupa kwa ndulu ndi ma ducts a bile);
• matenda opatsirana a kubala;
• matenda odontogenic, kupewa mabakiteriya pambuyo pakuchita mano;
• osteomyelitis, matenda a minofu;
• bakiteriya zotupa khungu ndi subcutaneous minofu;
• kwa mtsempha wa magazi a Amoxiclav: STD (gonorrhea, chancre yofatsa), kutupa kwamkati pamimba, kupewa zovuta pambuyo pa opaleshoni.

Amoxiclav imapezeka mitundu ingapo:

• mapiritsi (Mlingo wa amoxicillin ndi 250, 500 kapena 875 mg);
• mapiritsi otayika (sungunuka) (ali ndi 500 kapena 875 mg wa antiotic);
• lyophilisate kuti apange makonzedwe a mtsempha wa mtsempha wa magazi (muyezo wa antibacterial mu 1 botolo la lyophilisate ndi 500 mg kapena 1 g);
• ufa wopangira kuyimitsidwa (5 ml ya mankhwala omaliza amakhala ndi 125, 250 kapena 400 mg ya chinthu chogwira, kutengera mlingo womwe umawonetsedwa).

Amoxiclav imakhala ndi antibacterial complication (amoxicillin) ndi beta-lactamase inhibitor (clavulanic acid).

Contraindication kuti mutenge Amoxiclav ndi ma pathologies monga:

• Hypersensitivity mankhwala a penicillin ndi magulu a cephalosporin, komanso monobactam ndi carbapenem;
• thupi lawo siligwirizana ndi kagayidwe kachakudya matenda owonjezera a Amoxiclav (phenylketonuria);
• matenda monocytic tonillitis;
• lymphocytic leukemia;
• kuwonongeka kwa hepatic ntchito chifukwa cha amoxicillin mankhwala (mbiri);
• Mukamapereka mapiritsi omwera omwera a Amoxiclav: kulemera kochepera 40 makilogalamu, ubwana (mpaka zaka 12), kulephera kwambiri kwaimpso (Cl creatinine <30 ml / min.).

Mochenjera, Amoxiclav amalembera chiwindi ndi impso matenda, chithandizo ndi anticoagulants, mbiri ya matenda am'mimba oyambitsidwa ndi antibacterial mankhwala, chifukwa mkaka wa m'mawere ndi pakati.

Kuyerekeza kwa Klacid ndi Amoxiclav

Zizindikiro zakusankhidwa kwa Amoxiclav ndi Klacid ndi zofanana. Kusintha kofananira kosiyanasiyana kumachitika chifukwa cha kusiyana kwa mawonekedwe a antibacterial zochita, mtengo komanso chitetezo cha mankhwala.

Kufanana

Zofanana pamankhwala onsewa ndi:

1. Mitundu yosiyanasiyana ya antibacterial.
2. Nthawi yovomerezeka ya chithandizo (masiku 5 mpaka 14) komanso pafupipafupi kumwa maantibayotiki (2 kawiri pa tsiku).
3. Momwe mungachokere ku pharmacies (pa mankhwala).
4. Kuthandiza motsutsana ndi mabakiteriya opanga beta-lactamases.
5. Kugwiritsidwa ntchito kwa zovuta pa zilonda zam'mimba zomwe zimakwiya ndi H. pylori.

Kodi pali kusiyana kotani?

Kusiyana pakati pa Klacid ndi Amoxiclav ndikofunikira kwambiri. Kusiyana kwa mankhwala kumawonedwa pazinthu monga:

1. Gulu la Chitetezo cha FDA. Amoxicillin amakonda kwambiri kugwiritsidwa ntchito ndi amayi oyembekezera.
2. Kutheka kwa ntchito pa mkaka wa m`mawere. Amoxiclav amaloledwa kugwiritsidwa ntchito poyamwitsa, ndipo Klacid ndi osavomerezeka.
3. Msinkhu wochepera pomwe mankhwalawa angagwiritsidwe ntchito. Amoxicillin wothandizila amatha kupatsidwa kwa ana kuyambira masiku oyamba amoyo. Klacid amamulembera makanda azaka zopitilira 6.
4. Tsiku lililonse achire mlingo wa antiotic. Mukalandira chithandizo ndi Amoxiclav, ndi 750-1750 mg, ndi Klacid - 500-1000 mg.
5. Zosintha zosiyanasiyana. Clacid amadziwika ndi zotsatira zoyipa pafupipafupi kuchokera ku dongosolo lamkati lamanjenje (kumva kuwawa ndi kununkhira, kusowa tulo, kupweteka mutu).

Amoxicillin amakonda kwambiri kugwiritsidwa ntchito ndi amayi oyembekezera.

Amoxiclav amaloledwa kugwiritsidwa ntchito poyamwitsa, ndipo Klacid ndi osavomerezeka.

Clacid amadziwika ndi zotsatira zoyipa pafupipafupi kuchokera ku chapakati mantha dongosolo (kusowa tulo).

Zomwe zimakhala zotsika mtengo

Ndi nthawi yofanana ya mankhwala, Klacid amawononga mtengo wowonjezera katatu kuposa Amoxiclav. Kuwerengera kwa mtengo wa maphunzirowa kumatengera machitidwe a antibayotiki.

Zomwe zili bwino: Klacid kapena Amoxiclav

Kusankha kwa mankhwalawa kumachitika ndi dokotala potengera momwe wodwalayo awazindikira, mtundu wa omwe amamuthandiza ndi mbiri yachipatala.

Amoxiclav amatengedwa ngati mankhwala posankha matenda a kupuma kwamomwe amayamba chifukwa cha tizilombo toyambitsa matenda. Ndiotetezeka kwa magulu ovutikitsitsa a odwala.

Klacid nthawi zambiri amalembedwa kwa odwala akuluakulu omwe ali ndi matenda opatsirana pogonana, matenda oopsa kwambiri komanso am'deralo.

Ndemanga za Odwala

Maria, wazaka 31, Astrakhan

Mwana nthawi zambiri amakhala ndi vuto la kummero (tonsillitis, pharyngitis). M'mbuyomu, adotolo adatchula Amoxicillin ndi mawonekedwe ake, koma nthawi iyi maantibayotiki sanathandize, sanathenso kutentha. Pambuyo pamasiku atatu odwala, mankhwalawa adasinthidwa kukhala Klacid. Pa tsiku lachiwiri lovomerezeka, kutentha kunatsika kwambiri, ndipo mwanayo anayamba kuchira.

Ndine wokhutira ndi zomwe zimachitika, koma mankhwalawa ali ndi zotsatira zoyipa - nseru.

Olga, wazaka 28, Krasnodar

Amoxiclav ndi chida chachikulu chowonera chomwe chimatha bwino ntchito yake. Mankhwalawa adamulembera matenda a mwana wake, ali ndi chaka chimodzi chokha. Mwanayo anali wokondwa kumwa mankhwalawo m'njira yoyimitsidwa, ndipo atatha masiku 1-2 zotsatira zake zinali zowoneka kale.

Mankhwalawa ndi oyeneranso achikulire, motero ndikofunika kusunga mapiritsi ndi ufa m'nyumba yamatendawa kunyumba.

Madotolo amakambirana za Klacid ndi Amoxiclav

Bakieva E.B., Dokotala wamano, Ufa

Klacid ndi mankhwala abwino, othandiza kuchokera kwa wopanga waku Germany. Imagwira ntchito pothana ndi mabakiteriya ambiri omwe amalimbana ndi mankhwala achilengedwe. Ili ndi kutentha kwakukulu kwa mafupa ndi mano, chifukwa chake imagwiritsidwa ntchito mosamala mu mano ndi opareshoni.

Ndimapereka mankhwala kwa odwala omwe ali ndi osteomyelitis, periostitis, odontogenic sinusitis ndi matenda oyamba ndi mabakiteriya a kupuma dongosolo (tonillitis, pharyngitis).

Cholinga choyipa ndichovuta chamtundu wamatumbo (matenda am'mimba, dyspepsia, nseru).

Almasri A.M., gastroenterologist, Moscow

Amoxiclav nthawi zambiri amalembera matenda kupuma, koma mankhwalawa amapereka mphamvu zina (monga, zilonda zam'mimba, cholecystitis, etc.). Maantibayotiki amapezeka m'njira zingapo ndipo ndi osavuta kugwiritsa ntchito. Ubwino wina ndi mtengo wotsika mtengo.

Mankhwala, vuto la chopondapo limakhala lotheka, ndipo candidiasis nthawi zambiri imayamba pambuyo pakukonzekera.