Momwe mungagwiritsire ntchito mankhwala a NovoMix 30 Penfill?

NovoMix 30 Penfill ndi mankhwala a hypoglycemic potengera mitundu iwiri ya insulin. The pancreatic homoni yochepa ikuthandizira kuti muchite bwino kwambiri pochiritsa, pomwe insulin yokhala ndi nthawi yayitali imakupatsani mwayi wokhala ndi hypoglycemic masana. Mankhwala a insulin ndi oletsedwa kugwiritsidwa ntchito ndi odwala osakwana zaka 18 ndipo amaloledwa kugwiritsidwa ntchito ndi amayi apakati, oyembekezera.

Dzinalo Losayenerana

Biphasic aspart wa insulin.

NovoMix 30 Penfill ndi mankhwala a hypoglycemic potengera mitundu iwiri ya insulin.

ATX

A10AD05.

Kutulutsa mafomu ndi kapangidwe kake

Mlingo wa mawonekedwe - kuyimitsidwa kwa makina oyang'anira. 1 ml ya zakumwa zili ndi 100 IU yophatikizira ntchito, yophatikiza 70% ya insulini protamine aspart monga makhiristo ndi 30% ya insulin ya sungunuka. Kuti muwonjezere mfundo za pharmacokinetic, zinthu zothandizira zimawonjezeredwa pazinthu zomwe zimagwira ntchito:

• glycerol;
• carbolic acid;
• sodium chloride ndi zinc;
• metacresol;
• dihydrogenated sodium hydrogen phosphate;
• protamine sulfate;
• sodium hydroxide;
• 10% hydrochloric acid;
• madzi osalala a jakisoni.

Mankhwalawa adatsekeka m'mabotolo atatu a 3 ml okhala ndi 300 IU yogwira ntchito. NovoMix Penfill (Flexpen) imapezekanso mu cholembera.

Zotsatira za pharmacological

NovoMix imayimira insulini yokhala ndi magawo awiri, yopanga fanizo la mahoney pancreatic ya anthu:

• 30% yosungunulira yocheperako;
• 70% protamine insulin makhiristo ndi pafupifupi kutalika mphamvu.

NovoMix imayambitsa insulin.

Insulin aspart imapangidwa pogwiritsa ntchito ukadaulo womwe umapangidwanso mu DNA kuchokera ku yisiti yophika mkate.

Zotsatira za hypoglycemic zimachitika chifukwa chomangiriza ma spart to insulin receptors pa membrane wakunja wa myocyte ndi ma cell a adipose. Mofananamo, kuletsa kwa gluconeogenesis m'chiwindi kumachitika ndipo mayendedwe amtundu wa glucose amawonjezeka. Chifukwa chokwaniritsa njira yochizira, ziwalo zathupi zimagwira mosavuta shuga ndikuwupanga mphamvu.

Zotsatira za mankhwalawa zimawonedwa kwa mphindi 15 mpaka 20, mpaka zimafika patatha maola 2-4. Zotsatira za hypoglycemic zimatha maola 24.

Pharmacokinetics

Chifukwa cha kukhalapo kwa Aspartic acid, insulini aspart imakhala yokwanira 30% mozama kwambiri pamtundu wamafuta akhungu a khungu, mosiyana ndi insulin. Akalowa m'magazi, zinthu zomwe zimagwira zimafikira ndende yamagazi ambiri mkati mwa mphindi 60. Kuchotsa theka moyo kumapangitsa mphindi 30.

Zisonyezo za insulin zimabwereranso kuzikhalidwe zawo zoyambirira mkati mwa maola 15-18 pambuyo pa kuperekedwa kwa sc. Mankhwala amaphatikizidwa m'chiwindi ndi impso. Zinthu zopangidwa ndi ma metabolism zimasiya thupi chifukwa cha kusefera kwa glomerular.

Akalowa m'magazi, zinthu zomwe zimagwira zimafikira ndende yamagazi ambiri mkati mwa mphindi 60.

Zizindikiro zogwiritsidwa ntchito

Mankhwala a insulin ndi omwe amapatsidwa zotsatirazi:

• matenda a shuga a insulin;
• shuga osadalira insulin wokhala ndi zolepheretsa zopatsa thanzi, kuwonjezera masewera olimbitsa thupi komanso njira zina zochepetsera thupi.

Contraindication

Mankhwala saloledwa kuperekedwa kwa anthu omwe ali ndi chiwopsezo chachikulu cha mankhwala omwe amapanga hypoglycemic wothandizira. Insulin yamtunduwu si yoyenera kwa anthu ochepera zaka 18.

Ndi chisamaliro

Odwala ndi mkhutu zinchito ntchito ya chiwindi ndi impso pa nthawi ya insulin mankhwala ayenera kuwunika boma la ziwalo. Kusagwira bwino ntchito kwawo kungayambitse insulin metabolism.

Anthu omwe ali ndi vuto la kufalikira kwa ubongo ndi kusakhazikika kwa mtima ayenera kusamala.

Anthu omwe ali ndi vuto la ubongo amayenera kusamala.

Momwe mungatengere NovoMix 30 Penfill

Mankhwalawa amaperekedwa pokhapokha. Intramuscularly ndi mtsempha wa magazi amaletsedwa chifukwa cha kupezeka kwa hypoglycemia.

Mlingowo umatsimikiziridwa ndi dokotala kutengera ndi zomwe munthu akuwonetsa za shuga ndi kufunika kwa insulin. Odwala omwe ali ndi shuga omwe amadalira insulin atha kupatsidwa mankhwala olembetsedwa monga NovoMix monga monotherapy ndi insulin komanso osakanikirana ndi othandizira a hypoglycemic. Kwa matenda a shuga a 2, tikulimbikitsidwa kuti muyambe kugwiritsa ntchito NovoMix ndi muyeso wama 6 mayunitsi musanadye komanso madzulo. Jekiseni amaloledwa ndi magawo 12 a mankhwalawa jakisoni imodzi patsiku musanadye.

Njira Yophatikiza ndi Insulin

Musanagwiritse ntchito, onetsetsani kuti kutentha kwa zomwe zili mu katiriji zikufanana ndi kutentha kwa chilengedwe. Pambuyo pake, sakanizani insulin malinga ndi algorithm otsatirawa:

1. Poyamba gwiritsani ntchito cartridge maulendo 10 pakati pa kanjedza pamalo opingasa maulendo 10.
2. Kwezani cartridge molunjika maulendo 10 ndikutsitsa molunjika kuti galasi la galasi liyende kutalika konse kwa cartridge. Kuti muchite izi, ndikokwanira kupukutira nkono m'chigawo cholumikizira.
3. Mukamaliza kubwezeretsa, kuyimitsidwa kumayenera kukhala kwamitambo ndikupanga tint yoyera. Izi ngati sizichitika, njira zosakanikirana zimabwerezedwa. Madzi akangosakanikirana, insulin imayenera kubayidwa nthawi yomweyo.

Kuyambitsa kulikonse kumachitika ndi singano yatsopano.

Pakukhazikitsidwa kwa zinthu zosachepera khumi ndi ziwiri za zinthu zofunikira. Ngati mtengo wa insulini ndi wotsika, ndiye kuti muyenera kusintha kabati ndi watsopano.

Momwe mungagwiritsire ntchito cholembera

Musanagwiritse ntchito cholembera, yang'anani kutsatira ndi mtundu wa insulin. Pamaso pa jekeseni woyamba, umasakanizika bwino.

Kuyambitsa kulikonse kumachitika ndi singano yatsopano. Kusintha chinthu ndikofunikira kuti muchepetse kuthekera kwa matenda. Musanagwiritse ntchito, onetsetsani kuti singanoyo siinakupindika kapena kuwonongeka. Kuti muphatikize singano, muyenera kutsatira ma algorithm otsatirawa:

1. Chotsani chivundikiro kuchokera ku zotayikirazi, ndiye kuti ndikupotera singano pa cholembera.
2. Chipewa chakunja chimachotsedwa koma osatayidwa.
3. Amachotsa kapu wamkati.

Ngakhale kugwira ntchito moyenera kwa NovoMix, mpweya umatha kulowa mu cartridge. Chifukwa chake, musanagwiritse ntchito cholembera, ndikofunikira kuti musalowe mu minofu pochita izi:

1. Imbani 2 mayunitsi ndi chosankhira mlingo.
2. Kugwira FlexPen molunjika ndi singano mmwamba, dinani mopepuka pa cartridge ndi chala chanu maulendo 4-5 kuti mlengalenga wa mpweya usunthire pamwamba pa cartridge.
3. Kupitiliza kugwirizira cholembera pang'onopang'ono, kanikizani valavu yoyambitsa njira yonse. Onani kuti wosankhidwa wa mankhwalawo wabwerera m'malo 0 ndipo dontho la mankhwalawo limawonekera pamsonga pa singano. Ngati palibe mankhwala, ndiye kuti muyenera kubwereza njirayi. Ngati, patadutsa nthawi 6, insulini simalowa kudzera mu singano, izi zikuwonetsa kuyipa kwa FlexPen.

Musanagwiritse ntchito, onetsetsani kuti singanoyo siinakupindika kapena kuwonongeka.

Mlingo wakhazikitsidwa pogwiritsa ntchito chosankha, chomwe chiyenera kukhala pamalo 0. Osankhidwa kuti asankhe kuchuluka kwake atha kuzunguliridwa nthawi yomweyo komanso mawola. Koma mkukonzekera muyenera kusamala - simungathe kukanikiza valavu yoyambira, apo ayi padzakhala kutulutsidwa kwa insulin. Nambala 1 ikufanana ndi gawo limodzi la insulin. Osakhazikitsa mlingo wopitilira kuchuluka kwa insulini yotsalira mukatoni.

Kuti mugwiritse ntchito jakisoni, muyenera kukanikiza valavalo wanjira yonse mpaka mawonekedwe 0 awonetsedwa pa chosankha ndipo singano ikadali pansi pa khungu. Mukayika ziro pazenera, kusiya singano pakhungu kwa masekondi 6, chifukwa chomwe insulin idzayambitsidwa kwathunthu. Mukamayambitsa, wosankhidwa sayenera kuloledwa kuzungulira, chifukwa ikazunguliridwa, insulin sidzamasulidwa. Pambuyo pa njirayi, ikani singano mu kapu yakunja ndikuvula.

Zotsatira zoyipa za NovoMix 30 Penfilla

Zotsatira zoyipa nthawi zambiri zimapwetekedwa ndi kusankha kosayenera kwa mankhwalawa kapena kugwiritsa ntchito molakwika mankhwalawa.

Pa mbali ya gawo la masomphenyawo

Matenda amphongo amaphatikizidwa ndi kakonzedwe ka zolakwa zoyesayesa komanso matenda ashuga a retinopathy.

Pakati mantha dongosolo

Kusokonezeka kwamitsempha yamanjenje kumadziwika m'machitidwe osowa kwambiri mwa mawonekedwe a zotumphukira za polyneuropathy. Mwina kukula kwa chizungulire ndi mutu.

NovoMix 30 Penfill ikhoza kuyambitsa chizungulire.

Pa khungu

Jekeseni wa subcutaneous amayenera kuyikidwa m'malo osiyanasiyana mkati mwa malo omwewo kuti tipewe kukula kwa lipodystrophy. Mwina kuwoneka kwa zimachitika pamalo jakisoni - kutupa kapena kufiyira. Mawonekedwe a mziwopsezo mu mawonekedwe a zotupa kapena kuyabwa kumachoka paokha pamene mulingo wachepetsedwa kapena mankhwala atachotsedwa.

Kuchokera ku chitetezo chamthupi

Matenda osadzitchinjiriza amatayidwa ndi mawonekedwe a:

• urticaria;
• Khungu;
• zotupa
• matenda ammimba;
• kuvutika kupuma
• kutuluka thukuta kwambiri.

Kuchokera kumbali ya kagayidwe

Matenda a metabolism amadziwika ndi kutaya kwa glycemic control. Kukula kwa hypoglycemia sikumayikidwa padera, makamaka ndi kugwiritsidwa ntchito kofanana ndi mankhwala amkamwa a hypoglycemic.

Odwala omwe akuwonekeratu kuti anaphylactic zimachitika ali pachiwopsezo chodwala anaphylactic.

Matupi omaliza

Odwala omwe amawaganizira kuti angachitike ndi anaphylactic, pamakhala chiwopsezo cha mantha anaphylactic, angioedema a lilime, pakhosi, ndi khosi. Ndi tsankho la munthu payekhapayekha, kapangidwe ka khungu kangachitike.

Malangizo apadera

Ngati mulibe mankhwala okwanira a hypoglycemic wothandizapo kapena ngati muthana nawo mwachangu, hyperglycemia imayamba. Kutsekemera kwa seramu yayikulu kumatha kuyambitsa matenda a diabetes ketoacidosis ngati wodwala salandila chithandizo choyenera. Chiwopsezo chokhala ndi matenda a pathological chimawonjezeka mwa odwala omwe ali ndi matenda a shuga 1. Hyperglycemia imadziwika ndi mawonekedwe a zotere:

• ludzu lalikulu;
• polyuria ndi pokodza pokodza;
• redness, peeling, khungu lowuma;
• zosokoneza tulo;
• kutopa kwambiri;
• kusanza ndi kusanza;
• ziume zowuma pakamwa;
• kununkhira kwa acetone pa kuphipha.

Hyperglycemia imadziwika ndi mawonekedwe a ludzu lalikulu.

Hyperglycemia imadziwika ndi mseru komanso kusanza.

Hyperglycemia imadziwika ndi zovuta kugona.

Hyperglycemia imadziwika ndi kutopa kwambiri.

Ndi zochitika zolimbitsa thupi, zosagwirizana ndi mankhwala kapena kudya jakisoni, hypoglycemia imayamba.

Gwiritsani ntchito mu ukalamba

Odwala azaka zopitilira 65 safunika kusintha mlingo.

Kukhazikitsidwa kwa NovoMix 30 Penfil kwa ana

Ndi zoletsedwa kupaka mankhwalawa ana osaposa zaka 18 chifukwa chosakwanira kudziwa zambiri za insulin yophatikizira ana ndi achinyamata.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mankhwala a insulin amathandizira kuchepetsa shuga kwa amayi panthawi yomwe ali ndi pakati. Aspart ya insulin siyikukhudza masoka kukula kwa mluza ndipo sayambitsa intrauterine. Mankhwalawa samadutsa mkaka wa m'mawere, kotero amatha kugwiritsidwa ntchito pakutsuka.

Mankhwala ochulukirapo a NovoMix 30 Penfill

Pogwiritsa ntchito mankhwala osokoneza bongo a hypoglycemic, zizindikiro za bongo zingachitike. Chithunzi cha chipatala chimadziwika ndi kupindika pang'onopang'ono kapena kwakuthwa kwa hypoglycemia, kutengera mlingo womwe umaperekedwa. Ndi kuchepa pang'ono kwa shuga, mutha kuthana ndi njira yothandizira pokhazikitsa shuga, confectionery kapena zakudya zopatsa mphamvu. Chifukwa cha kupezeka kwa hypoglycemia, tikulimbikitsidwa kuti odwala matenda ashuga azitha kudya nawo shuga wambiri.

Pankhani ya hypoglycemia, wodwala amasiya kuzindikira.

Pankhani ya hypoglycemia, wodwala amasiya kuzindikira. Mwadzidzidzi, amafunika kuti apange jakisoni wam'mimba kapena wocheperako wa 0,5 kapena 1 mg wa glucagon pansi pazovuta, 40% dextrose solution itha kuperekedwa kudzera mu mtima ngati wodwalayo sakudziwitsidwa.

Kuchita ndi mankhwala ena

Kusagwirizana kwazachipatala kwa NovoMix ndi mankhwala ena kunawululidwa panthawi yoyesedwa. Kugwiritsanso ntchito komweko kwa mankhwala ena kumabweretsa kukulira kapena kuchepa kwa zotsatira za hypoglycemic.

Kuyenderana ndi mowa

Ethanol amathandizira kuti kutayika kwa glycemic control. Mowa umakulitsa kapena kufooketsa mphamvu ya mankhwalawo, chifukwa chake simuyenera kumwa mowa mukamalandira chithandizo.

Kugwiritsanso ntchito komweko kwa mankhwala ena kumabweretsa kukulira kapena kuchepa kwa zotsatira za hypoglycemic.

Analogi

Kusinthira ku mtundu wina wa insulin kumachitika moyang'aniridwa ndi achipatala. Kuchokera pakusiyanitsa:

• Vosulin;
• Gensulin;
• Insuvit;
• Insugen;
• Insuman;
• Mikstard;
• Humodar.

Kupita kwina mankhwala

Mankhwalawa atha kugulidwa kokha ndi mankhwala.

Kodi ndingagule popanda kulandira mankhwala?

Kugwiritsa ntchito molakwika mankhwala, hypoglycemia imatha kukhazikika, chifukwa chake, mankhwala a insulin popanda zisonyezo zachipatala oletsedwa.

Mtengo

Mtengo wapakati wa wothandizira wa hypoglycemic ndi 1821 rubles.

Zosungidwa zamankhwala

Makatoni amasungidwa m'malo amdima pa kutentha kwa + 2 ... + 8 ° C popanda kuzizira.

Tsiku lotha ntchito

Zaka 2

Wopanga

Novo Nordisk, Denmark.

Ndemanga

Tatyana Komissarova, wazaka 22, Yekaterinburg

Mimba, ndimadwala matenda a shuga ochititsa chidwi chifukwa ndimatsatira kudya zakudya zowerengera komanso kuwerengera chakudya. Koma izi sizinathandize: mutatha kudya shuga udakwera 13 mmol. Endocrinologist adalemba NovoMix insulin mankhwala, ndipo adaletsa kumwa mapiritsi a hyperglycemia. Kugundidwa 2 pa tsiku kwa mphindi 5 musanadye komanso Levemir 2 mayunitsi musanagone. Ndaphunzira kugwiritsa ntchito cholembera, chifukwa ndi yabwino kuposa jakisoni. Njira yothetsera vutoli siyoyambitsa, koma nthawi zina mikwingwirima imabuka. Shuga amabwereranso nthawi yomweyo. Ndisiyira ndemanga zabwino.

Stanislav Zinoviev, wazaka 34, Moscow

Zaka 2 jekeseni wa NovoMix. Ndili ndi matenda ashuga a 2, chifukwa ndimangogwiritsa ntchito zolembera zokha ndipo sindimamwa mapiritsi. Mankhwalawa amachepetsa shuga mpaka 6.9-7.0 mmol ndipo amakhala ndi maola 24. Ngati mumadumphira jakisoni, ndiye kuti izi sizotsutsa - mankhwalawa amatha kugwiritsidwa ntchito limodzi ndi mitundu ina ya insulin.Chachikulu ndichakuti mlingo uyenera kutsatira malangizo.