Pa intaneti, sizovuta kupeza zidziwitso za Metformin ndi kuwunikira kwa iwo omwe akuchepetsa thupi za mankhwalawa, zomwe zikuwonetsa kuti chida ichi chimagwiritsidwanso ntchito pakuchepetsa thupi.
Kulemera kwambiri kumatha kuonedwa ngati vuto limodzi lachitukuko chamakono. Mwachitsanzo, kuthamanga kwa moyo komwe kumayambitsa kupsinjika mosalekeza, kupsinjika, kupezeka kwa chakudya, ndipo nthawi zambiri osati kwambiri komanso wathanzi.
Kunenepa kwambiri sikudutsa popanda kufunafuna thupi. Uwu ndi katundu pama joo, ndi cholesterol yambiri, komanso chiwopsezo cha matenda amtima. Choopsa kwambiri ndichakuti kunenepa kwambiri pamimba, komwe m'masitolo amafuta mumakhala matumbo ndi matumbo apamwamba, zomwe zimapangitsa kuti chiwopsezo cha sitiroko, matenda a coronary, ndi khansa.
Pazifukwa zonsezi, kugwiritsa ntchito Metformin pochizira kunenepa kwakanthawi kumawoneka kukhala kosamveka. Koma musanayambe chithandizo, ndikofunikira kudziwa ngati mankhwalawo amathandizadi kuchepetsa thupi komanso momwe mungatenge Metformin molondola.
Kufotokozera kwa mankhwalawa
Metformin ndi mankhwala ogwiritsidwa ntchito pochiza matenda a shuga 2, ndimwambo wogwiritsanso ntchito mankhwalawa prediabetes, gestational kishuga komanso polycystic ovary syndrome. Chizindikiro cha kuperekedwa kwa mankhwalawa ndi wodwala wonenepa kwambiri kapena wonenepa kwambiri, ngati palibe kuphwanya impso. Kuphatikiza pazomwe tafotokozazi, mutha kutenga Metformin pochiza matenda ena omwe kukana insulin ndikofunikira.
Mankhwalawa ali ndi mawonekedwe osiyanasiyana mthupi la munthu:
- Imatsitsa misempha ya shuga mwa kuletsa njira ya gluconeogeneis - njira yopangira glucose m'chiwindi.
- Zimawonjezera kukhudzika kwa minofu ku insulin.
- Imalimbikitsa kukhathamiritsa kwa mafuta acids.
- Zimalepheretsa kuyamwa kwa glucose m'matumbo.
- Imathandizira kusunthira kwa glucose kudzera mu nembanemba kulowa mu minofu, chifukwa chake, kutulutsa kwa glucose kumatheka.
- Amachepetsa kuchuluka kwa LDL, cholesterol ndi TG mu seramu yamagazi.
Ngakhale zovuta zingapo, Metformin ili ndi zotsutsana ndipo imatha kuyambitsa mavuto.
Ikhoza kukhala yopweteka m'mimba komanso kupweteka kwa m'mimba - vuto lomwe lingakhale loopsa kwa wodwala matenda ashuga.
Metformin yodziyimira kulemera
Poyamba, mankhwalawa ankangogwiritsidwa ntchito ngati mankhwala antidiabetes. Pambuyo pake, popanga kafukufuku pakati pa akatswiri othamanga komanso omanga thupi, zinaonekeratu kuti Metformin imathandizira kuchepetsa thupi.
Kutsika kowoneka bwino kwamafuta a thupi mukatenga Metformin ndi chifukwa cha zifukwa zingapo. Kuzunza kwambiri mosavomerezeka kumabweretsa kuchepa kwa chidwi cha minyewa kupita ku insulin - mahomoni a kapamba, omwe amachititsa kuti shuga azikhala ndi maselo ambiri. Ngati maselo amenewa amayamba kugonjetsedwa, ndiye kuti, insulin, ndiye kuti sangalandire shuga kuchokera m'magazi. Kuti athandize kufooka kwa shuga, kapamba amayamba kupanga insulini yambiri, chifukwa chake, kuphatikiza kwake m'magazi kumakwera.
Zotsatira zake, kuchuluka kwa insulin kumayambitsa kuphwanya njira zonse za thupi. Zomwe zimakhala zosasangalatsa makamaka kwa anthu omwe amakonda kuzala, metabolid metabolism amasokonezeka, zomwe zikutanthauza kuti mafuta amayamba kuyikiridwa mosavuta, ndipo mapaundi owonjezera amawonekera mofulumira.
Pankhaniyi, kutenga Metformin kuti muchepetse thupi kumawoneka ngati kotheka. Mankhwala amakhudza insulitivity insulin, zomwe zikutanthauza kuti amatha kuichepetsa. Zotsatira zake, kumwa kwa glucose m'maselo kumapangidwira, ndipo kuphatikiza kwakukulu kwa insulin kumakhala kotsekedwa. Zotsatira zake, zimapezeka kuti zimataya mapaundi owonjezera omwe amadanidwa - kulemerako kumabwereranso kwachilendo.
Kuphatikiza apo, mankhwalawa ali ndi anorexigenic - amathandiza kuchepetsa kulakalaka. Koma ndikofunikira kudziwa kuti si odwala onse omwe amamwa Metformin omwe amadziwa izi, chifukwa amadziwoneka wofooka kwambiri. Chifukwa chake, kutenga Metformin kokha ndikuyembekezera kupondereza chilakolako sichoyenera.
Muzochita zamankhwala, Metformin ya mankhwala yochizira kunenepa sikugwiritsidwa ntchito chifukwa chotsika mwayi wopeza zotsatira chifukwa cha kuphatikiza kwakukulu.
Kodi Metformin imathandizira kuchepetsa thupi?
Funso lodziwika kwa iwo omwe akufuna kuchepa makilogalamu ndiwotheka ngati zingatheke kuti muchepetse thupi potenga Metformin.
Ngakhale kutchulidwa kochepetsa shuga, Metformin sikuti nthawi zonse amathandizira kuchepetsa thupi. Musaiwale kuti cholinga chake ndi kuchiza matenda a shuga, ndipo ndi matendawa okha omwe ndi othandiza kwambiri. Chifukwa chake, kuchepa thupi kumawonedwa kwambiri odwala matenda ashuga kapena kunenepa kwambiri. Chifukwa chake, kutenga Metformin kwa woonda sikubweretsa zomwe mukufuna.
Kuphatikiza apo, simuyenera kusintha mankhwalawo kukhala mapiritsi amatsenga omwe amachiritsa matendawa popanda kuyesetsa kwa iye mwini. Ngati mukuyang'ana ndemanga za iwo omwe achepetsa thupi, zimapezeka kuti ambiri a iwo adatenga mankhwalawo ngati mankhwala a matenda a shuga, ndipo mapaundi owonjezera omwe atayika anali amodzi mwazinthu zomwe zasintha.
Kuti mankhwalawa adziwike, ndizofunikira kudya, komanso, kusintha pamakhalidwe ndikofunikira. Ndiye kuti, kuchepa thupi kumatheka popanda Metformin, ndipo mankhwalawa amatha kuchita zinthu zothandizira komanso kusangalatsa kwa njirayo. Zachidziwikire, kupatula milandu pamene kulemera kwambiri kumatsagana ndi matenda a shuga.
Komabe, ngati zili bwino m'maganizo kuti muchepe thupi mukamamwa mapiritsi, pomwe pali kuchuluka kwambiri kwa anthu osowa shuga, ndiye kuti muyenera kudziwa momwe mungatenge Metformin molondola kuti musavulaze thanzi lanu.
Malangizo a kumwa mankhwalawa
Patsamba lamasitolo ogulitsa mankhwala mutha kupeza mankhwala ochokera ku Metformin, operekedwa ndi makampani osiyanasiyana, omwe ali ndi ufulu kupereka dzina lawo ku mankhwalawo. Mwachitsanzo, Metformin Teva, Metformin Richter, Metformin Canon, etc. Popeza chinthu chachikulu pazopangidwazo ndi chimodzimodzi, mutha kusankha chilichonse, kapena analogues.
Mukamasankha, mutha kuyendayenda ndi mtengo wa mankhwalawo, ndikusankha yoyenera kwambiri pamtengo. Ndikofunika kulingalira momwe mankhwalawo amapangidwira, chifukwa zomwe zimapangidwira ndizosiyana, ndipo zimatha kuyambitsa zovuta kapena kuyambitsa ziwengo.
Ndiye ndikofunikira kudziwa kuchuluka kwa zomwe muyenera kutenga Metformin. Mankhwala amapezeka m'mitundu itatu: 500, 850 kapena 1000 mg ya mankhwala othandizira. Ndikulimbikitsidwa kuti ndiyambe ndi mlingo yaying'ono wa 500 mg. Osayesa zolimba kwambiri ndipo nthawi yomweyo yambani kulandira chithandizo ndi Metformin 1000, chifukwa izi zimatha kuyambitsa mavuto.
Mlingo wa Metformin umakwera pang'onopang'ono, masiku asanu ndi awiri aliwonse pa 500 mg. Mlingo woyenera wovomerezeka ndi 3000 mg patsiku, koma nthawi zambiri amalimbikitsidwa kuti achedwetse mpaka 2000 mg. Kuchulukitsa kuchuluka kwa mankhwalawa kungakhale koopsa, chifukwa kuyambitsa chiwonetsero champhamvu.
Mutha kutenga Metformin nthawi kapena mukatha kudya.
Palinso njira yakumwa mankhwalawa musanagone - ndilolondola, ndipo njirayi ikhoza kutsatira.
Ndemanga za madotolo za mankhwalawa
Ngati mukuyang'ana kuwunika kwa madotolo, amakayikira kwambiri pakugwiritsa ntchito Metformin pakuchepetsa thupi. Kutsitsa kwa shuga kwa mankhwalawa kumawonekera bwino ndipo amawona odwala onse. Kuphatikiza apo, Metformin imapondaponda ghrelin - mahomoni am'malo a njala, chifukwa chomwe mutha kuyang'anira kudya kwanu komanso kupewa kudya kwambiri. Koma izi sizitanthauza kuti ndizotheka kuchepetsa thupi kokha mothandizidwa ndi mankhwalawa.
Kuphatikiza apo, madotolo amawona kuti mphamvu ya mankhwalawa imasiyanasiyana kutengera wopanga, chifukwa chake sizingakhale chifukwa ichi.
Nthawi zina, madokotala samatsutsa kwenikweni kugwiritsa ntchito Metformin kuti achepetse thupi, koma nthawi yomweyo, malangizo amalimbikitsidwa kwa iwo omwe amachepetsa thupi, kutsatira zomwe zingathandize kupititsa nthawi yochepetsa thupi kwambiri.
Zingawonekere kuti mumadya zomwe mukufuna kwinaku kuchepa thupi. M'malo mwake, izi siziri choncho. Mukamatenga Metformin, tikulimbikitsidwa kuti tisinthe kwambiri m'moyo:
- Kuchita masewera olimbitsa thupi ndizovomerezeka, chifukwa amathandizira kayendedwe ka glucose m'maselo a minofu.
- Zakudya zina zimayenera kukhala zopanda zakudya. Choyamba, zonse zotsekemera kwambiri zapamwamba kwambiri, zakudya za ufa zimaletsedwa. Muyenera kuchepetsa kugwiritsa ntchito mafuta ochulukirapo (supuni yamafuta am'madzi siziwerengera). Magawo amafunikanso kuyang'aniridwa.
- Imwani madzi ambiri, chifukwa amathandizira kuchotsa zinthu zovulaza m'thupi zomwe zimamasulidwa "pakuwotcha" mafuta ochulukirapo, potero kupewa kuledzera.
- Nthawi yakumwa mankhwala ochepetsa thupi pa Metformin sayenera kupitirira masiku 20.
Zoyenera, kumwa mankhwala ochepetsa thupi ayenera kuyankhidwa moyenera. Chithandizo chiyenera kuyang'aniridwa ndi dokotala. Adzakuthandizani kusankha njira yabwino kwambiri komanso mulingo woyenera. Mwachitsanzo, iwo omwe ali onenepa kwambiri amafuna mlingo waukulu kuposa munthu woonda amene amangokhala ndi vuto lotha kunenepa kwambiri komanso ali ndi shuga wambiri.
Mwambiri, akatswiri amakhala owopa kwambiri chidwi cha odwala ena omwe alibe shuga kuti agwiritse ntchito Metformin kuti achepetse thupi. Kutsatsa kofala kuti mankhwalawa amathandizira kuchepetsa thupi popanda kudya mankhwala a shuga, sikuti ndi njira yotsatsira.
Sizotheka kuti muchepetse thupi mwa kumwa mankhwala okha a Metformin, ndipo nthawi yomweyo muzidya zinthu zovulaza. Kuti mankhwalawa apereke zomwe akufunazo, njira yovuta ndiyofunikira: kuphatikiza zakudya, kudya zolimbitsa thupi ndi kugwiritsa ntchito madzi ambiri.
Koma, kutsatira malangizowa, mutha kupeza zotsatira zabwino popanda kumwa mankhwalawa, omwe, kuwonjezera apo, angayambitse mavuto.
Ndemanga Zamakasitomala a Metformin
Mwa ogula omwe amamwa mapiritsi a Metformin, nawonso ndemanga za 2017 ndizosiyanasiyana. Pakati pawo, pali zabwino.
Kwa kanthawi tsopano ndamwa Metformin monga adanenera dokotala. Zotsatira zake zinali zodabwitsa. Amamva bwino, ndipo koposa zonse, iyenso sanazindikire momwe adapopera 5 kg.
Metformin anamwa mankhwala atachira kuchipatala. Kulemera kunatsika pafupifupi 8 kg! Sindinamvetsetse nthawi yomweyo chifukwa chake, kenako ndidawerenga malangizo a mankhwalawo - zidapezeka kuti Metformin imathandizira kuchepetsa thupi. Kuphatikiza apo, ndinayamba kudya kwambiri, chifukwa chake, mwina zoterezi.
Iwo omwe adachepetsa thupi mothandizidwa ndi Metformin adazindikira kuti mankhwalawa amathandizanso kuchepa mapaundi owonjezera, koma kuti mupeze zotsatira, muyenera kuyesetsa kwambiri ndikuyang'anira thanzi lanu, makamaka ngati mankhwalawo adagulidwa popanda mankhwala. Kuchepetsa thupi pamaphunziro onse, masiku 20, ndi 10 makilogalamu, koma kuti muchepetse kulemera, zonse zolimbitsa thupi ndikusintha menyu ndikofunikira.
Odwala ena omwe amachepetsa thupi ndi Metformin sanazindikire kusiyana kwakukulu pakutenga Metformin ndi mankhwala ena kuti achepetse thupi. Ubwino wake unali mtengo wa mankhwalawo poyerekeza ndi mtengo wa zakudya zina zothandizira pakudya.
Gulu la odwala omwe adaganiza zochepetsa thupi pogwiritsa ntchito Metformin adalephera kukwaniritsa zotsatira zomwe amafunazo, koma palibe zotsatira zoyipa zomwe zidawonedwa.
Amayi akhala akumwa Metformin Zentiva wa matenda ashuga kwa zaka zingapo. Ndipo china chake kuchepa thupi sichimawonedwa.
Ndemanga zoyipa sizachilendo. Choyamba, iwo omwe adachepetsa thupi sawona kusintha kulikonse pa kulemera. Koma mavuto enanso adawonekera. Odwala ambiri adadandaula za kukhumudwa m'mimba. Mavuto ena nthawi zambiri ankatsatiridwa ndi mavuto ena, monga nseru, kufooka, ulesi, alopecia (kutaya kwambiri tsitsi).
Zotsatira zake, titha kunena kuti Metformin, monga mankhwala ena "othandiza kwambiri" kapena zakudya zaposachedwa kwambiri, sizipereka mphamvu, koma zitha kuyambitsa mavuto osiyanasiyana azaumoyo. Simuyenera kugwiritsa ntchito mankhwalawa kukonza vuto lomwe silinakumane nalo.
Momwe Metformin amathandizira afotokozedwera akatswiri mu kanema munkhaniyi.
